Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Lamin B1 mapping reveals the existence of dynamic and functional eu...
Published: August, 2018

Abstract: Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic... Read more »

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Beads
Progenitor Hyperpolarization Regulates the Sequential Generation of...
Published: August, 2018

Abstract: During corticogenesis, ventricular zone progenitors sequentially generate distinct subtypes of neurons, accounting for the diversity of neocortical... Read more »

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Antibody
Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: ...
Published: August, 2018

Abstract: BACKGROUND: Many neurodegenerative diseases are caused by nucleotide repeat expansions, but most expansions, like the C9orf72 'GGGGCC' (GC) repeat ... Read more »

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Megaruptor
Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response ...
Published: August, 2018

Abstract: Activation of macrophages by inflammatory stimuli induces reprogramming of mitochondrial metabolism to support the production of pro-inflammatory c... Read more »

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Antibody
The complete methylome of an entomopathogenic bacterium reveals the...
Published: August, 2018

Abstract: DNA methylation can serve to control diverse phenomena in eukaryotes and prokaryotes, including gene regulation leading to cell differentiation. In... Read more »

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Megaruptor
Loss of SETDB1 decompacts the inactive X chromosome in part through...
Published: August, 2018

Abstract: BACKGROUND: The product of dosage compensation in female mammals is the inactive X chromosome (Xi). Xi facultative heterochromatin is organized int... Read more »

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Antibody
The Alzheimer's disease-associated TREM2 gene is regulated by p53 t...
Published: August, 2018

Abstract: TREM2 mutations evoke neurodegenerative disorders, and recently genetic variants of this gene were correlated to increased risk of Alzheimer's dise... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
Genome-wide association study identifies multiple new loci associat...
Published: August, 2018

Abstract: Ewing sarcoma (EWS) is a pediatric cancer characterized by the EWSR1-FLI1 fusion. We performed a genome-wide association study of 733 EWS cases and... Read more »

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iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.
Published: August, 2018

Abstract: Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to... Read more »

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OneDay ChIP Kit
Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.
Published: August, 2018

Abstract: Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to... Read more »

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OneDay ChIP Kit
The Arabidopsis LDL1/2-HDA6 histone modification complex is functio...
Published: August, 2018

Abstract: In Arabidopsis, the circadian clock central oscillator genes are important cellular components to generate and maintain circadian rhythms. There is... Read more »

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Antibody
Canonical PRC2 function is essential for mammary gland development ...
Published: August, 2018

Abstract: Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone ... Read more »

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Antibody
The histone demethylase Jarid1b mediates angiotensin II-induced end...
Published: August, 2018

Abstract: AIM: The histone demethylase Jarid1b limits gene expression by removing the active methyl mark from histone3 lysine4 at gene promoter regions. A va... Read more »

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ChIP-qPCR
Long-read sequence capture of the haemoglobin gene clusters across ...
Published: August, 2018

Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »

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Megaruptor
The effect of Jun dimerization on neurite outgrowth and motif binding.
Published: August, 2018

Abstract: Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known ... Read more »

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ChIP-qPCR
The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic t...
Published: August, 2018

Abstract: Chromatin remodeler Brahma related gene 1 (BRG1) is silenced in approximately 10% of human pancreatic ductal adenocarcinomas (PDAs). We previously ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Novel dual regulators of Pseudomonas aeruginosa essential for produ...
Published: August, 2018

Abstract: Gene regulation network in Pseudomonas aeruginosa is complex. With a relatively large genome (6.2 Mb), there is a significant portion of genes that... Read more »

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Antibody
Identification of miR-379/miR-656 (C14MC) cluster downregulation an...
Published: August, 2018

Abstract: INTRODUCTION: Although role of individual microRNAs (miRNAs) in the pathogenesis of gliomas has been well studied, their role as a clustered remain... Read more »

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IPure kit
Automethylation-induced conformational switch in Clr4 (Suv39h) main...
Published: August, 2018

Abstract: Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and the regulation of gene e... Read more »

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Antibody True MicroChIP kit
Epigenetic regulation of brain region-specific microglia clearance ...
Published: August, 2018

Abstract: The rapid elimination of dying neurons and nonfunctional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain... Read more »

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IPure kit
HIV-2/SIV viral protein X counteracts HUSH repressor complex.
Published: August, 2018

Abstract: To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2) have evolved auxiliary proteins that target cell restrictio... Read more »

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Antibody HighCell ChIP kit
Atopic asthma after rhinovirus-induced wheezing is associated with ...
Published: August, 2018

Abstract: Children with rhinovirus-induced severe early wheezing have an increased risk of developing asthma later in life. The exact molecular mechanisms fo... Read more »

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Antibody IP-Star Compact
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scler...
Published: August, 2018

Abstract: OBJECTIVE: Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of met... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
The transcriptional factor ZEB1 represses Syndecan 1 expression in ...
Published: July, 2018

Abstract: Syndecan 1 (SDC-1) is a cell surface proteoglycan with a significant role in cell adhesion, maintaining epithelial integrity. SDC1 expression is in... Read more »

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Antibody
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-select...
Published: July, 2018

Abstract: ABSTACT: Polycomb-mediated repression of gene expression is essential for development, with a pivotal role played by trimethylation of histone H3 l... Read more »

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Antibody
TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Published: July, 2018

Abstract: Testis-specific protein, Y-encoded-like 2 (TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously sh... Read more »

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Antibody
Wnt receptor Frizzled 8 is a target of ERG in prostate cancer
Published: July, 2018

Abstract: Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men. Many molecular changes have been detailed during PCa progression. ... Read more »

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ChIP-qPCR
The transcription factor Lef1 switches partners from β-catenin to S...
Published: July, 2018

Abstract: Skeletal muscle stem cells (MuSCs), also known as satellite cells, persist in adult mammals by entering a state of quiescence (G) during the early ... Read more »

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LowCell ChIP kit
Longitudinal Effects of Developmental Bisphenol A Exposure on Epige...
Published: July, 2018

Abstract: BACKGROUND: Epigenetic machinery plays an important role in genomic imprinting, a developmental process that establishes parent-of-origin-specific ... Read more »
Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2...
Published: July, 2018

Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both ... Read more »

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Antibody

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