CUT&Tag (Cleavage Under Targets and Tagmentation) is a technique for efficient chromatin profiling described in Kaya-Okur HS et al., Nature Commun. 2019. In CUT&Tag, proteins are first bound to chromatin by a specific antibody. This complex is then fused to a protein A-Tn5 transposase, loaded with sequencing adapters. Upon activation of the transposase, sequencing libraries can be easily and efficiently generated. Diagenode now offers the pA-Tn5 Transposase fusion protein for efficient CUT&Tag assays. Moreover, we have tested our ChIP-seq grade antibodies in CUT&Tag proving their high performance in this assay.

Products for CUT&Tag assay

Fusion protein

ChIP-seq grade antibodies

Negative CUT&Tag control

Sequencing indexes


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Diagenode’s Antibody Package for CUT&Tag (anti-rabbit) has been designed to be used with the iDeal CUT&Tag for Histones Kit. This package shoul...

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CUT&Tag-sequencing (Cleavage Under Targets and Tagmentation) is a new alternative method to ChIP-seq combining antibody-targeted controlled cleavage by a...

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pA-Tn5 transposase is a fusion protein of hyperactive Tn5 transposase and protein A developed for the CUT&Tag assay. For convenience, the fusion protein ...

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pA-Tn5 Transposase is a fusion protein of hyperactive Tn5 transposase and protein A developed for the CUT&Tag assay. For flexibility, the fusion protein ...

Mouse IgG

The negative Ctrl IgG from rabbit has been extensively validated in chromatin immunoprecipitation assays (ChIP). It contains a spectrum of the IgG subclasses...


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