Publications,References

Mutant FUS induces chromatin reorganization in the hippocampus anda...
Published: June, 2023

Abstract: Cytoplasmic mislocalization of the nuclear Fused in Sarcoma (FUS) protein is associated to amyotrophic lateral sclerosis (ALS) and frontotemporal d... Read more »

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Antibody Microplex Library Preparation kit ChIP Cross-link Gold

Effect of Aerobic/Strength Training on RANKL Gene DNA Methylation L...
Published: June, 2023

Abstract: BACKGROUND: The osteoclastogenesis RANKL gene plays a key role in bone remodeling. The hypomethylation of its promoter region may cause osteoporosi... Read more »

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Newly added

Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin conden...
Published: May, 2023

Abstract: The compaction of chromatin is a prevalent paradigm in gene repression. Chromatin compaction is commonly thought to repress transcription by restri... Read more »

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ATAC-seq

Pathologic HDAC1/c-Myc signaling axis is responsible forangiotensin...
Published: May, 2023

Abstract: High-fat diet (HFD)-induced obesity is a cause of resistant hypertension. We have shown a possible link between histone deacetylases (HDACs) and re... Read more »

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Antibody

Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADPribosylation d...
Published: May, 2023

Abstract: In light of the numerous studies identifying post-transcriptional regulators on the surface of the endoplasmic reticulum (ER), we asked whether the... Read more »

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D-Plex RNA-seq kit D-Plex small RNA-seq

The circadian clock CRY1 regulates pluripotent stem cell identity a...
Published: May, 2023

Abstract: Distinct metabolic conditions rewire circadian-clock-controlled signaling pathways leading to the de novo construction of signal transduction netwo... Read more »

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Antibody

Neonatal immune challenge poses a sex-specific risk for epigeneticm...
Published: May, 2023

Abstract: While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing eviden... Read more »

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iDeal ChIP-seq Kit for Histones

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade tosuppress ...
Published: May, 2023

Abstract: Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However,... Read more »

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iDeal ChIP-qPCR

Knockout of TRDMT1 methyltransferase affects DNA methylome ingliobl...
Published: May, 2023

Abstract: Purpose: We have previously shown that TRDMT1 methyltransferase is a regulator of chemotherapy-associated responses in glioblastoma cells. Des... Read more »

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Premium RRBS Kit

UMSBP2 is chromatin remodeler that functions in regulation of genee...
Published: May, 2023

Abstract: Universal Minicircle Sequence binding proteins (UMSBPs) are CCHC-type zinc-finger proteins that bind the single-stranded G-rich UMS sequence, conse... Read more »

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ATAC-seq

SOX expression in prostate cancer drives resistance to nuclear horm...
Published: May, 2023

Abstract: The development of androgen receptor signaling inhibitor (ARSI) drug resistance in prostate cancer (PC) remains therapeutically challenging. Our gr... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Low-nutrient diet in larvae stage causes enhancement in dopaminemo...
Published: May, 2023

Abstract: Nutrient scarcity is a frequent adverse condition that organisms face during their development. This condition may lead to long-lasting effects on ... Read more »

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D-Plex mRNA-seq kit

Nickel and Cobalt Induced Toxicity in Paramecium: TheCellular View ...
Published: May, 2023

Abstract: Cobalt and Nickel show increasing pollution in our environment. We analyzed their combined toxicity and uptake mechanisms in the early food chain b... Read more »

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D-Plex mRNA-seq kit

Towards a human brain EV atlas: Characteristics of EVs from differe...
Published: May, 2023

Abstract: Extracellular vesicles (EVs) are released from different cell types in the central nervous system (CNS) and play roles in regulating physiological ... Read more »

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D-Plex small RNA-seq

Reversible transitions between noradrenergic and mesenchymal tumori...
Published: May, 2023

Abstract: Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regu... Read more »

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iDeal ChIP-seq Kit for Histones

The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cellfate.
Published: May, 2023

Abstract: Placental development relies on coordinated cell fate decisions governed by signalling inputs. However, little is known about how signalling cues a... Read more »

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Antibody

Epigenetic silencing of selected hypothalamic neuropeptides in narc...
Published: May, 2023

Abstract: Narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic neuropeptide hypocretin/orexin (HCRT), unanimously beli... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

RUNX1 colludes with NOTCH1 to reprogram chromatin in T-cell acutely...
Published: May, 2023

Abstract: Runt-related transcription factor 1 (RUNX1) is oncogenic in diverse types of leukemia and epithelial cancers where its expression is associated wit... Read more »

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Antibody

Landscape of prostate-specific membrane antigen heterogeneity andre...
Published: April, 2023

Abstract: Tumor expression of prostate-specific membrane antigen (PSMA) is lost in 15-20\% of men with castration-resistant prostate cancer (CRPC), yet the u... Read more »

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Antibody

Epigenetic modifier alpha-ketoglutarate modulates aberrant gene bod...
Published: April, 2023

Abstract: BACKGROUND: Diabetic cardiomyopathy (DCM) is a leading cause of death in diabetic patients. Hyperglycemic myocardial microenvironment significantly... Read more »

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MagMeDIP kit Antibody hMeDIP

Comprehensive epigenomic profiling reveals the extent of disease-sp...
Published: April, 2023

Abstract: Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis characterized by enthesitis of the spine and sacroiliac joints. Ge... Read more »

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Antibody

Spatial epigenome-transcriptome co-profiling of mammalian tissues.
Published: April, 2023

Abstract: Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular sta... Read more »

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Tagmentase CUT&Tag

Transient suppression of SUMOylation in embryonic stem cells genera...
Published: April, 2023

Abstract: Recent advances in synthetic embryology have opened new avenues for understanding the complex events controlling mammalian peri-implantation develo... Read more »

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Microplex Library Preparation kit

A kinesin-based approach for inducing chromosome-specific mis-segre...
Published: April, 2023

Abstract: Various cancer types exhibit characteristic and recurrent aneuploidy patterns. The origins of these cancer type-specific karyotypes are still unkno... Read more »

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Antibody CRISPR

Farrerol directly activates the deubiqutinase UCHL3 to promote DNAr...
Published: April, 2023

Abstract: Farrerol, a natural flavanone, promotes homologous recombination (HR) repair to improve genome-editing efficiency, but the specific protein that fa... Read more »

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Antibody

Sperm DNA methylation is predominantly stable in mice offspring bor...
Published: April, 2023

Abstract: BACKGROUND: Spermatogonial stem cell transplantation (SSCT) is proposed as a fertility therapy for childhood cancer survivors. SSCT starts with cry... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

The Effect of Metformin and Carbohydrate-Controlled Diet onDNA Meth...
Published: April, 2023

Abstract: Polycystic ovary syndrome (PCOS) is an endocrine disease associated with infertility and metabolic disorders in reproductive-aged women. In this st... Read more »

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Bioruptor Antibody

RNA landscapes of brain tissue and brain tissue-derived extracellul...
Published: April, 2023

Abstract: Antiretroviral treatment regimens can effectively control HIV replication and some aspects of disease progression. However, molecular events in end... Read more »

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D-Plex small RNA-seq

Distinct regulation of EZH2 and its repressive H3K27me3 mark inPoly...
Published: April, 2023

Abstract: Merkel cell carcinoma (MCC) is an aggressive skin cancer for which Merkel cell polyomavirus (MCPyV) integration and expression of viral oncogenes s... Read more »

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Antibody

YAP/BRD4-controlled ROR1 promotes tumor-initiating cells andhyperpr...
Published: April, 2023

Abstract: Tumor-initiating cells are major drivers of chemoresistance and attractive targets for cancer therapy, however, their identity in human pancreatic ... Read more »

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Tagmentase

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