Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The histone modification H3K4me3 is altered at the locus in Alzhei...
Published: February, 2021

Abstract: Several epigenome-wide association studies of DNA methylation have highlighted altered DNA methylation in the gene in Alzheimer's disease (AD) brai... Read more »

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Antibody
Alterations of DNA Methylation Caused by Cold Plasma Treatment Rest...
Published: February, 2021

Abstract: In rice (Oryza sativa L.), seeds exposed to heat stress during grain filling exhibit delayed germination because of DNA methylation levels at promo... Read more »

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MagMeDIP kit
REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERICMODULATOR
Published: February, 2021

Abstract: Canonical targeting of Polycomb Repressive Complex 1 (PRC1) to repress developmental genes is mediated by cell type-specific, paralogous chromobox ... Read more »

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Antibody
Germline activity of the heat shock factor HSF-1 programs theinsuli...
Published: February, 2021

Abstract: The mechanisms by which maternal stress alters offspring phenotypes remain poorly understood. Here we report that the heat shock transcription fact... Read more »

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Antibody
The G2-phase enriched lncRNA SNHG26 is necessary for proper cell cy...
Published: February, 2021

Abstract: Long noncoding RNAs (lncRNAs) are involved in the regulation of cell cycle, although only a few have been functionally characterized. By combining ... Read more »

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Antibody
STAG proteins promote cohesin ring loading at R-loops
Published: February, 2021

Abstract: Most studies of cohesin function consider the Stromalin Antigen (STAG/SA) proteins as core complex members given their ubiquitous interaction with ... Read more »

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Antibody
Restricted nucleation and piRNA-mediated establishment of heterochr...
Published: February, 2021

Abstract: Heterochromatin is a key architectural feature of eukaryotic genomes, crucial for silencing of repetitive elements and maintaining genome stability... Read more »

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Antibody
The epigenetic landscape in purified myonuclei from fast and slow m...
Published: February, 2021

Abstract: Muscle cells have different phenotypes adapted to different usage and can be grossly divided into fast/glycolytic and slow/oxidative types. While m... Read more »

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Antibody
Environmental enrichment induces epigenomic and genome organization...
Published: February, 2021

Abstract: In early development, the environment triggers mnemonic epigenomic programs resulting in memory and learning experiences to confer cognitive phenot... Read more »

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Antibody
Chromatin dysregulation associated with NSD1 mutation in head and n...
Published: February, 2021

Abstract: Chromatin dysregulation has emerged as an important mechanism of oncogenesis. To develop targeted treatments, it is important to understand the tra... Read more »

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Antibody Bioruptor Plus IP-Star Compact
Kmt2c mutations enhance HSC self-renewal capacity and convey a sele...
Published: February, 2021

Abstract: The myeloid tumor suppressor KMT2C is recurrently deleted in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), particularly therapy-... Read more »

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Antibody
The glucocorticoid receptor recruits the COMPASS complex to regulat...
Published: February, 2021

Abstract: Glucocorticoids (GCs) are effective anti-inflammatory drugs; yet, their mechanisms of action are poorly understood. GCs bind to the glucocorticoid ... Read more »

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Antibody
A distinct metabolic response characterizes sensitivity to EZH2inhi...
Published: February, 2021

Abstract: Multiple myeloma (MM) is a heterogeneous haematological disease that remains clinically challenging. Increased activity of the epigenetic silencer ... Read more »

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iDeal ChIP-seq Kit for Histones
A brain cyst load-associated antigen is a Toxoplasma gondii biomark...
Published: February, 2021

Abstract: BACKGROUND: Biomarker discovery remains a major challenge for predictive medicine, in particular, in the context of chronic diseases. This is true ... Read more »

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IPure kit iDeal ChIP-seq Kit for Histones
BAF complexes drive proliferation and block myogenic differentiatio...
Published: January, 2021

Abstract: Rhabdomyosarcoma (RMS) is a pediatric malignancy of skeletal muscle lineage. The aggressive alveolar subtype is characterized by t(2;13) or t(1;13)... Read more »

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Chromatin Shearing iDeal ChIP-seq Kit for Transcription Factors
A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia
Published: January, 2021

Abstract: Long-range oncogenic enhancers play an important role in cancer. Yet, whether similar regulation of tumor suppressor genes is relevant remains uncl... Read more »

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Antibody IP-Star Compact
Developmental cannabidiol exposure increases anxiety and modifies g...
Published: January, 2021

Abstract: BACKGROUND: Use of cannabidiol (CBD), the primary non-psychoactive compound found in cannabis, has recently risen dramatically, while relatively li... Read more »
JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.ZAcety...
Published: January, 2021

Abstract: Histone variants differ in amino acid sequence, expression timing and genomic localization sites from canonical histones and convey unique function... Read more »

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Microplex Library Preparation kit
Genomic Characterization of VIM and MCR Co-Producers: The First Two...
Published: January, 2021

Abstract: BACKGROUND: the co-production of carbapenemases and -genes represents a worrisome event in the treatment of infections. The aim of the study was to... Read more »

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Megaruptor
Epigenetic impairment and blunted transcriptional response to Mycob...
Published: January, 2021

Abstract: Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of recent infection with Mycobacte... Read more »

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Microplex Library Preparation kit
IGFBP2 protects against pulmonary fibrosis through inhibiting P21-m...
Published: January, 2021

Abstract: Accumulation of senescent cells contributes to age related diseases including idiopathic pulmonary fibrosis (IPF). Insulin-like growth factor bindi... Read more »

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DNA Methylation Profiling (RRBS Service)
Perturbed DNA methylation by sustained overexpression of Gadd45b in...
Published: January, 2021

Abstract: Heterochromatin disorganization is a key hallmark of aging and DNA methylation state is currently the main molecular predictor of chronological age... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Stronger induction of trained immunity by mucosal BCG or MTBVAC vac...
Published: January, 2021

Abstract: BCG vaccination can strengthen protection against pathogens through the induction of epigenetic and metabolic reprogramming of innate immune cells,... Read more »

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Antibody
FOS licenses early events in stem cell activation driving skeletal ...
Published: January, 2021

Abstract: Muscle satellite cells (SCs) are a quiescent (non-proliferative) stem cell population in uninjured skeletal muscle. Although SCs have been investig... Read more »

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iDeal ChIP-qPCR
The Essential Function of SETDB1 in Homologous Chromosome Pairing a...
Published: January, 2021

Abstract: SETDB1 is a histone-lysine N-methyltransferase critical for germline development. However, its function in early meiotic prophase I remains unknown... Read more »

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Antibody
Detection of genetic variation and base modifications at base-pairr...
Published: January, 2021

Abstract: Accurate decoding of nucleic acid variation is critical to understand the complexity and regulation of genome function. Here we use a single-molecu... Read more »

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Antibody
Histone demethylase JMJD2B/KDM4B regulates transcriptional program ...
Published: January, 2021

Abstract: Trophoblast stem cell (TSC) is crucial to the formation of placenta in mammals. Histone demethylase JMJD2 (also known as KDM4) family proteins have... Read more »

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Microplex Library Preparation kit
Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage.
Published: January, 2021

Abstract: HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed underst... Read more »

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Antibody
The Identification of a Novel Fucosidosis-Associated Mutation: A C...
Published: January, 2021

Abstract: Fucosidosis is a rare neurodegenerative autosomal recessive disorder, which manifests as progressive neurological and psychomotor deterioration, gr... Read more »

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Premium RRBS Kit
Chromosome-scale genome assembly provides insights into the evoluti...
Published: January, 2021

Abstract: Passion fruit (Passiflora edulis Sims) is an economically valuable fruit that is cultivated in tropical and subtropical regions of the world. Here,... Read more »

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Megaruptor

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