Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A histone H3.3K36M mutation in mice causes an imbalance of histonem...
Published: November, 2020

Abstract: Histone lysine-to-methionine (K-to-M) mutations have been identified as driver mutations in human cancers. Interestingly, these 'oncohistone' mutat... Read more »

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Antibody
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation a...
Published: November, 2020

Abstract: The discovery of H3K27M mutations in pediatric gliomas marked a new chapter in cancer epigenomics. Numerous studies have investigated the effect of... Read more »

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IP-Star Compact iDeal ChIP-seq Kit for Histones
BCG Vaccination Induces Long-Term Functional Reprogramming of Human...
Published: November, 2020

Abstract: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous infections, probably via induction of non-specifi... Read more »

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Antibody
TRF2 Mediates Replication Initiation within Human Telomeres to Prev...
Published: November, 2020

Abstract: The telomeric shelterin protein telomeric repeat-binding factor 2 (TRF2) recruits origin recognition complex (ORC) proteins, the foundational build... Read more »

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Antibody
Macrophage Immune Memory Controls Endometriosis in Mice and Humans.
Published: November, 2020

Abstract: Endometriosis is a frequent, chronic, inflammatory gynecological disease characterized by the presence of ectopic endometrial tissue causing pain a... Read more »

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iDeal ChIP-seq Kit for Histones
MEAF6 is essential for cell proliferation and plays a role in theas...
Published: November, 2020

Abstract: Myst family genes encode lysine acetyltransferases that mainly mediate histone acetylation to control transcription, DNA replication and DNA damage... Read more »

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Antibody
CDK4/6 inhibition reprograms the breast cancer enhancer landscape b...
Published: November, 2020

Abstract: Pharmacologic inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6) were designed to induce cancer cell cycle arrest. Recent studies have suggest... Read more »

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Antibody
ZNF354C is a transcriptional repressor that inhibits endothelialang...
Published: November, 2020

Abstract: Zinc finger proteins (ZNF) are a large group of transcription factors with diverse functions. We recently discovered that endothelial cells harbour... Read more »

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Antibody Beads
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS C...
Published: October, 2020

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALSCom...
Published: October, 2020

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »
Mechanism of delayed seed germination caused by high temperature du...
Published: October, 2020

Abstract: High temperature during grain filling considerably reduces yield and quality in rice (Oryza sativa L.); however, how high temperature affects seed ... Read more »

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MagMeDIP kit
Contrasting signatures of genomic divergence during sympatric speci...
Published: October, 2020

Abstract: The transition from 'well-marked varieties' of a single species into 'well-defined species'-especially in the absence of geographic barriers to gen... Read more »

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Megaruptor
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ...
Published: October, 2020

Abstract: Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethy... Read more »
The histone H2B ubiquitin ligase RNF40 is required for HER2-drivenm...
Published: October, 2020

Abstract: The HER2-positive breast cancer subtype (HER2-BC) displays a particularly aggressive behavior. Anti-HER2 therapies have significantly improved the ... Read more »

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Antibody Microplex Library Preparation kit
RUNX3 methylation drives hypoxia-induced cell proliferation andanti...
Published: October, 2020

Abstract: Inactivation of tumor suppressor Runt-related transcription factor 3 (RUNX3) plays an important role during early tumorigenesis. However, posttrans... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
StE(z)2, a Polycomb group methyltransferase and deposition of H3K27...
Published: October, 2020

Abstract: Polycomb Repressive Complex (PRC) group proteins regulate various developmental processes in plants by repressing the target genes via H3K27 trimet... Read more »

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Antibody
Priming for enhanced ARGONAUTE2 activation accompanies induced resi...
Published: October, 2020

Abstract: Systemic acquired resistance (SAR) is a broad-spectrum disease resistance response that can be induced upon infection from pathogens or by chemical... Read more »

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Antibody
Digging Deeper into Breast Cancer Epigenetics: Insights from Chemic...
Published: October, 2020

Abstract: Breast cancer is often sporadic due to several factors. Among them, the deregulation of epigenetic proteins may be involved. TIP60 or KAT5 is an ac... Read more »

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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
Genome-wide DNA methylation analysis using MethylCap-seq in canineh...
Published: October, 2020

Abstract: DNA methylation is a comprehensively studied epigenetic modification and plays crucial roles in cancer development. In the present study, MethylCap... Read more »

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MethylCap
Polycomb Repressive Complex 2-mediated histone modification H3K27me...
Published: October, 2020

Abstract: Epigenetic reprogramming during germ cell formation is essential to gain pluripotency and thus embryogenic potential. The histone modification H3K2... Read more »

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Microplex Library Preparation kit
Genome structure and content of the rice root-knot nematode ().
Published: October, 2020

Abstract: Discovered in the 1960s, is a root-knot nematode species considered as a major threat to rice production. Yet, its origin, genomic structure, and i... Read more »

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Megaruptor
Transcription of CLDND1 in human brain endothelial cells is regulat...
Published: October, 2020

Abstract: Increased permeability of endothelial cells lining the blood vessels in the brain leads to vascular oedema and, potentially, to stroke. The tight j... Read more »

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OneDay ChIP Kit
Benchmarking DNA methylation assays in a reef-building coral.
Published: October, 2020

Abstract: Interrogation of chromatin modifications, such as DNA methylation, has the potential to improve forecasting and conservation of marine ecosystems. ... Read more »

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MethylCap
Super-enhancer switching drives a burst in gene expression at themi...
Published: October, 2020

Abstract: Owing to bursts in the expression of thousands of germline-specific genes, the testis has the most diverse and complex transcriptome of all organs.... Read more »

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IP-Star Compact
NSD1-deposited H3K36me2 directs de novo methylation in the mouse ma...
Published: October, 2020

Abstract: De novo DNA methylation (DNAme) in mammalian germ cells is dependent on DNMT3A and DNMT3L. However, oocytes and spermatozoa show distinct patterns ... Read more »

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Antibody
Repeat expansions confer WRN dependence in microsatellite-unstablec...
Published: October, 2020

Abstract: The RecQ DNA helicase WRN is a synthetic lethal target for cancer cells with microsatellite instability (MSI), a form of genetic hypermutability th... Read more »

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Megaruptor
MITF is a driver oncogene and potential therapeutic target in kidne...
Published: October, 2020

Abstract: Tuberous sclerosis complex (TSC) is an autosomal dominant tumor suppressor syndrome, characterized by tumor development in multiple organs, includi... Read more »

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Antibody
Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Gr...
Published: October, 2020

Abstract: Trained immunity, a functional state of myeloid cells, has been proposed as a compelling immune-oncological target. Its efficient induction require... Read more »

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Antibody
Epigenetic Blockade of Hippocampal SOD2 Via DNMT3b-Mediated DNAMeth...
Published: October, 2020

Abstract: The recurrent events of mild trauma exacerbate the vulnerability for post-traumatic stress disorder; however, the underlying molecular mechanisms a... Read more »

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Antibody
p53 directly represses human LINE1 transposons.
Published: October, 2020

Abstract: p53 is a potent tumor suppressor and commonly mutated in human cancers. Recently, we demonstrated that p53 genes act to restrict retrotransposons i... Read more »

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Antibody

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  • Virtual ChIP workshop - January 18-19, 2022 or January 25-26, 2022
    Diagenode
    Jan 18-Jan 26, 2022
  • Virtual DNA Methylation - January 18-19, 2022 or January 25-26, 2022
    Diagenode
    Jan 18-Jan 26, 2022
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    Lausanne, Switzerland
    Feb 14-Feb 15, 2022
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