Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genome-wide analysis of DNA methylation to identify genes and pathw...
Published: September, 2018

Abstract: DNA methylation is an epigenetic modification, which is important for gene expression regulation. Although genome-wide DNA methylation studies have... Read more »

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MagMeDIP kit
Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting...
Published: September, 2018

Abstract: How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E... Read more »

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Antibody
Impact of human sepsis on CCCTC-binding factor associated monocyte ...
Published: September, 2018

Abstract: BACKGROUND: Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for... Read more »

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Antibody
MIWI2 targets RNAs transcribed from piRNA-dependent regions to driv...
Published: September, 2018

Abstract: Argonaute/Piwi proteins can regulate gene expression via RNA degradation and translational regulation using small RNAs as guides. They also promote... Read more »
The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidi...
Published: September, 2018

Abstract: Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues... Read more »

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CATS
NGS analysis of total small non coding RNAs from low input RNA from...
Published: September, 2018

Abstract: Circulating miRNAs are favored for biomarker candidates as they can reflect tissue specific miRNA dysregulation in disease contexts. Moreover, they... Read more »

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CATS
FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis e...
Published: September, 2018

Abstract: The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In ... Read more »

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ChIP-seq
Dot1 promotes H2B ubiquitination by a methyltransferase-independent...
Published: September, 2018

Abstract: The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H... Read more »
Mapping molecular landmarks of human skeletal ontogeny and pluripot...
Published: September, 2018

Abstract: Tissue-specific gene expression defines cellular identity and function, but knowledge of early human development is limited, hampering application ... Read more »
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purki...
Published: September, 2018

Abstract: In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of sy... Read more »

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Antibody
Transcription Elongation Can Affect Genome 3D Structure.
Published: September, 2018

Abstract: How transcription affects genome 3D organization is not well understood. We found that during influenza A (IAV) infection, rampant transcription ra... Read more »
Genome-wide measurement of local nucleosome array regularity and sp...
Published: September, 2018

Abstract: The nature of chromatin as regular succession of nucleosomes has gained iconic status. However, since most nucleosomes in metazoans are poorly posi... Read more »

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iDeal Library Preparation Kit
Differential DNA methylation of potassium channel KCa3.1 and immune...
Published: August, 2018

Abstract: Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary d... Read more »
High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation r...
Published: August, 2018

Abstract: While suppression of specific genes through aberrant promoter methylation contributes to different diseases including organ fibrosis, gene-specific... Read more »

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OneDay ChIP Kit
Polycomb repressive complex 1 shapes the nucleosome landscape but n...
Published: August, 2018

Abstract: Polycomb group (PcG) proteins are transcriptional repressors that play important roles in regulating gene expression during animal development. In ... Read more »

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Antibody
Lamin B1 mapping reveals the existence of dynamic and functional eu...
Published: August, 2018

Abstract: Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic... Read more »

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Beads
Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: ...
Published: August, 2018

Abstract: BACKGROUND: Many neurodegenerative diseases are caused by nucleotide repeat expansions, but most expansions, like the C9orf72 'GGGGCC' (GC) repeat ... Read more »

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Megaruptor
Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response ...
Published: August, 2018

Abstract: Activation of macrophages by inflammatory stimuli induces reprogramming of mitochondrial metabolism to support the production of pro-inflammatory c... Read more »
The complete methylome of an entomopathogenic bacterium reveals the...
Published: August, 2018

Abstract: DNA methylation can serve to control diverse phenomena in eukaryotes and prokaryotes, including gene regulation leading to cell differentiation. In... Read more »

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Megaruptor
Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.
Published: August, 2018

Abstract: Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to... Read more »

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OneDay ChIP Kit
The Arabidopsis LDL1/2-HDA6 histone modification complex is functio...
Published: August, 2018

Abstract: In Arabidopsis, the circadian clock central oscillator genes are important cellular components to generate and maintain circadian rhythms. There is... Read more »

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Antibody
Canonical PRC2 function is essential for mammary gland development ...
Published: August, 2018

Abstract: Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone ... Read more »

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Antibody
The histone demethylase Jarid1b mediates angiotensin II-induced end...
Published: August, 2018

Abstract: AIM: The histone demethylase Jarid1b limits gene expression by removing the active methyl mark from histone3 lysine4 at gene promoter regions. A va... Read more »

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ChIP-qPCR
The effect of Jun dimerization on neurite outgrowth and motif binding.
Published: August, 2018

Abstract: Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known ... Read more »

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ChIP-qPCR
HIV-2/SIV viral protein X counteracts HUSH repressor complex.
Published: August, 2018

Abstract: To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2) have evolved auxiliary proteins that target cell restrictio... Read more »

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Antibody HighCell ChIP kit
Atopic asthma after rhinovirus-induced wheezing is associated with ...
Published: August, 2018

Abstract: Children with rhinovirus-induced severe early wheezing have an increased risk of developing asthma later in life. The exact molecular mechanisms fo... Read more »
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scler...
Published: August, 2018

Abstract: OBJECTIVE: Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of met... Read more »
TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Published: July, 2018

Abstract: Testis-specific protein, Y-encoded-like 2 (TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously sh... Read more »

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Antibody
Wnt receptor Frizzled 8 is a target of ERG in prostate cancer
Published: July, 2018

Abstract: Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men. Many molecular changes have been detailed during PCa progression. ... Read more »

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ChIP-qPCR
Longitudinal Effects of Developmental Bisphenol A Exposure on Epige...
Published: July, 2018

Abstract: BACKGROUND: Epigenetic machinery plays an important role in genomic imprinting, a developmental process that establishes parent-of-origin-specific ... Read more »

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