Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Ren...
Published: August, 2020

Abstract: Diabetic kidney disease (DKD) is a major complication of diabetes and the leading cause of end-stage renal failure. Epigenetics has been associated... Read more »

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Antibody
Exploring the virulence gene interactome with CRISPR/dCas9 in the h...
Published: August, 2020

Abstract: Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have ... Read more »

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Bioruptor Antibody Microplex Library Preparation kit
Targeted bisulfite sequencing for biomarker discovery.
Published: August, 2020

Abstract: Cytosine methylation is one of the best studied epigenetic modifications. In mammals, DNA methylation patterns vary among cells and is mainly found... Read more »

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Bioruptor
Tissue-Specific In Vivo Biotin Chromatin Immunoprecipitation withSe...
Published: July, 2020

Abstract: Chromatin immunoprecipitation with sequencing (ChIP-seq) has been instrumental in understanding transcription factor (TF) binding during gene regul... Read more »

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Microplex Library Preparation kit
The gut microbiome switches mutant p53 from tumour-suppressive toon...
Published: July, 2020

Abstract: Somatic mutations in p53, which inactivate the tumour-suppressor function of p53 and often confer oncogenic gain-of-function properties, are very c... Read more »

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Microplex Library Preparation kit
Distinct and temporary-restricted epigenetic mechanisms regulate hu...
Published: July, 2020

Abstract: The development of TCRαβ and TCRγδ T cells comprises a step-wise process in which regulatory events control differentiation ... Read more »

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ChIP-seq Antibody
OxLDL-mediated immunologic memory in endothelial cells.
Published: July, 2020

Abstract: Trained innate immunity describes the metabolic reprogramming and long-term proinflammatory activation of innate immune cells in response to differ... Read more »

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Antibody
Sizing, stabilising, and cloning repeat-expansions for gene targeti...
Published: July, 2020

Abstract: Aberrant microsatellite repeat-expansions at specific loci within the human genome cause several distinct, heritable, and predominantly neurologica... Read more »

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Megaruptor
Integrated epigenetic biomarkers in circulating cell-free DNA as a ...
Published: July, 2020

Abstract: BACKGROUND: The high lethal rate of pancreatic cancer is partly due to a lack of efficient biomarkers for screening and early diagnosis. We attempt... Read more »

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MagMeDIP kit IPure kit
The CDK4/6-EZH2 pathway is a potential therapeutic target for psori...
Published: July, 2020

Abstract: Psoriasis is a frequent inflammatory skin disease characterized by keratinocyte hyperproliferation and a disease-related infiltration of immune cel... Read more »

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Antibody
The Human Integrator Complex Facilitates Transcriptional Elongation...
Published: July, 2020

Abstract: Transcription by RNA polymerase II (RNAPII) is pervasive in the human genome. However, the mechanisms controlling transcription at promoters and en... Read more »

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Antibody ChIP Cross-link Gold
Prostate cancer reactivates developmental epigenomic programs durin...
Published: July, 2020

Abstract: Epigenetic processes govern prostate cancer (PCa) biology, as evidenced by the dependency of PCa cells on the androgen receptor (AR), a prostate ma... Read more »

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Antibody
MeCP2 regulates gene expression through recognition of H3K27me3.
Published: July, 2020

Abstract: MeCP2 plays a multifaceted role in gene expression regulation and chromatin organization. Interaction between MeCP2 and methylated DNA in the ... Read more »

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Antibody
Epigenetic, transcriptional and phenotypic responses in Daphnia mag...
Published: July, 2020

Abstract: Ionizing radiation is known to induce oxidative stress and DNA damage as well as epigenetic effects in aquatic organisms. Epigenetic changes can be... Read more »

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Antibody
Egr2-guided histone H2B monoubiquitination is required for peripher...
Published: July, 2020

Abstract: Schwann cells are the nerve ensheathing cells of the peripheral nervous system. Absence, loss and malfunction of Schwann cells or their myelin shea... Read more »

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Antibody Microplex Library Preparation kit
Translating GWAS-identified loci for cardiac rhythm and rate using ...
Published: July, 2020

Abstract: A meta-analysis of genome-wide association studies (GWAS) identified eight loci that are associated with heart rate variability (HRV), but candidat... Read more »

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Megaruptor
Genomic Insight of VIM-harboring IncA Plasmid from a Clinical ST69E...
Published: July, 2020

Abstract: Background: VIM (Verona Integron-encoded Metallo-beta-lactamase) is a member of the Metallo-Beta-Lactamases (MBLs), and is able to hydrolyze all be... Read more »

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Megaruptor
Molecular Characterization and Event-Specific Real-Time PCR Detecti...
Published: July, 2020

Abstract: Petunia plants with unusual orange flowers were noticed on the European market and confirmed to be genetically modified (GM) by the Finnish authori... Read more »

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Master Mix
Premature termination codons in the gene cause reduced local mRNA ...
Published: July, 2020

Abstract: Duchenne muscular dystrophy (DMD) is caused by mutations in the gene leading to the presence of premature termination codons (PTC). Previous transc... Read more »

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Antibody
Battle of the sex chromosomes: competition between X- and Y-chromos...
Published: July, 2020

Abstract: Transmission distorters (TDs) are genetic elements that favor their own transmission to the detriments of others. Slx/Slxl1 (Sycp3-like-X-linked an... Read more »

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Bioruptor Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services
Identification of Novel Molecular Markers of Human Th17 Cells.
Published: July, 2020

Abstract: Th17 cells are important players in host defense against pathogens such as , , and . Th17 cell-mediated inflammation, under certain conditions in w... Read more »

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Antibody
ACTL6A suppresses p21 expression to enhance the epidermal squamous ...
Published: July, 2020

Abstract: Epidermal squamous cell carcinoma (SCC) is a common and highly invasive form of cancer. SCC arises due to ultraviolet light exposure and is associa... Read more »

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LowCell ChIP kit
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic polyunsat...
Published: July, 2020

Abstract: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent aryl hydrocarbon receptor (AhR) agonist that elicits a broad spectrum of dose-dependent hepa... Read more »

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Microplex Library Preparation kit
FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-en...
Published: June, 2020

Abstract: Fixed-tissue ChIP-seq for H3K27 acetylation (H3K27ac) profiling (FiTAc-seq) is an epigenetic method for profiling active enhancers and promoters in... Read more »

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Antibody
Chronic cannabidiol alters genome-wide DNA methylation in adult mou...
Published: June, 2020

Abstract: Cannabidiol (CBD) is the primary non-psychoactive compound found in cannabis (Cannabis sativa) and an increasingly popular dietary supplement as a ... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Early Life Exposure to Environmentally Relevant Levels of Endocrine...
Published: June, 2020

Abstract: The inland silverside, Menidia beryllina, is a euryhaline fish and a model organism in ecotoxicology. We previously showed that exposure to picomol... Read more »

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Premium RRBS Kit
The hypomethylation of imprinted genes in IVF/ICSI placenta samples...
Published: June, 2020

Abstract: Although more and more children are born by Assisted Reproductive Technologies (ART), ART safety has not fully been demonstrated. Notably, ART coul... Read more »

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Antibody
Detection and discrimination of intracranial tumors using plasma ce...
Published: June, 2020

Abstract: Definitive diagnosis of intracranial tumors relies on tissue specimens obtained by invasive surgery. Noninvasive diagnostic approaches provide an o... Read more »

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MagMeDIP kit Antibody
Detection of renal cell carcinoma using plasma and urine cell-free ...
Published: June, 2020

Abstract: Improving early cancer detection has the potential to substantially reduce cancer-related mortality. Cell-free methylated DNA immunoprecipitation a... Read more »

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MagMeDIP kit Antibody IPure kit
Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi...
Published: June, 2020

Abstract: How the epigenetic landscape is established in development is still being elucidated. Here, we uncover developmental pluripotency associated 2 and ... Read more »

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Antibody Microplex Library Preparation kit

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