Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain o...
Published: January, 2018

Abstract: Sirtuins are NAD+-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulate... Read more »
A novel long noncoding RNA LINC00844 regulates prostate cancer cell...
Published: January, 2018

Abstract: The majority of the human genome is transcribed, yielding a rich repository of non-coding transcripts that are involved in a myriad of biological p... Read more »

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Bioruptor
APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC ...
Published: January, 2018

Abstract: To date, epimutations reported in man have been somatic and erased in germlines. Here, we identify a cause of the autosomal recessive cblC class of... Read more »

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IP-Star Histone ChIP kit
Copper induces expression and methylation changes of early developm...
Published: January, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit
TBR2 antagonizes retinoic acid dependent neuronal differentiation b...
Published: January, 2018

Abstract: During cerebral cortex development, neural progenitors are required to elaborate a variety of cell differentiation signals to which they are contin... Read more »
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: December, 2017

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Bioruptor ChIP-seq
Dual SIRT1 expression patterns strongly suggests its bivalent role ...
Published: December, 2017

Abstract: Breast cancer is the most common cancer in women, and the leading cause of cancer death in women worldwide. SIRT1 (silent mating type information r... Read more »

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Antibody
Super enhancer associated RAI14 is a new potential biomarker in lun...
Published: December, 2017

Abstract: Tyrosine kinase inhibitors (TKIs) are widely used to treat lung adenocarcinoma patients with EGFR mutations or ALK-fusions. However, patients with ... Read more »

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Bioruptor
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesen...
Published: November, 2017

Abstract: RATIONALE: Human cardiac mesenchymal cells (CMSCs) are a therapeutically relevant primary cell population. Diabetes mellitus compromises CMSC fu... Read more »
FBXO32 promotes microenvironment underlying epithelial-mesenchymal ...
Published: November, 2017

Abstract: The set of events that convert adherent epithelial cells into migratory cells are collectively known as epithelial-mesenchymal transition (EMT). EM... Read more »

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Antibody
GATA2/3-TFAP2A/C transcription factor network couples human pluripo...
Published: November, 2017

Abstract: To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophectoderm character... Read more »

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Antibody
5-Methylcytosine RNA Methylation in Arabidopsis Thaliana
Published: November, 2017

Abstract: 5-Methylcytosine (m5C) is a well-characterized DNA modification, and is also predominantly reported in abundant non-coding RNAs in both prokaryotes... Read more »

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Antibody
An endosiRNA-Based Repression Mechanism Counteracts Transposon Acti...
Published: November, 2017

Abstract: Erasure of DNA methylation and repressive chromatin marks in the mammalian germline leads to risk of transcriptional activation of transposable ele... Read more »

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Microplex Library Preparation kit
Transcription Factor YY1 Modulates Lung Cancer Progression by Activ...
Published: November, 2017

Abstract: Lung cancer is the leading cause of cancer-related death worldwide. Despite the advancement in surgery and chemotherapy, the prognosis of patients ... Read more »
Epigenetic control of epilepsy target genes contributes to a cellul...
Published: October, 2017

Abstract: Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable l... Read more »
Drug-tunable multidimensional synthetic gene control using inducibl...
Published: October, 2017

Abstract: The nuclease-deactivated variant of CRISPR-Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA sequen... Read more »

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Antibody
Saliva as a Blood Alternative for Genome-Wide DNA Methylation Profi...
Published: October, 2017

Abstract: Background: Interrogation of DNA methylation profiles hold promise for improved diagnostics, as well as the delineation of the aetiology for common... Read more »

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IP-Star Compact
Alterations in the placental methylome with maternal obesity and ev...
Published: October, 2017

Abstract: The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complicat... Read more »

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Antibody
Single-Molecule Sequencing Reveals the Chromosome-Scale Genomic Arc...
Published: October, 2017

Abstract: The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegan... Read more »

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Megaruptor
Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valpr...
Published: October, 2017

Abstract: Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs in the world. Despite its pharmacological importance, it may cause liv... Read more »

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MagMeDIP kit IPure kit
Individual effects of the copia and gypsy enhancer and insulator on...
Published: October, 2017

Abstract: Enhancers and insulators are involved in the regulation of gene expression, but the basic underlying mechanisms of action of these elements are unk... Read more »

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ChIP-qPCR
Distinguishing States of Arrest: Genome-Wide Descriptions of Cellul...
Published: October, 2017

Abstract: Regenerative potential in adult stem cells is closely associated with the establishment of-and exit from-a temporary state of quiescence. Emerging ... Read more »

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LowCell ChIP kit IPure kit
Genome methylation and regulatory functions for hypoxic adaptation...
Published: October, 2017

Abstract: Tibetan chickens have unique adaptations to the extreme high-altitude environment that they inhabit. Epigenetic DNA methylation affects many biolog... Read more »

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MagMeDIP kit
The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and...
Published: October, 2017

Abstract: Genomic imprinting is an allelic gene expression phenomenon primarily controlled by allele-specific DNA methylation at the imprinting control regio... Read more »

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Antibody
The mixed lineage leukemia 4 (MLL4) methyltransferase complex is in...
Published: October, 2017

Abstract: Sma and Mad related (SMAD)-mediated Transforming Growth Factor β (TGF-β) and Bone Morphogenetic Protein (BMP) signaling is required for v... Read more »

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Antibody
De novo PacBio long-read and phased avian genome assemblies correct...
Published: October, 2017

Abstract: Reference-quality genomes are expected to provide a resource for studying gene structure, function, and evolution. However, often genes of interest... Read more »

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Megaruptor
BET-bromodomain inhibitors modulate epigenetic patterns at the diac...
Published: October, 2017

Abstract: BACKGROUND AND PURPOSE: Fibrosis is a frequent adverse effect of radiotherapy and no effective treatments are currently available to prevent or re... Read more »

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IP-Star Compact
Rapid Communication: The correlation between histone modifications ...
Published: October, 2017

Abstract: Histone modification is a well-known epigenetic mechanism involved in regulation of gene expression; however, it has been poorly studied in adipose... Read more »

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Antibody LowCell ChIP kit
TET2- and TDG-mediated changes are required for the acquisition of ...
Published: September, 2017

Abstract: The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MAC... Read more »

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Antibody LowCell ChIP kit
Genomic imprinting of Xist by maternal H3K27me3
Published: September, 2017

Abstract: Maternal imprinting at the Xist gene is essential to achieve paternal allele-specific imprinted X-chromosome inactivation (XCI) in female mammals. ... Read more »

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H3K27me3 (C15410069)

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