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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Detection of renal cell carcinoma using plasma and urine cell-free ...
Published: June, 2020

Abstract: Improving early cancer detection has the potential to substantially reduce cancer-related mortality. Cell-free methylated DNA immunoprecipitation a... Read more »

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MagMeDIP kit Antibody IPure kit
Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi...
Published: June, 2020

Abstract: How the epigenetic landscape is established in development is still being elucidated. Here, we uncover developmental pluripotency associated 2 and ... Read more »

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Antibody Microplex Library Preparation kit
Tandem gene duplications drive divergent evolution of caffeine and ...
Published: June, 2020

Abstract: BACKGROUND: Plants have evolved a panoply of specialized metabolites that increase their environmental fitness. Two examples are caffeine, a purine... Read more »

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Megaruptor
Vulnerability of drug-resistant EML4-ALK rearranged lung cancer to ...
Published: June, 2020

Abstract: A subset of lung adenocarcinomas is driven by the EML4-ALK translocation. Even though ALK inhibitors in the clinic lead to excellent initial respon... Read more »

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Antibody Microplex Library Preparation kit
Genomic deregulation of PRMT5 supports growth and stress tolerance ...
Published: June, 2020

Abstract: Patients suffering from chronic lymphocytic leukemia (CLL) display highly diverse clinical courses ranging from indolent cases to aggressive diseas... Read more »

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Antibody
Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is requ...
Published: June, 2020

Abstract: BACKGROUND: Stable gene repression is essential for normal growth and development. Polycomb repressive complexes 1 and 2 (PRC1&2) are involved ... Read more »

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IPure kit Microplex Library Preparation kit
DNA methylation dynamics underlie metamorphic gene regulation progr...
Published: June, 2020

Abstract: Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial for brain development.... Read more »

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Antibody MethylCap
An optimised Chromatin Immunoprecipitation (ChIP) method for starch...
Published: June, 2020

Abstract: All flowering plants have evolved through multiple rounds of polyploidy throughout the evolutionary process. Intergenomic interactions between subg... Read more »

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Antibody
Diversity of Pectobacteriaceae Species in Potato Growing Regions in...
Published: June, 2020

Abstract: Dickeya and Pectobacterium pathogens are causative agents of several diseases that affect many crops worldwide. This work investigated the species ... Read more »

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Megaruptor
Estrogen induces dynamic ERα and RING1B recruitment to control gene...
Published: June, 2020

Abstract: RING1B, a core Polycomb repressive complex 1 subunit, is a histone H2A ubiquitin ligase essential for development. RING1B is overexpressed in patie... Read more »

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Antibody
Global analysis of histone modifications and long-range chromatin i...
Published: June, 2020

Abstract: BACKGROUND: Acetylation and methylation of histones alter the chromatin structure and accessibility that affect transcriptional regulators binding ... Read more »

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Antibody
Delineating the early transcriptional specification of the mammalia...
Published: June, 2020

Abstract: The genome-scale transcriptional programs that specify the mammalian trachea and esophagus are unknown. Though NKX2-1 and SOX2 are hypothesized to ... Read more »

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Microplex Library Preparation kit
CTCF is dispensable for immune cell transdifferentiation but facili...
Published: June, 2020

Abstract: Three-dimensional organization of the genome is important for transcriptional regulation. In mammals, CTCF and the cohesin complex create submegaba... Read more »

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Beads
Dysregulation of BRD4 Function Underlies the Functional Abnormaliti...
Published: June, 2020

Abstract: Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MeCP2), is one of the most prevalent intellectual disorders withou... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Major Impacts of Widespread Structural Variation on Gene Expression...
Published: June, 2020

Abstract: Structural variants (SVs) underlie important crop improvement and domestication traits. However, resolving the extent, diversity, and quantitative ... Read more »

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Megaruptor
TGFα Promotes Chemoresistance of Malignant Pleural Mesothelioma.
Published: June, 2020

Abstract: : There is no standard chemotherapy for refractory or relapsing malignant pleural mesothelioma (MPM). Our previous reports nevertheless indicated t... Read more »

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CATS
A conserved RNA degradation complex required for spreading and epig...
Published: June, 2020

Abstract: Heterochromatic domains containing histone H3 lysine 9 methylation (H3K9me) can be epigenetically inherited independently of underlying DNA sequenc... Read more »

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Antibody
Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is ...
Published: June, 2020

Abstract: Before zygotic genome activation (ZGA), the quiescent genome undergoes reprogramming to transition into the transcriptionally active state. However... Read more »

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Antibody
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of m...
Published: June, 2020

Abstract: We have generated mouse models of malignant mesothelioma (MM) based upon disruption of the Bap1, Nf2, and Cdkn2ab tumor suppressor loci in various ... Read more »

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iDeal ChIP-seq Kit for Histones
Inactivation of Arid1a in the endometrium is associated with endome...
Published: June, 2020

Abstract: Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidat... Read more »

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ChIP Cross-link Gold
A Germline Mutation in the Gene Is a Candidate for Familial Non-Me...
Published: June, 2020

Abstract: Non-medullary thyroid cancer (NMTC) is a common endocrine malignancy with a genetic basis that has yet to be unequivocally established. In a recent... Read more »

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IPure kit
AXR1 affects DNA methylation independently of its role in regulatin...
Published: June, 2020

Abstract: Meiotic crossovers (COs) are important for reshuffling genetic information between homologous chromosomes and they are essential for their correct ... Read more »

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Antibody
Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforc...
Published: May, 2020

Abstract: BACKGROUND: The histone 3 lysine 4 (H3K4) monomethylase KMT2C is mutated across several cancer types; however, the effects of mutations on epigenom... Read more »

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iDeal ChIP-seq Kit for Histones
The 20S proteasome activator PA28γ controls the compaction of chrom...
Published: May, 2020

Abstract: The nuclear PA28γ is known to activate the 20S proteasome, but its precise cellular functions remains unclear. Here, we identify PA28γ ... Read more »

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Antibody
Integration of high-throughput reporter assays identify a critical ...
Published: May, 2020

Abstract: The Ikzf1 locus encodes the lymphoid specific transcription factor Ikaros, which plays an essential role in both T and B cell differentiation, whil... Read more »

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Antibody
Measuring Histone Modifications in the Human Parasite Schistosoma m...
Published: May, 2020

Abstract: DNA-binding proteins play critical roles in many major processes such as development and sexual biology of Schistosoma mansoni and are important fo... Read more »

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IP-Star Antibody
Histone post-translational modifications in Silene latifolia X and ...
Published: May, 2020

Abstract: Silene latifolia is a model organism to study evolutionary young heteromorphic sex chromosome evolution in plants. Previous research indicates a Y-... Read more »

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Antibody
AP-1 controls the p11-dependent antidepressant response.
Published: May, 2020

Abstract: Selective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed drugs for mood disorders. While the mechanism of SSRI action is stil... Read more »

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Antibody Beads ChIP Cross-link Gold
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-...
Published: May, 2020

Abstract: Despite the clinical success of Androgen Receptor (AR)-targeted therapies, reactivation of AR signalling remains the main driver of castration-resi... Read more »

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Antibody IP-Star Compact
Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis I...
Published: May, 2020

Abstract: Somatic stem cells expand massively during tissue regeneration, which might require control of cell fitness, allowing elimination of non-competitiv... Read more »

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Antibody

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