Publications
Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.
Oxidative stress causes a reversible decrease of deubiquitylases ac...
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Population differences of chromosome 22q11.2 duplication structure ...
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
A single small molecule-based human embryo model reveals V-ATPase r...
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
Stage-specific epigenetic priming amplifies gene activation during ...
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Dissociation Between Metabolic Improvements and Mitochondrial Trans...
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
chromIDEAS reveals epigenetic dynamics via multi-dimensional cluste...
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Exon inclusion signatures enable accurate estimation of splicing fa...
Published: March, 2026
Abstract: Splicing factors control exon inclusion in messenger RNAs, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by m... Read more »
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Bioruptor Plus
Published: March, 2026
Abstract: Splicing factors control exon inclusion in messenger RNAs, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by m... Read more »
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Bioruptor Plus
A repeat expansion in GOLGA8A is a major risk factor for atypical f...
Published: March, 2026
Abstract: Atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions (aFTLD-U) is neuropathologically characterized by aggregation of the ... Read more »
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Megaruptor
Published: March, 2026
Abstract: Atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions (aFTLD-U) is neuropathologically characterized by aggregation of the ... Read more »
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Megaruptor
The effects of ingested cellulose nanomaterials on DNA methylation ...
Published: March, 2026
Abstract: Background: Cellulose nanomaterials (CNMs) are emerging materials under development for various applications in biomedicine and the food indus... Read more »
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Premium RRBS Kit
Published: March, 2026
Abstract: Background: Cellulose nanomaterials (CNMs) are emerging materials under development for various applications in biomedicine and the food indus... Read more »
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Premium RRBS Kit
Proteomic landscape of Ewing sarcoma primary tumors and metastases
Published: March, 2026
Abstract: Ewing sarcoma (EWS), a rare pediatric bone tumor, poses unique therapeutic challenges due to its distinct microenvironment and limited molecular un... Read more »
Published: March, 2026
Abstract: Ewing sarcoma (EWS), a rare pediatric bone tumor, poses unique therapeutic challenges due to its distinct microenvironment and limited molecular un... Read more »
Epithelial sensing of vitamin A shapes intestinal antimicrobial def...
Published: March, 2026
Abstract: Vitamin A is a central regulator of intestinal adaptive immunity, but its role in innate immunity is less defined. Antimicrobial proteins form a ch... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Published: March, 2026
Abstract: Vitamin A is a central regulator of intestinal adaptive immunity, but its role in innate immunity is less defined. Antimicrobial proteins form a ch... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Genome-wide discovery of cis-regulatory elements in a large genome
Published: March, 2026
Abstract: Identifying non-coding regulatory elements in the genome poses a challenge in most organisms. Classical methods rely on trial and error to test t... Read more »
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Tagmentase
Published: March, 2026
Abstract: Identifying non-coding regulatory elements in the genome poses a challenge in most organisms. Classical methods rely on trial and error to test t... Read more »
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Tagmentase
Direct interaction of ribosomes with postsynaptic proteins gives ri...
Published: February, 2026
Abstract: Ribosomes and thousands of mRNAs are localized near synapses to support local protein synthesis. Little is known, however, about how ribosomes ar... Read more »
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D-Plex small RNA-seq
Published: February, 2026
Abstract: Ribosomes and thousands of mRNAs are localized near synapses to support local protein synthesis. Little is known, however, about how ribosomes ar... Read more »
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D-Plex small RNA-seq
SIRT1 mediates brain metabolic and developmental consequences of me...
Published: February, 2026
Abstract: Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological d... Read more »
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Premium RRBS Kit
Published: February, 2026
Abstract: Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological d... Read more »
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Premium RRBS Kit
Functional dissection of complex trait variants at single-nucleotid...
Published: February, 2026
Abstract: Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core problem in human genetics1-5. Most of thes... Read more »
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Tagmentase
Published: February, 2026
Abstract: Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core problem in human genetics1-5. Most of thes... Read more »
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Tagmentase
Repeat-rich RNA guides repetitive genomic elements into biomolecula...
Published: February, 2026
Abstract: Biomolecular condensation is a pivotal mechanism in chromatin organization and nuclear compartmentalization. However, the molecular mechanism t... Read more »
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Tagmentase
Published: February, 2026
Abstract: Biomolecular condensation is a pivotal mechanism in chromatin organization and nuclear compartmentalization. However, the molecular mechanism t... Read more »
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Tagmentase
Genetic regulation across germline and somatic variation on the Y c...
Published: February, 2026
Abstract: Our understanding of the biological role of the Y chromosome remains limited. Here, we systematically profile germline Y haplogroups and somatic lo... Read more »
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Megaruptor
Published: February, 2026
Abstract: Our understanding of the biological role of the Y chromosome remains limited. Here, we systematically profile germline Y haplogroups and somatic lo... Read more »
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Megaruptor
Methylome and transcriptome responses to feed stress induced by low...
Published: February, 2026
Abstract: Background Poultry farming provides an important source of protein for human consumption around the world. Improving chicken adaptation to changin... Read more »
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Premium RRBS Kit
Published: February, 2026
Abstract: Background Poultry farming provides an important source of protein for human consumption around the world. Improving chicken adaptation to changin... Read more »
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Premium RRBS Kit
Hypoxic stress granules trigger immunogenic dormancy in lung cancer
Published: February, 2026
Abstract: Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for eff... Read more »
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Antibody
Published: February, 2026
Abstract: Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for eff... Read more »
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Antibody
HIF sustain a transcriptional regulatory circuit of EPAS1 expressio...
Published: February, 2026
Abstract: Initiation and sustainment of oncogenic signaling is a hallmark of cancer evolution and progression. In renal clear cell carcinoma, loss of von... Read more »
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CUT&Tag
Published: February, 2026
Abstract: Initiation and sustainment of oncogenic signaling is a hallmark of cancer evolution and progression. In renal clear cell carcinoma, loss of von... Read more »
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CUT&Tag
Epigenetic regulation of serine biosynthesis by PHF8 during neuroge...
Published: February, 2026
Abstract: Progenitor proliferation during neurodevelopment requires tight coordination of epigenetic regulation and metabolism. However, the crosstalk betw... Read more »
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ChIP Cross-link Gold
Published: February, 2026
Abstract: Progenitor proliferation during neurodevelopment requires tight coordination of epigenetic regulation and metabolism. However, the crosstalk betw... Read more »
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ChIP Cross-link Gold
Comparative multi-omics of the macrophage response to infection wit...
Published: February, 2026
Abstract: Background Bovine tuberculosis (bTB) is a chronic infectious disease primarily caused by Mycobacterium bovis, which inflicts significan... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services
Published: February, 2026
Abstract: Background Bovine tuberculosis (bTB) is a chronic infectious disease primarily caused by Mycobacterium bovis, which inflicts significan... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services
Non-disruptive in vitro monitoring of cellular states with cell-fre...
Published: February, 2026
Abstract: Individual CpG methylation signatures characterize each mammalian cell type, thereby offering a powerful readout for clinical and diagnostic applic... Read more »
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Megaruptor
Published: February, 2026
Abstract: Individual CpG methylation signatures characterize each mammalian cell type, thereby offering a powerful readout for clinical and diagnostic applic... Read more »
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Megaruptor
Acute NIPBL depletion reveals in vivo dynamics of loop extrusion an...
Published: February, 2026
Abstract: The organization of the genome in three-dimensional space is highly dynamic, yet how these dynamics are regulated and the role they play in gen... Read more »
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Microplex Library Preparation kit
Published: February, 2026
Abstract: The organization of the genome in three-dimensional space is highly dynamic, yet how these dynamics are regulated and the role they play in gen... Read more »
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Microplex Library Preparation kit
Ononin Sensitizes Papillary Thyroid Carcinoma Cells to Cisplatin by...
Published: February, 2026
Abstract: Ononin, a natural isoflavone glycoside, has demonstrated antitumor activity in several malignancies, but its role in papillary thyroid carcinoma ... Read more »
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iDeal ChIP-qPCR
Published: February, 2026
Abstract: Ononin, a natural isoflavone glycoside, has demonstrated antitumor activity in several malignancies, but its role in papillary thyroid carcinoma ... Read more »
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iDeal ChIP-qPCR
Higher order repeat structures reflect diverging evolutionary paths...
Published: February, 2026
Abstract: Background: Highly repetitive tandem repeat arrays, known as satellite DNAs, are enriched in low-recombination regions such as centromeres. Sa... Read more »
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Megaruptor
Published: February, 2026
Abstract: Background: Highly repetitive tandem repeat arrays, known as satellite DNAs, are enriched in low-recombination regions such as centromeres. Sa... Read more »
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Megaruptor
High-quality genome sequence of five Antarctic actinomycetes: Micro...
Published: February, 2026
Abstract: Micromonospora ureilytica DSM 120150, Nocardiopsis akebiae DSM 120151, Streptomyces fildesensis DSM 41987T, Streptomy... Read more »
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Megaruptor
Published: February, 2026
Abstract: Micromonospora ureilytica DSM 120150, Nocardiopsis akebiae DSM 120151, Streptomyces fildesensis DSM 41987T, Streptomy... Read more »
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Megaruptor
Microglia-Derived Extracellular Vesicles from Alzheimer's Disease P...
Published: February, 2026
Abstract: Alzheimer's disease (AD) represents the most common cause of dementia and urgently requires sensitive biomarkers and effective therapies. Extrace... Read more »
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D-Plex small RNA-seq
Published: February, 2026
Abstract: Alzheimer's disease (AD) represents the most common cause of dementia and urgently requires sensitive biomarkers and effective therapies. Extrace... Read more »
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D-Plex small RNA-seq
CUT homeobox factors modulate chromatin accessibility in neurons
Published: February, 2026
Abstract: Abstract Neuronal identity relies on coordinated transcriptional programs that include both neuron type-specific features and broadly shared pan-n... Read more »
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Tagmentase
Published: February, 2026
Abstract: Abstract Neuronal identity relies on coordinated transcriptional programs that include both neuron type-specific features and broadly shared pan-n... Read more »
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Tagmentase
Unbalanced chromatin binding of Polycomb complexes drives neurodeve...
Published: February, 2026
Abstract: Abstract The prevalence of neurodevelopmental disorders (NDDs) in children is increasing, yet their underlying causes remain largely unknown. We... Read more »
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ChIP Cross-link Gold
Published: February, 2026
Abstract: Abstract The prevalence of neurodevelopmental disorders (NDDs) in children is increasing, yet their underlying causes remain largely unknown. We... Read more »
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ChIP Cross-link Gold