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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

p300 suppresses the transition of myelodysplastic syndromes to acut...
Published: October, 2021

Abstract: Myelodysplastic syndromes (MDS) are hematopoietic stem and progenitor cell (HSPC) malignancies characterized by ineffective hematopoiesis and an in... Read more »

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Antibody
Tracing the emergence of primordial germ cells from bilaminar disc ...
Published: October, 2021

Abstract: Rabbit embryos develop as bilaminar discs at gastrulation as in humans and most other mammals, whereas rodents develop as egg cylinders. Primordial... Read more »

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Antibody
NR4A1 regulates expression of immediate early genes, suppressingrep...
Published: October, 2021

Abstract: Deregulation of oncogenic signals in cancer triggers replication stress. Immediate early genes (IEGs) are rapidly and transiently expressed followi... Read more »

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Antibody
Establishment of a second generation homozygous CRISPRa human induc...
Published: October, 2021

Abstract: CRISPR/Cas9 technology based on nuclease inactive dCas9 and fused to the heterotrimeric VPR transcriptional activator is a powerful tool to enhance... Read more »

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CRISPR
Regulatory interplay between Vav1, Syk and β-catenin occurs in lung...
Published: October, 2021

Abstract: Vav1 exhibits two signal transducing properties as an adaptor protein and a regulator of cytoskeleton organization through its Guanine nucleotide E... Read more »

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Antibody iDeal ChIP-qPCR ChIP Cross-link Gold
MICAL1 regulates actin cytoskeleton organization, directional cellm...
Published: October, 2021

Abstract: The Molecule Interacting with CasL 1 (MICAL1) monooxygenase has emerged as an important regulator of cytoskeleton organization via actin oxidation.... Read more »

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Antibody CRISPR
Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Ne...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service) DNA Methylation
Epigenetic control of region-specific transcriptional programs in m...
Published: September, 2021

Abstract: Astrocytes from the cerebral cortex (CTX) and cerebellum (CB) share basic molecular programs, but also form distinct spatial and functional subtype... Read more »

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Antibody
Differential contribution to gene expression prediction of histonem...
Published: September, 2021

Abstract: The ChIP-seq signal of histone modifications at promoters is a good predictor of gene expression in different cellular contexts, but whether this i... Read more »

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Antibody
SUV39 SET domains mediate crosstalk of heterochromatic histone marks.
Published: September, 2021

Abstract: The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heteroch... Read more »

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Bioruptor Antibody
Chromosomal variations of species revealed by FISH with rDNAs andc...
Published: September, 2021

Abstract: Lycoris species have various chromosome numbers and karyotypes, but all have a constant total number of chromosome major arms. In addition to three... Read more »

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Universal Plant ChIP-seq Kit
Coordination of EZH2 and SOX2 specifies human neural fate decision.
Published: September, 2021

Abstract: Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the... Read more »

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Antibody
PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs,a...
Published: September, 2021

Abstract: Long-read sequencing has been shown to have advantages in structural variation (SV) detection and methylation calling. Many studies focus either on... Read more »

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Megaruptor
Alveolar macrophages from persons living with HIV show impairedepig...
Published: September, 2021

Abstract: Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of recent infection with Mycobacte... Read more »

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Microplex Library Preparation kit
Establishing community reference samples, data and call sets forben...
Published: September, 2021

Abstract: The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algo... Read more »

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Megaruptor
Transcriptome and Methylome Analysis Reveal ComplexCross-Talks betw...
Published: September, 2021

Abstract: BACKGROUND: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two hormones. Here we ch... Read more »

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MethylCap kit
Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells.
Published: September, 2021

Abstract: Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a... Read more »

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Antibody
LeafGo: Leaf to Genome, a quick workflow to produce high-quality de...
Published: September, 2021

Abstract: Currently, different sequencing platforms are used to generate plant genomes and no workflow has been properly developed to optimize time, cost, an... Read more »

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Megaruptor
The prolyl-isomerase PIN1 is essential for nuclear Lamin-Bstructure...
Published: September, 2021

Abstract: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposab... Read more »

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Antibody
DOT1L O-GlcNAcylation promotes its protein stability andMLL-fusion ...
Published: September, 2021

Abstract: Histone lysine methylation functions at the interface of the extracellular environment and intracellular gene expression. DOT1L is a versatile hist... Read more »

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Antibody
WT1 regulates HOXB9 gene expression in a bidirectional way.
Published: September, 2021

Abstract: The homeoboxB9 (HOXB9) gene is necessary for specification of the anterior-posterior body axis during embryonic development and expressed in variou... Read more »

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Antibody
INTS11 regulates hematopoiesis by promoting PRC2 function.
Published: September, 2021

Abstract: INTS11, the catalytic subunit of the Integrator (INT) complex, is crucial for the biogenesis of small nuclear RNAs and enhancer RNAs. However, the ... Read more »

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Antibody Microplex Library Preparation kit
Histone deacetylase 4 deletion broadly affects cardiac epigeneticre...
Published: September, 2021

Abstract: Histone deacetylase 4 (HDAC4) is a member of class IIa histone deacetylases (class IIa HDACs) and is believed to possess a low intrinsic deacetylas... Read more »

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IP-Star Antibody
Genome-wide epigenomic analyses in patients with nociceptive andneu...
Published: September, 2021

Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »

Tags
Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
The related coactivator complexes SAGA and ATAC control embryonicst...
Published: September, 2021

Abstract: SUMMARY SAGA (Spt-Ada-Gcn5 acetyltransferase) and ATAC (Ada-two-A-containing) are two related coactivator complexes, sharing the same histone acety... Read more »

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Microplex Library Preparation kit
De novo genome assembly of the marine teleost, bluefin trevally (Ca...
Published: September, 2021

Abstract: The bluefin trevally, Caranx melampygus, also known as the bluefin kingfish or bluefin jack, is known for its remarkable, bright-blue fins. This ma... Read more »

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Megaruptor
Genome-wide and sister chromatid-resolved profiling of protein occu...
Published: September, 2021

Abstract: Elucidating the mechanisms underlying chromatin maintenance upon genome replication is critical for the understanding of how gene expression progra... Read more »

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Antibody
Epigenetic remodelling of enhancers in response to estrogen depriva...
Published: September, 2021

Abstract: Estrogen hormones are implicated in a majority of breast cancers and estrogen receptor alpha (ER), the main nuclear factor mediating estrogen signa... Read more »

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Antibody iDeal ChIP-seq Kit for Histones iDeal ChIP-qPCR hMeDIP
Functional microRNA targetome undergoes degeneration-induced shift ...
Published: August, 2021

Abstract: Background: MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular... Read more »

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D-Plex small RNA-seq
Biobehavioral organization shapes the immune epigenome in infant rh...
Published: August, 2021

Abstract: How individuals respond to and cope with stress is linked with their health and well-being. It is presumed that early stress responsiveness helps s... Read more »

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Premium RRBS Kit

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