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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

ATRX regulates glial identity and the tumor microenvironment in IDH...
Published: November, 2021

Abstract: Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent... Read more »

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CUT&Tag
The ETS transcription factor ERF controls the exit from the naïve p...
Published: October, 2021

Abstract: The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this ... Read more »

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Premium RRBS Kit DNA Methylation
Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Ne...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service) DNA Methylation
Genome-wide epigenomic analyses in patients with nociceptive and ne...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

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DNA Methylation Profiling (RRBS Service)
Environmental enrichment preserves a young DNA methylation landscap...
Published: June, 2021

Abstract: The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve br... Read more »
Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Le...
Published: June, 2021

Abstract: Dyskinesias are characterized by abnormal repetitive involuntary movements due to dysfunctional neuronal activity. Although levodopa-induced dyskin... Read more »

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Premium RRBS Kit
Therapy-induced DNA methylation inactivates MCT1 and renders tumor ...
Published: June, 2021

Abstract: Metabolic plasticity in cancer cells makes use of metabolism-targeting agents very challenging. Drug-induced metabolic rewiring may, however, uncov... Read more »

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DNA Methylation Methylated DNA immunoprecipitation MagMeDIP qPCR Kit
ChIP-seq protocol for sperm cells and embryos to assess environment...
Published: June, 2021

Abstract: In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descend... Read more »

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Antibody
Familial thrombocytopenia due to a complex structural variant resul...
Published: June, 2021

Abstract: Advances in genome sequencing have resulted in the identification of the causes for numerous rare diseases. However, many cases remain unsolved wit... Read more »

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Megaruptor
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of...
Published: May, 2021

Abstract: Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely repor... Read more »

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Tagmentase
Vesicle-bound regulatory RNAs are associated with tissue aging
Published: May, 2021

Abstract: Previous work on murine models and human demonstrated global as well as tissue-specific molecular aging trajectories in solid tissues and body flui... Read more »

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D-Plex RNA-seq kit
HOTAIR lncRNA promotes epithelial-mesenchymal transition byredistri...
Published: May, 2021

Abstract: Epithelial-to-mesenchymal transition (EMT) describes the loss of epithelial traits and gain of mesenchymal traits by normal cells during developmen... Read more »

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Antibody
The lncRNA and the transcription factor WRKY42 target common cell ...
Published: May, 2021

Abstract: Plant long noncoding RNAs (lncRNAs) are key chromatin dynamics regulators, directing the transcriptional programs driving a wide variety of develop... Read more »

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Antibody
Placental uptake and metabolism of 25(OH)Vitamin D determines itsac...
Published: May, 2021

Abstract: Pregnancy 25-hydroxyvitamin D (25(OH)D) concentrations are associated with maternal and fetal health outcomes, but the underlying mechanisms have n... Read more »

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Antibody
Chromatin accessibility governs the differential response of cancer...
Published: May, 2021

Abstract: Depleting the microenvironment of important nutrients such as arginine is a key strategy for immune evasion by cancer cells. Many tumors overexpres... Read more »

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Antibody
Sarcomere function activates a p53-dependent DNA damage response th...
Published: May, 2021

Abstract: Human cardiac regeneration is limited by low cardiomyocyte replicative rates and progressive polyploidization by unclear mechanisms. To study this ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Published: May, 2021

Abstract: Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to so... Read more »

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Antibody
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at ...
Published: April, 2021

Abstract: Analyzing all features of small non-coding RNA sequencing data can be demanding and challenging. To facilitate this process, we developed miRMaster... Read more »

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small non-coding RNA sequencing analysis microRNA miRNA prediction bioinformatic tools D-Plex RNA-seq kit
Enhanced cell deconvolution of peripheral blood using DNA methylati...
Published: April, 2021

Abstract: DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution ... Read more »

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DNA methylation microarray Immune profiling
Interplay between Histone and DNA Methylation Seen through Comparat...
Published: April, 2021

Abstract: DNA methylation (DNAme) profiling is used to establish specific biomarkers to improve the diagnosis of patients with inherited neurodevelopmental d... Read more »

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Rare diseases Neurodevelopment disorders DNA methylation microarray Biomarker discovery
Androgen and glucocorticoid receptor direct distinct transcriptiona...
Published: April, 2021

Abstract: The glucocorticoid (GR) and androgen (AR) receptors execute unique functions in vivo, yet have nearly identical DNA binding specificities. To ident... Read more »

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Antibody
Chromosomal inversion polymorphisms in two sympatric ascidian linea...
Published: April, 2021

Abstract: Chromosomal rearrangements can reduce fitness of heterozygotes and can thereby prevent gene flow. Therefore, such rearrangements can play a role in... Read more »

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Megaruptor
USP22 Suppresses Expression in Acute Colitis and Inflammation-Asso...
Published: April, 2021

Abstract: As a member of the 11-gene "death-from-cancer" gene expression signature, ubiquitin-specific protease 22 (USP22) has been considered an oncogene in... Read more »

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Antibody
PCIP-seq: simultaneous sequencing of integrated viral genomes and t...
Published: April, 2021

Abstract: The integration of a viral genome into the host genome has a major impact on the trajectory of the infected cell. Integration location and variatio... Read more »

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Megaruptor
Waves of sumoylation support transcription dynamics during adipocyt...
Published: April, 2021

Abstract: Tight control of gene expression networks required for adipose tissue formation and plasticity is essential for adaptation to energy needs and envi... Read more »

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Microplex Library Preparation kit
Sensitive and reproducible cell-free methylome quantification with ...
Published: April, 2021

Abstract: Background. Cell-free methylated DNA immunoprecipitation-sequencing (cfMeDIP-seq) identifies genomic regions with DNA methylation, using a protocol... Read more »

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Antibody
Complex-dependent histone acetyltransferase activity of KAT8 determ...
Published: April, 2021

Abstract: Acetylation of lysine 16 on histone H4 (H4K16ac) is catalyzed by histone acetyltransferase KAT8 and can prevent chromatin compaction in vitro.... Read more »

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Antibody
The anti-inflammatory cytokine interleukin-37 is an inhibitor of tr...
Published: April, 2021

Abstract: Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/macrophages by exposure to pathogens or vaccines, which evolv... Read more »

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Antibody
Androgen receptor positively regulates gonadotropin-releasing hormo...
Published: April, 2021

Abstract: Within pituitary gonadotropes, the gonadotropin-releasing hormone receptor (GnRHR) receives hypothalamic input from GnRH neurons that is critical f... Read more »

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ChIP Cross-link Gold
Dynamic association of the H3K64 trimethylation mark with genes enc...
Published: April, 2021

Abstract: Epigenetic modifications have emerged as critical regulators of virulence genes and stage-specific gene expression in Plasmodium falciparum. Howeve... Read more »

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Antibody

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