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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

DNA Methylation Editing by CRISPR-guided Excision of 5-Methylcytosine.
Published: February, 2020

Abstract: Tools for actively targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epig... Read more »

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Antibody CRISPR
STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural R...
Published: February, 2020

Abstract: Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that this process can be induced in mous... Read more »

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LowCell ChIP kit
LncRNA np_5318 promotes renal ischemia‑reperfusion injury through t...
Published: February, 2020

Abstract: Long noncoding (Lnc)RNA np_5318 has been proved to be involved in renal injury, while its functionality in renal ischemia‑reperfusion (I/R) injury ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Widespread loss of the silencing epigenetic mark H3K9me3 in astrocy...
Published: February, 2020

Abstract: BACKGROUND: Hexanucleotide repeat expansions of the GC motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotr... Read more »

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Antibody
Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexat...
Published: February, 2020

Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes pain and swelling of multiple joints in the body. The underlying disease mech... Read more »

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Premium RRBS Kit
Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor An...
Published: February, 2020

Abstract: Increased rates of locoregional recurrence (LR) have been observed in triple negative breast cancer (TNBC) despite multimodality therapy, including... Read more »

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HighCell ChIP kit IPure kit
MYCN amplification and ATRX mutations are incompatible in neuroblas...
Published: February, 2020

Abstract: Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neurobl... Read more »

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iDeal ChIP-seq Kit for Histones
Inhibition of methyltransferase activity of enhancer of zeste 2 lea...
Published: February, 2020

Abstract: BACKGROUND: Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This sus... Read more »

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Antibody
REDOX RESPONSIVE TRANSCRIPTION FACTOR1 (RRFT1) is involved in extra...
Published: February, 2020

Abstract: Extracellular ATP (eATP) is an apoplastic signaling molecule that plays essential roles in the growth and development of plants. Arabidopsis seedli... Read more »

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ChIP-seq
Targeting Macrophage Histone H3 Modification as a Leishmania Strate...
Published: February, 2020

Abstract: Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity. A better understan... Read more »

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Antibody
Smad anchor for receptor activation nuclear localization during dev...
Published: February, 2020

Abstract: Smad anchor for receptor activation (SARA, zfyve9) has been classically observed in early endosomes of different cells types where it regulates ves... Read more »

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ChIP-qPCR
Host-Specific Evolutionary and Transmission Dynamics Shape the Func...
Published: February, 2020

Abstract: Metagenomic inferences of bacterial strain diversity and infectious disease transmission studies largely assume a dominant, within-individual haplo... Read more »

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Megaruptor
Threonine phosphorylation of IκBζ mediates inhibition of selective ...
Published: February, 2020

Abstract: Transcription factors of the NF-κB family play a crucial role for immune responses by activating the expression of chemokines, cytokines and ... Read more »

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Antibody
Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oo...
Published: February, 2020

Abstract: In mammals, chromatin organization undergoes drastic reorganization during oocyte development. However, the dynamics of three-dimensional chromatin... Read more »

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Antibody
Long non-coding RNA uc.291 controls epithelial differentiation by i...
Published: February, 2020

Abstract: The mechanisms that regulate the switch between epidermal progenitor state and differentiation are not fully understood. Recent findings indicate t... Read more »

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Antibody
Tissue alarmins and adaptive cytokine induce dynamic and distinct t...
Published: February, 2020

Abstract: The respective effects of tissue alarmins interleukin (IL)-15 and interferon beta (IFNβ), and IL-21 produced by T cells on the reprogramming o... Read more »

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Antibody
Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencepha...
Published: February, 2020

Abstract: Granulins (GRN) are secreted factors that promote neuronal survival and regulate inflammation in various pathological conditions. However, their ro... Read more »

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Microplex Library Preparation kit
An inferred fitness consequence map of the rice genome.
Published: February, 2020

Abstract: The extent to which sequence variation impacts plant fitness is poorly understood. High-resolution maps detailing the constraint acting on the geno... Read more »

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Microplex Library Preparation kit
Genome Sequence of sp. Strain JOR-1, an Extremely Halophilic Archa...
Published: January, 2020

Abstract: An extremely halophilic archaeon, sp. strain JOR-1, was isolated from the east coast of the Dead Sea, Kingdom of Jordan, and sequenced using single... Read more »

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Megaruptor
Pro-death signaling of cytoprotective heat shock factor 1: upregula...
Published: January, 2020

Abstract: Heat shock can induce either cytoprotective mechanisms or cell death. We found that in certain human and mouse cells, including spermatocytes, acti... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Replicational Dilution of H3K27me3 in Mammalian Cells and the Role ...
Published: January, 2020

Abstract: Polycomb repressive complex 2 (PRC2) places H3K27me3 at developmental genes and is causally implicated in keeping bivalent genes silent. It is uncl... Read more »

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Antibody
The round goby genome provides insights into mechanisms that may fa...
Published: January, 2020

Abstract: BACKGROUND: The invasive benthic round goby (Neogobius melanostomus) is the most successful temperate invasive fish and has spread in aquatic ecosy... Read more »

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Megaruptor
Preterm birth is associated with epigenetic programming of transgen...
Published: January, 2020

Abstract: Renal and cardiovascular complications of prematurity are well established, notably the development of hypertension in adulthood. However, the unde... Read more »

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MagMeDIP kit
Inhibition of histone deacetylation rescues phenotype in a mouse mo...
Published: January, 2020

Abstract: Mutations in the actively expressed, maternal allele of the imprinted KCNK9 gene cause Birk-Barel intellectual disability syndrome (BBIDS). Using a... Read more »

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Antibody Beads
Heterochromatin protein 1γ deficiency decreases histone H3K27 methy...
Published: January, 2020

Abstract: Heterochromatin protein (HP) 1γ, a component of heterochromatin in eukaryotes, is involved in H3K9 methylation. Although HP1γ is expres... Read more »

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LowCell ChIP kit
A multiplexed gRNA piggyBac transposon system facilitates efficient...
Published: January, 2020

Abstract: CRISPR-Cas9-mediated gene interference (CRISPRi) and activation (CRISPRa) approaches hold promise for functional gene studies and genome-wide scree... Read more »

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HighCell ChIP kit
The complete mitochondrial genome of Taxus cuspidata (Taxaceae): ei...
Published: January, 2020

Abstract: BACKGROUND: Gymnosperms represent five of the six lineages of seed plants. However, most sequenced plant mitochondrial genomes (mitogenomes) have b... Read more »

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Megaruptor
miR-155 inhibits mitophagy through suppression of BAG5, a partner p...
Published: January, 2020

Abstract: Removal of dysfunctional mitochondria is essential step to maintain normal cell physiology, and selective autophagy in mitochondria, called mitopha... Read more »

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Antibody
Dual-initiation promoters with intertwined canonical and TCT/TOP tr...
Published: January, 2020

Abstract: Variations in transcription start site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcriptional RNA fate... Read more »

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Microplex Library Preparation kit
Multisite Evaluation of Next-Generation Methods for Small RNA Quant...
Published: January, 2020

Abstract: Small RNAs (smRNAs) are important regulators of many biologic processes and are now most frequently characterized using Illumina sequencing. Howeve... Read more »

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CATS

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