Publications,References

DNA methylome, R-loop and clinical exome profiling of patients with...
Published: January, 2024

Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the death of motor neurons, the aetiology of which is es... Read more »

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Premium RRBS Kit

Gestational Caloric Restriction Alters Adipose Tissue Methylome and...
Published: January, 2024

Abstract: Limited nutrient supply to the fetus results in physiologic and metabolic adaptations that have unfavorable consequences in the offspring. In a swi... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Matched analysis of detailed peripheral blood and tumor immune micr...
Published: January, 2024

Abstract: Background: Bladder cancer and therapy responses hinge on immune profiles in the tumor microenvironment (TME) and blood, yet studies linking t... Read more »

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Infinium Human MethylationEPIC Array Service

Integrative functional genomic analyses identify genetic variants i...
Published: January, 2024

Abstract: Skin color is highly variable in Africans, yet little is known about the underlying molecular mechanism. Here we applied massively parallel reporte... Read more »

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Tagmentase

An inappropriate decline in ribosome levels drives a diverse set of...
Published: January, 2024

Abstract: Many neurodevelopmental defects are linked to perturbations in genes involved in housekeeping functions, such as those encoding ribosome biogenesis... Read more »

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D-Plex small RNA-seq

Promoter DNA methylation patterns in oral, laryngeal and oropharyng...
Published: January, 2024

Abstract: Differentially methylated regions (DMRs) can be used as head and neck squamous cell carcinoma (HNSCC) diagnostic, prognostic and therapeutic target... Read more »

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MagMeDIP kit

Substrate stiffness promotes vascular smooth muscle cell calcificat...
Published: January, 2024

Abstract: Background: Vascular calcification (VC) is a prevalent independent risk factor for adverse cardiovascular events and is associated with diabet... Read more »

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iDeal ChIP-qPCR

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pl...
Published: January, 2024

Abstract: Human naïve pluripotent stem cells (nPSCs) can differentiate into extra-embryonic trophectoderm (TE), a critical step in the generation of the... Read more »

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ATAC-seq

Diagnostic Algorithm to Subclassify Atypical Spitzoid Tumors in Low...
Published: December, 2023

Abstract: Current diagnostic algorithms are insufficient for the optimal clinical and therapeutic management of cutaneous spitzoid tumors, particularly atypi... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

The ncBAF complex regulates transcription in AML through H3K27ac se...
Published: December, 2023

Abstract: The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemog... Read more »

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Tagmentase

In vitro production of cat-restricted Toxoplasma pre-sexual stages
Published: December, 2023

Abstract: Sexual reproduction of Toxoplasma gondii, confined to the felid gut, remains largely uncharted owing to ethical concerns regarding the use of ... Read more »

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Antibody IPure kit iDeal ChIP-seq Kit for Transcription Factors ATAC-seq

Challenges in characterization of transcriptomes of extracellular v...
Published: December, 2023

Abstract: Since its original discovery over a decade ago, extracellular RNA (exRNA) has been found in all biological fluids. Furthermore, extracellular micro... Read more »

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D-Plex small RNA-seq

SMARCB1 loss activates patient-specific distal oncogenic enhancers ...
Published: December, 2023

Abstract: Malignant rhabdoid tumor (MRT) is a highly malignant and often lethal childhood cancer. MRTs are genetically defined by bi-allelic inactivating mut... Read more »

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Microplex Library Preparation kit

The genetic landscape of origins of replication in P. falciparum
Published: December, 2023

Abstract: Various origin mapping approaches have enabled genome-wide identification of origins of replication (ORI) in model organisms, but only a few studie... Read more »

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Microplex Library Preparation kit

DAXX promotes centromeric stability independently of ATRX by preven...
Published: December, 2023

Abstract: Maintaining chromatin integrity at the repetitive non-coding DNA sequences underlying centromeres is crucial to prevent replicative stress, DNA bre... Read more »

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iDeal ChIP-qPCR

An enriched maternal environment and stereotypies of sows different...
Published: December, 2023

Abstract: Epigenetic mechanisms are important modulators of neurodevelopmental outcomes in the offspring of animals challenged during pregnancy. Pregnant sow... Read more »

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Antibody

Association of DNA methylation signatures with premature ageing and...
Published: December, 2023

Abstract: Patients with end-stage kidney disease (ESKD) display features of premature aging. There is strong evidence that changes in DNA methylation (DNAm) ... Read more »

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Infinium Human MethylationEPIC Array Service

SUMO protease FUG1, histone reader AL3 and the PRC1 Complex areinte...
Published: December, 2023

Abstract: Epigenetic gene silencing induced by expanded repeats can cause diverse phenotypes ranging from severe growth defects in plants to genetic diseases... Read more »

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Antibody

KDM6B drives epigenetic reprogramming associated with lymphoid stro...
Published: November, 2023

Abstract: Mature lymphoid stromal cells (LSCs) are key organizers of immune responses within secondary lymphoid organs. Similarly, inflammation-driven tertia... Read more »

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Antibody

LEO1 Is Required for Efficient Entry into Quiescence, Control of H3...
Published: November, 2023

Abstract: (1) Background: The LEO1 (Left open reading frame 1) protein is a conserved subunit of the PAF1C complex (RNA polymerase II-associated factor 1 com... Read more »

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iDeal ChIP-seq Kit for Histones

Guidelines for Performing Ribosome Profiling in Plants Including St...
Published: November, 2023

Abstract: Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Across differen... Read more »

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D-Plex small RNA-seq

Integrated multiplexed assays of variant effect reveal cis-regulato...
Published: November, 2023

Abstract: Multiplexed assays of variant effect are powerful methods to profile the consequences of rare variants on gene expression and organismal fitness. Y... Read more »

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D-Plex small RNA-seq

H3K9 methylation patterns during somatic embryogenic competenceexpr...
Published: November, 2023

Abstract: The capacity to regenerate is intrinsic to plants and is the basis of natural asexual propagation and artificial cloning. Despite there are differe... Read more »

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Antibody

The Ribosome Assembly Factor Reh1 is Released from the Polypeptide ...
Published: October, 2023

Abstract: Assembly of functional ribosomal subunits and successfully delivering them to the translating pool is a prerequisite for protein synthesis and cell... Read more »

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D-Plex small RNA-seq

Inflammatory stress-mediated chromatin changes underlie dysfunction...
Published: October, 2023

Abstract: Inflammatory stresses underlie endothelial dysfunction and contribute to the development of chronic cardiovascular disorders such as atherosclerosi... Read more »

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Chromatin Profiling (ChIP-seq) Services ATAC-seq

A transgenic mice model of retinopathy of cblG-type inherited disor...
Published: October, 2023

Abstract: BACKGROUND: MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolis... Read more »

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Newly added

G-quadruplexes of KSHV oriLyt play important roles in promoting lyt...
Published: October, 2023

Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes distinct origins of DNA replication (origin of replications) during the latent and lytic ph... Read more »

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Newly added

ARID1A governs the silencing of sex-linked transcription during mal...
Published: September, 2023

Abstract: We present evidence implicating the BAF (BRG1/BRM Associated Factor) chromatin remodeler in meiotic sex chromosome inactivation (MSCI). By immunofl... Read more »

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Tagmentase

Knockout of the longevity gene Klotho perturbs aging- and Alzheimer...
Published: September, 2023

Abstract: Overexpression of the longevity gene Klotho prolongs, while its knockout shortens lifespan and impairs cognition via altered fibroblast growth fact... Read more »

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D-Plex small RNA-seq

A Type II-B Cas9 nuclease with minimized off-targets and reduced ch...
Published: September, 2023

Abstract: Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as genome editors, but their promiscuous nuclease activity often ... Read more »

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Tagmentase

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