Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Effects of GSK-J4 on JMJD3 Histone Demethylase in Mouse Prostate Ca...
Published: May, 2022

Abstract: Background/aim: Histone methylation status is required to control gene expression. H3K27me3 is an epigenetic tri-methylation modification to h... Read more »

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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
Epigenetic Mechanisms Mediating Cell State Transitions in Chondrocytes
Published: May, 2022

Abstract: Epigenetic modifications play critical roles in regulating cell lineage differentiation, but the epigenetic mechanisms guiding specific differentia... Read more »

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Bioruptor Antibody Microplex Library Preparation kit True MicroChIP kit
Global DNA methylation and cellular 5-methylcytosine and H4 acetyla...
Published: May, 2022

Abstract: Despite the importance of dormancy and dormancy cycling for plants' fitness and life cycle phenology, a comprehensive characterization of the globa... Read more »
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesi...
Published: April, 2022

Abstract: People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and major depressive disorder (... Read more »

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D-Plex small RNA-seq
AUXIN RESPONSE FACTOR 16 (StARF16) regulates defense gene StNPR1 up...
Published: April, 2022

Abstract: We demonstrate a new regulatory mechanism in the jasmonic acid (JA) and salicylic acid (SA) mediated crosstalk in potato defense response, wherein,... Read more »

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Antibody Universal Plant ChIP-seq Kit
CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enha...
Published: March, 2022

Abstract: Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but s... Read more »

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IP-Star Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS C...
Published: February, 2022

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »

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Chromatin Profiling (ChIP-seq) Services
Epigenetic integrity of paternal imprints enhances the developmenta...
Published: February, 2022

Abstract: The use of two inhibitors of Mek1/2 and Gsk3β (2i) promotes the generation of mouse diploid and haploid embryonic stem cells (ESCs) from the inner ... Read more »

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Antibody
When left does not seem right: epigenetic and bioelectric differenc...
Published: February, 2022

Abstract: BACKGROUND: During embryogenesis lateral symmetry is broken, giving rise to Left/Right (L/R) breast tissues with distinct identity. L/R-sided breas... Read more »

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Premium RRBS Kit
Comparative Toxicogenomics of Glyphosate and Roundup Herbicidesby M...
Published: February, 2022

Abstract: Whether glyphosate-based herbicides (GBHs) are more potent than glyphosate alone at activating cellular mechanisms, which drive carcinogenesis rema... Read more »

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Premium RRBS Kit
Distinct effects on the secretion of MTRAP and AMA1 in Plasmodium y...
Published: February, 2022

Abstract: Plasmodium, the causative agents of malaria, are obligate intracellular organisms. In humans, pathogenesis is caused by the blood stage parasite, w... Read more »
Comprehensive characterization of the epigenetic landscape in Multi...
Published: January, 2022

Abstract: Background: Human multiple myeloma (MM) cell lines (HMCLs) have been widely used to understand themolecular processes that drive MM biology. Epigen... Read more »

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Antibody Bioruptor Plus IPure kit IP-Star Compact
Comprehensive characterization of the epigenetic landscape in Multi...
Published: January, 2022

Abstract: Background: Human multiple myeloma (MM) cell lines (HMCLs) have been widely used to understand the molecular processes that drive MM biology. Epige... Read more »

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Bioruptor Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
Single-cell-resolved dynamics of chromatin architecture delineate c...
Published: January, 2022

Abstract: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While man... Read more »

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Bioruptor True MicroChIP kit
Human centromere formation activates transcription and opens chroma...
Published: January, 2022

Abstract: Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments l... Read more »

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Antibody
Pre-configuring chromatin architecture with histone modifications g...
Published: January, 2022

Abstract: The gene activity underlying cell differentiation is regulated by a diverse set of transcription factors (TFs), histone modifications, chromatin st... Read more »

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Antibody
NuA4 and H2A.Z control environmental responses and autotrophicgrowt...
Published: January, 2022

Abstract: Nucleosomal acetyltransferase of H4 (NuA4) is an essential transcriptional coactivator in eukaryotes, but remains poorly characterized in plants. H... Read more »

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Antibody Microplex Library Preparation kit
Developmental and Injury-induced Changes in DNA Methylation inRegen...
Published: January, 2022

Abstract: Background Because some of its CNS neurons (e.g., retinal ganglion cells after optic nerve crush (ONC)) regenerate axons throughout life, whereas o... Read more »

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iDeal ChIP-seq Kit for Histones hMeDIP
DNMT1 regulates the timing of DNA methylation by DNMT3 in anenzymat...
Published: January, 2022

Abstract: DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of o... Read more »

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Antibody
MGcount: a total RNA-seq quantification tool to address multi-mappi...
Published: January, 2022

Abstract: Background Total-RNA sequencing (total-RNA-seq) allows the simultaneous study of both the coding and the non-coding transcriptome. Yet, computation... Read more »

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D-Plex small RNA-seq
Coordinated glucocorticoid receptor and MAFB action inducestoleroge...
Published: January, 2022

Abstract: Abstract Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the glucocorticoid receptor (GR). Dendritic cells (DC... Read more »

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Antibody IPure kit
Improved chromosome-level genome assembly of the Glanville fritilla...
Published: January, 2022

Abstract: Abstract Background The Glanville fritillary (Melitaea cinxia) butterfly is a model system for metapopulation dynamics research in fragmented lands... Read more »

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Megaruptor
Bone marrow age dictates clonality of smooth muscle-derived cells i...
Published: January, 2022

Abstract: Aging is the predominant risk factor for atherosclerosis, the leading cause of death. Rare smooth muscle cells (SMCs) clonally expand giving rise t... Read more »
Mod(mdg4) variants repress telomeric retrotransposon HeT-A by block...
Published: January, 2022

Abstract: Telomeres in Drosophila are composed of sequential non-LTR retrotransposons: HeT-A, TART , and TAHRE . Although they are repressed by the piRNA pat... Read more »
Integrating SNPs-based genetic risk factor with blood epigenomic re...
Published: January, 2022

Abstract: Arsenic (As) contamination in groundwater is responsible for numerous adverse health outcomes among millions of people. Epigenetic alterations are ... Read more »
Development and inter-laboratory validation of the VISAGE enhanced ...
Published: January, 2022

Abstract: The analysis of DNA methylation has become an established method for chronological age estimation. This has triggered interest in the forensic comm... Read more »
Loss of KMT2C reprograms the epigenomic landscape in hPSCs resultin...
Published: January, 2022

Abstract: Germline or somatic variation in the family of KMT2 lysine methyltransferases have been associated with a variety of congenital disorders and cance... Read more »
Single cell quantification of ribosome occupancy in early mouse dev...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq
Androgen receptor and MYC equilibration centralizes on developmenta...
Published: December, 2021

Abstract: Androgen receptor (AR) in prostate cancer (PCa) can drive transcriptional repression of multiple genes including MYC, and supraphysiological androg... Read more »

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Antibody
A predominant enhancer co-amplified with the oncogene is necessary...
Published: December, 2021

Abstract: Amplification and overexpression of the SOX2 oncogene represent a hallmark of squamous cancers originating from diverse tissue types. Here, we find... Read more »

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CRISPR

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