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Chromatin studies

Chromatin structure plays a key role in regulating gene expression by allowing DNA accessibility to transcriptional machinery and transcription factors. The packaging of DNA into nucleosomes forms a closed structure that is not highly accessible to transcriptional elements whereas the open nucleosome structure allows DNA to be accessible. Diagenode offers a number of solutions to help you analyze chromatin and the role of transcriptional machinery including ChIP kits, ChIPmentation kits, antibodies, pA-Tn5 and ATAC-seq kits.

The ChIP workflow

Products for chromatin study

  Crosslinking
Efficient solution for protein-protein fixation. Read more

  Chromatin shearing
Perfectly sheared chromatin is critical for ChIP success. 
Read more about solutions for successful chromatin preparation. 
Read more about Bioruptor sonication.

  Chromatin immunoprecipitation
Immunoprecipitation solutions for histone and transcription factor ChIP-qPCR and ChIP-seq for low inputs, plants, and animals including automated solutionsRead more

  ChIPmentation
ChIPmentation, an exclusive technology, is an end-to-end ChIP-seq solution for low and difficult inputs. Read more

  ChIP and ChIP-seq antibodies
ChIP-grade antibodies are essential for success. Learn more

  Primer pairs
Highly specific primer pairs for the amplification of the specific genomic regions. Read more

  DNA purification
Read more about solutions for DNA purification

  Library preparation for ChIP-seq
Optimized solutions for the library preparation from low DNA input. Read more

  ChIP and ChIP-seq automation
Reproducibility, optimization simplicity, no variability. Learn more

Chromatin resources

Posters

Application notes

Publications related to ChIP

Brochures

Products

Cat. No.ProductFormatPrice
C01080002 ATAC-seq kit
ATAC-seq, Assay for Transposase-Accessible Chromatin, followed by next generation sequencing, is a key technology for genome-wide mapping of access...
24 rxns $1,530.00

Chromatin shearing

Chromatin immunoprecipitation

ChIPmentation™

Cat. No.ProductFormatPrice
C01011032 24 SI for Tagmented libraries
The 24 SI for tagmented libraries includes 24 single primer indexes for multiplexing up to 24 samples. The primer indexes of the 24 SI Tagmented libraries ar...
24 SI $173.00
C01011011 µChIPmentation Kit for Histones
The Diagenode µChIPmentation Kit for Histones is optimized to perform ChIP-seq on as little as 10.000 cells from cell fixation to purified libraries....
24 rxns $2,193.00
C01011031 24 SI for ChIPmentation
Contact us The 24 SI for ChIPmentation includes 24 single primer indexes completing the TAG Kit for ChIPmentation. This set of indexes allows for...
24 indexes $173.00
C01011000 Auto ChIPmentation Kit for Histones - Replaced by C01011009
Contact us This product must be used with the IP-Star Compact Automated System. Diagenode’s latest technology for histone ChIP-seq, ...
24 rxns
C01011010 ChIPmentation Kit for Histones - Replaced by C01011009
Contact us Difficult and challenging histone ChIP-seq is now solved. Diagenode’s latest technology for histone ChIP-seq, ChIPmentation ...
24 rxns
C01011030 TAG Kit for ChIPmentation
Contact us Tagmentation is a reaction where an enzyme (a transposase) cleaves DNA and incorporates sequencing adaptors at the ends of the DNA fra...
24 rxns $969.00

CUT&Tag


  • default alt
    C01070001
    pA-Tn5 Transposase - loaded
  • default alt
    C01070002
    pA-Tn5 Transposase - unloaded
  • Mouse IgG
    C15410206
    Rabbit IgG

ATAC-seq


  • ATAC-seq kit
    C01080002
    ATAC-seq kit

Events

  • ChIP workshop
    Diagenode
    Sep 21-Sep 22, 2021
  • DNA methylation workshop: Master MeDIP assay
    Diagenode
    Sep 30, 2021
  • DNA methylation workshop: Become an expert at RRBS
    Diagenode
    Oct 1-Oct 31, 2021
 See all events

News

 See all news


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