|Chromatin shearing - Guide for successful chromatin preparation using the Bioruptor® Pico|
Chromatin immunoprecipitation (ChIP) is a common tool used to study protein-DNA interactions in c...
Cross-linking is typically achieved by using formaldehyde which forms reversible DNA-protein links.However, formaldehyde is usually not effective to cross-link proteins that are not directly bound to the DNA.So, for higher order and/or dynamic interactions, other cross-linkers should be considered for efficient protein-protein stabilization such as the Diagenode ChIP cross-link Gold. This reagent is to use in combination with formaldehyde.
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