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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

De novo assembly and delivery of synthetic megabase-scale human DNA...
Published: August, 2025
Abstract: Epigenetic modifications on natural chromosomes are inherited and maintained in a default state, making it challenging to remove intrinsic mark... Read more »
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Antibody
Lysine-specific demethylase 1 regulates hematopoietic stem cell exp...
Published: August, 2025
Abstract: The lysine-specific demethylase 1 (LSD1) regulates hematopoietic stem cell differentiation and has been identified as a therapeutic target in h... Read more »
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Antibody
Active chromatin marks and up-regulation of FOXC1 in uterine epithe...
Published: August, 2025
Abstract: Advanced maternal age increases the risk of pregnancy complications due, in part, to changes in the uterine environment. Here, we show that uteri... Read more »
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Antibody Microplex Library Preparation kit
H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endo...
Published: August, 2025
Abstract: Endometriosis is a common gynecological condition associated with chronic inflammation, epigenetic dysregulation, and infertility. The TET1 gene,... Read more »
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Antibody
DNA methylation at retrotransposons protects the germline by preven...
Published: August, 2025
Abstract: Silencing evolutionary young retrotransposons by cytosine DNA methylation is essential for spermatogenesis, as failure to methylate their promote... Read more »
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CUT&Tag
Evidence of neuronal DNA damage in the brains of patients with Rett...
Published: August, 2025
Abstract: Rett syndrome is characterized by the postnatal loss of neurophysiological function and regression of childhood development. Because the syndrome... Read more »
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Antibody
TransTag enables simple and efficient transgene mapping in zebrafis...
Published: July, 2025
Abstract: Zebrafish has become a preeminent model for developmental biology research, largely due to the ease of transgenesis. Despite widespread usage of tr... Read more »
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Tagmentase
SUMO operates from a unique long tandem repeat to keep innate immun...
Published: July, 2025
Abstract: The SUMO pathway mainly functions to repress innate immunity in myeloid cells. Inactivating sumoylation triggers a strong, noncanonical, type I... Read more »
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Antibody Microplex Library Preparation kit
Genetic disruption of the baculum compromises the ability of male m...
Published: July, 2025
Abstract: The baculum, a bone in the penis of many mammal species, shows an astonishing level of morphological divergence between species. Despite hundre... Read more »
High-resolution map of the Plasmodium falciparum genome reveals MOR...
Published: July, 2025
Abstract: Genome organization plays an important role in silencing compacted, heterochromatinized genes in the most virulent human malaria parasite, Plas... Read more »
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Microplex Library Preparation kit ChIP Cross-link Gold
Somatic mutations in TBX3 promote hepatic clonal expansion by accel...
Published: July, 2025
Abstract: Somatic mutations that increase clone fitness or resist disease are positively selected, but the impact of these mutations on organismal health r... Read more »
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Antibody
Traditional Chinese Medicine Luo Tong Formula attenuates retinal in...
Published: July, 2025
Abstract: Background: Diabetic retinopathy (DR) is a leading cause of blindness in the adult population. Luo-Tong Formula (LTF), a traditional Chinese medici... Read more »
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Antibody
Liebenberg syndrome severity arises from variations in Pitx1 locus ...
Published: July, 2025
Abstract: Enhancer hijacking, a common cause of gene misregulation linked to disease, occurs when non-matching enhancers and promoters interact ectopical... Read more »
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Antibody
Dissecting the epigenetic regulation of the fetal hemoglobin genes ...
Published: July, 2025
Abstract: Beta-hemoglobinopathies are severe genetic diseases caused by mutations affecting the production of the adult β-globin chain. The clinical... Read more »
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Antibody
TP53 missense-specific transcriptional plasticity drives resistance...
Published: July, 2025
Abstract: In ~70% of patients with pancreatic ductal adenocarcinoma, the TP53 gene acquires gain-of-function (GOF) mutations leading to rapid dis... Read more »
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Microplex Library Preparation kit
Spatial profiling of chromatin accessibility in formalin-fixed para...
Published: July, 2025
Abstract: Formalin-fixed paraffin-embedded (FFPE) samples represent a vast, untapped resource for epigenomic research, yet molecular tools for deep analysi... Read more »
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Tagmentase
Constitutive expression of the transcriptional co-activator IκBζ pr...
Published: June, 2025
Abstract: IκBζ, a rather unknown co-regulator of NF-κB, can either activate or repress a subset of NF-κB target genes. While its r... Read more »
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Antibody
Quantitative measurement of phenotype dynamics during cancer drug r...
Published: June, 2025
Abstract: Cancer treatment frequently fails due to the evolution of drug-resistant cell phenotypes driven by genetic or non-genetic changes. The origin... Read more »
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Tagmentase
Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells
Published: June, 2025
Abstract: Iron is an irreplaceable co-factor for metabolism. Iron deficiency affects >1 billion people and decreased iron availability impairs immunit... Read more »
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Antibody
Extrusion fountains are restricted by WAPL-dependent cohesin releas...
Published: June, 2025
Abstract: Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-eff... Read more »
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Antibody
RSK1-driven TRIM28/E2F1 feedback loop promotes castration-resistant...
Published: June, 2025
Abstract: Castration-resistant prostate cancer (CRPC) marks the advanced and lethal stage of prostate cancer (PCa). TRIM28, also known as KAP1, is a transc... Read more »
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Tagmentase
Polycomb Repressive Complex 2 facilitates the transition from heter...
Published: June, 2025
Abstract: The seed-to-seedling transition represents a key developmental and metabolic switch in plants. Catabolism of seed storage reserves fuels germinat... Read more »
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IPure kit
CRAMP1 drives linker histone expression to enable Polycomb repression
Published: June, 2025
Abstract: In contrast to the well-understood role of core histones in DNA packaging, the function of the linker histone (H1) remains enigmatic. Challenging... Read more »
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ATAC-seq
Impact of polyethylene terephthalate nanoplastics (PET) on fibrobla...
Published: June, 2025
Abstract: Plastic pollution has become a major environmental and public health issue due to rising global production. Nanoplastics (NPs) are especially con... Read more »
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Bioruptor
A spatially organized Cd24a+/ Pax9+ stem cell core governs postnata...
Published: June, 2025
Abstract: Mineralized tissues are fundamental in mechanical support and protection in vertebrates. Their formation by progenitor cells during development... Read more »
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Antibody
Temporal and spatial niche partitioning in a retrotransposon commun...
Published: June, 2025
Abstract: Transposable elements (TEs) are genetic parasites that can potentially threaten the stability of the genomes they colonize. Nonetheless, TEs pe... Read more »
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ATAC-seq
The impact of Fulvestrant on Estrogen Receptor-Driven Chromatin Dyn...
Published: June, 2025
Abstract: Epigenetic dysregulations are linked to various diseases, including cancer. Among them, breast cancer is the second leading cause of cancer-related... Read more »
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CUT&Tag
Coupling Immunoprecipitation with Multiplexed Digital PCR for Cell-...
Published: June, 2025
Abstract: Colorectal cancer (CRC) remains a major global health challenge, with an increasing incidence of early-onset cases among young adults. Targeted... Read more »
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MagMeDIP kit IPure kit
Androgen receptor-mediated assisted loading of the glucocorticoid r...
Published: June, 2025
Abstract: Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biological processes, with significant implication... Read more »
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Tagmentase
Charting the regulatory landscape of TP53 on transposable elements ...
Published: June, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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iDeal ChIP-seq Kit for Transcription Factors

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