Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Identification of Laportea bulbifera using the Complete Chloroplast...
Published: July, 2022

Abstract: Laportea bulbifera, a Miao medicine grown in karst areas, has exerts a unique curative effect on skin itching in the elderly, with an annual sales ... Read more »

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Megaruptor
The genome sequence of the dun-bar pinion, Cosmia trapezina(Linnaeu...
Published: July, 2022

Abstract: We present a genome assembly from an individual male Cosmia trapezina (dun-bar pinion; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome seq... Read more »

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Megaruptor
Genome-wide DNA hypermethylation opposes healing in chronic woundpa...
Published: July, 2022

Abstract: An extreme chronic wound tissue microenvironment causes epigenetic gene silencing. Unbiased whole-genome methylome was studied in the wound-edge (W... Read more »

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MethylCap
Oxford Nanopore R10.4 long-read sequencing enables the generation o...
Published: July, 2022

Abstract: Long-read Oxford Nanopore sequencing has democratized microbial genome sequencing and enables the recovery of highly contiguous microbial genomes f... Read more »

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Megaruptor
Embryonic heat conditioning in chicks induces transgenerationalheat...
Published: July, 2022

Abstract: The question of whether behavioral traits are heritable is under debate. An obstacle in demonstrating transgenerational inheritance in mammals orig... Read more »

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Antibody
Androgen-Induced MIG6 Regulates Phosphorylation ofRetinoblastoma Pr...
Published: July, 2022

Abstract: The bipolar androgen therapy (BAT) includes the treatment of prostate cancer (PCa) patients with supraphysiological androgen level (SAL). Interesti... Read more »

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iDeal ChIP-seq Kit for Transcription Factors ChIP Cross-link Gold
Epiblast inducers capture mouse trophectoderm stem cells in vitro a...
Published: July, 2022

Abstract: The embryo instructs the allocation of cell states to spatially regulate functions. In the blastocyst, patterning of trophoblast (TR) cells ensures... Read more »

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Antibody
Nox4 promotes endothelial differentiation through chromatin remodel...
Published: July, 2022

Abstract: RATIONALE: Nox4 is a constitutively active NADPH oxidase that constantly produces low levels of HO. Thereby, Nox4 contributes to cell homeostasis a... Read more »

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Antibody
Complete Genome Sequences of Multidrug-Resistant Campylobactercoli ...
Published: July, 2022

Abstract: Campylobacter coli is an important foodborne pathogen that can cause inflammation of the intestine and diarrhea in humans. The complete genomes, in... Read more »

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Megaruptor
High-Quality Genome Assembly of Nannochloris desiccata 2437 andIts ...
Published: July, 2022

Abstract: High-quality genome sequences were generated for the nonaxenic marine microalga Nannochloris desiccata UTEX 2437 and eight of its associated enviro... Read more »

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Megaruptor
Diverse Monogenic Subforms of Human Spermatogenic Failure
Published: July, 2022

Abstract: Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically incurable with current medicine. Due to the biological ... Read more »

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D-Plex small RNA-seq
Dual role of histone variant H3.3B in spermatogenesis: positiveregu...
Published: July, 2022

Abstract: The histone variant H3.3 is encoded by two distinct genes, H3f3a and H3f3b, exhibiting identical amino-acid sequence. H3.3 is required for spermato... Read more »

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Microplex Library Preparation kit
Systematic comparison of CRISPR-based transcriptional activatorsunc...
Published: July, 2022

Abstract: Nuclease-inactivated CRISPR/Cas-based (dCas-based) systems have emerged as powerful technologies to synthetically reshape the human epigenome and g... Read more »

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Antibody CRISPR
Equilibrated evolution of the mixed auto-/allopolyploid haplotype-r...
Published: July, 2022

Abstract: Understanding genome evolution of polyploids requires dissection of their often highly similar subgenomes and haplotypes. Polyploid animal genome a... Read more »

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Newly added
PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor,...
Published: July, 2022

Abstract: The synthetic lethal association between BRCA deficiency and poly (ADP-ribose) polymerase (PARP) inhibition supports PARP inhibitor (PARPi) clinica... Read more »

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iDeal ChIP-qPCR
Co-inhibition of ATM and ROCK synergistically improves cellprolifer...
Published: July, 2022

Abstract: The multifaceted nature of senescent cell cycle arrest necessitates the targeting of multiple factors arresting or promoting the cell cycle. We rep... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Spatially resolved epigenome-transcriptome co-profiling of mammalia...
Published: June, 2022

Abstract: Emerging spatial technologies including spatial transcriptomics and spatial epigenomics are becoming powerful tools for profiling cellular states i... Read more »

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Tagmentase CUT&Tag
Epigenomic analysis reveals a dynamic and context-specific macropha...
Published: June, 2022

Abstract: BACKGROUND: Chromatin states and enhancers associate gene expression, cell identity and disease. Here, we systematically delineate the acute innate... Read more »

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Antibody
Derailed peripheral circadian genes in polycystic ovary syndrome pa...
Published: June, 2022

Abstract: STUDY QUESTION: Do circadian genes exhibit an altered profile in peripheral blood mononuclear cells (PBMCs) of polycystic ovary syndrome (PCOS) pat... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Nuclear receptor RORγ inverse agonists/antagonists display tissue- ...
Published: June, 2022

Abstract: The nuclear receptor RORγ is a major driver of autoimmune diseases and certain types of cancer due to its aberrant function in T helper 17 (T... Read more »

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Antibody
Ultrasensitive Ribo-seq reveals translational landscapes duringmamm...
Published: June, 2022

Abstract: In mammals, translational control plays critical roles during oocyte-to-embryo transition (OET) when transcription ceases. However, the underlying ... Read more »

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D-Plex small RNA-seq
Detection of ovarian cancer using plasma cell-free DNA methylomes.
Published: June, 2022

Abstract: BACKGROUND: Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovari... Read more »

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MagMeDIP kit
HISTONE DEACETYLASE 15 and MOS4-Associated Complex subunits3A/3B co...
Published: June, 2022

Abstract: Histone deacetylases (HDAs) play an important role in transcriptional regulation of multiple biological processes. In this study, we investigated t... Read more »

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Antibody
TBX2 acts as a potent transcriptional silencer of tumour suppressor...
Published: June, 2022

Abstract: Chromosome 17q23 amplification occurs in 20\% of primary breast tumours and is associated with poor outcome. The TBX2 gene is located on 17q23 and ... Read more »

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Microplex Library Preparation kit
Analysis of estrogen-regulated enhancer RNAs identifies a functiona...
Published: June, 2022

Abstract: To better understand the functions of non-coding enhancer RNAs (eRNAs), we annotated the estrogen-regulated eRNA transcriptome in estrogen receptor... Read more »

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CRISPR
A genome-wide screen reveals new regulators of the 2-cell-like cell...
Published: June, 2022

Abstract: In mammals, only the zygote and blastomeres of the early embryo are fully totipotent. This totipotency is mirrored in vitro by mouse "2-cell-like c... Read more »

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MagMeDIP kit IP-Star Compact
Long-read Oxford nanopore sequencing reveals a de novo case of comp...
Published: June, 2022

Abstract: BACKGROUND: Complex chromosomal rearrangements (CCRs) are associated with high reproductive risk, infertility, abnormalities in offspring, and recu... Read more »

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Megaruptor
NSUN2-mediated RNA mC modification modulates uveal melanoma cellpro...
Published: June, 2022

Abstract: RNA 5-methylcytosine (mC) is a widespread post-transcriptional modification involved in diverse biological processes through controlling RNA metabo... Read more »

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Antibody
Accumulation of endosymbiont genomes in an insect autosome followed...
Published: May, 2022

Abstract: Eukaryotic genomes can acquire bacterial DNA via lateral gene transfer (LGT). A prominent source of LGT is Wolbachia, a widespread endosymbiont of ... Read more »

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Megaruptor
DNA Hypermethylation and a Specific Methylation Spectrum on theX Ch...
Published: May, 2022

Abstract: The molecular genetic mechanism of Turner syndrome (TS) still leaves much to be discovered. Methods: TS (45X0) patients and age-matched controls (4... Read more »

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Megaruptor

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