Diagenode

Instruments

断片化技術

Exceptional shearing and sonication of biological samples for any field of study

Diagenode focuses on state-of-the-art preparation of high quality biological and chemical samples by developing the industry’s most advanced water bath sonicators and hydrodynamic devices. Our instruments are ideal for a number of applications in various fields of studies including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.

We offer three types of sonication/shearing devices to match your exact needs for your application:

  • The Picoruptor® uses a highly-controlled ultrasonic energy with ACT (Adaptive Cavitation Technology), a non-contact, parallel-processing and isothermal technology, to achieve optimal fragment sizes between 150bp-1kb which is ideal for chromatin shearing for chromatin immunoprecipitation (ChIP), genomic DNA shearing for next generation sequencing, and RNA shearing. In addition, the Picoruptor is perfect for cell and tissue disruption, protein processing for mass spectrometry, and much more. The Picoruptor is available in two models: the Picoruptor Plus, specifically designed for protein processing for mass spectrometry, high volume cell and tissue shearing, ChIP-qPCR, and other applications and the Picoruptor for ChIP-seq and NGS.
  • The One® is a unique desktop sonication device perfect for optimal small volume DNA shearing for Next-Generation-Sequencing in the 150bp - 1kb range.
  • The Megaruptor® is a hydrodynamic shearing instrument for DNA shearing between 3kb - 100kb and represents the best shearing device for the tightest distribution of long DNA fragments for applications such as long fragment sequencing.

Picoruptor®

Megaruptor®

One®

FEATURES

  • All in one shearing device
  • Advanced temperature control
  • > 4,000 peer reviewed publications
  • Optimal for long DNA fragment generation
  • Tight fragment length distribution
  • Hydropores eliminate clogging issue
  • Compact size
  • Small volume DNA and Chromatin shearing
  • Fully integrated system

APPLICATIONS

  • DNA, Chromatin and RNA shearing 150bp to 1kb
  • FFPE DNA extraction
  • RNA extraction
  • Cell and tissue disruption for protein extraction (for mass spectrometry or other applications)
  • Chemical applications (liposomes, emulsifications etc.)
  • Protein aggregation
  • DNA shearing 3kb to 100kb
  • DNA and Chromatin shearing 150bp to 1kb

優れた超音波処理とせん断が違いをもたらす研究分野

神経科学と神経疾患
腫瘍学
環境と毒物学
幹細胞の発達
植物と農業

注目のアプリケーション

  • ChIP-seqまたはChIP-qPCRのクロマチン断片化
  • 次世代シーケンシング:DNA、RNA、およびDNAメチル化
  • RNA抽出
  • FFPEからのDNA抽出
  • タンパク質抽出のための細胞および組織の破壊(質量分析またはその他のアプリケーション用)
  • タンパク質の可溶化
  • タンパク質凝集
  • リポソーム
  • 乳化

Diagenodeは、革新的な企業と提携し、Picoruptor テクノロジーを更に活用することで、ワークフローの最適化を実現します。

MS-BASED PROTEOMICS TECHNOLOGIES

Read our partnership application note for mass spectrometry applications

Visit partner website


DNA SHEARING AND SIZING FOR NGS

Read our partnership application note for using fragment analysis after sonication

Visit partner website


LONG FRAGMENT DNA SEQUENCING

Read our partnership application note for optimal long fragment sequencing

Visit partner website

Picoruptor®


  • some alt
    B01020001
    Bioruptor® Plus sonication device
  • Bioruptor-pico-next-gen-sequencing
    B01060010
    Picoruptor ® Sonicator

Megaruptor


  • Megaruptor 3
    B06010003
    Megaruptor® 3
  • Megaruptor 2
    B06010002
    Megaruptor® 2

One®


  • Bioruptor One
    B01070001
    Diagenode One sonication device

イベント

  • Molecular Biology Society of Japan
    Fukuoka
    Dec 3-Dec 6, 2019
  • ASH annual meeting
    Orlando, FL
    Dec 7-Dec 10, 2019
 すべてのイベントを見る

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