Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors
Published: May, 2021

Abstract: Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Semi... Read more »

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D-Plex small RNA-seq
Vesicle-bound regulatory RNAs are associated with tissue aging
Published: May, 2021

Abstract: Previous work on murine models and human demonstrated global as well as tissue-specific molecular aging trajectories in solid tissues and body flui... Read more »

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D-Plex RNA-seq kit
HOTAIR lncRNA promotes epithelial-mesenchymal transition byredistri...
Published: May, 2021

Abstract: Epithelial-to-mesenchymal transition (EMT) describes the loss of epithelial traits and gain of mesenchymal traits by normal cells during developmen... Read more »

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Antibody
The lncRNA and the transcription factor WRKY42 target common cell ...
Published: May, 2021

Abstract: Plant long noncoding RNAs (lncRNAs) are key chromatin dynamics regulators, directing the transcriptional programs driving a wide variety of develop... Read more »

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Antibody
Placental uptake and metabolism of 25(OH)Vitamin D determines itsac...
Published: May, 2021

Abstract: Pregnancy 25-hydroxyvitamin D (25(OH)D) concentrations are associated with maternal and fetal health outcomes, but the underlying mechanisms have n... Read more »

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Antibody
Chromatin accessibility governs the differential response of cancer...
Published: May, 2021

Abstract: Depleting the microenvironment of important nutrients such as arginine is a key strategy for immune evasion by cancer cells. Many tumors overexpres... Read more »

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Antibody
Sarcomere function activates a p53-dependent DNA damage response th...
Published: May, 2021

Abstract: Human cardiac regeneration is limited by low cardiomyocyte replicative rates and progressive polyploidization by unclear mechanisms. To study this ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Published: May, 2021

Abstract: Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to so... Read more »

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Antibody
Contrasting epigenetic control of transgenes and endogenous genes p...
Published: May, 2021

Abstract: Transgenes that are stably expressed in plant genomes over many generations could be assumed to behave epigenetically the same as endogenous genes.... Read more »
Identification of a PadR-type regulator essential for intracellular...
Published: May, 2021

Abstract: Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease endemic to the tropics. Melioidosis manifests in various ways rangi... Read more »
Epigenomic profiling of primate lymphoblastoid cell lines reveals t...
Published: May, 2021

Abstract: Changes in the epigenetic regulation of gene expression have a central role in evolution. Here, we extensively profiled a panel of human, chimpanze... Read more »
GATA6 defines endoderm fate by controlling chromatin accessibility ...
Published: May, 2021

Abstract: SUMMARY In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their... Read more »
The SAM domain-containing protein 1 (SAMD1) acts as a repressive ch...
Published: May, 2021

Abstract: CpG islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive... Read more »
MeCP2 controls neural stem cell fate specification through miR-199a...
Published: May, 2021

Abstract: Rett syndrome (RTT) is a severe neurological disorder, with impaired brain development caused by mutations in MECP2; however, the underlying mechan... Read more »
Simplification of culture conditions and feeder-free expansion of b...
Published: May, 2021

Abstract: Bovine embryonic stem cells (bESCs) extend the lifespan of the transient pluripotent bovine inner cell mass in vitro. After years of research, deri... Read more »
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at ...
Published: April, 2021

Abstract: Analyzing all features of small non-coding RNA sequencing data can be demanding and challenging. To facilitate this process, we developed miRMaster... Read more »

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small non-coding RNA sequencing analysis microRNA miRNA prediction bioinformatic tools D-Plex RNA-seq kit
Enhanced cell deconvolution of peripheral blood using DNA methylati...
Published: April, 2021

Abstract: DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution ... Read more »

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DNA methylation microarray Immune profiling
Interplay between Histone and DNA Methylation Seen through Comparat...
Published: April, 2021

Abstract: DNA methylation (DNAme) profiling is used to establish specific biomarkers to improve the diagnosis of patients with inherited neurodevelopmental d... Read more »

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Rare diseases Neurodevelopment disorders DNA methylation microarray Biomarker discovery
Muscle allele-specific expression QTLs may affect meat quality trai...
Published: April, 2021

Abstract: Single nucleotide polymorphisms (SNPs) located in transcript sequences showing allele-specific expression (ASE SNPs) were previously identified in ... Read more »
Androgen and glucocorticoid receptor direct distinct transcriptiona...
Published: April, 2021

Abstract: The glucocorticoid (GR) and androgen (AR) receptors execute unique functions in vivo, yet have nearly identical DNA binding specificities. To ident... Read more »

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Antibody
Chromosomal inversion polymorphisms in two sympatric ascidian linea...
Published: April, 2021

Abstract: Chromosomal rearrangements can reduce fitness of heterozygotes and can thereby prevent gene flow. Therefore, such rearrangements can play a role in... Read more »

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Megaruptor
USP22 Suppresses Expression in Acute Colitis and Inflammation-Asso...
Published: April, 2021

Abstract: As a member of the 11-gene "death-from-cancer" gene expression signature, ubiquitin-specific protease 22 (USP22) has been considered an oncogene in... Read more »

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Antibody
PCIP-seq: simultaneous sequencing of integrated viral genomes and t...
Published: April, 2021

Abstract: The integration of a viral genome into the host genome has a major impact on the trajectory of the infected cell. Integration location and variatio... Read more »

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Megaruptor
Waves of sumoylation support transcription dynamics during adipocyt...
Published: April, 2021

Abstract: Tight control of gene expression networks required for adipose tissue formation and plasticity is essential for adaptation to energy needs and envi... Read more »

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Microplex Library Preparation kit
Sensitive and reproducible cell-free methylome quantification with ...
Published: April, 2021

Abstract: Background. Cell-free methylated DNA immunoprecipitation-sequencing (cfMeDIP-seq) identifies genomic regions with DNA methylation, using a protocol... Read more »

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Antibody
Complex-dependent histone acetyltransferase activity of KAT8 determ...
Published: April, 2021

Abstract: Acetylation of lysine 16 on histone H4 (H4K16ac) is catalyzed by histone acetyltransferase KAT8 and can prevent chromatin compaction in vitro.... Read more »

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Antibody
The anti-inflammatory cytokine interleukin-37 is an inhibitor of tr...
Published: April, 2021

Abstract: Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/macrophages by exposure to pathogens or vaccines, which evolv... Read more »

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Antibody
Androgen receptor positively regulates gonadotropin-releasing hormo...
Published: April, 2021

Abstract: Within pituitary gonadotropes, the gonadotropin-releasing hormone receptor (GnRHR) receives hypothalamic input from GnRH neurons that is critical f... Read more »

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ChIP Cross-link Gold
Dynamic association of the H3K64 trimethylation mark with genes enc...
Published: April, 2021

Abstract: Epigenetic modifications have emerged as critical regulators of virulence genes and stage-specific gene expression in Plasmodium falciparum. Howeve... Read more »

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Antibody
Multi-omics phenotyping of the gut-liver axis reveals metabolicpert...
Published: April, 2021

Abstract: Health effects of pesticides are not always accurately detected using the current battery of regulatory toxicity tests. We compared standard histop... Read more »

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