A chromosome-scale genome assembly of cucumber (Cucumis sativus L.). Published: June, 2019 Abstract:
BACKGROUND: Accurate and complete reference genome assemblies are fundamental for biological research. Cucumber is an important vegetable crop and model system for sex determination and vascular biology. Low-coverage Sanger sequences and high-cove... Read more »
The alternative reality of plant mitochondrial DNA Published: March, 2019 Abstract:
Plant mitochondrial genomes are usually assembled and displayed as circular maps based on the widely-held assumption that circular genome molecules are the primary form of mitochondrial DNA, despite evidence to the contrary. Many plant mitochondri... Read more »
Characterizing the Major Structural Variant Alleles of the Human Genome. Published: January, 2019 Abstract:
In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen human genomes. We sequence resolved 99,604 insertions, deletions, and inversions including 2,238 (1... Read more »
Improved reference genome of Aedes aegypti informs arbovirus vector control. Published: November, 2018 Abstract:
Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress in understanding the biology of mosquitoes and developing the tools to... Read more »
Whole-genome landscape of Medicago truncatula symbiotic genes. Published: November, 2018 Abstract:
Advances in deciphering the functional architecture of eukaryotic genomes have been facilitated by recent breakthroughs in sequencing technologies, enabling a more comprehensive representation of genes and repeat elements in genome sequence assemb... Read more »
The Genomic Basis of Color Pattern Polymorphism in the Harlequin Ladybird. Published: October, 2018 Abstract:
Many animal species comprise discrete phenotypic forms. A common example in natural populations of insects is the occurrence of different color patterns, which has motivated a rich body of ecological and genetic research [1-6]. The occurrence of d... Read more »
Long-read sequence capture of the hemoglobin gene clusters across gadid species. Published: October, 2018 Abstract:
Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Most studies have so far focused on the exome using short-read technology. These approaches are not de... Read more »
Genomic Structural Variations Within Five Continental Populations of . Published: October, 2018 Abstract:
Chromosomal structural variations (SV) including insertions, deletions, inversions, and translocations occur within the genome and can have a significant effect on organismal phenotype. Some of these effects are caused by structural variations con... Read more »
Long-read sequence capture of the haemoglobin gene clusters across codfish species. Published: August, 2018 Abstract:
Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Most studies have so far focused on the exome using short-read technology. These approaches are not de... Read more »
A high-quality genome sequence of Rosa chinensis to elucidate ornamental traits. Published: June, 2018 Abstract:
Rose is the world's most important ornamental plant, with economic, cultural and symbolic value. Roses are cultivated worldwide and sold as garden roses, cut flowers and potted plants. Roses are outbred and can have various ploidy levels. Our obje... Read more »
Draft genome of the Peruvian scallop Argopecten purpuratus. Published: April, 2018 Abstract:
Background: The Peruvian scallop, Argopecten purpuratus, is mainly cultured in southern Chile and Peru was introduced into China in the last century. Unlike other Argopecten scallops, the Peruvian scallop normally has a long life span of up to 7 t... Read more »
Overview of Next-Generation Sequencing Technologies. Published: April, 2018 Abstract:
High throughput DNA sequencing methodology (next generation sequencing; NGS) has rapidly evolved over the past 15 years and new methods are continually being commercialized. As the technology develops, so do increases in the number of correspondin... Read more »
Comparative Analysis of Ralstonia solanacearum Methylomes Published: April, 2017 Abstract:
Ralstonia solanacearum is an important soil-borne plant pathogen with broad geographical distribution and the ability to cause wilt disease in many agriculturally important crops. Genome sequencing of multiple R. solanacearum strains has identifie... Read more »
Microevolution of Burkholderia pseudomallei during an acute infection. Published: September, 2014 Abstract:
We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for... Read more »
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