Diagenode

ChIPmentation for high-quality and fast ChIP-seq library preparation

Diagenode’s ChIPmentation technology, based on tagmentation, enables the integration of library preparation during ChIP itself using transposase and sequencing-compatible adaptors. Unlike standard library preparation techniques that require multi-step ligation, ChIPmentation incorporates an easier and shorter protocol. Two versions of protocol have been validated: a manual procedure and an automated protocol on the IP-Star Compact Automated SystemThe combination of direct adaptor incorporation and automation allows for higher sensitivity from low cell numbers and reproducibility of results.

Benefits of the ChIPmentation system for optimal ChIP-seq

  • Ensure high quality data on low cell numbers and rare cell types
  • Save one full day from standard protocols in generating ChIP-seq libraries
  • Benefit from the elimination of sequencing adaptor dimers
  • Enjoy an easier protocol
  • Automate on the IP-Star® to support standardization and save time
Diagenode-ChIPmentation
In traditional ChIP-seq library preparation, the ligation of the adaptors is performed after chromatin immunoprecipitation, in three steps. In the Diagenode ChIPmentation workflow, not only are the adaptors directly incorporated during ChIP, but also the main steps are automated on the Diagenode IP-Star®. The combination of direct adaptor incorporation and automation allows for higher sensitivity from low cell numbers and reproducibility of results.

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Products

Cat. No.ProductFormatPrice
C01011000 Auto ChIPmentation Kit for Histones
This product must be used with the IP-Star Compact Automated System. Difficult and challenging histone ChIP-seq is now solved. Diagenode’s latest ...
24 rxns $2,320.00
C01011010 ChIPmentation Kit for Histones
Difficult and challenging histone ChIP-seq is now solved. Diagenode’s latest technology for histone ChIP-seq, ChIPmentation is a ligation-free, tag...
24 rxns $2,320.00

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