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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Unified molecular approach for spatial epigenome, transcriptome, an...
Published: April, 2025
Abstract: Spatial epigenomics and multiomics can provide fine-grained insights into cellular states but their widespread adoption is limited by the requireme... Read more »
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Tagmentase
Complete sequencing of ape genomes
Published: April, 2025
Abstract: The most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our ... Read more »
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Megaruptor
Menin-MLL1 complex cooperates with NF-Y to promote HCC survival
Published: April, 2025
Abstract: Abstract Identification of new therapeutic targets in hepatocellular carcinoma (HCC) remains critical. Chromatin regulating complexes are frequent... Read more »
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Tagmentase
Embryo-scale single-cell chemical transcriptomics reveals dependenc...
Published: April, 2025
Abstract: Summary Organogenesis is a highly organized process that is conserved across vertebrates and is heavily dependent on intercellular signaling to ac... Read more »
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Tagmentase
Repression of oxidative phosphorylation by NR2F2, MTERF3 and GDF15 ...
Published: March, 2025
Abstract: Lifestyle factors such as a Western diet or metabolic diseases like diabetes disrupt glucose homeostasis and induce stress responses, yet their imp... Read more »
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ATAC-seq
SIRT6 activator fucoidan extends healthspan and lifespan in aged wi...
Published: March, 2025
Abstract: Abstract SIRT6 is a protein deacylase, deacetylase, and mono-ADP-ribosylase (mADPr) regulating biological pathways important for longevity includi... Read more »
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Tagmentase
HSV-1 infection induces a downstream shift of the +1 nucleosome
Published: March, 2025
Abstract: Herpes simplex virus 1 (HSV-1) infection induces a loss of host transcriptional activity and widespread disruption of host transcription terminatio... Read more »
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Antibody
Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in reg...
Published: March, 2025
Abstract: The histone chaperone and transcription elongation factor SPT6 is integral to RNA polymerase II (RNAPII) activity. SPT6 also plays a crucial role i... Read more »
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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ...
Published: March, 2025
Abstract: Microglial diversity arises from the interplay between inherent genetic programs and external environmental signals. However, the mechanisms by whi... Read more »
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iDeal ChIP-seq Kit for Histones
Spatially resolved genome-wide joint profiling of epigenome and tra...
Published: March, 2025
Abstract: The epigenome of a cell is tightly correlated with gene transcription, which controls cell identity and diverse biological activities. Recent advan... Read more »
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Tagmentase CUT&Tag
Cortico-striatal circuit mechanisms drive the effects of D1 dopamin...
Published: March, 2025
Abstract: Working memory capacity (WMC), the number of items remembered in a short-time interval, is regulated by fronto-striatal dopamine (DA) and is re... Read more »
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Bioruptor
Multi-step genomics on single cells and live cultures in sub-nanoli...
Published: March, 2025
Abstract: Abstract Single-cell genomics encompasses a set of methods whereby hundreds to millions of cells are individually subjected to multiplexed assays ... Read more »
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Tagmentase
Transcriptional stress induces the overexpression of novel lncRNAs ...
Published: March, 2025
Abstract: Long non-coding RNAs (lncRNAs) have been shown to play a role during transcriptional regulation in response to stress. However, their function unde... Read more »
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CRISPR
Activin A activation of Smad3 mitigates innate inflammation in mous...
Published: March, 2025
Abstract: Phosphorylation of Smad3 is a critical mediator of TGF-β signaling, which plays an important role in regulating innate immune responses. Howev... Read more »
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iDeal ChIP-qPCR
In vivo prime editing rescues photoreceptor degeneration in nonsens...
Published: March, 2025
Abstract: The next-generation gene editing tool, prime editing (PE), is adept at correcting point mutations precisely with high editing efficiency and rare o... Read more »
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Bioruptor
ZEB1 transcription factor induces tumor cell PD-L1 expression in me...
Published: March, 2025
Abstract: Tumor cells can evade antitumor immune response by expressing the PD-L1 ligand, leading to the inhibition of PD-1-expressing T lymphocytes. The mec... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
IER3: exploring its dual function as an oncogene and tumor suppressor
Published: March, 2025
Abstract: The IER3 gene has a complex role in cancer biology, acting either as a tumor suppressor or an oncogene, depending on the cancer type. This duality ... Read more »
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iDeal ChIP-seq Kit for Histones
Recurrent patterns of widespread neuronal genomic damage shared by ...
Published: March, 2025
Abstract: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer's disease (AD) are common neurodegenerative disorders for which t... Read more »
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Tagmentase
Distinct molecular mechanisms of stress habituation in the mouse hi...
Published: March, 2025
Abstract: Chronic stress is a risk factor for neuropsychiatric disorders, making the ability to adapt to repeated stress a crucial determinant of mental heal... Read more »
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Tagmentase
Extracellular Vesicles From Follicular Fluid in Infertile Women: Si...
Published: March, 2025
Abstract: The declining birth rates and fertility challenges in Europe have intensified global concerns over rising infertility, particularly among women. Th... Read more »
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D-Plex small RNA-seq
Comprehensive molecular portrait reveals genetic diversity and dist...
Published: March, 2025
Abstract: Small intestinal neuroendocrine tumors (siNETs) are rare bowel tumors arising from malignant enteroendocrine cells, which normally regulate digesti... Read more »
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Infinium Human MethylationEPIC Array Service
Diverse somatic genomic alterations in single neurons in chronic tr...
Published: March, 2025
Abstract: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that is linked to exposure to repetitive head impacts (RHI), yet little is kn... Read more »
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Tagmentase
Clinical Value of MLPA for Prognostic Assessment of Chromosomal Rea...
Published: March, 2025
Abstract: Purpose: Uveal melanoma (UM) is the most prevalent primary intraocular malignancy in adults, with prognosis significantly influenced by geneti... Read more »
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Infinium Human MethylationEPIC Array Service
Differences in maternal diet fiber content influence patterns of ge...
Published: March, 2025
Abstract: This study investigates the impact of maternal gestation diets with varying fiber contents on gene expression and chromatin accessibility in fetuse... Read more »
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ATAC-seq
A highly accurate nanopore-based sequencing workflow for culture an...
Published: February, 2025
Abstract: Background The application of molecular sequencing methods for microbiome profiling of biological samples are largely restricted to research u... Read more »
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Bioruptor
H2AJ Is a Direct Androgen Receptor Target Gene That Regulates Andro...
Published: February, 2025
Abstract: Background: Prostate cancer (PCa) is a significant public health issue, particularly in developed countries. The androgen receptor (AR) plays ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Epigenetic regulation of visual system remodeling during flatfish m...
Published: February, 2025
Abstract: Flatfish metamorphosis is characterized by extensive tissue remodeling, associated with a transition from pelagic to benthic lifestyle, being the m... Read more »
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Premium RRBS Kit
Cellulophaga algicola alginate lyase and Pseudomonas aeruginosa Psl...
Published: February, 2025
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen that produces a biofilm containing the polysaccharides, alginate, Psl, and Pel, and caus... Read more »
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Megaruptor
Caloric restriction prevents inheritance of polycystic ovary syndro...
Published: February, 2025
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent metabolic and reproductive endocrine disorder with strong heritability. However, the independent ro... Read more »
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MagMeDIP kit
Epigenetic Regulation During Flatfish 2 Metamorphosis: Integrative ...
Published: February, 2025
Abstract: The regulation of gene expression plays a pivotal role in the complex metamorphic process of flatfishes, which oversees the dynamic alterations tha... Read more »
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Premium RRBS Kit

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