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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

chromIDEAS reveals epigenetic dynamics via multi-dimensional cluste...
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Exon inclusion signatures enable accurate estimation of splicing fa...
Published: March, 2026
Abstract: Splicing factors control exon inclusion in messenger RNAs, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by m... Read more »
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Bioruptor Plus
SIRT1 mediates brain metabolic and developmental consequences of me...
Published: February, 2026
Abstract: Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological d... Read more »
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Premium RRBS Kit
Hypoxic stress granules trigger immunogenic dormancy in lung cancer
Published: February, 2026
Abstract: Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for eff... Read more »
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Antibody
HIF sustain a transcriptional regulatory circuit of EPAS1 expressio...
Published: February, 2026
Abstract: Initiation and sustainment of oncogenic signaling is a hallmark of cancer evolution and progression. In renal clear cell carcinoma, loss of von... Read more »
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CUT&Tag
Comparative multi-omics of the macrophage response to infection wit...
Published: February, 2026
Abstract: Background Bovine tuberculosis (bTB) is a chronic infectious disease primarily caused by Mycobacterium bovis, which inflicts significan... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services
Non-disruptive in vitro monitoring of cellular states with cell-fre...
Published: February, 2026
Abstract: Individual CpG methylation signatures characterize each mammalian cell type, thereby offering a powerful readout for clinical and diagnostic applic... Read more »
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Megaruptor
Acute NIPBL depletion reveals in vivo dynamics of loop extrusion an...
Published: February, 2026
Abstract: The organization of the genome in three-dimensional space is highly dynamic, yet how these dynamics are regulated and the role they play in gen... Read more »
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Microplex Library Preparation kit
Ononin Sensitizes Papillary Thyroid Carcinoma Cells to Cisplatin by...
Published: February, 2026
Abstract: Ononin, a natural isoflavone glycoside, has demonstrated antitumor activity in several malignancies, but its role in papillary thyroid carcinoma ... Read more »
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iDeal ChIP-qPCR
Higher order repeat structures reflect diverging evolutionary paths...
Published: February, 2026
Abstract: Background: Highly repetitive tandem repeat arrays, known as satellite DNAs, are enriched in low-recombination regions such as centromeres. Sa... Read more »
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Megaruptor
High-quality genome sequence of five Antarctic actinomycetes: Micro...
Published: February, 2026
Abstract: Micromonospora ureilytica DSM 120150, Nocardiopsis akebiae DSM 120151, Streptomyces fildesensis DSM 41987T, Streptomy... Read more »
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Megaruptor
Microglia-Derived Extracellular Vesicles from Alzheimer's Disease P...
Published: February, 2026
Abstract: Alzheimer's disease (AD) represents the most common cause of dementia and urgently requires sensitive biomarkers and effective therapies. Extrace... Read more »
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D-Plex small RNA-seq
CUT homeobox factors modulate chromatin accessibility in neurons
Published: February, 2026
Abstract: Abstract Neuronal identity relies on coordinated transcriptional programs that include both neuron type-specific features and broadly shared pan-n... Read more »
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Tagmentase
Unbalanced chromatin binding of Polycomb complexes drives neurodeve...
Published: February, 2026
Abstract: Abstract The prevalence of neurodevelopmental disorders (NDDs) in children is increasing, yet their underlying causes remain largely unknown. We... Read more »
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ChIP Cross-link Gold
Comparison with Ezh2 reveals the PRC2-dependent functions of Jarid2...
Published: February, 2026
Abstract: Abstract Previous studies showed the polycomb repressive complex 2 (PRC2) co-factor Jarid2 represses self-renewal transcriptional networks in mo... Read more »
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CUT&Tag
ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion...
Published: February, 2026
Abstract: Abstract ZFTA-RELA+ ependymomas are malignant brain tumours defined by fusions formed between the putative chromatin remodeller ZFTA and th... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors
HIV Infection as an Independent Factor Accelerating Epigenetic Agei...
Published: February, 2026
Abstract: Abstract A number of published studies suggest that HIV infection accelerates epigenetic ageing. The main aim of this study was to ascertain if HI... Read more »
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MagMeDIP kit
Proteomic profiling of UV damage repair patches uncovers histone ch...
Published: January, 2026
Abstract: DNA damage compromises not only genome stability but also chromatin integrity, which plays a central role in controlling cell identity. Chromatin r... Read more »
Using the linear references from the pangenome to discover missing ...
Published: January, 2026
Abstract: To better understand large-effect pathogenic variation associated with autism, we generated long-read sequencing (LRS) data to construct phased and... Read more »
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Megaruptor
SPRED2 suppresses the stemness of hepatocellular carcinoma through ...
Published: January, 2026
Abstract: Abstract Objective: We previously reported that endogenous Sprouty-related, EVH1 domain-containing protein 2 (SPRED2), an inhibitor of the ... Read more »
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iDeal ChIP-qPCR
Genomic Validation of PERV‐C‐Free Pigs to Support Xenotransplantation
Published: January, 2026
Abstract: Porcine endogenous retroviruses (PERVs) are present in the germ lines of domesticated pigs (Sus scrofa) and related suids. There are three types of... Read more »
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Megaruptor
Molecular profiling of chemotherapy-resistant breast cancer reveals...
Published: January, 2026
Abstract: Aims Chemotherapy resistance remains a major challenge in breast cancer (BC) treatment. This study aimed to investigate the role of DNA methylat... Read more »
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Infinium Human MethylationEPIC Array Service
Impairment in stimulus-response learning as a cognitive biomarker i...
Published: January, 2026
Abstract: Translating findings from preclinical assessments of cognitive function relevant to synucleinopathies into successful clinical trials poses signifi... Read more »
Structural variations in evolutionary novel genomic regions: new in...
Published: January, 2026
Abstract: Background Neurodevelopmental disorders (NDDs) are highly diverse conditions often associated with genetic abnormalities. However, a large numbe... Read more »
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Megaruptor
Multimodal epigenetic and enhancer network remodeling shape the tra...
Published: January, 2026
Abstract: Epigenetic regulation is a key determinant of adipocyte fate, driving the differentiation toward white or thermogenic beige phenotypes in respo... Read more »
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Antibody Microplex Library Preparation kit
Multimodal epigenetic and enhancer network remodeling shape the tra...
Published: January, 2026
Abstract: Abstract Epigenetic regulation is a key determinant of adipocyte fate, driving the differentiation toward white or thermogenic beige phenotypes in... Read more »
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Antibody Microplex Library Preparation kit
CRISPR-based precise methylation of specific FUT8 promoter regions ...
Published: January, 2026
Abstract: A major advantage of producing therapeutic proteins in mammalian cells is their ability to tailor proteins with human-like posttranslational modi... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Refining a mouse model of progressive supranuclear palsy through in...
Published: January, 2026
Abstract: Objective A major obstacle to developing effective therapies for Progressive Supranuclear Palsy (PSP), a uniformly fatal 4R tauopathy, is the ab... Read more »
Targeting transthyretin by one Cas9 variant with superfidelity and ...
Published: January, 2026
Abstract: Amyloid transthyretin (ATTR) amyloidosis is a fatal disease caused by the accumulation of misfolded transthyretin proteins. Although knocking down ... Read more »
The Peripheral Epigenome Predicts White Matter Volume Contingent on...
Published: December, 2025
Abstract: White matter (WM) development is crucial for efficient neural connectivity, and disruptions in its maturation are associated with neurocognitive an... Read more »
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Infinium Human MethylationEPIC Array Service

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