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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Revisiting promyelocytic leukemia protein targeting by human cytome...
Published: May, 2020

Abstract: Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, centra... Read more »

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Antibody
In vitro capture and characterization of embryonic rosette-stage pl...
Published: May, 2020

Abstract: Following implantation, the naive pluripotent epiblast of the mouse blastocyst generates a rosette, undergoes lumenogenesis and forms the primed pl... Read more »

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Antibody
The domesticated transposase ALP2 mediates formation of a novel Pol...
Published: May, 2020

Abstract: A large fraction of plant genomes is composed of transposable elements (TE), which provide a potential source of novel genes through "domestication... Read more »

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Antibody
Genomic Profiling by ALaP-Seq Reveals Transcriptional Regulation by...
Published: April, 2020

Abstract: The promyelocytic leukemia (PML) body is a phase-separated nuclear structure physically associated with chromatin, implying its crucial roles in ge... Read more »

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Antibody
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloi...
Published: April, 2020

Abstract: Tissue-resident and recruited macrophages contribute to both host defense and pathology. Multiple macrophage phenotypes are represented in diseased... Read more »

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Antibody
SETDB2 promoted breast cancer stem cell maintenance by interaction ...
Published: April, 2020

Abstract: The histone H3K9 methyltransferase SETDB2 is involved in cell cycle dysregulation in acute leukemia and has oncogenic roles in gastric cancer. In o... Read more »

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Antibody
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments ...
Published: April, 2020

Abstract: Long non-coding RNAs (lncRNAs) contribute to cardiac (patho)physiology. Aging is the major risk factor for cardiovascular disease with cardiomyocyt... Read more »

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Antibody Beads
UNBRANCHED3 Expression and Inflorescence Development is Mediated by...
Published: April, 2020

Abstract: Enhancers are cis-acting DNA segments with the ability to increase target gene expression. They show high sensitivity to DNase and contain specific... Read more »

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IPure kit Beads
Non-coding somatic mutations converge on the PAX8 pathway in ovaria...
Published: April, 2020

Abstract: The functional consequences of somatic non-coding mutations in ovarian cancer (OC) are unknown. To identify regulatory elements (RE) and genes pert... Read more »

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Antibody
Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis...
Published: April, 2020

Abstract: Merkel cell carcinoma (MCC) is a deadly skin cancer, and about 80% of its cases have been shown to harbor integrated Merkel polyomavirus in the tum... Read more »

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Beads
The endocannabinoid anandamide has an anti-inflammatory effect on C...
Published: April, 2020

Abstract: Endocannabinoids are important lipid-signaling mediators. Both protective and deleterious effects of endocannabinoids in the cardiovascular system ... Read more »

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Beads
CRISPR off-target detection with DISCOVER-seq.
Published: April, 2020

Abstract: DISCOVER-seq (discovery of in situ Cas off-targets and verification by sequencing) is a broadly applicable approach for unbiased CRISPR-Cas off-tar... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
An epigenetic map of malaria parasite development from host to vector.
Published: April, 2020

Abstract: The malaria parasite replicates asexually in the red blood cells of its vertebrate host employing epigenetic mechanisms to regulate gene expression... Read more »

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Antibody
The TGF-β profibrotic cascade targets ecto-5'-nucleotidase gene in ...
Published: April, 2020

Abstract: Progressive diabetic nephropathy (DN) and loss of renal function correlate with kidney fibrosis. Crosstalk between TGF-β and adenosinergic sig... Read more »

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Antibody
Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochr...
Published: April, 2020

Abstract: Heterochromatin regulation is critical for genomic stability. Different H3K9 methylation states have been discovered, with distinct roles in hetero... Read more »

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Antibody
Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenoca...
Published: April, 2020

Abstract: INTRODUCTION: Surgical procedure is the treatment of choice in early stage I lung adenocarcinoma. However, a considerable number of patients experi... Read more »

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IP-Star Compact
Endogenous retroviruses are a source of enhancers with oncogenic po...
Published: April, 2020

Abstract: Acute myeloid leukemia (AML) is a highly aggressive hematopoietic malignancy, defined by a series of genetic and epigenetic alterations, which resu... Read more »

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Antibody
TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-...
Published: March, 2020

Abstract: Loss-of-function mutations in the SDHB subunit of succinate dehydrogenase predispose patients to aggressive tumors characterized by pseudohypo... Read more »

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MagMeDIP kit Antibody iDeal ChIP-qPCR
CRISPR-based gene knockout screens reveal deubiquitinases involved ...
Published: March, 2020

Abstract: The major barrier to a HIV-1 cure is the persistence of latent genomes despite treatment with antiretrovirals. To investigate host factors which pr... Read more »

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Antibody CRISPR
Differential modulation of the androgen receptor for prostate cance...
Published: March, 2020

Abstract: Androgen receptor (AR) action is a hallmark of prostate cancer (PCa) with androgen deprivation being standard therapy. Yet, resistance arises and a... Read more »

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Antibody IPure kit
High density of unrepaired genomic ribonucleotides leads to Topoiso...
Published: March, 2020

Abstract: Cellular levels of ribonucleoside triphosphates (rNTPs) are much higher than those of deoxyribonucleoside triphosphates (dNTPs), thereby influencin... Read more »

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Antibody
Multi-omic analysis of gametogenesis reveals a novel signature at t...
Published: March, 2020

Abstract: Epigenetic regulation of gene expression is tightly controlled by the dynamic modification of histones by chemical groups, the diversity of which h... Read more »

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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Alu retrotransposons modulate Nanog expression through dynamic chan...
Published: March, 2020

Abstract: Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenet... Read more »

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Antibody
Anti-adipogenic signals at the onset of obesity-related inflammatio...
Published: March, 2020

Abstract: Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-a... Read more »

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Microplex Library Preparation kit
LXR Activation Induces a Proinflammatory Trained Innate Immunity-Ph...
Published: March, 2020

Abstract: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated th... Read more »

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Antibody
LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in E...
Published: March, 2020

Abstract: Growing evidence demonstrates that epithelial-mesenchymal transition (EMT) plays an important role in epithelial ovarian cancer (EOC) progression a... Read more »

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DNA Methylation Profiling (RRBS Service)
CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: ...
Published: March, 2020

Abstract: CDK7, a transcriptional cyclin-dependent kinase, is emerging as a novel cancer target. Triple-negative breast cancers (TNBC) but not estrogen recep... Read more »

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Antibody
Genome-wide DNA Methylation Analysis of Mantle Edge and Mantle Cent...
Published: March, 2020

Abstract: DNA methylation is a type of epigenetic modification that alters gene expression without changing the DNA sequence and mediates some cases of pheno... Read more »

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MagMeDIP kit
Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidn...
Published: March, 2020

Abstract: BACKGROUND: Cytosine methylation is an epigenetic mark that dictates cell fate and response to stimuli. The timing and establishment of methylation... Read more »

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Premium RRBS Kit
ChromID identifies the protein interactome at chromatin marks.
Published: March, 2020

Abstract: Chromatin modifications regulate genome function by recruiting proteins to the genome. However, the protein composition at distinct chromatin modif... Read more »

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Antibody

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