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Shearing technologies

Bioruptor®

Best Workflow Practices for
ChIP-seq Analysis


Diagenode focuses on state-of-the-art preparation of high quality biological and chemical samples by developing the industry’s most advanced water bath sonicators and hydrodynamic devices. Our instruments are ideal for a number of applications in various fields of studies including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.

Technology explained

 

Reproductibility is our priority

reproductibility

An affordable instrument for wide range of applications

Designed for any researchers, the Bioruptor gives the user the right level of flexibility.

Bioruptor Cup Horn Sonicators Focused
ultra-sonicators		 Multi Sample Sonicator
Instrument pricing
Consumables pricing
Range of applications
Scalable and sample volume flexibility
Throughput

Bioruptor ultrasonication for best results in:

✓  Chromatin shearing - Industry leader in accurate and tight fragment ranges

✓  DNA shearing - Excellent results for optimal fragment lengths in NGS library prep

✓  Protein aggregation studies - Standardizing seeding with the robust Bioruptor.
Read the app note by Dr. Kelvin Luk at the University of Pennsylvania “Standardizing seeding experiments using the Bioruptor® for the understanding of the neuronal alpha-synuclein pathology”

✓  3D genome analysis with Hi-C - Preparing chromatin libraries with high-quality sonication.
Read the app note, “Unlock Low-Input 3D Genome Analysis with the Arima-HiC Kit”

✓  Mass spectrometry and increasing protein identification- Sample preparation using Preomics iST and Bioruptor sonication.
Read the app note “Increase your iST ultrasonication throughput with the new Bioruptor® Pico cartridge holder”

✓  Cell lysis, liposome prep, protein extraction, RNA extraction and more

Products

Bioruptor® Pico sonication device

Bioruptor Pico

The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing sam...

  • All-in-one solution
  • Highly reproducible
  • Processing of 6-16 samples
  • User friendly software
  • Five year warranty

Bioruptor® Plus sonication device

Bioruptor Plus Sonication Device

The Bioruptor® uses a unique system to uniformely process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. The built-in cooling system...

  • Temperature-controlled
  • Easy to use
  • Processing of 3-12 samples
  • Sample size 100 µl – 20 ml
  • Advanced timing control

Bioruptor® Pico sonication device

Bioruptor pico next gen sequencing

The Bioruptor® Pico (2013-2019) represented a breakthrough for shearing micro-volumes of 5 μl to larger volumes of up to 2 ml. The new&nbs...

  • Temperature-controlled
  • Easy to use
  • All-in-one solution
  • Processing of 6-16 samples
  • Sample size 5 µl – 2 ml
  • No soundproof box
  • Five year warranty

Bioruptor® Pico accessories


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    C30010015
    0.1 ml Bioruptor® Pico Microtubes
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    B01200041
    0.1 ml tube holder & tube adaptors for Biorupto...
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    C30010020
    0.2 ml microtubes for Bioruptor® Pico
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    C30010011
    0.65 ml Bioruptor® Pico Microtubes
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    C30010016
    1.5 ml Bioruptor® Pico Microtubes with Caps
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    C01020031
    15 ml Bioruptor® Pico Tubes & sonication beads
  • 15 ml tubes
    C30010017
    15 ml Bioruptor® Pico Tubes

  • View more

    View more products from the Bioruptor® Pico accessories product category.

Bioruptor® Plus (and Standard) accessories


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    C30010013
    0.5 ml Bioruptor® Plus Microtubes
  • Product image
    B01200043
    0.5/0.65 ml tube holder for Bioruptor® Stan...
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    C30010010-300
    1.5 ml Bioruptor® Plus TPX microtubes
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    C30010010-50
    1.5 ml Bioruptor® Plus TPX microtubes
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    B01200011
    1.5 ml tube holder for Bioruptor® Standard ...
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    C30010012-100
    10 ml Bioruptor® Plus tubes
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    B01200012
    10 ml tube holder for Bioruptor® Standard & Plus

  • View more

    View more products from the Bioruptor® Plus (and Standard) accessories product category.

Events

  • DNA methylation workshop: Become an expert at RRBS
    Diagenode
    Oct 1-Oct 31, 2021
  • Dutch Chromatin Meeting
    Radboud UMC, Geert Grooteplein 15, 6525 EZ Nijmegen, The Netherlands, Experience center, route 292 to 307
    Nov 12, 2021
 See all events

News

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The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.


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