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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Coupling Immunoprecipitation with Multiplexed Digital PCR for Cell-...
Published: June, 2025
Abstract: Colorectal cancer (CRC) remains a major global health challenge, with an increasing incidence of early-onset cases among young adults. Targeted... Read more »
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MagMeDIP kit IPure kit
Androgen receptor-mediated assisted loading of the glucocorticoid r...
Published: June, 2025
Abstract: Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biological processes, with significant implication... Read more »
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Tagmentase
Charting the regulatory landscape of TP53 on transposable elements ...
Published: June, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
ATAC-seq in Emerging Model Organisms: Challenges and Strategies
Published: June, 2025
Abstract: The Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) is a versatile and widely utilized method for identifying potential regul... Read more »
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Tagmentase
CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
Published: May, 2025
Abstract: The SWI/SNF (or BAF) complex is an essential chromatin remodeler, which is frequently mutated in cancer and neurodevelopmental disorders. These are... Read more »
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Tagmentase
Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion ...
Published: May, 2025
Abstract: Nucleoporin 98 (NUP98) fusion oncoproteins are strong drivers of pediatric acute myeloid leukemia (AML) with poor prognosis. Here we show that ... Read more »
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CUT&Tag
Charting the regulatory landscape of TP53 on transposable elements ...
Published: May, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Cervicovaginal microbiome alters transcriptomic and epigenomic sign...
Published: May, 2025
Abstract: Background The cervicovaginal microbiome plays a critical role in women's health, with microbial communities dominated by Lactobacillus ... Read more »
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ATAC-seq
Epigenomic disorder and partial EMT impair luminal progenitor integ...
Published: April, 2025
Abstract: In breast cancer related to the BRCA1 mutation, luminal progenitor cells are believed to be the cells of origin, yet how these cells transform into... Read more »
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CUT&Tag
Drug-loaded indocyanine green J-aggregates activate metalloimmunoth...
Published: April, 2025
Abstract: Hepatocellular carcinoma (HCC) poses a significant therapeutic challenge, driving the need for novel treatment strategies. This study investigates ... Read more »
The chromatin reader Dido3 is a regulator of the gene network that ...
Published: April, 2025
Abstract: The development of hematopoietic cell lineages is a highly complex process governed by a delicate interplay of various transcription factors. T... Read more »
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True MicroChIP kit
Epstein-Barr Virus-Driven B-Cell Transformation under Germinal Cent...
Published: April, 2025
Abstract: Epstein-Barr virus (EBV) contributes to over 200,000 cancers annually, predominantly aggressive lymphomas originating from hypoxic germinal centers... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
RNA G-quadruplex removal promotes a translational switch after meio...
Published: April, 2025
Abstract: Oocyte maturation-coupled mRNA post-transcriptional regulation is essential for the establishment of developmental potential. Previously, oocyte mR... Read more »
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D-Plex small RNA-seq
Unified molecular approach for spatial epigenome, transcriptome, an...
Published: April, 2025
Abstract: Spatial epigenomics and multiomics can provide fine-grained insights into cellular states but their widespread adoption is limited by the requireme... Read more »
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Tagmentase
The establishment of nuclear organization in mouse embryos is orche...
Published: April, 2025
Abstract: The folding of the genome in the 3D nuclear space is fundamental for regulating all DNA-related processes. The association of the genome with the... Read more »
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Antibody CUT&Tag
Recurrent spontaneous miscarriages from sperm after ABVD chemothera...
Published: April, 2025
Abstract: Lymphomas represent one of the most common malignant diseases in young men and an important issue is how treatments will affect their reproductive ... Read more »
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Premium RRBS Kit
An ISWI-related chromatin remodeller regulates stage-specific gene ...
Published: April, 2025
Abstract: ATP-dependent chromatin remodellers are specialized multiprotein machines that organize the genome in eukaryotic cells and regulate its accessibili... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors ATAC-seq
Complete sequencing of ape genomes
Published: April, 2025
Abstract: The most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our ... Read more »
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Megaruptor
Menin-MLL1 complex cooperates with NF-Y to promote HCC survival
Published: April, 2025
Abstract: Abstract Identification of new therapeutic targets in hepatocellular carcinoma (HCC) remains critical. Chromatin regulating complexes are frequent... Read more »
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Tagmentase
Embryo-scale single-cell chemical transcriptomics reveals dependenc...
Published: April, 2025
Abstract: Summary Organogenesis is a highly organized process that is conserved across vertebrates and is heavily dependent on intercellular signaling to ac... Read more »
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Tagmentase
Spatial transcriptomic imaging of an intact organism using volumetr...
Published: March, 2025
Abstract: Lymphatic, nervous and tumor tissues exhibit complex physiology arising from three-dimensional interactions within genetically unique microenvironm... Read more »
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Tagmentase
Repression of oxidative phosphorylation by NR2F2, MTERF3 and GDF15 ...
Published: March, 2025
Abstract: Lifestyle factors such as a Western diet or metabolic diseases like diabetes disrupt glucose homeostasis and induce stress responses, yet their imp... Read more »
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ATAC-seq
SIRT6 activator fucoidan extends healthspan and lifespan in aged wi...
Published: March, 2025
Abstract: Abstract SIRT6 is a protein deacylase, deacetylase, and mono-ADP-ribosylase (mADPr) regulating biological pathways important for longevity includi... Read more »
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Tagmentase
HSV-1 infection induces a downstream shift of the +1 nucleosome
Published: March, 2025
Abstract: Herpes simplex virus 1 (HSV-1) infection induces a loss of host transcriptional activity and widespread disruption of host transcription terminatio... Read more »
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Antibody
Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in reg...
Published: March, 2025
Abstract: The histone chaperone and transcription elongation factor SPT6 is integral to RNA polymerase II (RNAPII) activity. SPT6 also plays a crucial role i... Read more »
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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors
Human de novo mutation rates from a four-generation pedigree reference
Published: March, 2025
Abstract: Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five complementary short-read and long-read... Read more »
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Megaruptor
The Utah NeoSeq Project: a collaborative multidisciplinary program ...
Published: March, 2025
Abstract: Rapid genomic diagnostics in the Neonatal Intensive Care Unit represents a paradigm shift in medicine with increasing evidence of the utility of ea... Read more »
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DNA shearing
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ...
Published: March, 2025
Abstract: Microglial diversity arises from the interplay between inherent genetic programs and external environmental signals. However, the mechanisms by whi... Read more »
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iDeal ChIP-seq Kit for Histones
Spatially resolved genome-wide joint profiling of epigenome and tra...
Published: March, 2025
Abstract: The epigenome of a cell is tightly correlated with gene transcription, which controls cell identity and diverse biological activities. Recent advan... Read more »
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Tagmentase CUT&Tag
Cortico-striatal circuit mechanisms drive the effects of D1 dopamin...
Published: March, 2025
Abstract: Working memory capacity (WMC), the number of items remembered in a short-time interval, is regulated by fronto-striatal dopamine (DA) and is re... Read more »
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Bioruptor

イベント

  • 2nd Clinical Genomic Biomarkers Summit
    Basel, Switzerland
    Jun 24, 2025
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