Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018

Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »

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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Functional interplay between E2F7 and ribosomal rRNA gene transcrip...
Published: May, 2018

Abstract: A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. ... Read more »

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Bioruptor
Local adaptation and ecological differentiation under selection, mi...
Published: May, 2018

Abstract: How the balance between selection, migration and drift influences the evolution of local adaptation has been under intense theoretical scrutiny. Ye... Read more »

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Bioruptor
The chromatin remodeling factor SPOC1 acts as a cellular restricti...
Published: May, 2018

Abstract: The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA dam... Read more »

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Bioruptor Bioruptor Plus
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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ChIP-seq
Nuclear fate of yeast snoRNA is determined by co-transcriptional Rn...
Published: May, 2018

Abstract: Small nucleolar RNA (snoRNA) are conserved and essential non-coding RNA that are transcribed by RNA Polymerase II (Pol II). Two snoRNA classes, for... Read more »

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Bioruptor
SUN2 Modulates HIV-1 Infection and Latency through Association with...
Published: May, 2018

Abstract: The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV gen... Read more »

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Bioruptor
Viral targeting of TFIIB impairs de novo polymerase II recruitment ...
Published: April, 2018

Abstract: Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regula... Read more »

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Bioruptor Bioruptor Plus
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: April, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Bioruptor Bioruptor Plus
Generation of a PAX6 knockout glioblastoma cell line with changes i...
Published: April, 2018

Abstract: The transcription factor PAX6 is expressed in various cancers. In anaplastic astrocytic glioma, PAX6 expression is inversely related to tumor gra... Read more »

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Bioruptor Bioruptor Plus
MYCN acts as a direct co-regulator of p53 in MYCN amplified neurobl...
Published: April, 2018

Abstract: The MYC oncogenes and p53 have opposing yet interrelated roles in normal development and tumorigenesis. How MYCN expression alters the biology and ... Read more »

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Bioruptor
Phylogenomic evidence for a recent and rapid radiation of lizards i...
Published: March, 2018

Abstract: Rapid evolutionary radiations are difficult to resolve because divergence events are nearly synchronous and gene flow among nascent species can be ... Read more »
Application of next-generation sequencing to characterize novel mut...
Published: March, 2018

Abstract: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of H. pylori eradication. Although the molecular me... Read more »
Effects of developmental lead exposure on the hippocampal methylome...
Published: March, 2018

Abstract: Developmental lead (Pb) exposure results in persistent cognitive/behavioral impairments as well as an elevated risk for developing a variety of dis... Read more »

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IP-Star Compact
Analysis of Meiotic Double-Strand Break Initiation in Mammals
Published: March, 2018

Abstract: The repair of programmed DNA double-strand breaks (DSBs) physically tethers homologous chromosomes in meiosis t... Read more »

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Bioruptor
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

Tags
ChIP-seq
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

Tags
ChIP-seq
zHSF1 modulates zper2 expression in zebrafish embryos
Published: March, 2018

Abstract: HSF1 is a transcription factor that plays a key role in circadian resetting by temperature. We have used zebrafish embryos to decipher the roles of... Read more »
CRL7SMU1 E3 ligase complex driven H2B ubiquitination functions in s...
Published: March, 2018

Abstract: Cullin–RING E3 ligases (CRLs) control broad range of biological processes by ubiquitinating numerous cellular substrates. However, role of CR... Read more »
Differential α-synuclein expression contributes to selective vulner...
Published: March, 2018

Abstract: The accumulation of misfolded α-synuclein (aSyn) and neuron loss define several neurodegenerative disorders including Parkinson’s disea... Read more »
Lyar-mediated recruitment of Brd2 to the chromatin attenuates Nanog...
Published: March, 2018

Abstract: During development, cellular differentiation programs need of tight regulation for proper display of the activity of multiple factors in time and s... Read more »

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Bioruptor
The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018

Abstract: Cytotoxic CD4 (CD4CTX) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their develop... Read more »

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H3pan (C15310135)
β1-integrin impacts Rad51 stability and DNA double-strand break rep...
Published: February, 2018

Abstract: The molecular mechanisms underlying resistance to radiotherapy in breast cancer cells remain elusive. Previously, we reported that elevated &beta... Read more »
TGFβ signaling hyperactivation-induced tumorigenicity during the de...
Published: February, 2018

Abstract: Clinical therapies of pluripotent stem cells (PSCs)-based transplantation have been hindered by frequent development of teratomas or tumors in anim... Read more »
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: February, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora ... Read more »

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ChIP-seq
MAX to MYCN intracellular ratio drives the aggressive phenotype and...
Published: February, 2018

Abstract: Childhood neuroblastoma, a disease of the sympathetic nervous system, is the most common solid tumour of infancy, remarkably refractory to therapeu... Read more »
Micro-ribonucleic acid-155 is a direct target of Meis1, but not a d...
Published: February, 2018

Abstract: Micro-ribonucleic acid-155 (miR-155) is one of the first described oncogenic miRNAs. Although multiple direct targets of miR-155 have been identifi... Read more »

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Antibody
Widespread bacterial protein histidine phosphorylation revealed by ...
Published: January, 2018

Abstract: For decades, major difficulties in analyzing histidine phosphorylation have limited the study of phosphohistidine signaling. Here we report a metho... Read more »

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Bioruptor Plus
Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase K...
Published: January, 2018

Abstract: Schwann cell differentiation and myelination depends on chromatin remodeling, histone acetylation, and methylation, which all affect Schwann cell p... Read more »

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Antibody
Integrative omics data analyses of repeated dose toxicity of valpro...
Published: January, 2018

Abstract: Valproic acid (VPA) is a very potent anti-cancer and neuro-protective drug probably by its HDAC inhibiting properties, which may cause steatosis in... Read more »

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MagMeDIP kit

Events

  • The 12th Annual Meeting of the Japanese Society for Epigenetics
    Jun 24-Jun 25, 2018
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Applications

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