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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Heterochromatin protein 1γ deficiency decreases histone H3K27 methy...
Published: January, 2020

Abstract: Heterochromatin protein (HP) 1γ, a component of heterochromatin in eukaryotes, is involved in H3K9 methylation. Although HP1γ is expres... Read more »

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LowCell ChIP kit
A multiplexed gRNA piggyBac transposon system facilitates efficient...
Published: January, 2020

Abstract: CRISPR-Cas9-mediated gene interference (CRISPRi) and activation (CRISPRa) approaches hold promise for functional gene studies and genome-wide scree... Read more »

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HighCell ChIP kit
The complete mitochondrial genome of Taxus cuspidata (Taxaceae): ei...
Published: January, 2020

Abstract: BACKGROUND: Gymnosperms represent five of the six lineages of seed plants. However, most sequenced plant mitochondrial genomes (mitogenomes) have b... Read more »

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Megaruptor
miR-155 inhibits mitophagy through suppression of BAG5, a partner p...
Published: January, 2020

Abstract: Removal of dysfunctional mitochondria is essential step to maintain normal cell physiology, and selective autophagy in mitochondria, called mitopha... Read more »

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Antibody
Dual-initiation promoters with intertwined canonical and TCT/TOP tr...
Published: January, 2020

Abstract: Variations in transcription start site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcriptional RNA fate... Read more »

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Microplex Library Preparation kit
Multisite Evaluation of Next-Generation Methods for Small RNA Quant...
Published: January, 2020

Abstract: Small RNAs (smRNAs) are important regulators of many biologic processes and are now most frequently characterized using Illumina sequencing. Howeve... Read more »

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CATS
Alteration in global DNA methylation status following preconditioni...
Published: January, 2020

Abstract: Preconditioning peripheral nerve injury primes the sensory neurons in the dorsal root ganglia (DRGs) to acquire axon regeneration competence. Trans... Read more »

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MagMeDIP kit
A highly contiguous genome assembly of the bat hawkmoth Hyles vespe...
Published: January, 2020

Abstract: BACKGROUND: Adapted to different ecological niches, moth species belonging to the Hyles genus exhibit a spectacular diversity of larval color patte... Read more »

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Megaruptor
AP-1 activity induced by co-stimulation is required for chromatin o...
Published: January, 2020

Abstract: Activation of T cells is dependent on the organized and timely opening and closing of chromatin. Herein, we identify AP-1 as the transcription fact... Read more »

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IP-Star Antibody
A comprehensive epigenomic analysis of phenotypically distinguishab...
Published: January, 2020

Abstract: BACKGROUND: Daphnia species reproduce by cyclic parthenogenesis involving both sexual and asexual reproduction. The sex of the offspring is environ... Read more »

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Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
ALK4 coordinates extracellular and intrinsic signals to regulate de...
Published: January, 2020

Abstract: Although the role of transcription factors in fate specification of cortical interneurons is well established, how these interact with extracellula... Read more »

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HighCell ChIP kit
Nanopore Sequencing and Its Clinical Applications.
Published: January, 2020

Abstract: Nanopore sequencing is a method for determining the order and modifications of DNA/RNA nucleotides by detecting the electric current variation... Read more »

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Megaruptor
Analysis of Histone Modifications in Rodent Pancreatic Islets by Na...
Published: January, 2020

Abstract: The islets of Langerhans are clusters of cells dispersed throughout the pancreas that produce several hormones essential for controlling a variety ... Read more »

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Antibody
The Inhibition of the Histone Methyltransferase EZH2 by DZNEP or Si...
Published: December, 2019

Abstract: In France, prostate cancer is the most common cancer in men (Bray et al., 2018). Previously, our team has reported the involvement of epigenetic fa... Read more »

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Antibody
SMaSH: Sample matching using SNPs in humans.
Published: December, 2019

Abstract: BACKGROUND: Inadvertent sample swaps are a real threat to data quality in any medium to large scale omics studies. While matches between samples fr... Read more »

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MethylCap IP-Star Compact
Charting the cis-regulome of activated B cells by coupling structur...
Published: December, 2019

Abstract: Cis-regulomes underlying immune-cell-specific genomic states have been extensively analyzed by structure-based chromatin profiling. By coupling suc... Read more »

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Antibody
Unraveling the role of H3K4 trimethylation and lncRNA HOTAIR in SAT...
Published: December, 2019

Abstract: The modification of chromatin influences host transcriptional programs during bacterial infection, at times skewing the balance in favor of pathoge... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Allelic H3K27me3 to allelic DNA methylation switch maintains noncan...
Published: December, 2019

Abstract: Faithful maintenance of genomic imprinting is essential for mammalian development. While germline DNA methylation–dependent (canonical) impri... Read more »

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Antibody
Functionally Annotating Regulatory Elements in the Equine Genome Us...
Published: December, 2019

Abstract: One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within anim... Read more »

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Antibody IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Combinatorial action of NF-Y and TALE at embryonic enhancers define...
Published: December, 2019

Abstract: Animal embryogenesis is initiated by maternal factors, but zygotic genome activation (ZGA) shifts regulatory control to the embryo during blastula ... Read more »

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Microplex Library Preparation kit
H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammat...
Published: December, 2019

Abstract: Natural killer (NK) cells are unique players in innate immunity and, as such, an attractive target for immunotherapy. NK cells display immune memor... Read more »

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Antibody
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signa...
Published: December, 2019

Abstract: In breast cancer, Lysine-specific demethylase-1 (LSD1) and other lysine demethylases (KDMs), such as Lysine-specific demethylase 6A also known as U... Read more »

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Antibody
Increased presence and differential molecular imprinting of transit...
Published: December, 2019

Abstract: Psoriasis is a very common chronic inflammatory skin disease characterized by epidermal thickening and scaling resulting from keratinocyte hyperpro... Read more »

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MethylCap
Trained immunity modulates inflammation-induced fibrosis.
Published: December, 2019

Abstract: Chronic inflammation and fibrosis can result from inappropriately activated immune responses that are mediated by macrophages. Macrophages can acqu... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Mkt1 is required for RNAi-mediated silencing and establishment of h...
Published: December, 2019

Abstract: Constitutive domains of repressive heterochromatin are maintained within the fission yeast genome through self-reinforcing mechanisms involving his... Read more »

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Antibody
A Study of High-Grade Serous Ovarian Cancer Origins Implicates the ...
Published: December, 2019

Abstract: Fallopian tube secretory epithelial cells (FTSECs) are likely the main precursor cell type of high-grade serous ovarian cancers (HGSOCs), but these... Read more »

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Antibody
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 in...
Published: December, 2019

Abstract: As a member of the 11-gene "death-from-cancer" gene expression signature, overexpression of the Ubiquitin-Specific Protease 22 (USP22) was associat... Read more »

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Antibody
SIRT1/2 orchestrate acquisition of DNA methylation and loss of hist...
Published: December, 2019

Abstract: Sirtuins 1 and 2 (SIRT1/2) are two NAD-dependent deacetylases with major roles in inflammation. In addition to deacetylating histones and other pro... Read more »

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Antibody LowCell ChIP kit
Sodium valproate and 5-aza-2'-deoxycytidine differentially modulate...
Published: December, 2019

Abstract: Sodium valproate/valproic acid (VPA), a histone deacetylase inhibitor, and 5-aza-2-deoxycytidine (5-aza-CdR), a DNA methyltransferase 1 (DNMT1) inh... Read more »

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Antibody
Episo: quantitative estimation of RNA 5-methylcytosine at isoform l...
Published: December, 2019

Abstract: MOTIVATION: RNA 5-methylcytosine (m5C) is a type of post-transcriptional modification that may be involved in numerous biological processes and tum... Read more »

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Antibody

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