Publications,References

Extracellular vesicle-mediated trafficking of molecular cues during...
Published: October, 2024

Abstract: Cellular crosstalk is an essential process influenced by numerous factors, including secreted vesicles that transfer nucleic acids, lipids, and pro... Read more »

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Microplex Library Preparation kit

Pesticide-induced transgenerational alterations of genome-wide DNA ...
Published: October, 2024

Abstract: The unsustainable use of manmade chemicals poses significant threats to biodiversity and human health. Emerging evidence highlights the potential o... Read more »

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Premium RRBS Kit

5-Hydroxymethylcytosine in circulating cell-free DNA as a potential...
Published: October, 2024

Abstract: Background SLE is a complex autoimmune disease with heterogeneous manifestations and unpredictable outcomes. Early diagnosis is challenging ... Read more »

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Antibody

RNA m5C oxidation by TET2 regulates chromatin state and leukaemogen...
Published: October, 2024

Abstract: Mutation of tet methylcytosine dioxygenase 2 (encoded by TET2) drives myeloid malignancy initiation and progression1,2,3. TET2 deficiency is k... Read more »

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Antibody

RNA polymerase II transcription initiation in holo-TFIID-depleted m...
Published: September, 2024

Abstract: The recognition of core promoter sequences by TFIID is the first step in RNA polymerase II (Pol II) transcription initiation. Metazoan holo-TFIID i... Read more »

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Microplex Library Preparation kit

Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling
Published: September, 2024

Abstract: Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals,... Read more »

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Antibody

Legionella pneumophila modulates macrophage functions through epige...
Published: September, 2024

Abstract: Legionella pneumophila is a pathogen which can lead to a severe form of pneumonia in humans known as Legionnaires disease after replication in... Read more »

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Antibody

Two-factor authentication underpins the precision of the piRNA pathway
Published: September, 2024

Abstract: The PIWI-interacting RNA (piRNA) pathway guides the DNA methylation of young, active transposons during germline development in male mice. piRNAs t... Read more »

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CUT&Tag

Single-cell multi-omics, spatial transcriptomics and systematic per...
Published: September, 2024

Abstract: Cranial neural crest (NC) cells, which can migrate, adopt multiple fates, and form most of the craniofacial skeleton, are an excellent model for st... Read more »

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Antibody True MicroChIP kit

Optimization of ribosome profiling in plants including structural a...
Published: September, 2024

Abstract: Background Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Acr... Read more »

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D-Plex small RNA-seq

Systematic prioritization of functional variants and effector genes...
Published: September, 2024

Abstract: Genome-wide association studies of colorectal cancer (CRC) have identified 170 autosomal risk loci. However, for most of these, the functional vari... Read more »

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Antibody

An ERRα-ZEB1 transcriptional signature predicts survival in triple-...
Published: September, 2024

Abstract: Background. Transcription factors (TFs) act together with co-regulators to modulate the expression of their target genes, which eventually dictate... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Auto-expansion of in vivo HDAd-transduced hematopoietic stem cells ...
Published: September, 2024

Abstract: We developed an in vivo hematopoietic stem cell (HSC) gene therapy approach that does not require cell transplantation. To achieve t... Read more »

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Tagmentase

Nuclear lamin A/C phosphorylation by loss of androgen receptor lead...
Published: September, 2024

Abstract: Alterations in nuclear structure and function are hallmarks of cancer cells. Little is known about these changes in Cancer-Associated Fibroblasts (... Read more »

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iDeal ChIP-seq Kit for Transcription Factors Tagmentase

A critical role for HNF4α in polymicrobial sepsis-associated metabo...
Published: September, 2024

Abstract: In sepsis, limited food intake and increased energy expenditure induce a starvation response, which is compromised by a quick decline in the expres... Read more »

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Tagmentase

Bivalent chromatin accommodates survivin and BRG1/SWI complex to ac...
Published: September, 2024

Abstract: Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3)... Read more »

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Antibody

Triphenyl Phosphate Alters Methyltransferase Expression and Induces...
Published: August, 2024

Abstract: Emerging environmental contaminants, organophosphate flame retardants (OPFRs), pose significant threats to ecosystems and human health. Despite num... Read more »

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Premium RRBS Kit

An atlas of the human liver diurnal transcriptome and its perturbat...
Published: August, 2024

Abstract: Chronic liver disease and cancer are global health challenges. The role of the circadian clock as a regulator of liver physiology and disease is we... Read more »

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Microplex Library Preparation kit

A PRE loop at the dac locus acts as a topological chromatin structu...
Published: August, 2024

Abstract: Three-dimensional (3D) genome folding has a fundamental role in the regulation of developmental genes by facilitating or constraining chromatin int... Read more »

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ChIP-qPCR

Temporal and spatial niche partitioning in a retrotransposon commun...
Published: August, 2024

Abstract: Transposable elements (TEs), widespread genetic parasites, pose potential threats to the stability of their host genomes. Hence, the interactions o... Read more »

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ATAC-seq

Inherited defects of piRNA biogenesis cause transposon de-repressio...
Published: August, 2024

Abstract: piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dy... Read more »

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D-Plex small RNA-seq

Detection of genome structural variation in normal cells and tissue...
Published: August, 2024

Abstract: Detecting somatic mutations in normal cells and tissues is notoriously challenging due to their low abundance, orders of magnitude below the sequen... Read more »

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Tagmentase

Association between TNF-α, cortisol levels, and exposure to PM10 an...
Published: August, 2024

Abstract: Purpose The most harmful atmospheric pollutant for human health is particulate matter (PM). We analyzed the correlation between short-term lag exp... Read more »

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MagMeDIP kit

Human induced pluripotent stem cells for live cell cycle monitoring...
Published: August, 2024

Abstract: The fluorescence ubiquitination cell cycle inhibitor (FUCCI) has been introduced to monitor cell cycle activity in living cells, including human in... Read more »

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Antibody CRISPR

LL37/self-DNA complexes mediate monocyte reprogramming
Published: August, 2024

Abstract: LL37 alone and in complex with self-DNA triggers inflammatory responses in myeloid cells and plays a crucial role in the development of systemic au... Read more »

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Antibody

Innate immune training restores pro-reparative myeloid functions to...
Published: July, 2024

Abstract: The reduced ability of the central nervous system to regenerate with increasing age limits functional recovery following demyelinating injury. Prev... Read more »

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Antibody iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services

Biochemical role of FOXM1-dependent histone linker H1B in human epi...
Published: July, 2024

Abstract: Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and different... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

A multiomic atlas of the aging hippocampus reveals molecular change...
Published: July, 2024

Abstract: Aging involves the deterioration of organismal function, leading to the emergence of multiple pathologies. Environmental stimuli, including lifesty... Read more »

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Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones

Loss of tumor suppressors promotes inflammatory tumor microenvironm...
Published: July, 2024

Abstract: Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we repo... Read more »

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Antibody CRISPR

Epigenetic alterations affecting hematopoietic regulatory networks ...
Published: July, 2024

Abstract: Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile t... Read more »

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Antibody Microplex Library Preparation kit

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