Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Improved reference genome of Aedes aegypti informs arbovirus vector...
Published: November, 2018

Abstract: Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika a... Read more »
Sensitive tumour detection and classification using plasma cell-fre...
Published: November, 2018

Abstract: The use of liquid biopsies for cancer detection and management is rapidly gaining prominence. Current methods for the detection of circulating tumo... Read more »
Whole-genome landscape of Medicago truncatula symbiotic genes.
Published: November, 2018

Abstract: Advances in deciphering the functional architecture of eukaryotic genomes have been facilitated by recent breakthroughs in sequencing technologies,... Read more »
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to...
Published: November, 2018

Abstract: Here, we report DNA methylation and hydroxymethylation dynamics at nucleotide resolution using C/EBPα-enhanced reprogramming of B cells into induce... Read more »
Oxidative stress in sperm affects the epigenetic reprogramming in e...
Published: October, 2018

Abstract: BACKGROUND: Reactive oxygen species (ROS)-induced oxidative stress is well known to play a major role in male infertility. Sperm are sensitive to R... Read more »

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Antibody
Long-read sequence capture of the hemoglobin gene clusters across g...
Published: October, 2018

Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »
SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a ...
Published: October, 2018

Abstract: Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disea... Read more »
Demethylation of ITGAV accelerates osteogenic differentiation in a ...
Published: October, 2018

Abstract: Trauma-induced heterotopic ossification is an intriguing phenomenon involving the inappropriate ossification of soft tissues within the body such a... Read more »
ΔNp63-driven recruitment of myeloid-derived suppressor cells promot...
Published: October, 2018

Abstract: Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastas... Read more »

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ChIP-seq
Directional high-throughput sequencing of RNAs without gene-specifi...
Published: October, 2018

Abstract: Ribosomal RNA analysis is a useful tool for characterization of microbial communities. However, the lack of broad-range primers has hampered the si... Read more »
SOX4 inhibits oligodendrocyte differentiation of embryonic neural s...
Published: October, 2018

Abstract: SOX4 has been shown to promote neuronal differentiation both in the adult and embryonic neural progenitors. Ectopic SOX4 expression has also been s... Read more »

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Antibody
Cellular localization of the cell cycle inhibitor Cdkn1c controls g...
Published: October, 2018

Abstract: Adult skeletal muscle maintenance and regeneration depend on efficient muscle stem cell (MuSC) functions. The mechanisms coordinating cell cycle wi... Read more »

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Antibody
Integrated analysis of DNA methylation profiling and gene expressio...
Published: October, 2018

Abstract: BACKGROUND: Aberrant DNA methylation occurs frequently in cancer. The aim of this study was to identify novel methylation markers in lung cancer in... Read more »

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Antibody
Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Choles...
Published: October, 2018

Abstract: The mechanisms underlying sterol transport in mammalian cells are poorly understood. In particular, how cholesterol internalized from HDL is made a... Read more »
Genomic Structural Variations Within Five Continental Populations of .
Published: October, 2018

Abstract: Chromosomal structural variations (SV) including insertions, deletions, inversions, and translocations occur within the genome and can have a signi... Read more »

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Megaruptor
Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy du...
Published: October, 2018

Abstract: NF-E2-related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidat... Read more »

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Antibody
Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone ...
Published: October, 2018

Abstract: Proteomic analysis of histones has shown that they are subject to a superabundance of acylations, which extend far beyond acetylation, to include: ... Read more »

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IPure kit
The Itaconate Pathway Is a Central Regulatory Node Linking Innate I...
Published: October, 2018

Abstract: Sepsis involves simultaneous hyperactivation of the immune system and immune paralysis, leading to both organ dysfunction and increased susceptibil... Read more »

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Antibody Bioruptor Plus
Long-read sequencing identified a causal structural variant in an e...
Published: September, 2018

Abstract: Background: For a proportion of individuals judged clinically to have a recessive Mendelian disease, only one heterozygous pathogenic variant can b... Read more »

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Megaruptor
Gap junction protein Connexin-43 is a direct transcriptional regula...
Published: September, 2018

Abstract: Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes. Here, we demonstrat... Read more »
Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting...
Published: September, 2018

Abstract: How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E... Read more »
Impact of human sepsis on CCCTC-binding factor associated monocyte ...
Published: September, 2018

Abstract: BACKGROUND: Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for... Read more »

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Antibody
The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidi...
Published: September, 2018

Abstract: Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues... Read more »
The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidi...
Published: September, 2018

Abstract: Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues... Read more »
NGS analysis of total small non coding RNAs from low input RNA from...
Published: September, 2018

Abstract: Circulating miRNAs are favored for biomarker candidates as they can reflect tissue specific miRNA dysregulation in disease contexts. Moreover, they... Read more »
FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis e...
Published: September, 2018

Abstract: The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In ... Read more »

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ChIP-seq
Dot1 promotes H2B ubiquitination by a methyltransferase-independent...
Published: September, 2018

Abstract: The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H... Read more »
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purki...
Published: September, 2018

Abstract: In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of sy... Read more »
Differential DNA methylation of potassium channel KCa3.1 and immune...
Published: August, 2018

Abstract: Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary disease ... Read more »
Polycomb repressive complex 1 shapes the nucleosome landscape but n...
Published: August, 2018

Abstract: Polycomb group (PcG) proteins are transcriptional repressors that play important roles in regulating gene expression during animal development. In ... Read more »

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Antibody

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