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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Two-factor authentication underpins the precision of the piRNA pathway
Published: September, 2024
Abstract: The PIWI-interacting RNA (piRNA) pathway guides the DNA methylation of young, active transposons during germline development in male mice. piRNAs t... Read more »
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CUT&Tag
Multiplex, single-cell CRISPRa screening for cell type specific reg...
Published: September, 2024
Abstract: CRISPR-based gene activation (CRISPRa) is a strategy for upregulating gene expression by targeting promoters or enhancers in a tissue/cell-type spe... Read more »
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Tagmentase
Single-cell multi-omics, spatial transcriptomics and systematic per...
Published: September, 2024
Abstract: Cranial neural crest (NC) cells, which can migrate, adopt multiple fates, and form most of the craniofacial skeleton, are an excellent model for st... Read more »
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Antibody True MicroChIP kit
Optimization of ribosome profiling in plants including structural a...
Published: September, 2024
Abstract: Background Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Acr... Read more »
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D-Plex small RNA-seq
Systematic prioritization of functional variants and effector genes...
Published: September, 2024
Abstract: Genome-wide association studies of colorectal cancer (CRC) have identified 170 autosomal risk loci. However, for most of these, the functional vari... Read more »
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Antibody
An ERRα-ZEB1 transcriptional signature predicts survival in triple-...
Published: September, 2024
Abstract: Background. Transcription factors (TFs) act together with co-regulators to modulate the expression of their target genes, which eventually dictate... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Auto-expansion of in vivo HDAd-transduced hematopoietic stem cells ...
Published: September, 2024
Abstract: We developed an in vivo hematopoietic stem cell (HSC) gene therapy approach that does not require cell transplantation. To achieve t... Read more »
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Tagmentase
Nuclear lamin A/C phosphorylation by loss of androgen receptor lead...
Published: September, 2024
Abstract: Alterations in nuclear structure and function are hallmarks of cancer cells. Little is known about these changes in Cancer-Associated Fibroblasts (... Read more »
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iDeal ChIP-seq Kit for Transcription Factors Tagmentase
A critical role for HNF4α in polymicrobial sepsis-associated metabo...
Published: September, 2024
Abstract: In sepsis, limited food intake and increased energy expenditure induce a starvation response, which is compromised by a quick decline in the expres... Read more »
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Tagmentase
Bivalent chromatin accommodates survivin and BRG1/SWI complex to ac...
Published: September, 2024
Abstract: Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3)... Read more »
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Antibody
Single cell genome and epigenome co-profiling reveals hardwiring an...
Published: September, 2024
Abstract: Understanding the impact of genetic alterations on epigenomic phenotypes during breast cancer progression is challenging with unimodal measurements... Read more »
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Tagmentase
Precision and efficacy of RNA-guided DNA integration in high-expres...
Published: September, 2024
Abstract: Gene replacement therapies primarily rely on adeno-associated virus (AAV) vectors for transgene expression. However, episomal expression can declin... Read more »
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Tagmentase
Triphenyl Phosphate Alters Methyltransferase Expression and Induces...
Published: August, 2024
Abstract: Emerging environmental contaminants, organophosphate flame retardants (OPFRs), pose significant threats to ecosystems and human health. Despite num... Read more »
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Premium RRBS Kit
An atlas of the human liver diurnal transcriptome and its perturbat...
Published: August, 2024
Abstract: Chronic liver disease and cancer are global health challenges. The role of the circadian clock as a regulator of liver physiology and disease is we... Read more »
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Microplex Library Preparation kit
Peripheral nervous system mediates body-wide stem cell activation f...
Published: August, 2024
Abstract: Many species throughout the animal kingdom naturally regenerate complex body parts following amputation. Most research in appendage regeneration ha... Read more »
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Tagmentase
RNA sequestration in P-bodies sustains myeloid leukaemia
Published: August, 2024
Abstract: Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified re... Read more »
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Antibody CUT&Tag
Maternal prenatal stress induces sex-dependent changes in tRNA frag...
Published: August, 2024
Abstract: Maternal perceived prenatal stress (PPS) is a known risk factor for diverse developmental impairments in newborns, but the underlying molecular pro... Read more »
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D-Plex small RNA-seq
A PRE loop at the dac locus acts as a topological chromatin structu...
Published: August, 2024
Abstract: Three-dimensional (3D) genome folding has a fundamental role in the regulation of developmental genes by facilitating or constraining chromatin int... Read more »
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ChIP-qPCR
Temporal and spatial niche partitioning in a retrotransposon commun...
Published: August, 2024
Abstract: Transposable elements (TEs), widespread genetic parasites, pose potential threats to the stability of their host genomes. Hence, the interactions o... Read more »
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ATAC-seq
Inherited defects of piRNA biogenesis cause transposon de-repressio...
Published: August, 2024
Abstract: piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dy... Read more »
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D-Plex small RNA-seq
Detection of genome structural variation in normal cells and tissue...
Published: August, 2024
Abstract: Detecting somatic mutations in normal cells and tissues is notoriously challenging due to their low abundance, orders of magnitude below the sequen... Read more »
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Tagmentase
Association between TNF-α, cortisol levels, and exposure to PM10 an...
Published: August, 2024
Abstract: Purpose The most harmful atmospheric pollutant for human health is particulate matter (PM). We analyzed the correlation between short-term lag exp... Read more »
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MagMeDIP kit
Human induced pluripotent stem cells for live cell cycle monitoring...
Published: August, 2024
Abstract: The fluorescence ubiquitination cell cycle inhibitor (FUCCI) has been introduced to monitor cell cycle activity in living cells, including human in... Read more »
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Antibody CRISPR
LL37/self-DNA complexes mediate monocyte reprogramming
Published: August, 2024
Abstract: LL37 alone and in complex with self-DNA triggers inflammatory responses in myeloid cells and plays a crucial role in the development of systemic au... Read more »
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Antibody
Galectin 3-binding protein (LGALS3BP) depletion attenuates hepatic ...
Published: July, 2024
Abstract: Background Increased Galectin 3-binding protein (LGALS3BP) serum levels have been used to assess hepatic fibrosis stages and the severity of hep... Read more »
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ATAC-seq
Innate immune training restores pro-reparative myeloid functions to...
Published: July, 2024
Abstract: The reduced ability of the central nervous system to regenerate with increasing age limits functional recovery following demyelinating injury. Prev... Read more »
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Antibody iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Biochemical role of FOXM1-dependent histone linker H1B in human epi...
Published: July, 2024
Abstract: Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and different... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
A multiomic atlas of the aging hippocampus reveals molecular change...
Published: July, 2024
Abstract: Aging involves the deterioration of organismal function, leading to the emergence of multiple pathologies. Environmental stimuli, including lifesty... Read more »
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Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural sig...
Published: July, 2024
Abstract: Fusion-positive rhabdomyosarcoma is an aggressive pediatric cancer molecularly characterized by arrested myogenesis. The defining genetic driver, P... Read more »
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Tagmentase
Loss of tumor suppressors promotes inflammatory tumor microenvironm...
Published: July, 2024
Abstract: Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we repo... Read more »
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Antibody CRISPR

Events

  • American Association of Cancer Research (AACR)
    Chicago (IL), USA
    Apr 25-Apr 30, 2025
  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
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