Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valpr...
Published: October, 2017

Abstract: Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs in the world. Despite its pharmacological importance, it may cause liv... Read more »

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MagMeDIP kit IPure kit
Genome methylation and regulatory functions for hypoxic adaptation...
Published: October, 2017

Abstract: Tibetan chickens have unique adaptations to the extreme high-altitude environment that they inhabit. Epigenetic DNA methylation affects many biolog... Read more »

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MagMeDIP kit
De novo PacBio long-read and phased avian genome assemblies correct...
Published: October, 2017

Abstract: Reference-quality genomes are expected to provide a resource for studying gene structure, function, and evolution. However, often genes of interest... Read more »

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Megaruptor
TET2- and TDG-mediated changes are required for the acquisition of ...
Published: September, 2017

Abstract: The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MAC... Read more »

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Antibody LowCell ChIP kit
In trans paired nicking triggers seamless genome editing without do...
Published: September, 2017

Abstract: Precise genome editing involves homologous recombination between donor DNA and chromosomal sequences subjected to double-stranded DNA breaks made b... Read more »

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Antibody
Histone H4K20 tri-methylation at late-firing origins ensures timely...
Published: September, 2017

Abstract: Among other targets, the protein lysine methyltransferase PR-Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate f... Read more »

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Antibody
UV Radiation Activates Toll-Like Receptor 9 Expression in Primary H...
Published: September, 2017

Abstract: Several lines of evidence indicate that cutaneous human papillomavirus (HPV) types belonging to the beta genus of the HPV phylogenetic tree synergi... Read more »
5-hydroxymethylcytosine accumulation in postmitotic neurons results...
Published: September, 2017

Abstract: 5-hydroxymethylcytosine (5hmC) occurs at maximal levels in postmitotic neurons, where its accumulation is cell-specific and correlated with gene ex... Read more »

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LowCell ChIP kit
The cardiac calsequestrin gene transcription is modulated at the pr...
Published: September, 2017

Abstract: Calsequestrin-2 (CASQ2) is the main Ca2+-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-... Read more »

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ChIP-seq
The CCAAT box in the proximal SERCA2 gene promoter regulates basal ...
Published: September, 2017

Abstract: The cardiac sarco/endoplasmic reticulum Ca2+-ATPase-2a (SERCA2a) is vital for the correct handling of calcium concentration in cardiomyocytes. Rece... Read more »
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate ...
Published: September, 2017

Abstract: Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition, and a ca... Read more »

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ChIP-seq
DNA methylation of intragenic CpG islands depends on their transcri...
Published: September, 2017

Abstract: The human genome contains ∼30,000 CpG islands (CGIs). While CGIs associated with promoters nearly always remain unmethylated, many of the ∼... Read more »

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Antibody
Distinct Circadian Signatures in Liver and Gut Clocks Revealed by K...
Published: September, 2017

Abstract: The circadian clock orchestrates rhythms in physiology and behavior, allowing organismal adaptation to daily environmental changes. While food inta... Read more »

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Antibody
The Hox proteins Ubx and AbdA collaborate with the transcription pa...
Published: September, 2017

Abstract: In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulatio... Read more »
A lipodystrophy-causing lamin A mutant alters conformation and epig...
Published: September, 2017

Abstract: Mutations in the Lamin A/C (LMNA) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic s... Read more »

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Antibody
Transcription of synaptic plasticity-related genes in patients with...
Published: September, 2017

Abstract: Objective: To investigate DNA methylation and hydroxymethylation in patients with somnipathy combined with type 2 diabetes, and to explore the effe... Read more »

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MeDIP kit
High-Resolution Chromatin Immunoprecipitation: ChIP-Sequencing
Published: September, 2017

Abstract: Chromatin immunoprecipitation (ChIP) coupled with next-generation sequencing (NGS) is widely used for studying the nucleoprotein components that ar... Read more »

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IPure kit
Epigenome profiling and editing of neocortical progenitor cells dur...
Published: September, 2017

Abstract: The generation of neocortical neurons from neural progenitor cells (NPCs) is primarily controlled by transcription factors binding to DNA in the co... Read more »

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LowCell ChIP kit IPure kit Microplex Library Preparation kit
SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus...
Published: August, 2017

Abstract: The structural maintenance of chromosomes (SMC) complex plays an important role in chromosome organization and segregation in most living organisms... Read more »

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ChIP-qPCR
Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits in...
Published: August, 2017

Abstract: Abstract Problem Heightened maternal stress affects trophoblast function and increases risk for adverse pregnancy outcomes. Methods of Stu... Read more »
Epigenetic variation between urban and rural populations of Darwin'...
Published: August, 2017

Abstract: Background The molecular basis of evolutionary change is assumed to be genetic variation. However, growing evidence suggests that epigenetic m... Read more »

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Antibody
Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichme...
Published: August, 2017

Abstract: Background Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure... Read more »

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MagMeDIP kit
A lncRNA fine tunes the dynamics of a cell state transition involvi...
Published: August, 2017

Abstract: Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated f... Read more »

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Antibody
Myc Regulates Chromatin Decompaction and Nuclear Architecture durin...
Published: August, 2017

Abstract: 50 years ago, Vincent Allfrey and colleagues discovered that lymphocyte activation triggers massive acetylation of chromatin. However, the molecula... Read more »

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Antibody
Transcriptome sequencing in pediatric acute lymphoblastic leukemia ...
Published: August, 2017

Abstract: BACKGROUND: Structural chromosomal rearrangements that lead to expressed fusion genes are a hallmark of acute lymphoblastic leukemia (ALL). In t... Read more »

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Microplex Library Preparation kit
Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in hum...
Published: August, 2017

Abstract: Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (... Read more »

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Antibody
High Resolution Mapping of Chromatin Conformation in Cardiac Myocyt...
Published: August, 2017

Abstract: Background -Cardiovascular disease is associated with epigenomic changes in the heart, however the endogenous structure of cardiac myocyte chromati... Read more »

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Antibody
Circadian Reprogramming in the Liver Identifies Metabolic Pathways ...
Published: August, 2017

Abstract: The process of aging and circadian rhythms are intimately intertwined, but how peripheral clocks involved in metabolic homeostasis contribute to ag... Read more »

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Antibody
Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-...
Published: August, 2017

Abstract: BACKGROUND: The epithelial-to-mesenchymal transition (EMT) enables epithelial cancer cells to acquire mesenchymal features and contributes to me... Read more »

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Antibody
Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methy...
Published: August, 2017

Abstract: During cellular differentiation, genes important for differentiation are expected to be silent in stem/progenitor cells yet can be readily activate... Read more »

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Microplex Library Preparation kit

Events

  • Epigenetic Mechanisms in Health and Disease 2017
    Barcelona, Spain
    Oct 25-Oct 26, 2017
  • 35ème Congrès de la Societé Française de Toxicologie Génétique
    Marseille, France
    Oct 26-Oct 27, 2017
  • 7th Australian Epigenetics Conference
    Brisbane, Australia
    Oct 29-Nov 1, 2017
  • Australian Genomic Technologies Association (AGTA 2017 Annual Conference)
    Hobart, Tasmania
    Oct 29-Nov 1, 2017
 See all events

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