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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Chemokine switch regulated by TGF-β1 in cancer-associated fibroblas...
Published: January, 2022

Abstract: Combining immunogenic cell death-inducing chemotherapies and PD-1 blockade can generate remarkable tumor responses. It is now well established that... Read more »

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Antibody IP-Star Compact
Development and inter-laboratory validation of the VISAGE enhanced ...
Published: January, 2022

Abstract: The analysis of DNA methylation has become an established method for chronological age estimation. This has triggered interest in the forensic comm... Read more »

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Premium Bisulfite Kit
27-Hydroxycholesterol, The Estrogen Receptor Modulator, AltersDNA M...
Published: January, 2022

Abstract: 27-hydroxycholesterol (27-HC) is the first known endogenous selective estrogen receptor modulator (SERM), and its elevation from normal levels is c... Read more »

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Antibody
Loss of KMT2C reprograms the epigenomic landscape in hPSCsresulting...
Published: January, 2022

Abstract: Germline or somatic variation in the family of KMT2 lysine methyltransferases have been associated with a variety of congenital disorders and cance... Read more »

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Antibody
Single cell quantification of ribosome occupancy in early mouse dev...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq
Single cell quantification of ribosome occupancy in early mousedeve...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq
Androgen receptor and MYC equilibration centralizes on developmenta...
Published: December, 2021

Abstract: Androgen receptor (AR) in prostate cancer (PCa) can drive transcriptional repression of multiple genes including MYC, and supraphysiological androg... Read more »

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Antibody
A predominant enhancer co-amplified with the oncogene is necessary...
Published: December, 2021

Abstract: Amplification and overexpression of the SOX2 oncogene represent a hallmark of squamous cancers originating from diverse tissue types. Here, we find... Read more »

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CRISPR
The long noncoding RNA H19 regulates tumor plasticity inneuroendocr...
Published: December, 2021

Abstract: Neuroendocrine (NE) prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer (PCa) arising either de novo or from transdi... Read more »

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Antibody
Sevoflurane induces inflammation in primary hippocampal neurons byr...
Published: December, 2021

Abstract: Postoperative cognitive dysfunction (POCD) is a normal condition that develops after surgery with anesthesia, leading to deterioration of cognitive... Read more »

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iDeal ChIP-qPCR
Epigenetic Silencing of OR and TAS2R Genes Expression inHuman Orbit...
Published: December, 2021

Abstract: Modulation of brain olfactory (OR) and taste receptors (TASR) expression was recently reported in neurological diseases. We explored the possible e... Read more »

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Antibody
Gene bookmarking by the heat shock transcription factor programs th...
Published: December, 2021

Abstract: Maternal stress can have long-lasting epigenetic effects on offspring. To examine how epigenetic changes are triggered by stress, we examined the e... Read more »

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Antibody
Examining age-dependent DNA methylation patterns and gene expressio...
Published: December, 2021

Abstract: DNA methylation is a well-characterized epigenetic modification involved in numerous molecular and cellular functions. Methylation patterns have al... Read more »

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MagMeDIP kit
Cancer Detection and Classification by CpG Island Hypermethylation ...
Published: November, 2021

Abstract: Cell-free DNA (cfDNA) methylation has emerged as a promising biomarker for early cancer detection, tumor type classification, and treatment respons... Read more »

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MethylCap kit
Epromoters function as a hub to recruit key transcription factorsre...
Published: November, 2021

Abstract: Gene expression is controlled by the involvement of gene-proximal (promoters) and distal (enhancers) regulatory elements. Our previous results demo... Read more »

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Antibody Microplex Library Preparation kit
Soluble guanylate cyclase signalling mediates etoposide resistance ...
Published: November, 2021

Abstract: Small cell lung cancer (SCLC) has a 5-year survival rate of \<7\%. Rapid emergence of acquired resistance to standard platinum-etoposide chemoth... Read more »

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ChIP Cross-link Gold
Decreased PRC2 activity supports the survival of basal-like breastc...
Published: November, 2021

Abstract: Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development... Read more »

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Microplex Library Preparation kit
Comparing the epigenetic landscape in myonuclei purified with a PCM...
Published: November, 2021

Abstract: Muscle cells have different phenotypes adapted to different usage, and can be grossly divided into fast/glycolytic and slow/oxidative types. While ... Read more »

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Antibody
Reference genome assembly of the big berry Manzanita (Arctostaphylo...
Published: November, 2021

Abstract: Arctostaphylos (Ericaceae) species, commonly known as manzanitas, are an invaluable fire-adapted chaparral clade in the California Floristic Provin... Read more »

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Megaruptor
Conditional depletion of transcriptional kinases Ctk1 and Bur1 ande...
Published: November, 2021

Abstract: From yeast to humans, pre-mRNA splicing occurs mainly co-transcriptionally, with splicing and transcription functionally coupled such that they inf... Read more »

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Antibody
ATRX regulates glial identity and the tumor microenvironment inIDH-...
Published: November, 2021

Abstract: Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of... Read more »

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Antibody CUT&Tag
Ago1 controls myogenic differentiation by regulating eRNA-mediatedC...
Published: November, 2021

Abstract: The role of chromatin-associated RNAi components in the nucleus of mammalian cells and in particular in the context of developmental programs remai... Read more »

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Microplex Library Preparation kit
Characteristics of Immediate-Early 2 (IE2) and UL84 Proteins in UL8...
Published: October, 2021

Abstract: Human cytomegalovirus (HCMV) immediate-early 2 (IE2) protein is the major transactivator for viral gene expression and is required for lytic replic... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
The ETS transcription factor ERF controls the exit from the naïve p...
Published: October, 2021

Abstract: The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this ... Read more »

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Premium RRBS Kit DNA Methylation
Adaptive Convergence of Methylomes Reveals Epigenetic Driversand Bo...
Published: October, 2021

Abstract: Ependymoma (EPN) is the third most common brain tumor in children and frequently recurs. Here, we report an integrated longitudinal analysis of epi... Read more »

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Premium RRBS Kit
Short-Chain Fatty Acids Calibrate RARα Activity RegulatingFood Sens...
Published: October, 2021

Abstract: Gut-microbiota dysbiosis links to allergic diseases. The mechanism of the exacerbation of food allergy caused by gut-microbiota dysbiosis remains u... Read more »

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Antibody
Autocrine Vitamin D-signaling switches off pro-inflammatory program...
Published: October, 2021

Abstract: The molecular mechanisms governing orderly shutdown and retraction of CD4+ T helper (Th)1 responses remain poorly understood. Here, we show that co... Read more »

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True MicroChIP kit CUT&Tag
Rhesus macaques self-curing from a schistosome infection can displa...
Published: October, 2021

Abstract: The rhesus macaque provides a unique model of acquired immunity against schistosomes, which afflict \>200 million people worldwide. By monitorin... Read more »

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Antibody IP-Star Compact ChIPmentation
Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASRcomp...
Published: October, 2021

Abstract: Rett syndrome (RTT) is a severe neurological disorder and a leading cause of intellectual disability in young females. RTT is mainly caused by muta... Read more »

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Antibody
SETD2-mediated epigenetic regulation of noncanonical Wnt5A duringos...
Published: October, 2021

Abstract: Graphic abstract To define the role of SETD2 in the WNT5a signaling in the context of osteoclastogenesis, we exploited two different models: in vit... Read more »

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Antibody

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