Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

DNA methylation of the Tacr2 gene in a CUMS model of depression.
Published: June, 2019

Abstract: Tacr2, the gene encoding the NK2 receptor, belongs to G protein-coupled receptors. Accumulating evidence has indicated that the tachykinin receptor... Read more »

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MagMeDIP kit
Genome Sequence and Methylation Patterns of sp. Strain BOL3-1, the...
Published: May, 2019

Abstract: sp. strain BOL3-1 was isolated from Salar de Uyuni, Bolivia, and sequenced using single-molecule real-time sequencing. Its 3.7-Mbp genome was analy... Read more »

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Megaruptor
Guidelines for optimized gene knockout using CRISPR/Cas9
Published: May, 2019

Abstract: CRISPR/Cas9 technology has evolved as the most powerful approach to generate genetic models both for fundamental and preclinical research. Despite ... Read more »

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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors CRISPR
Assessment and site-specific manipulation of DNA (hydroxy-)methylat...
Published: April, 2019

Abstract: Dynamic changes in DNA (hydroxy-)methylation are fundamental for stem cell differentiation. However, the signature of these epigenetic marks in spe... Read more »

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MagMeDIP kit
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human ...
Published: March, 2019

Abstract: Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcripti... Read more »

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Antibody
Restriction-site associated DNA sequencing supports a sister group ...
Published: March, 2019

Abstract: The orchid genus Nigritella is closely related to Gymnadenia and has from time to time been merged with the latter. Although Nigritella is morpholo... Read more »
Biocompatible N-acetyl cysteine reduces graphene oxide and persists...
Published: March, 2019

Abstract: We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced ... Read more »

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Megaruptor
Point mutations in the PDX1 transactivation domain impair human β-c...
Published: March, 2019

Abstract: OBJECTIVE: Hundreds of missense mutations in the coding region of PDX1 exist; however, if these mutations predispose to diabetes mellitus is unknow... Read more »

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Antibody Microplex Library Preparation kit
H3K27M induces defective chromatin spread of PRC2-mediated repressi...
Published: March, 2019

Abstract: Lys-27-Met mutations in histone 3 genes (H3K27M) characterize a subgroup of deadly gliomas and decrease genome-wide H3K27 trimethylation. Here we u... Read more »

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IP-Star Compact iDeal ChIP-seq Kit for Histones
Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in ...
Published: March, 2019

Abstract: Developing and adult tissues use different cis-regulatory elements. Although DNA at some decommissioned embryonic enhancers is hypomethylated in ad... Read more »

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Antibody
DMSO induces drastic changes in human cellular processes and epigen...
Published: March, 2019

Abstract: Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity in the 1960s, later, the FDA classified DMSO in the ... Read more »

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MagMeDIP kit
The role of TCF3 as potential master regulator in blastemal Wilms t...
Published: March, 2019

Abstract: Wilms tumors are the most common type of pediatric kidney tumors. While the overall prognosis for patients is favorable, especially tumors that exh... Read more »

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Antibody
R-Loops Enhance Polycomb Repression at a Subset of Developmental Re...
Published: March, 2019

Abstract: R-loops are three-stranded nucleic acid structures that form during transcription, especially over unmethylated CpG-rich promoters of active genes.... Read more »

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Antibody
Genetic, Inflammatory, and Epithelial Cell Differentiation Factors ...
Published: March, 2019

Abstract: Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that... Read more »

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IP-Star Compact
The epigenetic basis for the impaired ability of adult murine retin...
Published: March, 2019

Abstract: The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenerate the entire retina, a trait known to be absent in ... Read more »

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Antibody IP-Star Compact True MicroChIP kit
MicroRNAs and Transplantation.
Published: March, 2019

Abstract: miRNAs, ∼20 to 22 nucleotide single-stranded RNA species that play a pivotal role in the regulation of protein-coding genes, are emerging as ro... Read more »

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CATS
Differential regulation of RNA polymerase III genes during liver re...
Published: February, 2019

Abstract: Mouse liver regeneration after partial hepatectomy involves cells in the remaining tissue synchronously entering the cell division cycle. We have u... Read more »

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Microplex Library Preparation kit
EZH2 is overexpressed in transitional preplasmablasts and is involv...
Published: February, 2019

Abstract: Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using m... Read more »

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Antibody IPure kit IP-Star Compact True MicroChIP kit iDeal ChIP-seq Kit for Transcription Factors
Crosstalk Between Glucocorticoid Receptor and Early-growth Response...
Published: February, 2019

Abstract: The brain-derived neurotrophic factor (BDNF) is a key player in brain functions such as synaptic plasticity, stress, and behavior. Its gene structu... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Characterizing the Major Structural Variant Alleles of the Human Ge...
Published: January, 2019

Abstract: In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen... Read more »

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Megaruptor
Complete Genome Sequence and Methylome Analysis of Micrococcus lute...
Published: January, 2019

Abstract: Micrococcus luteus has been found in a wide range of habitats. We report the complete genome sequence and methylome analysis of strain SA211 isolat... Read more »

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Megaruptor
CRISPR-mediated activation of a promoter or enhancer rescues obesit...
Published: January, 2019

Abstract: A wide range of human diseases result from haploinsufficiency, where the function of one of the two gene copies is lost. Here, we targeted the rema... Read more »

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CRISPR
High-throughput ChIPmentation: freely scalable, single day ChIPseq ...
Published: January, 2019

Abstract: BACKGROUND: Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor bin... Read more »

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Antibody
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Ep...
Published: January, 2019

Abstract: CD4 T helper (Th) differentiation is regulated by diverse inputs, including the vitamin A metabolite retinoic acid (RA). RA acts through its recept... Read more »

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Antibody
Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rha...
Published: January, 2019

Abstract: Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin remodeling complex, is the hallmark genetic aberration of atypical te... Read more »

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Antibody
Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Pro...
Published: January, 2019

Abstract: Adenosine deaminase associated with RNA1 (ADAR1) deregulation contributes to therapeutic resistance in many malignancies. Here we show that ADAR1-i... Read more »

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Antibody LowCell ChIP kit
Fluorescence-Activated Cell Sorting-Based Isolation and Characteriz...
Published: January, 2019

Abstract: Adult mammalian brain, including humans, has rather limited addition of new neurons and poor regenerative capacity. In contrast, neural stem cells ... Read more »

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Microplex Library Preparation kit
The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and...
Published: January, 2019

Abstract: We identified a regulatory system that acts downstream of Wnt/β-catenin signaling in salivary gland and head and neck carcinomas. We show in a... Read more »

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Antibody iDeal ChIP-seq Kit for Histones iDeal Library Preparation Kit
LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA...
Published: January, 2019

Abstract: Long non-coding RNAs (lncRNAs) play key roles in various biological processes. However, the roles of lncRNAs in macrophage polarization remain larg... Read more »

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MagMeDIP kit
The histone methyltransferase DOT1L is required for proper DNA dama...
Published: January, 2019

Abstract: BACKGROUND: Disruptor of telomeric silencing 1-like (DOT1L) is a non-SET domain containing methyltransferase known to catalyze mono-, di-, and tri-... Read more »

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Antibody

Events

  • European Human Genetics Conference
    Gothenburg, Sweden
    Jun 15-Jun 18, 2019
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