Publications,References

Interplay between coding and non-coding regulation drives the Arabi...
Published: February, 2024

Abstract: Translation of seed stored mRNAs is essential to trigger germination. However, when RNAPII re-engages RNA synthesis during the seed-to-seedling tra... Read more »

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ATAC-seq

Cellular reprogramming in vivo initiated by SOX4 pioneer factor act...
Published: February, 2024

Abstract: Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is ... Read more »

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Tagmentase

MYB/LINC00092 regulatory axis promotes the progression of papillary...
Published: February, 2024

Abstract: Introduction:Thyroid carcinoma is the most frequent malignancy in different endocrine-related tumours. In this study, we demonstrated a long non-co... Read more »

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iDeal ChIP-qPCR

Plasticity-induced repression of Irf6 underlies acquired resistance...
Published: February, 2024

Abstract: Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic d... Read more »

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Tagmentase

Multiomics uncovers the epigenomic and transcriptomic response to v...
Published: February, 2024

Abstract: Uncovering the epigenomic regulation of immune responses is essential for a comprehensive understanding of host defence mechanisms but remains poor... Read more »

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Microplex Library Preparation kit ChIPmentation

Neurofibromin 1 controls metabolic balance and Notch-dependent quie...
Published: February, 2024

Abstract: Patients affected by neurofibromatosis type 1 (NF1) frequently show muscle weakness with unknown etiology. Here we show that, in mice, Neurofibromi... Read more »

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MagMeDIP kit

Inhibition of Aurora kinase induces endogenous retroelements to ind...
Published: February, 2024

Abstract: Type I interferon signaling is a crucial component of anti-viral immunity that has been linked to promoting the efficacy of some chemotherapeutic d... Read more »

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Infinium Human MethylationEPIC Array Service

The transcriptional regulatory network modulating human trophoblast...
Published: February, 2024

Abstract: During human pregnancy, extravillous trophoblasts play crucial roles in placental invasion into the maternal decidua and spiral artery remodeling. ... Read more »

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ATAC-seq

Cancer Cell Biomechanical Properties Accompany Tspan8-Dependent Cut...
Published: February, 2024

Abstract: The intrinsic biomechanical properties of cancer cells remain poorly understood. To decipher whether cell stiffness modulation could increase m... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibrob...
Published: February, 2024

Abstract: There are significant commonalities among several pathologies involving fibroblasts, ranging from auto-immune diseases to fibrosis and cancer. Earl... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Long-term effects of myo-inositol on traumatic brain injury: Epigen...
Published: January, 2024

Abstract: Background and purpose Traumatic brain injury (TBI) and its consequences remain great challenges for neurology. Consequences of TBI are associated... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Aseptic loosening around total joint replacement in humans is regul...
Published: January, 2024

Abstract: Background: Total joint replacement for osteoarthritis is one of the most successful surgical procedures in modern medicine. However, aseptic ... Read more »

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D-Plex small RNA-seq

CompDuplex: Accurate detection of somatic mutations by duplex-seq w...
Published: January, 2024

Abstract: Somatic mutations continuously accumulate in the human genome, posing vulnerabilities towards aging and increased risk of vario... Read more »

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Tagmentase

Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor...
Published: January, 2024

Abstract: The POU2F3-POU2AF2/3 (OCA-T1/2) transcription factor complex is the master regulator of the tuft cell lineage and tuft cell-like small cell lung ca... Read more »

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Bioruptor iDeal ChIP-seq Kit for Transcription Factors

DNA methylome, R-loop and clinical exome profiling of patients with...
Published: January, 2024

Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the death of motor neurons, the aetiology of which is es... Read more »

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Premium RRBS Kit

Gestational Caloric Restriction Alters Adipose Tissue Methylome and...
Published: January, 2024

Abstract: Limited nutrient supply to the fetus results in physiologic and metabolic adaptations that have unfavorable consequences in the offspring. In a swi... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Matched analysis of detailed peripheral blood and tumor immune micr...
Published: January, 2024

Abstract: Background: Bladder cancer and therapy responses hinge on immune profiles in the tumor microenvironment (TME) and blood, yet studies linking t... Read more »

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Infinium Human MethylationEPIC Array Service

Integrative functional genomic analyses identify genetic variants i...
Published: January, 2024

Abstract: Skin color is highly variable in Africans, yet little is known about the underlying molecular mechanism. Here we applied massively parallel reporte... Read more »

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Tagmentase

An inappropriate decline in ribosome levels drives a diverse set of...
Published: January, 2024

Abstract: Many neurodevelopmental defects are linked to perturbations in genes involved in housekeeping functions, such as those encoding ribosome biogenesis... Read more »

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D-Plex small RNA-seq

Promoter DNA methylation patterns in oral, laryngeal and oropharyng...
Published: January, 2024

Abstract: Differentially methylated regions (DMRs) can be used as head and neck squamous cell carcinoma (HNSCC) diagnostic, prognostic and therapeutic target... Read more »

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MagMeDIP kit

Substrate stiffness promotes vascular smooth muscle cell calcificat...
Published: January, 2024

Abstract: Background: Vascular calcification (VC) is a prevalent independent risk factor for adverse cardiovascular events and is associated with diabet... Read more »

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iDeal ChIP-qPCR

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pl...
Published: January, 2024

Abstract: Human naïve pluripotent stem cells (nPSCs) can differentiate into extra-embryonic trophectoderm (TE), a critical step in the generation of the... Read more »

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ATAC-seq

Diagnostic Algorithm to Subclassify Atypical Spitzoid Tumors in Low...
Published: December, 2023

Abstract: Current diagnostic algorithms are insufficient for the optimal clinical and therapeutic management of cutaneous spitzoid tumors, particularly atypi... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

The ncBAF complex regulates transcription in AML through H3K27ac se...
Published: December, 2023

Abstract: The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemog... Read more »

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Tagmentase

In vitro production of cat-restricted Toxoplasma pre-sexual stages
Published: December, 2023

Abstract: Sexual reproduction of Toxoplasma gondii, confined to the felid gut, remains largely uncharted owing to ethical concerns regarding the use of ... Read more »

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Antibody IPure kit iDeal ChIP-seq Kit for Transcription Factors ATAC-seq

Challenges in characterization of transcriptomes of extracellular v...
Published: December, 2023

Abstract: Since its original discovery over a decade ago, extracellular RNA (exRNA) has been found in all biological fluids. Furthermore, extracellular micro... Read more »

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D-Plex small RNA-seq

SMARCB1 loss activates patient-specific distal oncogenic enhancers ...
Published: December, 2023

Abstract: Malignant rhabdoid tumor (MRT) is a highly malignant and often lethal childhood cancer. MRTs are genetically defined by bi-allelic inactivating mut... Read more »

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Microplex Library Preparation kit

The genetic landscape of origins of replication in P. falciparum
Published: December, 2023

Abstract: Various origin mapping approaches have enabled genome-wide identification of origins of replication (ORI) in model organisms, but only a few studie... Read more »

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Microplex Library Preparation kit

DAXX promotes centromeric stability independently of ATRX by preven...
Published: December, 2023

Abstract: Maintaining chromatin integrity at the repetitive non-coding DNA sequences underlying centromeres is crucial to prevent replicative stress, DNA bre... Read more »

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iDeal ChIP-qPCR

An enriched maternal environment and stereotypies of sows different...
Published: December, 2023

Abstract: Epigenetic mechanisms are important modulators of neurodevelopmental outcomes in the offspring of animals challenged during pregnancy. Pregnant sow... Read more »

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Antibody

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