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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

PRKG1 hinders myogenic differentiation and predicts response to AKT...
Published: November, 2025
Abstract: Rhabdomyosarcoma (RMS) is marked by a myogenesis differentiation blockade, and while the AKT/mTOR pathway is universally activated, its pharmac... Read more »
EZHIP restricts noncanonical PRC2 binding and regulates H3K27me3 in...
Published: November, 2025
Abstract: In mice, the repressive histone mark H3K27me3 undergoes both region-specific inheritance and erasure during the parental-to-embryonic transition,... Read more »
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D-Plex small RNA-seq
Epigenomics of embryogenesis in turbot
Published: November, 2025
Abstract: Embryogenesis is the foundational step of ontogeny, where a complex organism emerges from a single totipotent cell. This process is orchestrate... Read more »
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Antibody ChIPmentation
Single-cell, multi-region profiling of the macaque brain across the...
Published: November, 2025
Abstract: Brain aging is a complex process with profound health and societal consequences. However, the molecular and cellular pathways that govern its tem... Read more »
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Tagmentase
The brain neurovascular epigenome and its association with dementia
Published: October, 2025
Abstract: Cerebral small vessel disease (SVD) is frequently comorbid with Alzheimer's disease (AD), and brain endothelial cells (BECs) express genes associ... Read more »
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Antibody Tagmentase
Disease-specific epigenetic deregulation of enhancers, transposons,...
Published: October, 2025
Abstract: Background: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), characterized by a fusion between the PML and RAR... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Upregulation of ALDH1 as an adaptive epigenetic response to anthrac...
Published: October, 2025
Abstract: Acute myeloid leukemia (AML) is a genetically heterogeneous malignancy characterized by the clonal proliferation of undifferentiated myeloid pr... Read more »
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Antibody Microplex Library Preparation kit
Retinoic acid and ascorbate synergize to suppress myeloid leukemia ...
Published: October, 2025
Abstract: Enhancing ten-eleven translocation 2 (TET2) activity through genetic or pharmacologic approaches, such as ascorbate supplementation, can slow mye... Read more »
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Antibody ATAC-seq
Effects of Maternal Peanut Intake and Breastfeeding Duration on Off...
Published: October, 2025
Abstract: Emerging evidence suggests that maternal diet during pregnancy and breastfeeding may influence epigenetic modifications in offspring genes related ... Read more »
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Infinium Human MethylationEPIC Array Service
Arginine Metabolism Supports De Novo Pyrimidine Biosynthesis to Blo...
Published: October, 2025
Abstract: Incompletely understood mechanisms serve to maintain Epstein-Barr virus (EBV) latency in most B-cell states, in which viral oncogene(s) are express... Read more »
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MagMeDIP kit
Seed structure and phosphorylation in the fuzzy coat impact tau see...
Published: October, 2025
Abstract: Tau misfolding into β-sheet–rich filaments and subsequent recruitment of monomeric tau are central to Alzheimer’s disease (AD) pat... Read more »
Tea-derived extracellular vesicles-mediated PDRN delivery activates...
Published: October, 2025
Abstract: The clinical translation of polydeoxyribonucleotide (PDRN), a bioactive agent with anti-inflammatory and tissue-repair properties, is hindered by s... Read more »
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Bioruptor Plus
Multigenerational temperature effects on paternal epigenetic inheri...
Published: October, 2025
Abstract: Environmental changes can induce epigenetic modifications, influencing gene expression, phenotype, and species adaptation. This study investigate... Read more »
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Premium RRBS Kit
PHF19 drives the formation of PRC2 clusters to enhance motility in ...
Published: October, 2025
Abstract: Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and di... Read more »
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Antibody Microplex Library Preparation kit
Global Mapping of Combinatorial Chromatin Regulatory Events Using H...
Published: October, 2025
Abstract: Epigenetic modulators, transcription factors, and chromatin-associated proteins collaboratively regulate essential genomic functions, such as tra... Read more »
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Tagmentase
OGFOD1 enables AML chemo- and nutrient stress resistance by regulat...
Published: October, 2025
Abstract: Acute myeloid leukemia (AML) commonly relapses after initial chemotherapy response. We assessed metabolic adaptations in chemoresistant cells in ... Read more »
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D-Plex small RNA-seq
Disruption of histone acetylation homeostasis reveals multilayered ...
Published: October, 2025
Abstract: Background: Epigenetic modifications, nucleosome occupancy, and three-dimensional chromatin architecture collectively create a multi-layered, ... Read more »
A Photocaged N-Phosphonopiperidinone as a Selective Photo-Cleavable...
Published: October, 2025
Abstract: The strategic introduction of photocages into chemical probes represents a powerful approach to generate spatiotemporally controlled tools with pro... Read more »
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Bioruptor
Targeting histone H2B acetylated enhanceosomes via p300/CBP degrada...
Published: October, 2025
Abstract: Prostate cancer is driven by oncogenic transcription factor enhanceosomes comprising chromatin and epigenetic regulators. The lysine acetyltran... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
KANSL3 directs transcriptional programs essential for hepatic metab...
Published: October, 2025
Abstract: Liver disease is a leading cause of mortality worldwide. Emerging evidence highlights the significant role of epigenetic regulation in sustaini... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Gene and transposable element expression in response to stress in t...
Published: September, 2025
Abstract: Background: The study of stress response in natural populations is crucial for understanding species local adaptation and evolution. In Drosop... Read more »
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Microplex Library Preparation kit
Role of MNX1-mediated Histone Modifications and PBX Gene Family in ...
Published: September, 2025
Abstract: The t(7;12)(q36;p13) AML subtype in pediatric patients is associated with the upregulation of homeodomain protein MNX1 as the initiating event ... Read more »
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Antibody iDeal ChIP-qPCR
Probing DNA damage in Rett syndrome neurons uncovers a role for MEC...
Published: September, 2025
Abstract: Methyl-CpG-binding protein 2 (MECP2)/Rett syndrome is characterized by a postnatal loss of neurophysiological function and regression of chil... Read more »
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Antibody
Anticancer Activity of Jania rubens in HCT-116 Cells via EMT Suppre...
Published: September, 2025
Abstract: The red seaweed Jania rubens (J. rubens) is prevalent along the Lebanese coast and has drawn attention for its notable antineoplastic p... Read more »
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Antibody
Coordinated control of genome-nuclear lamina interactions by topois...
Published: September, 2025
Abstract: Lamina-associated domains (LADs) are megabase-sized genomic regions anchored to the nuclear lamina (NL). Factors controlling the interactions o... Read more »
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Antibody
PTTG1IP Orchestrates Epithelial–Mesenchymal Transition and DNA Dama...
Published: September, 2025
Abstract: Background: Thyroid cancer progression involves cell-state plasticity in the form of epithelial–mesenchymal transition (EMT), and defect... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Teamwork of clustered low-affinity κB sites and accessory factors r...
Published: September, 2025
Abstract: Non-consensus binding sites of transcription factors (TFs) are often observed within the regulatory elements of genes; however, their effect on... Read more »
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Antibody
XPO1-inhibitor Selinexor induces MGMT expression by activating PKA-...
Published: September, 2025
Abstract: Purpose: The temozolomide (TMZ) resistance mechanisms in MGMT-promoter methylated IDH wildtype glioblastoma (GBM) tumors are poorly ... Read more »
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Antibody
Deep Intronic SVA_E Insertion Identified as the Most Common Pathoge...
Published: September, 2025
Abstract: Background and objectives: Canavan disease (CD) is a neurodegenerative disorder in which biallelic pathogenic variants in ASPA resul... Read more »
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Megaruptor
Epigenomic Heterogeneity of Non-Functional Pancreatic Neuroendocrin...
Published: September, 2025
Abstract: Non-functional pancreatic neuroendocrine tumors (NF-PanNETs) account for the majority of neuroendocrine neoplasms arising in the pancreas and e... Read more »
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Tagmentase

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