Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Combined Analysis of mRNA Expression and Open Chromatin in Microglia
Published: August, 2023

Abstract: The advance of single-cell RNA-sequencing technologies in the past years has enabled unprecedented insights into the complexity and heterogeneity o... Read more »

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Tagmentase
Volumetric imaging of an intact organism by a distributed molecular...
Published: August, 2023

Abstract: Lymphatic, nervous, and tumoral tissues, among others, exhibit physiology that emerges from three-dimensional interactions between genetically uniq... Read more »

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Tagmentase
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »

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Newly added
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »
Cerebrospinal fluid methylome-based liquid biopsies for accuratemal...
Published: August, 2023

Abstract: BACKGROUND: Resolving the differential diagnosis between brain metastases (BM), glioblastomas (GBM), and central nervous system lymphomas (CNSL) is... Read more »

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MagMeDIP kit IPure kit
Nuclear proinflammatory cytokine S100A9 enhances expression of huma...
Published: August, 2023

Abstract: Transcription of the human papillomavirus (HPV) oncogenes, and , is regulated by the long control region (LCR) of the viral genome. Although vario... Read more »

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Newly added
A high-throughput screening assay for silencing established HIV-1 m...
Published: August, 2023

Abstract: HIV-infected macrophages are long-lived cells that represent a barrier to functional cure. Additionally, low-level viral expression by central nerv... Read more »

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Newly added
Transgenerational endocrine disruptor effects of cadmium in zebrafi...
Published: August, 2023

Abstract: Evidence has emerged that environmentally-induced epigenetic changes can have long-lasting effects on gene transcription across generations. These ... Read more »

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MagMeDIP kit
Transcription factor EGR2 controls homing and pathogenicity of T17c...
Published: August, 2023

Abstract: CD4 T helper 17 (T17) cells protect barrier tissues but also trigger autoimmunity. The mechanisms behind these opposing processes remain unclear. H... Read more »

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CUT&Tag
ThPOK is a critical multifaceted regulator of myeloid lineagedevelo...
Published: August, 2023

Abstract: The transcription factor ThPOK (encoded by Zbtb7b) is well known for its role as a master regulator of CD4 lineage commitment in the thymus. Here, ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
Differentiation block in acute myeloid leukemia regulated by intron...
Published: August, 2023

Abstract: Iroquois transcription factor gene IRX3 is highly expressed in 20–30\% of acute myeloid leukemia (AML) and contributes to the pa... Read more »

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MagMeDIP kit IPure kit Microplex Library Preparation kit ChIP Cross-link Gold
Zfp296 knockout enhances chromatin accessibility and induces a uniq...
Published: July, 2023

Abstract: The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following dif... Read more »

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Perturbed epigenetic transcriptional regulation in AML with IDH mut...
Published: July, 2023

Abstract: Isocitrate dehydrogenase (IDH) mutations are found in 20\% of acute myeloid leukemia (AML) patients. However, only 30-40\% of the patients respond ... Read more »

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Newly added
Zfp296 knockout enhances chromatin accessibility and induces a uniq...
Published: July, 2023

Abstract: The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following dif... Read more »

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Antibody Tagmentase
Mediator 1 ablation induces enamel-to-hair lineage conversion in mi...
Published: July, 2023

Abstract: Postnatal cell fate is postulated to be primarily determined by the local tissue microenvironment. Here, we find that Mediator 1 (Med1) dependent e... Read more »

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IPure kit iDeal ChIP-seq Kit for Transcription Factors
CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c inHCT116...
Published: July, 2023

Abstract: The miR-34a and miR-34b/c encoding genes represent direct targets of the p53 transcription factor, and presumably mediate part of the tumor suppres... Read more »

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iDeal ChIP-qPCR
Perturbed epigenetic transcriptional regulation in AML with IDHmuta...
Published: July, 2023

Abstract: Isocitrate dehydrogenase (IDH) mutations are found in 20\% of acute myeloid leukemia (AML) patients. However, only 30-40\% of the patients respond ... Read more »

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Infinium Human MethylationEPIC Array Service
Carnobacterium maltaromaticum boosts intestinal vitamin D productio...
Published: July, 2023

Abstract: Carnobacterium maltaromaticum was found to be specifically depleted in female patients with colorectal cancer (CRC). Administration of C.Â&nb... Read more »

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Antibody
Enhanced frequency of transcription pre-initiation complexes assemb...
Published: July, 2023

Abstract: In addition to being essential for gene expression, transcription is crucial for the maintenance of genome integrity. Here, we undertook a systemat... Read more »

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Antibody
ALDH1A1 promotes PARP inhibitor resistance by enhancing retinoic ac...
Published: July, 2023

Abstract: Poly (ADP-ribose) Polymerase (PARP) inhibitors (PARPi) have been approved for both frontline and recurrent setting in ovarian cancer with homologou... Read more »

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Antibody
Opposing gene regulatory programs governing myofiber development an...
Published: July, 2023

Abstract: Skeletal muscle fibers express distinct gene programs during development and maturation, but the underlying gene regulatory networks that confer st... Read more »

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Antibody
Alterations in the hepatocyte epigenetic landscape in steatosis.
Published: July, 2023

Abstract: Fatty liver disease or the accumulation of fat in the liver, has been reported to affect the global population. This comes with an increased risk f... Read more »

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Antibody
SMYD3 represses tumor-intrinsic interferon response in HPV-negative...
Published: July, 2023

Abstract: Cancers often display immune escape, but the mechanisms are incompletely understood. Herein, we identify SMYD3 as a mediator of immune escape in hu... Read more »

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Antibody
DeSUMOylation of chromatin-bound proteins limits the rapidtranscrip...
Published: July, 2023

Abstract: Genotoxicants have been used for decades as front-line therapies against cancer on the basis of their DNA-damaging actions. However, some of their ... Read more »

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Antibody
RNA polymerase II CTD is dispensable for transcription and required...
Published: July, 2023

Abstract: The largest subunit of RNA polymerase (Pol) II harbors an evolutionarily conserved C-terminal domain (CTD), composed of heptapeptide repeats, centr... Read more »

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Antibody
Net39 protects muscle nuclei from mechanical stress during thepatho...
Published: July, 2023

Abstract: Mutations in genes encoding nuclear envelope proteins lead to diseases known as nuclear envelopathies, characterized by skeletal muscle and heart a... Read more »

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Antibody
Single-cell quantification of ribosome occupancy in early mouse dev...
Published: June, 2023

Abstract: Translation regulation is critical for early mammalian embryonic development1. However, previous studies had been restricted to bulk measurements2,... Read more »

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D-Plex small RNA-seq
The NF-Y splicing signature controls hybrid EMT and ECM-related pat...
Published: June, 2023

Abstract: Aberrant splicing events are associated with colorectal cancer (CRC) and provide new opportunities for tumor diagnosis and treatment. The expressio... Read more »

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Newly added
Targeting lymphoid-derived IL-17 signaling to delay skin aging.
Published: June, 2023

Abstract: Skin aging is characterized by structural and functional changes that contribute to age-associated frailty. This probably depends on synergy betwee... Read more »

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ChIP Cross-link Gold
Polycomb protein SCML2 mediates paternal epigenetic inheritance thr...
Published: June, 2023

Abstract: Sperm chromatin retains small amounts of histones, and chromatin states of sperm mirror gene expression programs of the next generation. However, i... Read more »

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Antibody

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