Publications
Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.
Recurrent patterns of TOP1-mediated neuronal genomic damage shared ...
Published: July, 2026
Abstract: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer's disease (AD) represent two major categories of neurodegenerativ... Read more »
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Tagmentase
Published: July, 2026
Abstract: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer's disease (AD) represent two major categories of neurodegenerativ... Read more »
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Tagmentase
Endocardial TIE2 orchestrates cardiac trabeculation via sequesterin...
Published: June, 2026
Abstract: Abnormal cardiac trabeculation often leads to congenital heart disease (CHD). TIE2-ANG1 signaling is a key regulator of endocardial growth during t... Read more »
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iDeal ChIP-qPCR
Published: June, 2026
Abstract: Abnormal cardiac trabeculation often leads to congenital heart disease (CHD). TIE2-ANG1 signaling is a key regulator of endocardial growth during t... Read more »
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iDeal ChIP-qPCR
Transcriptional repression by TGIF2 coordinates neurogenic priming ...
Published: June, 2026
Abstract: Stem cells balance self-renewal with differentiation. Priming, i.e., low-level expression of differentiation-related genes, enables stem cells to r... Read more »
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Microplex Library Preparation kit
Published: June, 2026
Abstract: Stem cells balance self-renewal with differentiation. Priming, i.e., low-level expression of differentiation-related genes, enables stem cells to r... Read more »
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Microplex Library Preparation kit
Single-cell analyses identify the ginseng embryonic protoderm as a ...
Published: June, 2026
Abstract: Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside metabolites. However, the long cultivation cycle and susceptib... Read more »
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Universal Plant ChIP-seq Kit
Published: June, 2026
Abstract: Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside metabolites. However, the long cultivation cycle and susceptib... Read more »
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Universal Plant ChIP-seq Kit
ATRX inactivation disrupts global chromatin state and topology to d...
Published: June, 2026
Abstract: Mutational inactivation of the chromatin regulator gene ATRX (a-thalassemia mental retardation X-linked) represents a defining molecular abnormalit... Read more »
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Bioruptor Plus
Published: June, 2026
Abstract: Mutational inactivation of the chromatin regulator gene ATRX (a-thalassemia mental retardation X-linked) represents a defining molecular abnormalit... Read more »
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Bioruptor Plus
ZEB1 drives terminal erythroid maturation by controlling the GATA2-...
Published: June, 2026
Abstract: Erythropoiesis is a highly coordinated process governed by lineage-defining transcription factors. While several master regulators have been charac... Read more »
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Microplex Library Preparation kit
Published: June, 2026
Abstract: Erythropoiesis is a highly coordinated process governed by lineage-defining transcription factors. While several master regulators have been charac... Read more »
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Microplex Library Preparation kit
SIRT2 antagonizes MOF function during mitotic entry
Published: June, 2026
Abstract: Mitosis entry is tightly regulated by a complex network of mechanisms involving epigenetic modifications, signaling pathways, transcriptional contr... Read more »
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Antibody
Published: June, 2026
Abstract: Mitosis entry is tightly regulated by a complex network of mechanisms involving epigenetic modifications, signaling pathways, transcriptional contr... Read more »
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Antibody
Induced pluripotent stem cell-derived models of malignant nerve she...
Published: June, 2026
Abstract: Neurofibromatosis Type 1 (NF1) predisposes to peripheral nerve tumor development. The progression from a benign plexiform neurofibroma (PNF) toward... Read more »
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Chromatin Profiling (ChIP-seq) Services Infinium Human MethylationEPIC Array Service
Published: June, 2026
Abstract: Neurofibromatosis Type 1 (NF1) predisposes to peripheral nerve tumor development. The progression from a benign plexiform neurofibroma (PNF) toward... Read more »
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Chromatin Profiling (ChIP-seq) Services Infinium Human MethylationEPIC Array Service
Confined migration induces non-lethal DNA damage in developing neurons
Published: June, 2026
Abstract: Migratory cells tend to have soft nuclei that deform and penetrate narrow spaces1,2. Extensive nuclear deformation during migration can cause nucle... Read more »
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Tagmentase
Published: June, 2026
Abstract: Migratory cells tend to have soft nuclei that deform and penetrate narrow spaces1,2. Extensive nuclear deformation during migration can cause nucle... Read more »
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Tagmentase
Tau profiling of brain extracellular vesicles reveals PHF6 peptide ...
Published: June, 2026
Abstract: Background Tauopathies are neurodegenerative diseases all characterized by tau lesions in the brain. Nevertheless, a clinical and pathophysiologic... Read more »
Published: June, 2026
Abstract: Background Tauopathies are neurodegenerative diseases all characterized by tau lesions in the brain. Nevertheless, a clinical and pathophysiologic... Read more »
An automated workflow for quantifying the formation of synuclein ag...
Published: June, 2026
Abstract: Parkinson's disease (PD) is a neurodegenerative disorder characterized by alpha-synuclein (α-syn) aggregates termed Lewy bodies. To model PD pathol... Read more »
Published: June, 2026
Abstract: Parkinson's disease (PD) is a neurodegenerative disorder characterized by alpha-synuclein (α-syn) aggregates termed Lewy bodies. To model PD pathol... Read more »
An expanded metabolic pathway for androgen production by commensal ...
Published: June, 2026
Abstract: Commensal bacteria have been implicated in the modulation of steroid hormones, including circulating androgen levels in the host. However, the micr... Read more »
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Megaruptor
Published: June, 2026
Abstract: Commensal bacteria have been implicated in the modulation of steroid hormones, including circulating androgen levels in the host. However, the micr... Read more »
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Megaruptor
A spatial multi-omics atlas of immunosenescence reveals germinal-ce...
Published: June, 2026
Abstract: Immunosenescence is a hallmark of human aging and contributes to age-related immune decline, yet the development of senescence-associated phenotype... Read more »
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Tagmentase
Published: June, 2026
Abstract: Immunosenescence is a hallmark of human aging and contributes to age-related immune decline, yet the development of senescence-associated phenotype... Read more »
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Tagmentase
Sustained PRC1.1 activity preserves gene repression independently o...
Published: June, 2026
Abstract: Loss-of-function mutations in BCOR, a subunit of the non-canonical Polycomb Repressive Complex 1.1 (PRC1.1), are frequently observed in acute myelo... Read more »
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Antibody
Published: June, 2026
Abstract: Loss-of-function mutations in BCOR, a subunit of the non-canonical Polycomb Repressive Complex 1.1 (PRC1.1), are frequently observed in acute myelo... Read more »
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Antibody
An active Helitron transposon family in wheat
Published: June, 2026
Abstract: Transposable elements play a pivotal role in genome evolution and phenotypic variation in numerous eukaryotic species. Helitrons, a recently identi... Read more »
Published: June, 2026
Abstract: Transposable elements play a pivotal role in genome evolution and phenotypic variation in numerous eukaryotic species. Helitrons, a recently identi... Read more »
A Fetal Fraction Optimized 106-Plex Digital PCR Assay for Non-Invas...
Published: May, 2026
Abstract: Background/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal f... Read more »
Published: May, 2026
Abstract: Background/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal f... Read more »
New mechanistic insights from alignment of accessible chromatin and...
Published: May, 2026
Abstract: Genome-wide association studies for kidney function identified hundreds of genomic signals overlapping non-coding regions. Prioritizing regulated t... Read more »
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CUT&Tag
Published: May, 2026
Abstract: Genome-wide association studies for kidney function identified hundreds of genomic signals overlapping non-coding regions. Prioritizing regulated t... Read more »
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CUT&Tag
A scalable Tn5-based method for genome-wide DNA methylation profili...
Published: May, 2026
Abstract: DNA methylation is a key epigenetic modification involved in development and disease, including cancer, and serves as a biomarker for diagnosis. Cu... Read more »
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Antibody
Published: May, 2026
Abstract: DNA methylation is a key epigenetic modification involved in development and disease, including cancer, and serves as a biomarker for diagnosis. Cu... Read more »
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Antibody
Gut microbiome components predict response to neoadjuvant short-cou...
Published: May, 2026
Abstract: Background Although the gut microbiome shapes responses to anti-tumor immunotherapy and chemotherapy, its predictive value for neoadjuvant short-c... Read more »
Published: May, 2026
Abstract: Background Although the gut microbiome shapes responses to anti-tumor immunotherapy and chemotherapy, its predictive value for neoadjuvant short-c... Read more »
Molecular profiling of alpha-synuclein pathology and seeding activi...
Published: May, 2026
Abstract: Parkinson’s disease (PD) is neuropathologically characterized by the abnormal accumulation of fibrillar alpha-synuclein (aSyn) within selectively v... Read more »
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Bioruptor Plus
Published: May, 2026
Abstract: Parkinson’s disease (PD) is neuropathologically characterized by the abnormal accumulation of fibrillar alpha-synuclein (aSyn) within selectively v... Read more »
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Bioruptor Plus
Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a no...
Published: May, 2026
Abstract: Glycoprotein nonmetastatic melanoma B (GPNMB) is critical to cellular uptake of pathological forms of alpha-synuclein (aSyn), the hallmark disease ... Read more »
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Bioruptor Plus
Published: May, 2026
Abstract: Glycoprotein nonmetastatic melanoma B (GPNMB) is critical to cellular uptake of pathological forms of alpha-synuclein (aSyn), the hallmark disease ... Read more »
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Bioruptor Plus
Convergent evolution of intestinal lineages in the phylum Methanoba...
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
Pervasive and programmed nucleosome distortion on single chromatin ...
Published: April, 2026
Abstract: Despite decades of biochemical and structural studies of the nucleosome, researchers lack genome-scale methods to determine variability in nucleoso... Read more »
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Megaruptor
Published: April, 2026
Abstract: Despite decades of biochemical and structural studies of the nucleosome, researchers lack genome-scale methods to determine variability in nucleoso... Read more »
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Megaruptor
Atomic structures of medin and Aβ fibrils reveal polymorphic remode...
Published: April, 2026
Abstract: Amyloid assembly in vivo occurs in complex environments where multiple aggregation-prone species coexist. Aβ and medin are prevalent amyloids in ag... Read more »
Published: April, 2026
Abstract: Amyloid assembly in vivo occurs in complex environments where multiple aggregation-prone species coexist. Aβ and medin are prevalent amyloids in ag... Read more »
MeCP2 gene dosage-dependent neurodevelopmentally restricted defects...
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Exploring tear biomarkers with shotgun proteomics for retinoblastom...
Published: April, 2026
Abstract: The most common ocular neoplasia among children is retinoblastoma. Currently, the diagnosis of this disease is essentially clinical, taking a biops... Read more »
Published: April, 2026
Abstract: The most common ocular neoplasia among children is retinoblastoma. Currently, the diagnosis of this disease is essentially clinical, taking a biops... Read more »
Oxidative stress causes a reversible decrease of deubiquitylases ac...
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinosit...
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
TGF-β/SMAD4/14-3-3σ/TFEB axis promotes mesenchymal-epithelial trans...
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Population differences of chromosome 22q11.2 duplication structure ...
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor