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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Accurate circular consensus long-read sequencing improves variant d...
Published: August, 2019

Abstract: The DNA sequencing technologies in use today produce either highly accurate short reads or less-accurate long reads. We report the optimization of ... Read more »

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Megaruptor
Free heme regulates placenta growth factor through NRF2-antioxidant...
Published: August, 2019

Abstract: Free heme activates erythroblasts to express and secrete Placenta Growth Factor (PlGF), an angiogenic peptide of the VEGF family. High circulating ... Read more »

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Antibody
EZH2 as a novel therapeutic target for atrial fibrosis and atrial f...
Published: August, 2019

Abstract: Angiotensin II (Ang-II)-induced fibroblast differentiation plays an important role in the development of atrial fibrosis and atrial fibrillation (A... Read more »

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HighCell ChIP kit IPure kit
Transit amplifying cells coordinate mouse incisor mesenchymal stem ...
Published: August, 2019

Abstract: Stem cells (SCs) receive inductive cues from the surrounding microenvironment and cells. Limited molecular evidence has connected tissue-specific m... Read more »

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Antibody
Clinicopathological evaluation of PD-L1 expression and cytotoxic T-...
Published: August, 2019

Abstract: Immune check-point blockade (ICB) targeting programmed cell death ligand-1 (PD-L1)/programmed death-1 (PD-1) axis has created paradigm shift in can... Read more »

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IPure kit
Proteomics Links Ubiquitin Chain Topology Change to Transcription F...
Published: August, 2019

Abstract: A surprising complexity of ubiquitin signaling has emerged with identification of different ubiquitin chain topologies. However, mechanisms of how ... Read more »

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Bioruptor
Interaction of Sox2 with RNA binding proteins in mouse embryonic st...
Published: August, 2019

Abstract: Sox2 is a master transcriptional regulator of embryonic development. In this study, we determined the protein interactome of Sox2 in the chromatin ... Read more »

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True MicroChIP kit Beads
Functional dissection of the Sox9-Kcnj2 locus identifies nonessenti...
Published: August, 2019

Abstract: The genome is organized in three-dimensional units called topologically associating domains (TADs), through a process dependent on the cooperative ... Read more »

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Antibody
Regulation of Co-transcriptional Pre-mRNA Splicing by mA through th...
Published: July, 2019

Abstract: N-methyladenosine (mA) modification occurs co-transcriptionally and impacts pre-mRNA processing; however, the mechanism of co-transcriptional mA-de... Read more »

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Bioruptor
EOMES interacts with RUNX3 and BRG1 to promote innate memory cell f...
Published: July, 2019

Abstract: Memory CD8 T cells have the ability to provide lifelong immunity against pathogens. Although memory features generally arise after challenge with a... Read more »

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Microplex Library Preparation kit
Activation of neuronal genes via LINE-1 elements upon global DNA de...
Published: July, 2019

Abstract: DNA methylation contributes to the maintenance of genomic integrity in somatic cells, in part through the silencing of transposable elements. In th... Read more »

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Antibody
Class I TCP transcription factors target the gibberellin biosynthes...
Published: July, 2019

Abstract: Plants respond to a rise in ambient temperature by increasing the growth of petioles and hypocotyls. In this work, we show that Arabidopsis thalian... Read more »

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Antibody
Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate...
Published: July, 2019

Abstract: Mammalian gametogenesis involves dramatic and tightly regulated chromatin remodeling, whose regulatory pathways remain largely unexplored. Here, we... Read more »

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OneDay ChIP Kit
Reference genome and comparative genome analysis for the WHO refere...
Published: July, 2019

Abstract: BACKGROUND: Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effor... Read more »

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Megaruptor
Aberrant expression of imprinted lncRNA MEG8 causes trophoblast dys...
Published: July, 2019

Abstract: Long noncoding RNAs (lncRNAs) are a group of noncoding RNAs whose nucleotides are longer than 200 bp. Previous studies have shown that they ... Read more »

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Antibody
Development and epigenetic plasticity of murine Müller glia.
Published: July, 2019

Abstract: The ability to regenerate the entire retina and restore lost sight after injury is found in some species and relies mostly on the epigenetic plasti... Read more »

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Antibody IP-Star Compact Microplex Library Preparation kit True MicroChIP kit Chromatin Profiling (ChIP-seq) Services
The Toxoplasma effector TEEGR promotes parasite persistence by modu...
Published: July, 2019

Abstract: The protozoan parasite Toxoplasma gondii has co-evolved with its homeothermic hosts (humans included) strategies that drive its quasi-asymptomatic ... Read more »

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Antibody IPure kit iDeal ChIP-seq Kit for Transcription Factors
Whsc1 links pluripotency exit with mesendoderm specification.
Published: July, 2019

Abstract: How pluripotent stem cells differentiate into the main germ layers is a key question of developmental biology. Here, we show that the chromatin-rel... Read more »

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True MicroChIP kit
Elevated cyclic-AMP represses expression of exchange protein activa...
Published: June, 2019

Abstract: Ligand-induced activation of Exchange Protein Activated by cAMP-1 (EPAC1) is implicated in numerous physiological and pathological processes, inclu... Read more »

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Antibody
Genome-wide methylation in alcohol use disorder subjects: implicati...
Published: June, 2019

Abstract: Environmental factors, including substance abuse and stress, cause long-lasting changes in the regulation of gene expression in the brain via epige... Read more »

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MagMeDIP kit Antibody
Long-read based de novo assembly of low-complexity metagenome sampl...
Published: June, 2019

Abstract: BACKGROUND: Complete and contiguous genome assemblies greatly improve the quality of subsequent systems-wide functional profiling studies and the a... Read more »

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Megaruptor
Droplet-based combinatorial indexing for massive-scale single-cell ...
Published: June, 2019

Abstract: Recent technical advancements have facilitated the mapping of epigenomes at single-cell resolution; however, the throughput and quality of these me... Read more »
p73 regulates epidermal wound healing and induced keratinocyte prog...
Published: June, 2019

Abstract: p63 is a transcriptional regulator of ectodermal development that is required for basal cell proliferation and stem cell maintenance. p73 is a clos... Read more »

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Bioruptor
ARID1A facilitates KRAS signaling-regulated enhancer activity in an...
Published: June, 2019

Abstract: BACKGROUND: ARID1A (AT-rich interactive domain-containing protein 1A) is a subunit of the BAF chromatin remodeling complex and plays roles in trans... Read more »

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Microplex Library Preparation kit CATS
The alarmin S100A9 hampers osteoclast differentiation from human ci...
Published: June, 2019

Abstract: The alarmin S100A8/A9 is implicated in sterile inflammation-induced bone resorption and has been shown to increase the bone-resorptive capacity of ... Read more »

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Antibody
Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered ...
Published: June, 2019

Abstract: The deubiquitinating enzyme BAP1 is a tumor suppressor, among others involved in cholangiocarcinoma. BAP1 has many proposed molecular targets, whil... Read more »

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Antibody
Resveratrol up-regulates ATP2A3 gene expression in breast cancer ce...
Published: June, 2019

Abstract: Resveratrol (RSV) is a phytoestrogen which has been related to chemoprevention of several types of cancer. In this work, we show up to a 6-fold inc... Read more »

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OneDay ChIP Kit
DNA methylation of the Tacr2 gene in a CUMS model of depression.
Published: June, 2019

Abstract: Tacr2, the gene encoding the NK2 receptor, belongs to G protein-coupled receptors. Accumulating evidence has indicated that the tachykinin receptor... Read more »

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MagMeDIP kit
Characterization of the salmon louse Lepeophtheirus salmonis miRNom...
Published: June, 2019

Abstract: The salmon louse Lepeophtheirus salmonis is a marine ectoparasite that has a detrimental impact on salmon farms. Genomic knowledge of adult stages ... Read more »

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CATS
A chromosome-scale genome assembly of cucumber (Cucumis sativus L.).
Published: June, 2019

Abstract: BACKGROUND: Accurate and complete reference genome assemblies are fundamental for biological research. Cucumber is an important vegetable crop and ... Read more »

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Megaruptor

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