Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

ΔNp63-driven recruitment of myeloid-derived suppressor cells promot...
Published: October, 2018

Abstract: Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastas... Read more »

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ChIP-seq
H3K4/K9 acetylation and Lr28-mediated expression of six leaf rust r...
Published: October, 2018

Abstract: Development of leaf rust-resistant cultivars is a priority during wheat breeding, since leaf rust causes major losses in yield. Resistance against ... Read more »

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Beads
Prospective Isolation and Characterization of Genetically and Funct...
Published: October, 2018

Abstract: Intra-tumor heterogeneity caused by clonal evolution is a major problem in cancer treatment. To address this problem, we performed label-free quant... Read more »

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Microplex Library Preparation kit
Directional high-throughput sequencing of RNAs without gene-specifi...
Published: October, 2018

Abstract: Ribosomal RNA analysis is a useful tool for characterization of microbial communities. However, the lack of broad-range primers has hampered the si... Read more »

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CATS
SOX4 inhibits oligodendrocyte differentiation of embryonic neural s...
Published: October, 2018

Abstract: SOX4 has been shown to promote neuronal differentiation both in the adult and embryonic neural progenitors. Ectopic SOX4 expression has also been s... Read more »

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Antibody
Cellular localization of the cell cycle inhibitor Cdkn1c controls g...
Published: October, 2018

Abstract: Adult skeletal muscle maintenance and regeneration depend on efficient muscle stem cell (MuSC) functions. The mechanisms coordinating cell cycle wi... Read more »

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Antibody
Integrated analysis of DNA methylation profiling and gene expressio...
Published: October, 2018

Abstract: BACKGROUND: Aberrant DNA methylation occurs frequently in cancer. The aim of this study was to identify novel methylation markers in lung cancer in... Read more »

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Antibody
Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Choles...
Published: October, 2018

Abstract: The mechanisms underlying sterol transport in mammalian cells are poorly understood. In particular, how cholesterol internalized from HDL is made a... Read more »

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Master Mix
Genomic Structural Variations Within Five Continental Populations of .
Published: October, 2018

Abstract: Chromosomal structural variations (SV) including insertions, deletions, inversions, and translocations occur within the genome and can have a signi... Read more »

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Megaruptor
PRC2 targeting is a therapeutic strategy for EZ score defined high-...
Published: October, 2018

Abstract: BACKGROUND: Multiple myeloma (MM) is a malignant plasma cell disease with a poor survival, characterized by the accumulation of myeloma cells (MMCs... Read more »

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Antibody IPure kit IP-Star Compact iDeal ChIP-seq Kit for Histones
Cellular localization of the cell cycle inhibitor Cdkn1c controls g...
Published: October, 2018

Abstract: Adult skeletal muscle maintenance and regeneration depend on efficient muscle stem cell (MuSC) functions. The mechanisms coordinating cell cycle wi... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy du...
Published: October, 2018

Abstract: NF-E2-related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidat... Read more »

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Antibody
Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone ...
Published: October, 2018

Abstract: Proteomic analysis of histones has shown that they are subject to a superabundance of acylations, which extend far beyond acetylation, to include: ... Read more »

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IPure kit
The Itaconate Pathway Is a Central Regulatory Node Linking Innate I...
Published: October, 2018

Abstract: Sepsis involves simultaneous hyperactivation of the immune system and immune paralysis, leading to both organ dysfunction and increased susceptibil... Read more »

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Antibody Bioruptor Plus
Long-read sequencing identified a causal structural variant in an e...
Published: September, 2018

Abstract: Background: For a proportion of individuals judged clinically to have a recessive Mendelian disease, only one heterozygous pathogenic variant can b... Read more »

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Megaruptor
Gap junction protein Connexin-43 is a direct transcriptional regula...
Published: September, 2018

Abstract: Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes. Here, we demonstrat... Read more »

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Antibody
Histone variant H2A.Z deposition and acetylation directs the canoni...
Published: September, 2018

Abstract: A fundamental as yet incompletely understood feature of Notch signal transduction is a transcriptional shift from repression to activation that dep... Read more »

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Antibody
Development of PCR screening assays focused on genecoding sequences...
Published: September, 2018

Abstract: For the detection of genetically modifed organisms (GMO), screening is the frst step used to determine if a GMO or its derived products are present... Read more »

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Master Mix
Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to t...
Published: September, 2018

Abstract: Protein arginine methyltransferase 6 (PRMT6) catalyzes asymmetric dimethylation of histone H3 at arginine 2 (H3R2me2a). This mark has been reported... Read more »

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Microplex Library Preparation kit
UCP1 transrepression in Brown Fat in vivo and mineralocorticoid rec...
Published: September, 2018

Abstract: OBJECTIVES: The mineralocorticoid receptor (MR), a hormone-activated transcription factor, besides its role in controlling hydroelectrolytic homeos... Read more »

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Antibody HighCell ChIP kit
Genome-wide analysis of DNA methylation to identify genes and pathw...
Published: September, 2018

Abstract: DNA methylation is an epigenetic modification, which is important for gene expression regulation. Although genome-wide DNA methylation studies have... Read more »

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MagMeDIP kit
Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting...
Published: September, 2018

Abstract: How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E... Read more »

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Antibody
Impact of human sepsis on CCCTC-binding factor associated monocyte ...
Published: September, 2018

Abstract: BACKGROUND: Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for... Read more »

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Antibody
MIWI2 targets RNAs transcribed from piRNA-dependent regions to driv...
Published: September, 2018

Abstract: Argonaute/Piwi proteins can regulate gene expression via RNA degradation and translational regulation using small RNAs as guides. They also promote... Read more »

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Antibody
The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidi...
Published: September, 2018

Abstract: Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues... Read more »

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CATS
NGS analysis of total small non coding RNAs from low input RNA from...
Published: September, 2018

Abstract: Circulating miRNAs are favored for biomarker candidates as they can reflect tissue specific miRNA dysregulation in disease contexts. Moreover, they... Read more »

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CATS
FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis e...
Published: September, 2018

Abstract: The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In ... Read more »

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ChIP-seq
Dot1 promotes H2B ubiquitination by a methyltransferase-independent...
Published: September, 2018

Abstract: The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H... Read more »
Mapping molecular landmarks of human skeletal ontogeny and pluripot...
Published: September, 2018

Abstract: Tissue-specific gene expression defines cellular identity and function, but knowledge of early human development is limited, hampering application ... Read more »

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Antibody LowCell ChIP kit
Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryo...
Published: September, 2018

Abstract: Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have id... Read more »

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Antibody

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