Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular c...
Published: December, 2025

Abstract: Chromatin regulators are frequently mutated or aberrantly expressed in hepatocellular carcinoma (HCC), suggesting that the dysregulation of chrom... Read more »

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Tagmentase
Refeeding with different levels of dietary carbohydrate modulates e...
Published: December, 2025

Abstract: The Nile tilapia (Oreochromis niloticus) exhibits a strong metabolic response to dietary carbohydrates (CHO). Short-term refeeding after fasting ... Read more »

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Antibody
Longevity-driven hepatic transcriptional programs mediate resilienc...
Published: November, 2025

Abstract: The liver plays a central role in regulating systemic metabolism, and its function declines with age, contributing to increased susceptibilit... Read more »
Targeted sequencing and iterative assembly of near-complete genomes
Published: November, 2025

Abstract: Complete telomere-to-telomere diploid genome assemblies have long posed significant challenges due to the intricate architecture of genomes. In dip... Read more »

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Megaruptor
Conserved heat shock factors HvHSFA2 and HvHSFA3 control barley hea...
Published: November, 2025

Abstract: Climate change requires optimizing stress responses in crops. Priming and memory of heat stress (HS) allow plants to improve their tolerance ag... Read more »

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Antibody
Antagonizing epigenetically controlled PAF/PAF-R pathway improves l...
Published: November, 2025

Abstract: Background and aims Platelet-activating factor (PAF) phospholipid is mainly produced by macrophages and involved in pro-inflammatory responses. We... Read more »
Refined ChIP‐Seq Protocol for High‐Quality Chromatin Profiling in S...
Published: November, 2025

Abstract: The chromatin immunoprecipitation followed by sequencing (ChIP‐seq) assay is an instrumental and accurate method for understanding chromatin dynami... Read more »
Human iPSCs-based modeling unveils SETBP1 as a driver of chromatin ...
Published: November, 2025

Abstract: Patients with GATA2 deficiency are predisposed to developing myelodysplastic neoplasms (MDS), which can progress to acute myeloid leukemia. Thi... Read more »

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Tagmentase
Tel1 is recruited at chromosomal loop/axis contact sites to modulat...
Published: November, 2025

Abstract: During meiosis, the programmed formation of DNA double-strand breaks (DSBs) by Spo11, a conserved topoisomerase VI family protein, initiates ho... Read more »

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IPure kit
Mucinous cystic neoplasms of the pancreas demonstrate in situ produ...
Published: November, 2025

Abstract: Introduction Mucinous cystic neoplasms (MCNs) are rare cystic tumors that may occur in the liver, pancreas, or retroperitoneum, defined histolog... Read more »
PRC1-mediated H2A.Zub promotes gene expression by preventing H3.1K2...
Published: November, 2025

Abstract: Background: PcG complexes are pivotal in orchestrating the transition from embryonic to vegetative development in plants. However, the mechani... Read more »

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Antibody
DNA methylation dynamics associated with visual system remodeling d...
Published: November, 2025

Abstract: Background: Flatfish metamorphosis involves dramatic tissue remodeling, including the migration of one eye to the opposite side of the body, e... Read more »

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Premium RRBS Kit
Epstein-Barr virus-transformed B-cells from a hypoxia model of the ...
Published: November, 2025

Abstract: Epstein-Barr virus (EBV) drives over 200,000 cancer cases annually, including diffuse large B-cell lymphoma, Burkitt lymphoma, and classic Hodg... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Sox8 is essential for vertebrate gastrulation
Published: November, 2025

Abstract: Gastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the precise orchestratio... Read more »

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Antibody
Stage-specific transcriptomic and DNA methylation responses to trip...
Published: November, 2025

Abstract: Background: Polyploidy, the condition of having more than two chromosome sets, is relatively common in plants but rare in animals, largely due... Read more »

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Premium RRBS Kit
PRKG1 hinders myogenic differentiation and predicts response to AKT...
Published: November, 2025

Abstract: Rhabdomyosarcoma (RMS) is marked by a myogenesis differentiation blockade, and while the AKT/mTOR pathway is universally activated, its pharmac... Read more »
Epigenomics of embryogenesis in turbot
Published: November, 2025

Abstract: Embryogenesis is the foundational step of ontogeny, where a complex organism emerges from a single totipotent cell. This process is orchestrate... Read more »

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Antibody ChIPmentation
Single-cell, multi-region profiling of the macaque brain across the...
Published: November, 2025

Abstract: Brain aging is a complex process with profound health and societal consequences. However, the molecular and cellular pathways that govern its tem... Read more »

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Tagmentase
The brain neurovascular epigenome and its association with dementia
Published: October, 2025

Abstract: Cerebral small vessel disease (SVD) is frequently comorbid with Alzheimer's disease (AD), and brain endothelial cells (BECs) express genes associ... Read more »

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Antibody Tagmentase
Disease-specific epigenetic deregulation of enhancers, transposons,...
Published: October, 2025

Abstract: Background: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), characterized by a fusion between the PML and RAR... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Upregulation of ALDH1 as an adaptive epigenetic response to anthrac...
Published: October, 2025

Abstract: Acute myeloid leukemia (AML) is a genetically heterogeneous malignancy characterized by the clonal proliferation of undifferentiated myeloid pr... Read more »

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Antibody Microplex Library Preparation kit
Retinoic acid and ascorbate synergize to suppress myeloid leukemia ...
Published: October, 2025

Abstract: Enhancing ten-eleven translocation 2 (TET2) activity through genetic or pharmacologic approaches, such as ascorbate supplementation, can slow mye... Read more »

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Antibody ATAC-seq
Effects of Maternal Peanut Intake and Breastfeeding Duration on Off...
Published: October, 2025

Abstract: Emerging evidence suggests that maternal diet during pregnancy and breastfeeding may influence epigenetic modifications in offspring genes related ... Read more »

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Infinium Human MethylationEPIC Array Service
Arginine Metabolism Supports De Novo Pyrimidine Biosynthesis to Blo...
Published: October, 2025

Abstract: Incompletely understood mechanisms serve to maintain Epstein-Barr virus (EBV) latency in most B-cell states, in which viral oncogene(s) are express... Read more »

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MagMeDIP kit
Seed structure and phosphorylation in the fuzzy coat impact tau see...
Published: October, 2025

Abstract: Tau misfolding into β-sheet–rich filaments and subsequent recruitment of monomeric tau are central to Alzheimer’s disease (AD) pat... Read more »
Tea-derived extracellular vesicles-mediated PDRN delivery activates...
Published: October, 2025

Abstract: The clinical translation of polydeoxyribonucleotide (PDRN), a bioactive agent with anti-inflammatory and tissue-repair properties, is hindered by s... Read more »

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Bioruptor Plus
Multigenerational temperature effects on paternal epigenetic inheri...
Published: October, 2025

Abstract: Environmental changes can induce epigenetic modifications, influencing gene expression, phenotype, and species adaptation. This study investigate... Read more »

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Premium RRBS Kit
PHF19 drives the formation of PRC2 clusters to enhance motility in ...
Published: October, 2025

Abstract: Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and di... Read more »

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Antibody Microplex Library Preparation kit
Global Mapping of Combinatorial Chromatin Regulatory Events Using H...
Published: October, 2025

Abstract: Epigenetic modulators, transcription factors, and chromatin-associated proteins collaboratively regulate essential genomic functions, such as tra... Read more »

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Tagmentase
OGFOD1 enables AML chemo- and nutrient stress resistance by regulat...
Published: October, 2025

Abstract: Acute myeloid leukemia (AML) commonly relapses after initial chemotherapy response. We assessed metabolic adaptations in chemoresistant cells in ... Read more »

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D-Plex small RNA-seq

 


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