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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

PBRM1-deficient PBAF complexes target aberrant genomic loci to acti...
Published: April, 2023
Abstract: PBRM1 encodes an accessory subunit of the PBAF SWI/SNF chromatin remodeller, and the inactivation of PBRM1 is a frequent event in kidney cancer. Ho... Read more »
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Antibody
Integrated analysis from multicentre studies identities RNAmethylat...
Published: March, 2023
Abstract: Gastric cancer (GC) is the fourth leading cause of cancer death worldwide. Due to the lack of effective chemotherapy methods for advanced gastric c... Read more »
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Antibody
A genome sequence for Biomphalaria pfeifferi, the major vector snai...
Published: March, 2023
Abstract: BACKGROUND: Biomphalaria pfeifferi is the world's most widely distributed and commonly implicated vector snail species for the causative agent of h... Read more »
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The genome sequence of the Lime-speck Pug, Eupithecia centaureata (...
Published: March, 2023
Abstract: We present a genome assembly from an individual male Eupithecia centaureata (the Lime-speck Pug; Arthropoda; Insect; Lepidoptera; Geometridae). The... Read more »
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Analyzing genomic and epigenetic profiles in single cells by hybrid...
Published: March, 2023
Abstract: scGET-seq simultaneously profiles euchromatin and heterochromatin. scGET-seq exploits the concurrent action of transposase Tn5 and its hybrid form ... Read more »
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Tagmentase
The genome sequence of the Early Bumblebee, Bombus pratorum (Linnae...
Published: March, 2023
Abstract: We present a genome assembly from an individual female Bombus pratorum (the Early Bumblebee; Arthropoda; Insecta; Hymenoptera; Apidae). The genome ... Read more »
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The genome sequence of the Golden-tailed Leafwalker, Xylota sylvaru...
Published: March, 2023
Abstract: We present a genome assembly from an individual male Xylota sylvarum (the Golden-tailed Leafwalker; Arthropoda; Insecta; Diptera; Syrphidae). The g... Read more »
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DNA methylation changes from primary cultures through senescence-by...
Published: March, 2023
Abstract: Current chemical testing strategies are limited in their ability to detect non-genotoxic carcinogens (NGTxC). Epigenetic anomalies develop during c... Read more »
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Premium RRBS Kit
A highly-contiguous and annotated genome assembly of the Lesser Pra...
Published: March, 2023
Abstract: The Lesser Prairie-Chicken (Tympanuchus pallidicinctus; LEPC) is an iconic North American prairie grouse, renowned for ornate and spectacular breed... Read more »
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Chromatin profiling identifies transcriptional readthrough as a con...
Published: March, 2023
Abstract: The piRNA pathway in mosquitoes differs substantially from other model organisms, with an expanded PIWI gene family and functions in antiviral defe... Read more »
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Antibody
The genome sequence of the Ruby Tiger, Phragmatobia fuliginosa (Lin...
Published: March, 2023
Abstract: We present a genome assembly from an individual male Phragmatobia fuliginosa (the Ruby Tiger; Arthropoda; Insecta; Lepidoptera; Erebidae). The geno... Read more »
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Epigenetic dosage identifies two major and functionally distinct be...
Published: March, 2023
Abstract: The mechanisms that specify and stabilize cell subtypes remain poorly understood. Here, we identify two major subtypes of pancreatic β ... Read more »
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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
The genome sequence of the White-shouldered Marble, Apotomis turbid...
Published: March, 2023
Abstract: We present a genome assembly from an individual male Apotomis turbidana (the White-shouldered Marble; Arthropoda; Insecta; Lepidoptera; Tortricidae... Read more »
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Altered DNA methylation and gene expression predict disease severit...
Published: March, 2023
Abstract: Aicardi-Goutières Syndrome (AGS) is a rare neuro-inflammatory disease characterized by increased expression of interferon-stimulated genes (... Read more »
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Infinium Human MethylationEPIC Array Service
Comprehensive molecular phenotyping of -deficient gastric cancer re...
Published: March, 2023
Abstract: OBJECTIVE: Gastric cancer (GC) is a leading cause of cancer mortality, with being the second most frequently mutated driver gene in GC. We sought t... Read more »
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Antibody
Single substitution in H3.3G34 alters DNMT3A recruitment to causepr...
Published: March, 2023
Abstract: Germline histone H3.3 amino acid substitutions, including H3.3G34R/V, cause severe neurodevelopmental syndromes. To understand how these mutations ... Read more »
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Antibody
Synthetic maize centromeres transmit chromosomes across generations.
Published: March, 2023
Abstract: Centromeres are long, often repetitive regions of genomes that bind kinetochore proteins and ensure normal chromosome segregation. Engineering cent... Read more »
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ChIP-qPCR
The RNA m5C Methylase NSUN2 Modulates Corneal EpithelialWound Healing.
Published: March, 2023
Abstract: PURPOSE: The emerging epitranscriptomics offers insights into the physiopathological roles of various RNA modifications. The RNA methylase NOP2/Sun... Read more »
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Antibody
Immunoregulatory Biomarkers of the Remission Phase in Type 1 Diabet...
Published: February, 2023
Abstract: The partial remission (PR) phase of type 1 diabetes (T1D) is an underexplored period characterized by endogenous insulin production and downmodulat... Read more »
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D-Plex small RNA-seq
Pre-diagnosis plasma cell-free DNA methylome profiling up to seveny...
Published: February, 2023
Abstract: Profiling of cell-free DNA (cfDNA) has been well demonstrated to be a potential non-invasive screening tool for early cancer detection. However, li... Read more »
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MagMeDIP kit IPure kit
Cell-free multi-omics analysis reveals tumor status-informativesign...
Published: February, 2023
Abstract: During cancer development, host’s tumorigenesis and immune signals are released to and informed by circulating molecules, like cell-free DNA ... Read more »
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MagMeDIP kit
Low affinity CTCF binding drives transcriptional regulation whereas...
Published: February, 2023
Abstract: CTCF is a DNA-binding protein which plays critical roles in chromatin structure organization and transcriptional regulation; however, little is kno... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Draft genome assemblies of the avian louse Brueelia nebulosa and it...
Published: February, 2023
Abstract: Sequencing high molecular weight (HMW) DNA with long-read and linked-read technologies has promoted a major increase in more complete genome sequen... Read more »
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Targeting high glucose-induced epigenetic modifications at cardiac ...
Published: February, 2023
Abstract: BACKGROUND: Sodium-glucose co-transporters (SGLT) inhibitors (SGLT2i) showed many beneficial effects at the cardiovascular level. Several mechanism... Read more »
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Antibody
Myelodysplastic Syndrome associated TET2 mutations affect NK cellfu...
Published: February, 2023
Abstract: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders, representing high risk of progression to acute myeloid leukaemia, and frequentl... Read more »
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Antibody Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Species-specific regulation of XIST by the JPX/FTX orthologs.
Published: February, 2023
Abstract: X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main tr... Read more »
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Antibody
Retrospective analysis of enhancer activity and transcriptome history.
Published: February, 2023
Abstract: Cell state changes in development and disease are controlled by gene regulatory networks, the dynamics of which are difficult to track in real time... Read more »
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CUT&Tag
Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42...
Published: February, 2023
Abstract: Reduced insulin-like growth factor 2 (IGF2) levels in Alzheimer's disease (AD) may be the mechanism relating age-related metabolic disorders to dem... Read more »
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Antibody
The genome sequence of the Grey Ermine, Yponomeuta sedella (Treitsc...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Yponomeuta sedella (the Grey Ermine; Arthropoda; Insecta; Lepidoptera; Yponomeutidae). The gen... Read more »
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The genome sequence of the Mouse Moth, Amphipyra tragopoginis (Cler...
Published: February, 2023
Abstract: We present a genome assembly from an individual male Amphipyra tragopoginis (the Mouse Moth; Arthropoda; Insecta; Lepidoptera; Noctuidae). The geno... Read more »
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イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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