Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Effects of GSK-J4 on JMJD3 Histone Demethylase in Mouse Prostate Ca...
Published: May, 2022

Abstract: Background/aim: Histone methylation status is required to control gene expression. H3K27me3 is an epigenetic tri-methylation modification to h... Read more »

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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
Epigenetic Mechanisms Mediating Cell State Transitions in Chondrocytes
Published: May, 2022

Abstract: Epigenetic modifications play critical roles in regulating cell lineage differentiation, but the epigenetic mechanisms guiding specific differentia... Read more »

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Bioruptor Antibody Microplex Library Preparation kit True MicroChIP kit
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesi...
Published: April, 2022

Abstract: People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and major depressive disorder (... Read more »

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D-Plex small RNA-seq
AUXIN RESPONSE FACTOR 16 (StARF16) regulates defense gene StNPR1 up...
Published: April, 2022

Abstract: We demonstrate a new regulatory mechanism in the jasmonic acid (JA) and salicylic acid (SA) mediated crosstalk in potato defense response, wherein,... Read more »

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Antibody Universal Plant ChIP-seq Kit
CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enha...
Published: March, 2022

Abstract: Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but s... Read more »

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IP-Star Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS C...
Published: February, 2022

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »

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Chromatin Profiling (ChIP-seq) Services
Comprehensive characterization of the epigenetic landscape in Multi...
Published: January, 2022

Abstract: Background: Human multiple myeloma (MM) cell lines (HMCLs) have been widely used to understand themolecular processes that drive MM biology. Epigen... Read more »

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Antibody Bioruptor Plus IPure kit IP-Star Compact
Single cell quantification of ribosome occupancy in early mouse dev...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq
Cancer Detection and Classification by CpG Island Hypermethylation ...
Published: November, 2021

Abstract: Cell-free DNA (cfDNA) methylation has emerged as a promising biomarker for early cancer detection, tumor type classification, and treatment respons... Read more »

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MethylCap kit
ATRX regulates glial identity and the tumor microenvironment in IDH...
Published: November, 2021

Abstract: Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent... Read more »

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CUT&Tag
The ETS transcription factor ERF controls the exit from the naïve p...
Published: October, 2021

Abstract: The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this ... Read more »

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Premium RRBS Kit DNA Methylation
Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Ne...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service) DNA Methylation
Genome-wide epigenomic analyses in patients with nociceptive and ne...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

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DNA Methylation Profiling (RRBS Service)
Functional microRNA targetome undergoes degeneration-induced shift ...
Published: August, 2021

Abstract: Background: MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular... Read more »

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D-Plex small RNA-seq
Environmental enrichment preserves a young DNA methylation landscap...
Published: June, 2021

Abstract: The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve br... Read more »
Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Le...
Published: June, 2021

Abstract: Dyskinesias are characterized by abnormal repetitive involuntary movements due to dysfunctional neuronal activity. Although levodopa-induced dyskin... Read more »

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Premium RRBS Kit
Therapy-induced DNA methylation inactivates MCT1 and renders tumor ...
Published: June, 2021

Abstract: Metabolic plasticity in cancer cells makes use of metabolism-targeting agents very challenging. Drug-induced metabolic rewiring may, however, uncov... Read more »

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DNA Methylation Methylated DNA immunoprecipitation MagMeDIP qPCR Kit
ChIP-seq protocol for sperm cells and embryos to assess environment...
Published: June, 2021

Abstract: In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descend... Read more »

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Antibody
Familial thrombocytopenia due to a complex structural variant resul...
Published: June, 2021

Abstract: Advances in genome sequencing have resulted in the identification of the causes for numerous rare diseases. However, many cases remain unsolved wit... Read more »

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Megaruptor
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of...
Published: May, 2021

Abstract: Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely repor... Read more »

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Tagmentase
Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors
Published: May, 2021

Abstract: Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Semi... Read more »

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D-Plex small RNA-seq
Vesicle-bound regulatory RNAs are associated with tissue aging
Published: May, 2021

Abstract: Previous work on murine models and human demonstrated global as well as tissue-specific molecular aging trajectories in solid tissues and body flui... Read more »

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D-Plex RNA-seq kit
HOTAIR lncRNA promotes epithelial-mesenchymal transition byredistri...
Published: May, 2021

Abstract: Epithelial-to-mesenchymal transition (EMT) describes the loss of epithelial traits and gain of mesenchymal traits by normal cells during developmen... Read more »

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Antibody
The lncRNA and the transcription factor WRKY42 target common cell ...
Published: May, 2021

Abstract: Plant long noncoding RNAs (lncRNAs) are key chromatin dynamics regulators, directing the transcriptional programs driving a wide variety of develop... Read more »

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Antibody
Placental uptake and metabolism of 25(OH)Vitamin D determines itsac...
Published: May, 2021

Abstract: Pregnancy 25-hydroxyvitamin D (25(OH)D) concentrations are associated with maternal and fetal health outcomes, but the underlying mechanisms have n... Read more »

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Antibody
Chromatin accessibility governs the differential response of cancer...
Published: May, 2021

Abstract: Depleting the microenvironment of important nutrients such as arginine is a key strategy for immune evasion by cancer cells. Many tumors overexpres... Read more »

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Antibody
Sarcomere function activates a p53-dependent DNA damage response th...
Published: May, 2021

Abstract: Human cardiac regeneration is limited by low cardiomyocyte replicative rates and progressive polyploidization by unclear mechanisms. To study this ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Published: May, 2021

Abstract: Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to so... Read more »

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Antibody
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at ...
Published: April, 2021

Abstract: Analyzing all features of small non-coding RNA sequencing data can be demanding and challenging. To facilitate this process, we developed miRMaster... Read more »

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small non-coding RNA sequencing analysis microRNA miRNA prediction bioinformatic tools D-Plex RNA-seq kit
Enhanced cell deconvolution of peripheral blood using DNA methylati...
Published: April, 2021

Abstract: DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution ... Read more »

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DNA methylation microarray Immune profiling

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