Shearing technologies

Bioruptor^®

Best Workflow Practices for
ChIP-seq Analysis

Diagenode focuses on state-of-the-art preparation of high quality biological and chemical samples by developing the industry’s most advanced water bath sonicators and hydrodynamic devices. Our instruments are ideal for a number of applications in various fields of studies including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.

Technology explained

Reproductibility is our priority

An affordable instrument for wide range of applications

Designed for any researchers, the Bioruptor gives the user the right level of flexibility.

	Bioruptor	Cup Horn Sonicators	Focused ultra-sonicators	Multi Sample Sonicator
Instrument pricing
Consumables pricing
Range of applications
Scalable and sample volume flexibility
Throughput

Bioruptor ultrasonication for best results in:

✓ Chromatin shearing - Industry leader in accurate and tight fragment ranges

✓ DNA shearing - Excellent results for optimal fragment lengths in NGS library prep

✓ Protein aggregation studies - Standardizing seeding with the robust Bioruptor.
Read the app note by Dr. Kelvin Luk at the University of Pennsylvania “Standardizing seeding experiments using the Bioruptor® for the understanding of the neuronal alpha-synuclein pathology”

✓ 3D genome analysis with Hi-C - Preparing chromatin libraries with high-quality sonication.
Read the app note, “Unlock Low-Input 3D Genome Analysis with the Arima-HiC Kit”

✓ Mass spectrometry and increasing protein identification- Sample preparation using Preomics iST and Bioruptor sonication.
Read the app note “Increase your iST ultrasonication throughput with the new Bioruptor® Pico cartridge holder”

✓ Cell lysis, liposome prep, protein extraction, RNA extraction and more

✓ CUT&RUN –Sonication of input DNA (for enrichment comparison) for NGS

Products

Bioruptor^® Pico sonication device

The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing sam...

All-in-one solution
Highly reproducible
Processing of 6-16 samples
User friendly software
Five year warranty

Bioruptor^® Plus sonication device

The Bioruptor® uses a unique system to uniformely process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. The built-in cooling system...

Temperature-controlled
Easy to use
Processing of 3-12 samples
Sample size 100 µl – 20 ml
Advanced timing control

Bioruptor^® Pico sonication device

The Bioruptor® Pico (2013-2019) represented a breakthrough for shearing micro-volumes of 5 μl to larger volumes of up to 2 ml. The new&nbs...

Temperature-controlled
Easy to use
All-in-one solution
Processing of 6-16 samples
Sample size 5 µl – 2 ml
No soundproof box
Five year warranty

Bioruptor^® Pico accessories

C30010015

0.1 ml Bioruptor® Pico Microtubes
B01200041

0.1 ml tube holder & tube adaptors for Biorupto...
C30010020

0.2 ml microtubes for Bioruptor® Pico
C30010011

0.65 ml Bioruptor® Pico Microtubes
C30010016

1.5 ml Bioruptor® Pico Microtubes with Caps
C01020031

15 ml Bioruptor® Pico Tubes & sonication beads
C30010017

15 ml Bioruptor® Pico Tubes
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Bioruptor^® Plus (and Standard) accessories

C30010013

0.5 ml Bioruptor® Plus Microtubes
B01200043

0.5/0.65 ml tube holder for Bioruptor® Stan...
C30010010-300

1.5 ml Bioruptor® Plus TPX microtubes
C30010010-50

1.5 ml Bioruptor® Plus TPX microtubes
B01200011

1.5 ml tube holder for Bioruptor® Standard ...
C30010012-100

10 ml Bioruptor® Plus tubes
B01200012

10 ml tube holder for Bioruptor® Standard & Plus
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View more products from the Bioruptor^® Plus (and Standard) accessories product category.