Publications,References

SUMO protease FUG1, histone reader AL3 and the PRC1 Complex areinte...
Published: December, 2023

Abstract: Epigenetic gene silencing induced by expanded repeats can cause diverse phenotypes ranging from severe growth defects in plants to genetic diseases... Read more »

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Antibody

Landscape of prostate-specific membrane antigen heterogeneity and r...
Published: April, 2023

Abstract: Tumor expression of prostate-specific membrane antigen (PSMA) is lost in 15-20\% of men with castration-resistant prostate cancer (CRPC), yet the u... Read more »

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Epigenetic modifier alpha-ketoglutarate modulates aberrant gene bod...
Published: April, 2023

Abstract: BACKGROUND: Diabetic cardiomyopathy (DCM) is a leading cause of death in diabetic patients. Hyperglycemic myocardial microenvironment significantly... Read more »

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Comprehensive epigenomic profiling reveals the extent of disease-sp...
Published: April, 2023

Abstract: Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis characterized by enthesitis of the spine and sacroiliac joints. Ge... Read more »

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Li-Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes T...
Published: April, 2023

Abstract: UNLABELLED: Cancer-relevant mutations in the oligomerization domain (OD) of the p53 tumor suppressor protein, unlike those in the DNA binding domai... Read more »

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Spatial epigenome-transcriptome co-profiling of mammalian tissues.
Published: April, 2023

Abstract: Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular sta... Read more »

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Transient suppression of SUMOylation in embryonic stem cells genera...
Published: April, 2023

Abstract: Recent advances in synthetic embryology have opened new avenues for understanding the complex events controlling mammalian peri-implantation develo... Read more »

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A kinesin-based approach for inducing chromosome-specific mis-segre...
Published: April, 2023

Abstract: Various cancer types exhibit characteristic and recurrent aneuploidy patterns. The origins of these cancer type-specific karyotypes are still unkno... Read more »

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Farrerol directly activates the deubiqutinase UCHL3 to promote DNA ...
Published: April, 2023

Abstract: Farrerol, a natural flavanone, promotes homologous recombination (HR) repair to improve genome-editing efficiency, but the specific protein that fa... Read more »

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Sperm DNA methylation is predominantly stable in mice offspring bor...
Published: April, 2023

Abstract: BACKGROUND: Spermatogonial stem cell transplantation (SSCT) is proposed as a fertility therapy for childhood cancer survivors. SSCT starts with cry... Read more »

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The Effect of Metformin and Carbohydrate-Controlled Diet on DNA Met...
Published: April, 2023

Abstract: Polycystic ovary syndrome (PCOS) is an endocrine disease associated with infertility and metabolic disorders in reproductive-aged women. In this st... Read more »

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RNA landscapes of brain tissue and brain tissue-derived extracellul...
Published: April, 2023

Abstract: Antiretroviral treatment regimens can effectively control HIV replication and some aspects of disease progression. However, molecular events in end... Read more »

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Distinct regulation of EZH2 and its repressive H3K27me3 mark in Pol...
Published: April, 2023

Abstract: Merkel cell carcinoma (MCC) is an aggressive skin cancer for which Merkel cell polyomavirus (MCPyV) integration and expression of viral oncogenes s... Read more »

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A genome sequence for Biomphalaria pfeifferi, the major vector snai...
Published: March, 2023

Abstract: BACKGROUND: Biomphalaria pfeifferi is the world's most widely distributed and commonly implicated vector snail species for the causative agent of h... Read more »

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The genome sequence of the Lime-speck Pug, Eupithecia centaureata (...
Published: March, 2023

Abstract: We present a genome assembly from an individual male Eupithecia centaureata (the Lime-speck Pug; Arthropoda; Insect; Lepidoptera; Geometridae). The... Read more »

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Analyzing genomic and epigenetic profiles in single cells by hybrid...
Published: March, 2023

Abstract: scGET-seq simultaneously profiles euchromatin and heterochromatin. scGET-seq exploits the concurrent action of transposase Tn5 and its hybrid form ... Read more »

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Tagmentase

The genome sequence of the Early Bumblebee, Bombus pratorum (Linnae...
Published: March, 2023

Abstract: We present a genome assembly from an individual female Bombus pratorum (the Early Bumblebee; Arthropoda; Insecta; Hymenoptera; Apidae). The genome ... Read more »

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The genome sequence of the Golden-tailed Leafwalker, Xylota sylvaru...
Published: March, 2023

Abstract: We present a genome assembly from an individual male Xylota sylvarum (the Golden-tailed Leafwalker; Arthropoda; Insecta; Diptera; Syrphidae). The g... Read more »

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DNA methylation changes from primary cultures through senescence-by...
Published: March, 2023

Abstract: Current chemical testing strategies are limited in their ability to detect non-genotoxic carcinogens (NGTxC). Epigenetic anomalies develop during c... Read more »

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Premium RRBS Kit

A highly-contiguous and annotated genome assembly of the Lesser Pra...
Published: March, 2023

Abstract: The Lesser Prairie-Chicken (Tympanuchus pallidicinctus; LEPC) is an iconic North American prairie grouse, renowned for ornate and spectacular breed... Read more »

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Chromatin profiling identifies transcriptional readthrough as a con...
Published: March, 2023

Abstract: The piRNA pathway in mosquitoes differs substantially from other model organisms, with an expanded PIWI gene family and functions in antiviral defe... Read more »

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Antibody

The genome sequence of the Ruby Tiger, Phragmatobia fuliginosa (Lin...
Published: March, 2023

Abstract: We present a genome assembly from an individual male Phragmatobia fuliginosa (the Ruby Tiger; Arthropoda; Insecta; Lepidoptera; Erebidae). The geno... Read more »

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Epigenetic dosage identifies two major and functionally distinct be...
Published: March, 2023

Abstract: The mechanisms that specify and stabilize cell subtypes remain poorly understood. Here, we identify two major subtypes of pancreatic Î² ... Read more »

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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones

The genome sequence of the White-shouldered Marble, Apotomis turbid...
Published: March, 2023

Abstract: We present a genome assembly from an individual male Apotomis turbidana (the White-shouldered Marble; Arthropoda; Insecta; Lepidoptera; Tortricidae... Read more »

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Altered DNA methylation and gene expression predict disease severit...
Published: March, 2023

Abstract: Aicardi-Goutières Syndrome (AGS) is a rare neuro-inflammatory disease characterized by increased expression of interferon-stimulated genes (... Read more »

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Infinium Human MethylationEPIC Array Service

Comprehensive molecular phenotyping of -deficient gastric cancer re...
Published: March, 2023

Abstract: OBJECTIVE: Gastric cancer (GC) is a leading cause of cancer mortality, with being the second most frequently mutated driver gene in GC. We sought t... Read more »

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Antibody

Single substitution in H3.3G34 alters DNMT3A recruitment to causepr...
Published: March, 2023

Abstract: Germline histone H3.3 amino acid substitutions, including H3.3G34R/V, cause severe neurodevelopmental syndromes. To understand how these mutations ... Read more »

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Antibody

Synthetic maize centromeres transmit chromosomes across generations.
Published: March, 2023

Abstract: Centromeres are long, often repetitive regions of genomes that bind kinetochore proteins and ensure normal chromosome segregation. Engineering cent... Read more »

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ChIP-qPCR

The RNA m5C Methylase NSUN2 Modulates Corneal EpithelialWound Healing.
Published: March, 2023

Abstract: PURPOSE: The emerging epitranscriptomics offers insights into the physiopathological roles of various RNA modifications. The RNA methylase NOP2/Sun... Read more »

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Antibody

Pre-diagnosis plasma cell-free DNA methylome profiling up to seveny...
Published: February, 2023

Abstract: Profiling of cell-free DNA (cfDNA) has been well demonstrated to be a potential non-invasive screening tool for early cancer detection. However, li... Read more »

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