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Bioruptor® Pico sonication device




All-in-one solution
Highly reproducible
Processing of 6-16 samples
User friendly software
Five year warranty
  •  Description
  •  Documents
  •  Related
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Catalog Number
Format
B01080010
1 unit

The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. Since 2004, Diagenode has accumulated shearing expertise to design the Bioruptor® Pico and guarantee the best experience with the sample preparation for number of applications -- in various fields of studies including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.

The Bioruptor Pico shearing accessories and consumables have been developed to allow flexibility in sample volumes (20 µl - 2 ml) and a fast parallel processing of samples (up to 16 samples simultaneously). The built-in cooling system (Bioruptor® Cooler) ensures high precision temperature control. The user-friendly interface has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. 

In addition, Diagenode provides fully-validated tubes that remain budget-friendly with low operating cost (< 1€/$/DNA sample) and shearing kits for best sample quality.

Application versatility:

  • DNA shearing for Next-Generation-Sequencing
  • Chromatin shearing
  • RNA shearing
  • Protein extraction from tissues and cells (also for mass spectrometry)
  • FFPE DNA extraction
  • Protein aggregation studies

  • Specifications
  • View accessories & consumables for Bioruptor® Pico

    Shearing Accessories

    Name Catalog number Throughput
    Tube holder for 0.2 ml tubes B01201144 16 samples
    Tube holder for 0.65 ml tubes B01201143 12 samples
    Tube holder for 1.5 ml tubes B01201140 6 samples
    15 ml sonication accessories B01200016 6 samples

    Shearing Consumables

    Name Catalog Number
    0.2 ml Pico Microtubes C30010020
    0.65 ml Pico Microtubes C30010011
    1.5 ml Pico Microtubes C30010016
    15 ml Pico Tubes C30010017
    15 ml Pico Tubes & sonication beads C01020031

    Find datasheet for Diagenode tubes here

  • Available shearing Kits

    Diagenode has optimized a range of solutions for successful chromatin preparation. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.

    For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.

    Kit choice guide

    SAMPLE TYPE SAMPLE INPUT KIT SDS
    CONCENTRATION
    NUCLEI
    ISOLATION
    CELLS
    < 100,000 Chromatin EasyShear Kit
    High SDS
    1%
    CELLS
    > 100,000 Chromatin EasyShear Kit
    Ultra Low SDS
    < 0.1%
    TISSUE
    Chromatin EasyShear Kit
    Ultra Low SDS
    < 0.1%
    PLANT TISSUE
    Chromatin EasyShear Kit
    for Plant
    0.5%
    FFPE SAMPLES
    Chromatin EasyShear Kit
    Low SDS
    0.2%
    CELLS
    Chromatin EasyShear Kit
    Low SDS
    0.2%
    TISSUE
    FFPE SAMPLES

    Guide for optimal chromatin preparation using Chromatin EasyShear Kits Read more

  •  Documents
    Bioruptor Pico Quickguide MANUAL
    Download
    Bioruptor Pico Manual MANUAL
    Download
    Bioruptor ® Sonicator Brochure BROCHURE
    Diagenode’s Bioruptor® uses state-of-the-art shearing device to disrupt, disp...
    Download
    Chromatin Shearing Guide PROTOCOL
    Guide for successful chromatin preparation using the Bioruptor Pico
    Download
    DNA shearing guide PROTOCOL
    DNA shearing for Next-Generation Sequencing with the Bioruptor Pico
    Download
    Which tubes for Bioruptor® Pico DOCUMENT
    Download
  •  Publications

    How to properly cite this product in your work

    Diagenode strongly recommends using this: Bioruptor® Pico sonication device (Diagenode Cat# B01080010). Click here to copy to clipboard.

    Using our products in your publication? Let us know!

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