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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

TGFα Promotes Chemoresistance of Malignant Pleural Mesothelioma.
Published: June, 2020

Abstract: : There is no standard chemotherapy for refractory or relapsing malignant pleural mesothelioma (MPM). Our previous reports nevertheless indicated t... Read more »

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CATS
A conserved RNA degradation complex required for spreading and epig...
Published: June, 2020

Abstract: Heterochromatic domains containing histone H3 lysine 9 methylation (H3K9me) can be epigenetically inherited independently of underlying DNA sequenc... Read more »

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Antibody
Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is ...
Published: June, 2020

Abstract: Before zygotic genome activation (ZGA), the quiescent genome undergoes reprogramming to transition into the transcriptionally active state. However... Read more »

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Antibody
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of m...
Published: June, 2020

Abstract: We have generated mouse models of malignant mesothelioma (MM) based upon disruption of the Bap1, Nf2, and Cdkn2ab tumor suppressor loci in various ... Read more »

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iDeal ChIP-seq Kit for Histones
Inactivation of Arid1a in the endometrium is associated with endome...
Published: June, 2020

Abstract: Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidat... Read more »

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ChIP Cross-link Gold
A Germline Mutation in the Gene Is a Candidate for Familial Non-Me...
Published: June, 2020

Abstract: Non-medullary thyroid cancer (NMTC) is a common endocrine malignancy with a genetic basis that has yet to be unequivocally established. In a recent... Read more »

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IPure kit
AXR1 affects DNA methylation independently of its role in regulatin...
Published: June, 2020

Abstract: Meiotic crossovers (COs) are important for reshuffling genetic information between homologous chromosomes and they are essential for their correct ... Read more »

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Antibody
Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforc...
Published: May, 2020

Abstract: BACKGROUND: The histone 3 lysine 4 (H3K4) monomethylase KMT2C is mutated across several cancer types; however, the effects of mutations on epigenom... Read more »

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iDeal ChIP-seq Kit for Histones
The 20S proteasome activator PA28γ controls the compaction of chrom...
Published: May, 2020

Abstract: The nuclear PA28γ is known to activate the 20S proteasome, but its precise cellular functions remains unclear. Here, we identify PA28γ ... Read more »

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Antibody
Integration of high-throughput reporter assays identify a critical ...
Published: May, 2020

Abstract: The Ikzf1 locus encodes the lymphoid specific transcription factor Ikaros, which plays an essential role in both T and B cell differentiation, whil... Read more »

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Antibody
Measuring Histone Modifications in the Human Parasite Schistosoma m...
Published: May, 2020

Abstract: DNA-binding proteins play critical roles in many major processes such as development and sexual biology of Schistosoma mansoni and are important fo... Read more »

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IP-Star Antibody
Histone post-translational modifications in Silene latifolia X and ...
Published: May, 2020

Abstract: Silene latifolia is a model organism to study evolutionary young heteromorphic sex chromosome evolution in plants. Previous research indicates a Y-... Read more »

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Antibody
AP-1 controls the p11-dependent antidepressant response.
Published: May, 2020

Abstract: Selective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed drugs for mood disorders. While the mechanism of SSRI action is stil... Read more »

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Antibody Beads ChIP Cross-link Gold
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-...
Published: May, 2020

Abstract: Despite the clinical success of Androgen Receptor (AR)-targeted therapies, reactivation of AR signalling remains the main driver of castration-resi... Read more »

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Antibody IP-Star Compact
Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis I...
Published: May, 2020

Abstract: Somatic stem cells expand massively during tissue regeneration, which might require control of cell fitness, allowing elimination of non-competitiv... Read more »

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Antibody
β-Glucan Induces Protective Trained Immunity against Mycobacterium ...
Published: May, 2020

Abstract: β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called "trained immunity," resulting... Read more »

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Antibody
DNA methylation enzymes and PRC1 restrict B-cell Epstein-Barr virus...
Published: May, 2020

Abstract: To accomplish the remarkable task of lifelong infection, the Epstein-Barr virus (EBV) switches between four viral genome latency and lytic programm... Read more »

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MagMeDIP kit Antibody
DNA methylation variation in the brain of laying hens in relation t...
Published: May, 2020

Abstract: Domesticated animals are unique to investigate the contribution of genetic and non-genetic factors to specific phenotypes. Among non-genetic factor... Read more »

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Antibody
MYC transcription activation mediated by OCT4 as a mechanism of res...
Published: May, 2020

Abstract: Despite the improvement in clinical outcome with 13-cis-retinoic acid (13-cisRA) + anti-GD2 antibody + cytokine immunotherapy given in first respon... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
TET3 controls the expression of the H3K27me3 demethylase Kdm6b duri...
Published: May, 2020

Abstract: The acquisition of cell identity is associated with developmentally regulated changes in the cellular histone methylation signatures. For instance,... Read more »

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Antibody
Repeat RNAs associate with replication forks and post-replicative DNA.
Published: May, 2020

Abstract: Non-coding RNA has a proven ability to direct and regulate chromatin modifications by acting as scaffolds between DNA and histone-modifying complex... Read more »
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming...
Published: May, 2020

Abstract: Follicular lymphomas (FLs) are slow-growing, indolent tumors containing extensive follicular dendritic cell (FDC) networks and recurrent EZH2 gain-... Read more »

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Microplex Library Preparation kit True MicroChIP kit
Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and th...
Published: May, 2020

Abstract: Accumulating evidence points to a significant link between disrupted circadian rhythms and neuronal disfunctions, though the molecular mechanisms u... Read more »

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Antibody
Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage o...
Published: May, 2020

Abstract: A basic question linked to differential patterns of gene expression is how cells reach different fates despite using the same DNA template. Since 5... Read more »

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MagMeDIP kit
Revisiting promyelocytic leukemia protein targeting by human cytome...
Published: May, 2020

Abstract: Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, centra... Read more »

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Antibody
In vitro capture and characterization of embryonic rosette-stage pl...
Published: May, 2020

Abstract: Following implantation, the naive pluripotent epiblast of the mouse blastocyst generates a rosette, undergoes lumenogenesis and forms the primed pl... Read more »

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Antibody
The domesticated transposase ALP2 mediates formation of a novel Pol...
Published: May, 2020

Abstract: A large fraction of plant genomes is composed of transposable elements (TE), which provide a potential source of novel genes through "domestication... Read more »

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Antibody
Genomic Profiling by ALaP-Seq Reveals Transcriptional Regulation by...
Published: April, 2020

Abstract: The promyelocytic leukemia (PML) body is a phase-separated nuclear structure physically associated with chromatin, implying its crucial roles in ge... Read more »

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Antibody
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloi...
Published: April, 2020

Abstract: Tissue-resident and recruited macrophages contribute to both host defense and pathology. Multiple macrophage phenotypes are represented in diseased... Read more »

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Antibody
SETDB2 promoted breast cancer stem cell maintenance by interaction ...
Published: April, 2020

Abstract: The histone H3K9 methyltransferase SETDB2 is involved in cell cycle dysregulation in acute leukemia and has oncogenic roles in gastric cancer. In o... Read more »

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Antibody

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