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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Plant species-specific basecaller improves actual accuracy of nanop...
Published: September, 2022
Abstract: Long-read sequencing platforms offered by Oxford Nanopore Technologies (ONT) allow native DNA containing epigenetic modifications to be directly se... Read more »
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Megaruptor
Spatial profiling of chromatin accessibility in mouse and human tis...
Published: August, 2022
Abstract: Cellular function in tissue is dependent on the local environment, requiring new methods for spatial mapping of biomolecules and cells in the ... Read more »
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Tagmentase
A complex epigenome-splicing crosstalk governs epithelial-to-mesenc...
Published: August, 2022
Abstract: Epithelial-to-mesenchymal transition (EMT) renders epithelial cells migratory properties. While epigenetic and splicing changes have been implicate... Read more »
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Bioruptor Antibody
Vitamin D receptor and STAT6 interactome governs oesophagealepithel...
Published: August, 2022
Abstract: OBJECTIVE: The contribution of vitamin D (VD) deficiency to the pathogenesis of allergic diseases remains elusive. We aimed to define the impact of... Read more »
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Antibody IP-Star Compact
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent...
Published: August, 2022
Abstract: Although originally described as transcriptional activator, SPI1/PU.1, a major player in haematopoiesis whose alterations are associated with haema... Read more »
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Microplex Library Preparation kit
Complete Genome Sequences of the Soil Oxalotrophic BacteriumCupriav...
Published: August, 2022
Abstract: Here, we report the complete genome sequences of the soil oxalotrophic bacterium Cupriavidus oxalaticus Ox1 and a derived mCherry-tagged strain. Th... Read more »
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Megaruptor
cfDNA methylome profiling for detection and subtyping of small cell...
Published: August, 2022
Abstract: Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcr... Read more »
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DNA Methylation
The improved genome of the nematode Parapristionchus giblindavisipr...
Published: August, 2022
Abstract: Nematodes such as Caenorhabditis elegans and Pristionchus pacificus are extremely successful model organisms for comparative biology. Several studi... Read more »
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Megaruptor
The chromosome-level genome of Gypsophila paniculata reveals themol...
Published: August, 2022
Abstract: Gypsophila paniculata, belonging to the Caryophyllaceae of the Caryophyllales, is one of the worldwide famous cut flowers. It is commonly used as d... Read more »
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Megaruptor
Patients with biallelic GGC repeat expansions in NOTCH2NLCexhibitin...
Published: August, 2022
Abstract: We report two patients with autosomal dominant neuronal intranuclear inclusion disease (NIID) harboring the biallelic GGC repeat expansion in NOTCH... Read more »
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Megaruptor
Histone demethylase KDM2A suppresses EGF-TSPAN8 pathway toinhibit b...
Published: August, 2022
Abstract: Metastasis is a major cause of breast cancer mortality and the current study found histone demethylase, KDM2A, expression to be negatively correlat... Read more »
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Antibody
Distinct silencer states generate epigenetic states of heterochroma...
Published: August, 2022
Abstract: Heterochromatic loci can exhibit different transcriptional states in genetically identical cells. A popular model posits that the inheritance of mo... Read more »
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Antibody
RAD51 protects human cells from transcription-replication conflicts.
Published: August, 2022
Abstract: Oncogene activation during tumorigenesis promotes DNA replication stress (RS), which subsequently drives the formation of cancer-associated chromos... Read more »
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iDeal ChIP-qPCR
The leaf beetle Chelymorpha alternans propagates a plant pathogen i...
Published: August, 2022
Abstract: Many insects rely on microbial protection in the early stages of their development. However, in contrast to symbiont-mediated defense of eggs and y... Read more »
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Megaruptor
bESCs from cloned embryos do not retain transcriptomic or epigeneti...
Published: August, 2022
Abstract: Embryonic stem cells (ESC) indefinitely maintain the pluripotent state of the blastocyst epiblast. Stem cells are invaluable for studying developme... Read more »
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Antibody
A haplotype resolved chromosomal level avocado genome allows analys...
Published: August, 2022
Abstract: Avocado (Persea americana) is a member of the magnoliids, an early branching lineage of angiosperms that has high value globally with the fruit bei... Read more »
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Megaruptor
Histone lysine demethylase inhibition reprograms prostate cancermet...
Published: August, 2022
Abstract: OBJECTIVE: Aberrant activity of androgen receptor (AR) is the primary cause underlying development and progression of prostate cancer (PCa) and cas... Read more »
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Antibody Bioruptor Plus
The Arabidopsis APOLO and human UPAT sequence-unrelated longnoncodi...
Published: August, 2022
Abstract: BACKGROUND: RNA-DNA hybrid (R-loop)-associated long noncoding RNAs (lncRNAs), including the Arabidopsis lncRNA AUXIN-REGULATED PROMOTER LOOP (APOLO... Read more »
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Bioruptor Antibody
Histone H3K36me2 and H3K36me3 form a chromatin platform essentialfo...
Published: August, 2022
Abstract: Establishment of the DNA methylation landscape of mammalian oocytes, mediated by the DNMT3A-DNMT3L complex, is crucial for reproduction and develop... Read more »
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Antibody
Epigenetic remodeling of downstream enhancer regions is linked tose...
Published: August, 2022
Abstract: Interleukin (IL)-38, encoded by the IL1F10 gene, is a member of the IL-1 family of cytokines. IL-38 is constitutively expressed in epithelia in hea... Read more »
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Antibody iDeal ChIP-qPCR
A SOX2-engineered epigenetic silencer factor represses the glioblas...
Published: August, 2022
Abstract: Current therapies remain unsatisfactory in preventing the recurrence of glioblastoma multiforme (GBM), which leads to poor patient survival. By rat... Read more »
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MagMeDIP kit CUT&Tag
mTORC1 is required for epigenetic silencing during β-cell functiona...
Published: August, 2022
Abstract: OBJECTIVE: The mechanistic target of rapamycin comple×1 (mTORC1) is a key molecule that links nutrients, hormones, and growth factors to cell... Read more »
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MagMeDIP kit
Prolonged FOS activity disrupts a global myogenic transcriptionalpr...
Published: August, 2022
Abstract: BACKGROUND: The AP-1 transcription factor, FBJ osteosarcoma oncogene (FOS), is induced in adult muscle satellite cells (SCs) within hours following... Read more »
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Bioruptor Antibody iDeal ChIP-qPCR
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesi...
Published: July, 2022
Abstract: People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and major depressive disorder (MDD) versus the general po... Read more »
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D-Plex small RNA-seq
Large-scale manipulation of promoter DNA methylation revealscontext...
Published: July, 2022
Abstract: BACKGROUND: Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome eng... Read more »
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Antibody
HOTAIR interacts with PRC2 complex regulating the regional preadipo...
Published: July, 2022
Abstract: Mechanisms governing regional human adipose tissue (AT) development remain undefined. Here, we show that the long non-coding RNA HOTAIR (HOX transc... Read more »
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Antibody
A novel, essential trans-splicing protein connects the nematode SL1...
Published: July, 2022
Abstract: Spliced leader trans-splicing is essential for gene expression in many eukaryotes. To elucidate the molecular mechanism of this process, we charact... Read more »
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D-Plex small RNA-seq
Interspecies effectors of a transgenerational memory of bacterial i...
Published: July, 2022
Abstract: The inheritance of memory is an adaptive trait. Microbes challenge the immunity of organisms and trigger behavioral adaptations that can be inherit... Read more »
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D-Plex small RNA-seq
X-linked myotubular myopathy is associated with epigenetic alterati...
Published: July, 2022
Abstract: X-linked myotubular myopathy (XLMTM) is a fatal neuromuscular disorder caused by loss of function mutations in MTM1. At present, there are no direc... Read more »
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Chromatin Shearing
The genome sequence of the hawthorn shieldbug, Acanthosomahaemorrho...
Published: July, 2022
Abstract: We present a genome assembly from an individual male Acanthosoma haemorrhoidale (hawthorn shieldbug; Arthropoda; Insecta; Hemiptera; Acanthosomatid... Read more »
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Megaruptor

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