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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Targeting transthyretin by one Cas9 variant with superfidelity and ...
Published: January, 2026
Abstract: Amyloid transthyretin (ATTR) amyloidosis is a fatal disease caused by the accumulation of misfolded transthyretin proteins. Although knocking down ... Read more »
Neurons undergo IFNγ-driven persistent epigenetic shifts and synapt...
Published: December, 2025
Abstract: In infectious and autoimmune disorders of the central nervous system, neurons can become cognate immunological targets of cytotoxic T cells, lead... Read more »
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Antibody True MicroChIP kit ChIPmentation
Adrenergic signaling coordinates distant and local responses to amp...
Published: December, 2025
Abstract: Many species regenerate lost body parts following amputation. Most limb regeneration research has focused on the immediate injury site. Meanwhile... Read more »
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Tagmentase
Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular c...
Published: December, 2025
Abstract: Chromatin regulators are frequently mutated or aberrantly expressed in hepatocellular carcinoma (HCC), suggesting that the dysregulation of chrom... Read more »
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Tagmentase
Antibody-mediated control of anellovirus infection: evidence from p...
Published: December, 2025
Abstract: Infections with viruses belonging to the family Anelloviridae are widespread among humans. Although generally considered a commensal, the... Read more »
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Bioruptor
Helicobacter pylori infection and α-synuclein pathology drive paral...
Published: December, 2025
Abstract: Parkinson’s disease is a common neurodegenerative disease related to both genetic and environmental insults. Epidemiological studies have lin... Read more »
Interphase chromosome conformation is specified by distinct folding...
Published: December, 2025
Abstract: Identity-specific chromosome conformation must be re-established at each cell division. To uncover how interphase folding is inherited, we deve... Read more »
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Tagmentase
Refeeding with different levels of dietary carbohydrate modulates e...
Published: December, 2025
Abstract: The Nile tilapia (Oreochromis niloticus) exhibits a strong metabolic response to dietary carbohydrates (CHO). Short-term refeeding after fasting ... Read more »
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Antibody
High‐Throughput Targeted Sequencing Identifies an HPV Methylation P...
Published: December, 2025
Abstract: High‐risk human papillomavirus (hrHPV) infection is the primary cause of cervical cancer. However, hrHPV testing lacks specificity in detecting neo... Read more »
Protocol for mapping insertion sites of Tol2 transgenes in zebrafis...
Published: December, 2025
Abstract: A valuable and widely utilized approach to study gene regulatory networks is through transgenic lines. However, detailed information of transgene... Read more »
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Tagmentase
Longevity-driven hepatic transcriptional programs mediate resilienc...
Published: November, 2025
Abstract: The liver plays a central role in regulating systemic metabolism, and its function declines with age, contributing to increased susceptibilit... Read more »
Cervicovaginal microbiome alters transcriptomic and chromatin acces...
Published: November, 2025
Abstract: Background: The cervicovaginal microbiome plays a critical role in women's health with microbial communities dominated by Lactobacillus specie... Read more »
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ATAC-seq
Dynamic DNA methylation changes during colorectal oncogenesis with ...
Published: November, 2025
Abstract: The dynamics of colorectal epigenetics within the adenoma stages of oncogenesis remain undocumented. In this study, we investigated DNA methylati... Read more »
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Premium Bisulfite Kit
Cell-free DNA methylation and fragmentomics-based liquid biopsy for...
Published: November, 2025
Abstract: Background Cell-free DNA is a promising source of biomarkers for early cancer detection and carries tumor-driven methylation and fragmentation f... Read more »
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MagMeDIP kit
Targeted sequencing and iterative assembly of near-complete genomes
Published: November, 2025
Abstract: Complete telomere-to-telomere diploid genome assemblies have long posed significant challenges due to the intricate architecture of genomes. In dip... Read more »
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Megaruptor
Conserved heat shock factors HvHSFA2 and HvHSFA3 control barley hea...
Published: November, 2025
Abstract: Climate change requires optimizing stress responses in crops. Priming and memory of heat stress (HS) allow plants to improve their tolerance ag... Read more »
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Antibody
Antagonizing epigenetically controlled PAF/PAF-R pathway improves l...
Published: November, 2025
Abstract: Background and aims Platelet-activating factor (PAF) phospholipid is mainly produced by macrophages and involved in pro-inflammatory responses. We... Read more »
Refined ChIP‐Seq Protocol for High‐Quality Chromatin Profiling in S...
Published: November, 2025
Abstract: The chromatin immunoprecipitation followed by sequencing (ChIP‐seq) assay is an instrumental and accurate method for understanding chromatin dynami... Read more »
Human iPSCs-based modeling unveils SETBP1 as a driver of chromatin ...
Published: November, 2025
Abstract: Patients with GATA2 deficiency are predisposed to developing myelodysplastic neoplasms (MDS), which can progress to acute myeloid leukemia. Thi... Read more »
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Tagmentase
Tel1 is recruited at chromosomal loop/axis contact sites to modulat...
Published: November, 2025
Abstract: During meiosis, the programmed formation of DNA double-strand breaks (DSBs) by Spo11, a conserved topoisomerase VI family protein, initiates ho... Read more »
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IPure kit
Mucinous cystic neoplasms of the pancreas demonstrate in situ produ...
Published: November, 2025
Abstract: Introduction Mucinous cystic neoplasms (MCNs) are rare cystic tumors that may occur in the liver, pancreas, or retroperitoneum, defined histolog... Read more »
PRC1-mediated H2A.Zub promotes gene expression by preventing H3.1K2...
Published: November, 2025
Abstract: Background: PcG complexes are pivotal in orchestrating the transition from embryonic to vegetative development in plants. However, the mechani... Read more »
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Antibody
DNA methylation dynamics associated with visual system remodeling d...
Published: November, 2025
Abstract: Background: Flatfish metamorphosis involves dramatic tissue remodeling, including the migration of one eye to the opposite side of the body, e... Read more »
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Premium RRBS Kit
Epstein-Barr virus-transformed B-cells from a hypoxia model of the ...
Published: November, 2025
Abstract: Epstein-Barr virus (EBV) drives over 200,000 cancer cases annually, including diffuse large B-cell lymphoma, Burkitt lymphoma, and classic Hodg... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Sox8 is essential for vertebrate gastrulation
Published: November, 2025
Abstract: Gastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the precise orchestratio... Read more »
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Antibody
Stage-specific transcriptomic and DNA methylation responses to trip...
Published: November, 2025
Abstract: Background: Polyploidy, the condition of having more than two chromosome sets, is relatively common in plants but rare in animals, largely due... Read more »
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Premium RRBS Kit
PRKG1 hinders myogenic differentiation and predicts response to AKT...
Published: November, 2025
Abstract: Rhabdomyosarcoma (RMS) is marked by a myogenesis differentiation blockade, and while the AKT/mTOR pathway is universally activated, its pharmac... Read more »
EZHIP restricts noncanonical PRC2 binding and regulates H3K27me3 in...
Published: November, 2025
Abstract: In mice, the repressive histone mark H3K27me3 undergoes both region-specific inheritance and erasure during the parental-to-embryonic transition,... Read more »
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D-Plex small RNA-seq
Epigenomics of embryogenesis in turbot
Published: November, 2025
Abstract: Embryogenesis is the foundational step of ontogeny, where a complex organism emerges from a single totipotent cell. This process is orchestrate... Read more »
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Antibody ChIPmentation
Single-cell, multi-region profiling of the macaque brain across the...
Published: November, 2025
Abstract: Brain aging is a complex process with profound health and societal consequences. However, the molecular and cellular pathways that govern its tem... Read more »
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Tagmentase

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