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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

SUMO protease FUG1, histone reader AL3 and the PRC1 Complex areinte...
Published: December, 2023
Abstract: Epigenetic gene silencing induced by expanded repeats can cause diverse phenotypes ranging from severe growth defects in plants to genetic diseases... Read more »
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Pre-diagnosis plasma cell-free DNA methylome profiling up to seven ...
Published: February, 2023
Abstract: Profiling of cell-free DNA (cfDNA) has been well demonstrated to be a potential non-invasive screening tool for early cancer detection. However, li... Read more »
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Cell-free multi-omics analysis reveals tumor status-informative sig...
Published: February, 2023
Abstract: During cancer development, host’s tumorigenesis and immune signals are released to and informed by circulating molecules, like cell-free DNA (cfDNA... Read more »
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Low affinity CTCF binding drives transcriptional regulation whereas...
Published: February, 2023
Abstract: CTCF is a DNA-binding protein which plays critical roles in chromatin structure organization and transcriptional regulation; however, little is kno... Read more »
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Draft genome assemblies of the avian louse Brueelia nebulosa and it...
Published: February, 2023
Abstract: Sequencing high molecular weight (HMW) DNA with long-read and linked-read technologies has promoted a major increase in more complete genome sequen... Read more »
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Targeting high glucose-induced epigenetic modifications at cardiac ...
Published: February, 2023
Abstract: BACKGROUND: Sodium-glucose co-transporters (SGLT) inhibitors (SGLT2i) showed many beneficial effects at the cardiovascular level. Several mechanism... Read more »
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Myelodysplastic Syndrome associated TET2 mutations affect NK cell f...
Published: February, 2023
Abstract: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders, representing high risk of progression to acute myeloid leukaemia, and frequentl... Read more »
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Species-specific regulation of XIST by the JPX/FTX orthologs.
Published: February, 2023
Abstract: X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main tr... Read more »
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Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42...
Published: February, 2023
Abstract: Reduced insulin-like growth factor 2 (IGF2) levels in Alzheimer's disease (AD) may be the mechanism relating age-related metabolic disorders to dem... Read more »
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The genome sequence of the Grey Ermine, Yponomeuta sedella (Treitsc...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Yponomeuta sedella (the Grey Ermine; Arthropoda; Insecta; Lepidoptera; Yponomeutidae). The gen... Read more »
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The genome sequence of the Mouse Moth, Amphipyra tragopoginis (Cler...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Amphipyra tragopoginis (the Mouse Moth; Arthropoda; Insecta; Lepidoptera; Noctuidae). The geno... Read more »
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The genome sequence of the Miller, Acronicta leporina (Linnaeus, 1758)
Published: February, 2023
Abstract: We present a genome assembly from an individual female Acronicta leporina (the Miller; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome seq... Read more »
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The genome sequence of a soldier beetle, Podabrus alpinus (Paykull,...
Published: February, 2023
Abstract: We present a genome assembly from an individual female Podabrus alpinus (soldier beetle; Arthropoda; Insecta; Coleoptera; Cantharidae). The genome ... Read more »
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The genome sequence of a beetle-killing wasp, Tiphia femorata (Fabr...
Published: February, 2023
Abstract: We present a genome assembly from an individual female Tiphia femorata (a beetle-killing wasp; Arthropoda; Insecta; Hymenoptera; Tiphilidae). The g... Read more »
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The genome sequence of the Green-brindled Crescent, Allophyes oxyac...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Allophyes oxyacanthae (the Green-brindled Crescent; Arthropoda; Insecta; Lepidoptera; Noctuida... Read more »
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The genome sequence of the Rustic Shoulder-knot, Apamea sordens (Hu...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Apamea sordens (the Rustic Shoulder-knot; Arthropoda; Insecta; Lepidoptera; Noctuidae). The ge... Read more »
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The genome sequence of the Elbow-stripe Grass-veneer, Agriphilageni...
Published: February, 2023
Abstract: We present a genome assembly from an individual female Agriphila geniculea (the Elbow-stripe Grass-veneer; Arthropoda; Insecta; Lepidoptera; Crambi... Read more »
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The genome sequence of the Turnip Sawfly, Athalia rosae(Linnaeus, 1...
Published: February, 2023
Abstract: We present a genome assembly from an individual female Athalia rosae (the Turnip Sawfly; Arhropoda; Insecta; Hymenoptera; Athaliidae). The genome s... Read more »
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Megaruptor
The genome sequence of a tachinid fly, Thecocarcelia acutangulata (...
Published: February, 2023
Abstract: We present a genome assembly from an individual female Thecocarcelia acutangulata (a tachinid fly; Arthropoda; Insecta; Diptera; Tachinidae). The g... Read more »
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Single-strand mismatch and damage patterns revealed by single-molec...
Published: February, 2023
Abstract: Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other genetic diseases . Almost all of these mosa... Read more »
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Detailed molecular and epigenetic characterization of the Pig IPECJ...
Published: February, 2023
Abstract: The pig IPECJ2 and chicken SL-29 cell lines are of interest because of their untransformed nature and wide use in functional studies. Molecular cha... Read more »
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Cotranscriptional demethylation induces global loss of H3K4me2 from...
Published: February, 2023
Abstract: Based on studies of animals and yeasts, methylation of histone H3 lysine 4 (H3K4me1/2/3, for mono-, di-, and tri-methylation, respectively) is rega... Read more »
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Histone remodeling reflects conserved mechanisms of bovine and huma...
Published: February, 2023
Abstract: How histone modifications regulate changes in gene expression during preimplantation development in any species remains poorly understood. Using CU... Read more »
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Epigenetic regulation of plastin 3 expression by the macrosatellite...
Published: February, 2023
Abstract: Dysregulated Plastin 3 (PLS3) levels associate with a wide range of skeletal and neuromuscular disorders and the most common types of solid and hem... Read more »
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The Hdc GC box is critical for Hdc gene transcription and histamine...
Published: February, 2023
Abstract: BACKGROUND: Histamine is a critical mediator of anaphylaxis, a neurotransmitter, and a regulator of gastric acid secretion. Histidine decarboxylase... Read more »
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A dataset of definitive endoderm and hepatocyte differentiations fr...
Published: February, 2023
Abstract: Hepatocytes are a major parenchymal cell type in the liver and play an essential role in liver function. Hepatocyte-like cells can be differentiate... Read more »
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Signal-induced enhancer activation requires Ku70 to read topoisomer...
Published: February, 2023
Abstract: Enhancer activation serves as the main mechanism regulating signal-dependent transcriptional programs, ensuring cellular plasticity, yet central qu... Read more »
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Methylation and expression of glucocorticoid receptor exon-1 varian...
Published: February, 2023
Abstract: A dysregulated hypothalamic-pituitary-adrenal (HPA) axis has repeatedly been demonstrated to play a fundamental role in psychiatric disorders and s... Read more »
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Bridging biological cfDNA features and machine learning approaches.
Published: February, 2023
Abstract: Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to revolutionize precision oncology and blood-based cancer sc... Read more »
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Characterization of De Novo Promoter Variants in Autism Spectrum Di...
Published: February, 2023
Abstract: Autism spectrum disorder (ASD) is a common, complex, and highly heritable condition with contributions from both common and rare genetic variations... Read more »
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