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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

TET3 prevents terminal differentiation of adult NSCs by a non-catal...
Published: April, 2019

Abstract: Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, altho... Read more »

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Antibody
Dissecting the role of H3K27 acetylation and methylation in PRC2 me...
Published: April, 2019

Abstract: The Polycomb repressive complexes PRC1 and PRC2 act non-redundantly at target genes to maintain transcriptional programs and ensure cellular identi... Read more »

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Antibody
Essential Gene Profiles for Human Pluripotent Stem Cells Identify U...
Published: April, 2019

Abstract: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding... Read more »

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Antibody
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphoc...
Published: April, 2019

Abstract: Increased glycolysis parallels immune cell activation, but the role of pyruvate remains largely unexplored. We found that stimulation of dendritic ... Read more »

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Antibody
Identification of ADGRE5 as discriminating MYC target between Burki...
Published: April, 2019

Abstract: BACKGROUND: MYC is a heterogeneously expressed transcription factor that plays a multifunctional role in many biological processes such as cell pro... Read more »

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Antibody
A TetR-family transcription factor regulates fatty acid metabolism ...
Published: April, 2019

Abstract: Fatty acid metabolism and its regulation are known to play important roles in bacteria and eukaryotes. By contrast, although certain archaea appear... Read more »

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IPure kit
Assessment and site-specific manipulation of DNA (hydroxy-)methylat...
Published: April, 2019

Abstract: Dynamic changes in DNA (hydroxy-)methylation are fundamental for stem cell differentiation. However, the signature of these epigenetic marks in spe... Read more »

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MagMeDIP kit
The FZD7-TWIST1 axis is responsible for anoikis resistance and tumo...
Published: April, 2019

Abstract: Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD... Read more »

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Antibody
Mitochondrial stress triggers a pro-survival response through epige...
Published: April, 2019

Abstract: Mitochondrial dysfunction represents an important cellular stressor and when intense and persistent cells must unleash an adaptive response to prev... Read more »

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Premium RRBS Kit
Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Ph...
Published: April, 2019

Abstract: CAF-1 is an evolutionarily conserved H3/H4 histone chaperone that plays a key role in replication-coupled chromatin assembly and is targeted to the... Read more »

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Antibody
Kdm6b regulates context-dependent hematopoietic stem cell self-rene...
Published: April, 2019

Abstract: The histone demethylase KDM6B (JMJD3) is upregulated in blood disorders, suggesting that it may have important pathogenic functions. Here we examin... Read more »

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Antibody
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human ...
Published: March, 2019

Abstract: Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcripti... Read more »

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Antibody
Restriction-site associated DNA sequencing supports a sister group ...
Published: March, 2019

Abstract: The orchid genus Nigritella is closely related to Gymnadenia and has from time to time been merged with the latter. Although Nigritella is morpholo... Read more »
Biocompatible N-acetyl cysteine reduces graphene oxide and persists...
Published: March, 2019

Abstract: We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced ... Read more »

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Megaruptor
Point mutations in the PDX1 transactivation domain impair human β-c...
Published: March, 2019

Abstract: OBJECTIVE: Hundreds of missense mutations in the coding region of PDX1 exist; however, if these mutations predispose to diabetes mellitus is unknow... Read more »

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Antibody Microplex Library Preparation kit
H3K27M induces defective chromatin spread of PRC2-mediated repressi...
Published: March, 2019

Abstract: Lys-27-Met mutations in histone 3 genes (H3K27M) characterize a subgroup of deadly gliomas and decrease genome-wide H3K27 trimethylation. Here we u... Read more »

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IP-Star Compact iDeal ChIP-seq Kit for Histones
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transiti...
Published: March, 2019

Abstract: Humoral immunity depends on efficient activation of B cells and their subsequent differentiation into antibody-secreting cells (ASCs). The transcri... Read more »

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Bioruptor
TF-ChIP Method for Tissue-Specific Gene Targets.
Published: March, 2019

Abstract: Chromatin immunoprecipitation (ChIP) is an assay developed in order to define the dynamic nature of transcription processes. This method has been w... Read more »

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Bioruptor
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prost...
Published: March, 2019

Abstract: Androgen deprivation therapy for prostate cancer (PCa) benefits patients with early disease, but becomes ineffective as PCa progresses to a castrat... Read more »

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Antibody
Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Defici...
Published: March, 2019

Abstract: Increasingly effective therapies targeting the androgen receptor have paradoxically promoted the incidence of neuroendocrine prostate cancer (NEPC)... Read more »

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Antibody
A critical regulator of Bcl2 revealed by systematic transcript disc...
Published: March, 2019

Abstract: Normal T-cell differentiation requires a complex regulatory network which supports a series of maturation steps, including lineage commitment, T-ce... Read more »

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Antibody Microplex Library Preparation kit
Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in ...
Published: March, 2019

Abstract: Developing and adult tissues use different cis-regulatory elements. Although DNA at some decommissioned embryonic enhancers is hypomethylated in ad... Read more »

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Antibody
DMSO induces drastic changes in human cellular processes and epigen...
Published: March, 2019

Abstract: Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity in the 1960s, later, the FDA classified DMSO in the ... Read more »

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MagMeDIP kit
The role of TCF3 as potential master regulator in blastemal Wilms t...
Published: March, 2019

Abstract: Wilms tumors are the most common type of pediatric kidney tumors. While the overall prognosis for patients is favorable, especially tumors that exh... Read more »

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Antibody
lncRNA KHPS1 Activates a Poised Enhancer by Triplex-Dependent Recru...
Published: March, 2019

Abstract: Transcription of the proto-oncogene SPHK1 is regulated by KHPS1, an antisense RNA that activates SPHK1 expression by forming a triple-helical RNA-D... Read more »

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Antibody
Transcriptome-wide dynamics of extensive m6A mRNA methylation durin...
Published: March, 2019

Abstract: Malaria pathogenesis results from the asexual replication of Plasmodium falciparum within human red blood cells, which relies on a precisely timed ... Read more »

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Bioruptor Microplex Library Preparation kit
R-Loops Enhance Polycomb Repression at a Subset of Developmental Re...
Published: March, 2019

Abstract: R-loops are three-stranded nucleic acid structures that form during transcription, especially over unmethylated CpG-rich promoters of active genes.... Read more »

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Antibody
Maintenance of MYC expression promotes de novo resistance to BET br...
Published: March, 2019

Abstract: The BET bromodomain protein BRD4 is a chromatin reader that regulates transcription, including in cancer. In prostate cancer, specifically, the ant... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Ezh2 controls development of natural killer T cells, which cause sp...
Published: March, 2019

Abstract: BACKGROUND: Natural killer T (NKT) cells express a T-cell receptor that recognizes endogenous and environmental glycolipid antigens. Several subset... Read more »

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Antibody
Genetic, Inflammatory, and Epithelial Cell Differentiation Factors ...
Published: March, 2019

Abstract: Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that... Read more »

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IP-Star Compact

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