Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

NanoTag - an IgG-free method for mapping DNA-protein interactions
Published: July, 2024

Abstract: Genome-wide profiling of DNA-protein interactions in cells can provide important information about mechanisms of gene regulation. Most current meth... Read more »

Tags
CUT&Tag
Epigenetic alterations affecting hematopoietic regulatory networks ...
Published: July, 2024

Abstract: Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile t... Read more »

Tags
Antibody Microplex Library Preparation kit
The landscape of RNA-chromatin interaction reveals small non-coding...
Published: June, 2024

Abstract: RNA constitutes a large fraction of chromatin. Spatial distribution and functional relevance of most of RNA-chromatin interactions remain unknown. ... Read more »

Tags
Bioruptor Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Epigenomic signatures of sarcomatoid differentiation to guide the t...
Published: June, 2024

Abstract: Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibi... Read more »

Tags
MagMeDIP kit Antibody IPure kit
CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
Published: June, 2024

Abstract: The SWI/SNF (or BAF) complex is an essential chromatin remodeler that regulates DNA accessibility at developmental genes and enhancers. SWI/SNF sub... Read more »

Tags
Tagmentase
KRAS promotes GLI2-dependent transcription during pancreatic carcin...
Published: June, 2024

Abstract: Aberrant activation of GLI transcription factors has been implicated in the pathogenesis of different tumor types including pancreatic ductal adeno... Read more »

Tags
Antibody
Detecting small cell transformation in patients with advanced EGFR ...
Published: June, 2024

Abstract: Purpose: Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-drive... Read more »

Tags
MagMeDIP kit IPure kit
Single-cell epigenomic reconstruction of developmental trajectories...
Published: June, 2024

Abstract: Cell fate progression of pluripotent progenitors is strictly regulated, resulting in high human cell diversity. Epigenetic modifications also orche... Read more »

Tags
Bioruptor Antibody
Prostate cancer detection through unbiased capture of methylated ce...
Published: June, 2024

Abstract: Prostate cancer screening using prostate-specific antigen (PSA) has been shown to reduce mortality but with substantial overdiagnosis, leading to u... Read more »

Tags
MagMeDIP kit IPure kit
The ETO2 transcriptional cofactor maintains acute leukemia by drivi...
Published: June, 2024

Abstract: Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating tran... Read more »

Tags
IPure kit
Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024

Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »

Tags
Antibody
Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024

Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »

Tags
Antibody
Patho-transcriptomic analysis of invasive mucinous adenocarcinoma o...
Published: June, 2024

Abstract: Background Invasive mucinous adenocarcinoma (IMA) comprises ∼5% of lung adenocarcinoma. There is no effective therapy for IMA when surgi... Read more »

Tags
ATAC-seq
Brassica rapa CURLY LEAF is a major H3K27 methyltransferase regulat...
Published: June, 2024

Abstract: Main conclusion In Brassica rapa, the epigenetic modifier BraA.CLF orchestrates flowering by modulating H3K27me3 levels at the floral integra... Read more »

Tags
Antibody
Clock-dependent chromatin accessibility rhythms regulate circadian ...
Published: May, 2024

Abstract: Chromatin organization plays a crucial role in gene regulation by controlling the accessibility of DNA to transcription machinery. While significan... Read more »

Tags
Tagmentase
Disease related changes in ATAC-seq of iPSC-derived motor neuron li...
Published: May, 2024

Abstract: Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only a small fraction of cases expla... Read more »

Tags
ATAC-seq
Transient loss of Polycomb components induces an epigenetic cancer ...
Published: April, 2024

Abstract: Although cancer initiation and progression are generally associated with the accumulation of somatic mutations1,2, substantial epigenomic alteratio... Read more »

Tags
ATAC-seq
PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic...
Published: April, 2024

Abstract: PBK/TOPK is a mitotic kinase implicated in haematological and non-haematological cancers. Here we show that the key haemopoietic regulators Ikaros ... Read more »

Tags
Tagmentase
Widespread impact of nucleosome remodelers on transcription at cis-...
Published: April, 2024

Abstract: Nucleosome remodeling complexes and other regulatory factors work in concert to build a chromatin environment that directs the expression of a dist... Read more »

Tags
Tagmentase
Positive and negative feedback regulation of the TGF-β1 explains tw...
Published: April, 2024

Abstract: During aging, skin homeostasis is essential for maintaining appearance, as well as biological defense of the human body. In this study, we identi... Read more »

Tags
iDeal ChIP-seq Kit for Histones
Cis-regulatory interfaces reveal the molecular mechanisms underlyin...
Published: April, 2024

Abstract: Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulator... Read more »

Tags
CRISPR
Systematic mapping of TF-mediated cell fate changes by a pooled ind...
Published: April, 2024

Abstract: Transcriptional regulation controls cellular functions through interactions between transcription factors (TFs) and their chromosomal targets. Howe... Read more »

Tags
ATAC-seq
Differential DNA methylation in iPSC-derived dopaminergic neurons: ...
Published: April, 2024

Abstract: Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) feat... Read more »

Tags
Premium RRBS Kit
Epigenetics and suicide: investigating altered H3K14ac unveiled dif...
Published: March, 2024

Abstract: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to ch... Read more »

Tags
ChIPmentation
TET2 Deficiency Increases the Competitive Advantage of Hematopoieti...
Published: March, 2024

Abstract: Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, th... Read more »

Tags
Chromatin Shearing
Integrative network analysis of differentially methylated regions t...
Published: March, 2024

Abstract: Integrative network analysis (INA) is important for identifying gene modules or epigenetically regulated molecular pathways in diseases. This study... Read more »

Tags
Infinium Human MethylationEPIC Array Service
High-throughput sequencing of insect specimens with sub-optimal DNA...
Published: March, 2024

Abstract: Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may ... Read more »

Tags
Tagmentase
Technical considerations for cost-effective transposon directed ins...
Published: March, 2024

Abstract: Transposon directed insertion-site sequencing (TraDIS), a variant of transposon insertion sequencing commonly known as Tn-Seq, is a high-throughput... Read more »

Tags
Tagmentase
MED1 IDR acetylation reorganizes the transcription preinitiation co...
Published: March, 2024

Abstract: With our current appreciation of the complexity of eukaryotic transcription, whose dysregulation drives diseases including cancer, it is becoming a... Read more »

Tags
Tagmentase
Protocol to isolate nuclei from Chlamydomonas reinhardtii for ATAC ...
Published: March, 2024

Abstract: Highlights Optimized isolation of nuclei from the green model alga Chlamydomonas reinhardtii Tag-free isolation from both cell-w... Read more »

Tags
ATAC-seq

イベント

  • American Association of Cancer Research (AACR)
    Chicago (IL), USA
    Apr 25-Apr 30, 2025
  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
 すべてのイベントを見る

 


       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy