Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Analysis of Meiotic Double-Strand Break Initiation in Mammals
Published: March, 2018

Abstract: The repair of programmed DNA double-strand breaks (DSBs) physically tethers homologous chromosomes in meiosis t... Read more »

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Bioruptor
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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ChIP-seq
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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ChIP-seq
zHSF1 modulates zper2 expression in zebrafish embryos
Published: March, 2018

Abstract: HSF1 is a transcription factor that plays a key role in circadian resetting by temperature. We have used zebrafish embryos to decipher the roles of... Read more »

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CRISPR
CRL7SMU1 E3 ligase complex driven H2B ubiquitination functions in s...
Published: March, 2018

Abstract: Cullin–RING E3 ligases (CRLs) control broad range of biological processes by ubiquitinating numerous cellular substrates. However, role of CR... Read more »
Differential α-synuclein expression contributes to selective vulner...
Published: March, 2018

Abstract: The accumulation of misfolded α-synuclein (aSyn) and neuron loss define several neurodegenerative disorders including Parkinson’s disea... Read more »
Lyar-mediated recruitment of Brd2 to the chromatin attenuates Nanog...
Published: March, 2018

Abstract: During development, cellular differentiation programs need of tight regulation for proper display of the activity of multiple factors in time and s... Read more »

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Bioruptor
Copper induces expression and methylation changes of early developm...
Published: March, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit Antibody
The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018

Abstract: Cytotoxic CD4 (CD4CTX) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their develop... Read more »

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H3pan (C15310135)
β1-integrin impacts Rad51 stability and DNA double-strand break rep...
Published: February, 2018

Abstract: The molecular mechanisms underlying resistance to radiotherapy in breast cancer cells remain elusive. Previously, we reported that elevated &beta... Read more »
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: February, 2018

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Antibody
TGFβ signaling hyperactivation-induced tumorigenicity during the de...
Published: February, 2018

Abstract: Clinical therapies of pluripotent stem cells (PSCs)-based transplantation have been hindered by frequent development of teratomas or tumors in anim... Read more »
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: February, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora ... Read more »

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ChIP-seq
MAX to MYCN intracellular ratio drives the aggressive phenotype and...
Published: February, 2018

Abstract: Childhood neuroblastoma, a disease of the sympathetic nervous system, is the most common solid tumour of infancy, remarkably refractory to therapeu... Read more »
Micro-ribonucleic acid-155 is a direct target of Meis1, but not a d...
Published: February, 2018

Abstract: Micro-ribonucleic acid-155 (miR-155) is one of the first described oncogenic miRNAs. Although multiple direct targets of miR-155 have been identifi... Read more »

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Antibody
Widespread bacterial protein histidine phosphorylation revealed by ...
Published: January, 2018

Abstract: For decades, major difficulties in analyzing histidine phosphorylation have limited the study of phosphohistidine signaling. Here we report a metho... Read more »

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Bioruptor Plus
Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase K...
Published: January, 2018

Abstract: Schwann cell differentiation and myelination depends on chromatin remodeling, histone acetylation, and methylation, which all affect Schwann cell p... Read more »

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Antibody
Integrative omics data analyses of repeated dose toxicity of valpro...
Published: January, 2018

Abstract: Valproic acid (VPA) is a very potent anti-cancer and neuro-protective drug probably by its HDAC inhibiting properties, which may cause steatosis in... Read more »

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MagMeDIP kit
BCG Vaccination Protects against Experimental Viral Infection in Hu...
Published: January, 2018

Abstract: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) has heterologous beneficial effects against non-related infections. The basis of the... Read more »

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Antibody
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain o...
Published: January, 2018

Abstract: Sirtuins are NAD+-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulate... Read more »
A novel long noncoding RNA LINC00844 regulates prostate cancer cell...
Published: January, 2018

Abstract: The majority of the human genome is transcribed, yielding a rich repository of non-coding transcripts that are involved in a myriad of biological p... Read more »

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Bioruptor
APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC ...
Published: January, 2018

Abstract: To date, epimutations reported in man have been somatic and erased in germlines. Here, we identify a cause of the autosomal recessive cblC class of... Read more »

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IP-Star Histone ChIP kit
Copper induces expression and methylation changes of early developm...
Published: January, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit
STAT5BN642H is a driver mutation for T cell neoplasia
Published: January, 2018

Abstract: STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and... Read more »

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Antibody
Genome-wide analysis of day/night DNA methylation differences in Po...
Published: January, 2018

Abstract: DNA methylation is an important mechanism of epigenetic modification. Methylation changes during stress responses and developmental processes have ... Read more »

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MagMeDIP kit Antibody
Obligatory and facilitative allelic variation in the DNA methylome ...
Published: January, 2018

Abstract: Integrating epigenetic data with genome-wide association study (GWAS) results can reveal disease mechanisms. The genome sequence itself also&n... Read more »

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MagMeDIP kit Antibody
MLL2 conveys transcription-independent H3K4 trimethylation in oocytes
Published: January, 2018

Abstract: Histone 3 K4 trimethylation (depositing H3K4me3 marks) is typically associated with active promoters yet paradoxically occurs at untranscribed doma... Read more »

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Antibody Microplex Library Preparation kit
TBR2 antagonizes retinoic acid dependent neuronal differentiation b...
Published: January, 2018

Abstract: During cerebral cortex development, neural progenitors are required to elaborate a variety of cell differentiation signals to which they are contin... Read more »
Chromatin Immunoprecipitation Assay in the Hyperthermoacidophilic C...
Published: January, 2018

Abstract: Chromatin immunoprecipitation (ChIP) is a powerful method used for identifying genome-wide DNA-protein interactions in vivo. A large number of esse... Read more »

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IPure kit
Antioxydation And Cell Migration Genes Are Identified as Potential ...
Published: January, 2018

Abstract: Basal-like breast cancers are among the most aggressive cancers and effective targeted therapies are still missing. In order to identify new therap... Read more »

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MethylCap

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