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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Charting the regulatory landscape of TP53 on transposable elements ...
Published: May, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Cervicovaginal microbiome alters transcriptomic and epigenomic sign...
Published: May, 2025
Abstract: Background The cervicovaginal microbiome plays a critical role in women's health, with microbial communities dominated by Lactobacillus ... Read more »
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ATAC-seq
Epigenomic disorder and partial EMT impair luminal progenitor integ...
Published: April, 2025
Abstract: In breast cancer related to the BRCA1 mutation, luminal progenitor cells are believed to be the cells of origin, yet how these cells transform into... Read more »
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CUT&Tag
Drug-loaded indocyanine green J-aggregates activate metalloimmunoth...
Published: April, 2025
Abstract: Hepatocellular carcinoma (HCC) poses a significant therapeutic challenge, driving the need for novel treatment strategies. This study investigates ... Read more »
Epstein-Barr Virus-Driven B-Cell Transformation under Germinal Cent...
Published: April, 2025
Abstract: Epstein-Barr virus (EBV) contributes to over 200,000 cancers annually, predominantly aggressive lymphomas originating from hypoxic germinal centers... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
RNA G-quadruplex removal promotes a translational switch after meio...
Published: April, 2025
Abstract: Oocyte maturation-coupled mRNA post-transcriptional regulation is essential for the establishment of developmental potential. Previously, oocyte mR... Read more »
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D-Plex small RNA-seq
Unified molecular approach for spatial epigenome, transcriptome, an...
Published: April, 2025
Abstract: Spatial epigenomics and multiomics can provide fine-grained insights into cellular states but their widespread adoption is limited by the requireme... Read more »
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Tagmentase
The establishment of nuclear organization in mouse embryos is orche...
Published: April, 2025
Abstract: The folding of the genome in the 3D nuclear space is fundamental for regulating all DNA-related processes. The association of the genome with the... Read more »
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Antibody CUT&Tag
Recurrent spontaneous miscarriages from sperm after ABVD chemothera...
Published: April, 2025
Abstract: Lymphomas represent one of the most common malignant diseases in young men and an important issue is how treatments will affect their reproductive ... Read more »
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Premium RRBS Kit
An ISWI-related chromatin remodeller regulates stage-specific gene ...
Published: April, 2025
Abstract: ATP-dependent chromatin remodellers are specialized multiprotein machines that organize the genome in eukaryotic cells and regulate its accessibili... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors ATAC-seq
Complete sequencing of ape genomes
Published: April, 2025
Abstract: The most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our ... Read more »
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Megaruptor
Menin-MLL1 complex cooperates with NF-Y to promote HCC survival
Published: April, 2025
Abstract: Abstract Identification of new therapeutic targets in hepatocellular carcinoma (HCC) remains critical. Chromatin regulating complexes are frequent... Read more »
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Tagmentase
Embryo-scale single-cell chemical transcriptomics reveals dependenc...
Published: April, 2025
Abstract: Summary Organogenesis is a highly organized process that is conserved across vertebrates and is heavily dependent on intercellular signaling to ac... Read more »
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Tagmentase
Spatial transcriptomic imaging of an intact organism using volumetr...
Published: March, 2025
Abstract: Lymphatic, nervous and tumor tissues exhibit complex physiology arising from three-dimensional interactions within genetically unique microenvironm... Read more »
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Tagmentase
Repression of oxidative phosphorylation by NR2F2, MTERF3 and GDF15 ...
Published: March, 2025
Abstract: Lifestyle factors such as a Western diet or metabolic diseases like diabetes disrupt glucose homeostasis and induce stress responses, yet their imp... Read more »
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ATAC-seq
SIRT6 activator fucoidan extends healthspan and lifespan in aged wi...
Published: March, 2025
Abstract: Abstract SIRT6 is a protein deacylase, deacetylase, and mono-ADP-ribosylase (mADPr) regulating biological pathways important for longevity includi... Read more »
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Tagmentase
HSV-1 infection induces a downstream shift of the +1 nucleosome
Published: March, 2025
Abstract: Herpes simplex virus 1 (HSV-1) infection induces a loss of host transcriptional activity and widespread disruption of host transcription terminatio... Read more »
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Antibody
Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in reg...
Published: March, 2025
Abstract: The histone chaperone and transcription elongation factor SPT6 is integral to RNA polymerase II (RNAPII) activity. SPT6 also plays a crucial role i... Read more »
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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors
Human de novo mutation rates from a four-generation pedigree reference
Published: March, 2025
Abstract: Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five complementary short-read and long-read... Read more »
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Megaruptor
The Utah NeoSeq Project: a collaborative multidisciplinary program ...
Published: March, 2025
Abstract: Rapid genomic diagnostics in the Neonatal Intensive Care Unit represents a paradigm shift in medicine with increasing evidence of the utility of ea... Read more »
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DNA shearing
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ...
Published: March, 2025
Abstract: Microglial diversity arises from the interplay between inherent genetic programs and external environmental signals. However, the mechanisms by whi... Read more »
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iDeal ChIP-seq Kit for Histones
Spatially resolved genome-wide joint profiling of epigenome and tra...
Published: March, 2025
Abstract: The epigenome of a cell is tightly correlated with gene transcription, which controls cell identity and diverse biological activities. Recent advan... Read more »
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Tagmentase CUT&Tag
Cortico-striatal circuit mechanisms drive the effects of D1 dopamin...
Published: March, 2025
Abstract: Working memory capacity (WMC), the number of items remembered in a short-time interval, is regulated by fronto-striatal dopamine (DA) and is re... Read more »
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Bioruptor
Multi-step genomics on single cells and live cultures in sub-nanoli...
Published: March, 2025
Abstract: Abstract Single-cell genomics encompasses a set of methods whereby hundreds to millions of cells are individually subjected to multiplexed assays ... Read more »
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Tagmentase
Transcriptional stress induces the overexpression of novel lncRNAs ...
Published: March, 2025
Abstract: Long non-coding RNAs (lncRNAs) have been shown to play a role during transcriptional regulation in response to stress. However, their function unde... Read more »
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CRISPR
Activin A activation of Smad3 mitigates innate inflammation in mous...
Published: March, 2025
Abstract: Phosphorylation of Smad3 is a critical mediator of TGF-β signaling, which plays an important role in regulating innate immune responses. Howev... Read more »
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iDeal ChIP-qPCR
In vivo prime editing rescues photoreceptor degeneration in nonsens...
Published: March, 2025
Abstract: The next-generation gene editing tool, prime editing (PE), is adept at correcting point mutations precisely with high editing efficiency and rare o... Read more »
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Bioruptor
ZEB1 transcription factor induces tumor cell PD-L1 expression in me...
Published: March, 2025
Abstract: Tumor cells can evade antitumor immune response by expressing the PD-L1 ligand, leading to the inhibition of PD-1-expressing T lymphocytes. The mec... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
IER3: exploring its dual function as an oncogene and tumor suppressor
Published: March, 2025
Abstract: The IER3 gene has a complex role in cancer biology, acting either as a tumor suppressor or an oncogene, depending on the cancer type. This duality ... Read more »
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iDeal ChIP-seq Kit for Histones
Recurrent patterns of widespread neuronal genomic damage shared by ...
Published: March, 2025
Abstract: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer's disease (AD) are common neurodegenerative disorders for which t... Read more »
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Tagmentase

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