Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pl...
Published: January, 2024

Abstract: Human naïve pluripotent stem cells (nPSCs) can differentiate into extra-embryonic trophectoderm (TE), a critical step in the generation of the... Read more »

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ATAC-seq
Diagnostic Algorithm to Subclassify Atypical Spitzoid Tumors in Low...
Published: December, 2023

Abstract: Current diagnostic algorithms are insufficient for the optimal clinical and therapeutic management of cutaneous spitzoid tumors, particularly atypi... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
The ncBAF complex regulates transcription in AML through H3K27ac se...
Published: December, 2023

Abstract: The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemog... Read more »

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Tagmentase
In vitro production of cat-restricted Toxoplasma pre-sexual stages
Published: December, 2023

Abstract: Sexual reproduction of Toxoplasma gondii, confined to the felid gut, remains largely uncharted owing to ethical concerns regarding the use of ... Read more »

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Antibody IPure kit iDeal ChIP-seq Kit for Transcription Factors ATAC-seq
Challenges in characterization of transcriptomes of extracellular v...
Published: December, 2023

Abstract: Since its original discovery over a decade ago, extracellular RNA (exRNA) has been found in all biological fluids. Furthermore, extracellular micro... Read more »

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D-Plex small RNA-seq
SMARCB1 loss activates patient-specific distal oncogenic enhancers ...
Published: December, 2023

Abstract: Malignant rhabdoid tumor (MRT) is a highly malignant and often lethal childhood cancer. MRTs are genetically defined by bi-allelic inactivating mut... Read more »

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Microplex Library Preparation kit
The genetic landscape of origins of replication in P. falciparum
Published: December, 2023

Abstract: Various origin mapping approaches have enabled genome-wide identification of origins of replication (ORI) in model organisms, but only a few studie... Read more »

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Microplex Library Preparation kit
DAXX promotes centromeric stability independently of ATRX by preven...
Published: December, 2023

Abstract: Maintaining chromatin integrity at the repetitive non-coding DNA sequences underlying centromeres is crucial to prevent replicative stress, DNA bre... Read more »

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iDeal ChIP-qPCR
An enriched maternal environment and stereotypies of sows different...
Published: December, 2023

Abstract: Epigenetic mechanisms are important modulators of neurodevelopmental outcomes in the offspring of animals challenged during pregnancy. Pregnant sow... Read more »

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Antibody
Association of DNA methylation signatures with premature ageing and...
Published: December, 2023

Abstract: Patients with end-stage kidney disease (ESKD) display features of premature aging. There is strong evidence that changes in DNA methylation (DNAm) ... Read more »

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Infinium Human MethylationEPIC Array Service
SUMO protease FUG1, histone reader AL3 and the PRC1 Complex areinte...
Published: December, 2023

Abstract: Epigenetic gene silencing induced by expanded repeats can cause diverse phenotypes ranging from severe growth defects in plants to genetic diseases... Read more »

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Antibody
KDM6B drives epigenetic reprogramming associated with lymphoid stro...
Published: November, 2023

Abstract: Mature lymphoid stromal cells (LSCs) are key organizers of immune responses within secondary lymphoid organs. Similarly, inflammation-driven tertia... Read more »

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Antibody
LEO1 Is Required for Efficient Entry into Quiescence, Control of H3...
Published: November, 2023

Abstract: (1) Background: The LEO1 (Left open reading frame 1) protein is a conserved subunit of the PAF1C complex (RNA polymerase II-associated factor 1 com... Read more »

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iDeal ChIP-seq Kit for Histones
Guidelines for Performing Ribosome Profiling in Plants Including St...
Published: November, 2023

Abstract: Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Across differen... Read more »

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D-Plex small RNA-seq
Integrated multiplexed assays of variant effect reveal cis-regulato...
Published: November, 2023

Abstract: Multiplexed assays of variant effect are powerful methods to profile the consequences of rare variants on gene expression and organismal fitness. Y... Read more »

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D-Plex small RNA-seq
Vaginal microbes alter epithelial transcriptomic and epigenomic mod...
Published: November, 2023

Abstract: The cervicovaginal microbiome is highly associated with women's health with microbial communities dominated by Lactobacillus spp. being c... Read more »

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ATAC-seq
H3K9 methylation patterns during somatic embryogenic competenceexpr...
Published: November, 2023

Abstract: The capacity to regenerate is intrinsic to plants and is the basis of natural asexual propagation and artificial cloning. Despite there are differe... Read more »

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Antibody
The Ribosome Assembly Factor Reh1 is Released from the Polypeptide ...
Published: October, 2023

Abstract: Assembly of functional ribosomal subunits and successfully delivering them to the translating pool is a prerequisite for protein synthesis and cell... Read more »

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D-Plex small RNA-seq
Inflammatory stress-mediated chromatin changes underlie dysfunction...
Published: October, 2023

Abstract: Inflammatory stresses underlie endothelial dysfunction and contribute to the development of chronic cardiovascular disorders such as atherosclerosi... Read more »

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Chromatin Profiling (ChIP-seq) Services ATAC-seq
A transgenic mice model of retinopathy of cblG-type inherited disor...
Published: October, 2023

Abstract: BACKGROUND: MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolis... Read more »

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G-quadruplexes of KSHV oriLyt play important roles in promoting lyt...
Published: October, 2023

Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes distinct origins of DNA replication (origin of replications) during the latent and lytic ph... Read more »

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ARID1A governs the silencing of sex-linked transcription during mal...
Published: September, 2023

Abstract: We present evidence implicating the BAF (BRG1/BRM Associated Factor) chromatin remodeler in meiotic sex chromosome inactivation (MSCI). By immunofl... Read more »

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Tagmentase
Knockout of the longevity gene Klotho perturbs aging- and Alzheimer...
Published: September, 2023

Abstract: Overexpression of the longevity gene Klotho prolongs, while its knockout shortens lifespan and impairs cognition via altered fibroblast growth fact... Read more »

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D-Plex small RNA-seq
A Type II-B Cas9 nuclease with minimized off-targets and reduced ch...
Published: September, 2023

Abstract: Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as genome editors, but their promiscuous nuclease activity often ... Read more »

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Tagmentase
Combined Analysis of mRNA Expression and Open Chromatin in Microglia
Published: August, 2023

Abstract: The advance of single-cell RNA-sequencing technologies in the past years has enabled unprecedented insights into the complexity and heterogeneity o... Read more »

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Tagmentase
Volumetric imaging of an intact organism by a distributed molecular...
Published: August, 2023

Abstract: Lymphatic, nervous, and tumoral tissues, among others, exhibit physiology that emerges from three-dimensional interactions between genetically uniq... Read more »

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Tagmentase
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »

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Newly added
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »
Cerebrospinal fluid methylome-based liquid biopsies for accuratemal...
Published: August, 2023

Abstract: BACKGROUND: Resolving the differential diagnosis between brain metastases (BM), glioblastomas (GBM), and central nervous system lymphomas (CNSL) is... Read more »

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MagMeDIP kit IPure kit
Nuclear proinflammatory cytokine S100A9 enhances expression of huma...
Published: August, 2023

Abstract: Transcription of the human papillomavirus (HPV) oncogenes, and , is regulated by the long control region (LCR) of the viral genome. Although vario... Read more »

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