Publications,References

Cis-regulatory interfaces reveal the molecular mechanisms underlyin...
Published: April, 2024

Abstract: Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulator... Read more »

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CRISPR

Systematic mapping of TF-mediated cell fate changes by a pooled ind...
Published: April, 2024

Abstract: Transcriptional regulation controls cellular functions through interactions between transcription factors (TFs) and their chromosomal targets. Howe... Read more »

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ATAC-seq

Differential DNA methylation in iPSC-derived dopaminergic neurons: ...
Published: April, 2024

Abstract: Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) feat... Read more »

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Premium RRBS Kit

Epigenetics and suicide: investigating altered H3K14ac unveiled dif...
Published: March, 2024

Abstract: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to ch... Read more »

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ChIPmentation

TET2 Deficiency Increases the Competitive Advantage of Hematopoieti...
Published: March, 2024

Abstract: Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, th... Read more »

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Chromatin Shearing

Integrative network analysis of differentially methylated regions t...
Published: March, 2024

Abstract: Integrative network analysis (INA) is important for identifying gene modules or epigenetically regulated molecular pathways in diseases. This study... Read more »

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Infinium Human MethylationEPIC Array Service

High-throughput sequencing of insect specimens with sub-optimal DNA...
Published: March, 2024

Abstract: Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may ... Read more »

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Tagmentase

Technical considerations for cost-effective transposon directed ins...
Published: March, 2024

Abstract: Transposon directed insertion-site sequencing (TraDIS), a variant of transposon insertion sequencing commonly known as Tn-Seq, is a high-throughput... Read more »

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Tagmentase

Protocol to isolate nuclei from Chlamydomonas reinhardtii for ATAC ...
Published: March, 2024

Abstract: Highlights Optimized isolation of nuclei from the green model alga Chlamydomonas reinhardtii Tag-free isolation from both cell-w... Read more »

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ATAC-seq

Chromatin profiling reveals TFAP4 as a critical transcriptional reg...
Published: March, 2024

Abstract: Background Satellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintena... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

On the identification of differentially-active transcription factor...
Published: March, 2024

Abstract: ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenome... Read more »

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Tagmentase

SURVIVIN IN SYNERGY WITH BAF/SWI COMPLEX BINDS BIVALENT CHROMATIN R...
Published: March, 2024

Abstract: This study explores a regulatory role of oncoprotein survivin on the bivalent regions of chromatin (BvCR) characterized by concomitant deposition o... Read more »

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Antibody

Focal cortical dysplasia type II-dependent maladaptive myelination ...
Published: March, 2024

Abstract: Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified in... Read more »

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IPure kit iDeal ChIP-seq Kit for Transcription Factors

Pervasive translation of Xrn1-sensitive unstable long non-coding RN...
Published: March, 2024

Abstract: Despite being predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes. However, the landscape and bi... Read more »

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D-Plex small RNA-seq

A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at ...
Published: March, 2024

Abstract: Purpose: DNA methylation alterations are widespread in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), some of which appear to hav... Read more »

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MagMeDIP kit

Making Biological Ageing Clocks Personal
Published: February, 2024

Abstract: Background Age is the most important risk factor for the majority of human diseases. Addressing the impact of age-related diseases has becom... Read more »

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Infinium Human MethylationEPIC Array Service

Interplay between coding and non-coding regulation drives the Arabi...
Published: February, 2024

Abstract: Translation of seed stored mRNAs is essential to trigger germination. However, when RNAPII re-engages RNA synthesis during the seed-to-seedling tra... Read more »

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ATAC-seq

Cellular reprogramming in vivo initiated by SOX4 pioneer factor act...
Published: February, 2024

Abstract: Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is ... Read more »

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Tagmentase

MYB/LINC00092 regulatory axis promotes the progression of papillary...
Published: February, 2024

Abstract: Introduction:Thyroid carcinoma is the most frequent malignancy in different endocrine-related tumours. In this study, we demonstrated a long non-co... Read more »

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iDeal ChIP-qPCR

Plasticity-induced repression of Irf6 underlies acquired resistance...
Published: February, 2024

Abstract: Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic d... Read more »

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Tagmentase

Multiomics uncovers the epigenomic and transcriptomic response to v...
Published: February, 2024

Abstract: Uncovering the epigenomic regulation of immune responses is essential for a comprehensive understanding of host defence mechanisms but remains poor... Read more »

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Microplex Library Preparation kit ChIPmentation

Neurofibromin 1 controls metabolic balance and Notch-dependent quie...
Published: February, 2024

Abstract: Patients affected by neurofibromatosis type 1 (NF1) frequently show muscle weakness with unknown etiology. Here we show that, in mice, Neurofibromi... Read more »

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MagMeDIP kit

Inhibition of Aurora kinase induces endogenous retroelements to ind...
Published: February, 2024

Abstract: Type I interferon signaling is a crucial component of anti-viral immunity that has been linked to promoting the efficacy of some chemotherapeutic d... Read more »

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Infinium Human MethylationEPIC Array Service

The transcriptional regulatory network modulating human trophoblast...
Published: February, 2024

Abstract: During human pregnancy, extravillous trophoblasts play crucial roles in placental invasion into the maternal decidua and spiral artery remodeling. ... Read more »

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ATAC-seq

Cancer Cell Biomechanical Properties Accompany Tspan8-Dependent Cut...
Published: February, 2024

Abstract: The intrinsic biomechanical properties of cancer cells remain poorly understood. To decipher whether cell stiffness modulation could increase m... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibrob...
Published: February, 2024

Abstract: There are significant commonalities among several pathologies involving fibroblasts, ranging from auto-immune diseases to fibrosis and cancer. Earl... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Long-term effects of myo-inositol on traumatic brain injury: Epigen...
Published: January, 2024

Abstract: Background and purpose Traumatic brain injury (TBI) and its consequences remain great challenges for neurology. Consequences of TBI are associated... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Aseptic loosening around total joint replacement in humans is regul...
Published: January, 2024

Abstract: Background: Total joint replacement for osteoarthritis is one of the most successful surgical procedures in modern medicine. However, aseptic ... Read more »

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D-Plex small RNA-seq

CompDuplex: Accurate detection of somatic mutations by duplex-seq w...
Published: January, 2024

Abstract: Somatic mutations continuously accumulate in the human genome, posing vulnerabilities towards aging and increased risk of vario... Read more »

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Tagmentase

Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor...
Published: January, 2024

Abstract: The POU2F3-POU2AF2/3 (OCA-T1/2) transcription factor complex is the master regulator of the tuft cell lineage and tuft cell-like small cell lung ca... Read more »

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Bioruptor iDeal ChIP-seq Kit for Transcription Factors

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