Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Mission SpaceX CRS-19 RRRM-1 space flight induced skin genomic plas...
Published: December, 2024

Abstract: Highlights Exposure to space environment causes genome-wide adaptive epigenetic changes Space-exposure adaptive genome-wide changes a... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Assessing the impact of whole genome duplication on gene expression...
Published: December, 2024

Abstract: Whole genome duplication (WGD) generates new genetic material that can contribute to the evolution of the regulation of developmental processes and... Read more »

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ATAC-seq
Histone variant H3.5 in testicular cell differentiation and its int...
Published: December, 2024

Abstract: Testicular cell differentiation is a highly regulated process, essential for male reproductive health. The histone variant H3.5 is apparently a cri... Read more »

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MagMeDIP kit
TurboCas: A method for locus-specific labeling of genomic regions a...
Published: December, 2024

Abstract: Regulation of gene expression during development and stress response requires the concerted action of transcription factors and chromatin-binding p... Read more »

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CRISPR
The oncogenic lncRNA MIR503HG suppresses cellular senescence counte...
Published: December, 2024

Abstract: Background The androgen receptor (AR), a ligand-dependent transcription factor, plays a key role in regulating prostate cancer (PCa) growth. The n... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
RNA Pol-II transcripts in nucleolar associated domains of cancer ce...
Published: December, 2024

Abstract: We performed a comparative study of the non-ribosomal gene content of nucleoli from seven cancer cell lines, using identical methods of purificatio... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones
Single chromatin fiber profiling and nucleosome position mapping in...
Published: December, 2024

Abstract: Motivation Nucleosomes are the basic unit of chromatin, but genome-scale maps of nucleosome positioning along chromatin fibers do not exist for ... Read more »

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Megaruptor
Independent evaluation of an 11-CpG panel for age estimation in blood
Published: December, 2024

Abstract: Highlights A set of 11 CpGs for age prediction was investigated in 148 Danish blood samples. Assay optimization improved covera... Read more »

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Premium Bisulfite Kit
Exploring the Epigenetic Landscape of Spermatozoa: Impact of Oxidat...
Published: December, 2024

Abstract: Reproductive success is dependent on gamete integrity, and oxidative stress alters male nuclei, meaning that no DNA repair is possible due to chrom... Read more »

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Antibody
PDGFRA is a conserved HAND2 effector during early cardiac development
Published: December, 2024

Abstract: The basic helix–loop–helix transcription factor HAND2 has multiple roles during vertebrate organogenesis, including cardiogenesis. Howe... Read more »

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True MicroChIP kit
EOMES establishes mesoderm and endoderm differentiation potential t...
Published: December, 2024

Abstract: Highlights Enhancer chromatin is dynamically remodeled during mesoderm/endoderm (ME) differentiation Global ME enhancer accessi... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
Plasma cell-free DNA chromatin immunoprecipitation profiling depict...
Published: December, 2024

Abstract: Cell phenotype underlies prostate cancer presentation and treatment resistance and can be regulated by epigenomic features. However, the osteotropi... Read more »

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Antibody
Spatial organizations of heterochromatin underpin nuclear structura...
Published: December, 2024

Abstract: Highlights Cardiomyocytes acquire characteristic spatial organizations of heterochromatin (SOH) High levels of H2B-mCherry disr... Read more »

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ATAC-seq
Interferon-gamma rescues FK506 dampened dendritic cell calcineurin-...
Published: December, 2024

Abstract: IScience Highlights Calcineurin inhibitors block DC maturation in response to A. fumigatus Lack of DC maturation impairs T... Read more »

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Antibody IPure kit Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones
ETV2/ER71 regulates hematovascular lineage generation and vasculari...
Published: December, 2024

Abstract: Highlights Interaction of ETV2 and KDM4A decreases H3K9 trimethylation on hematovascular genes. ETV2 and KDM4A cooperatively re... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia t...
Published: December, 2024

Abstract: To increase antibody affinity against pathogens, positively selected GC-B cells initiate cell division in the light zone (LZ) of germinal centers (... Read more »

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Microplex Library Preparation kit
Gene mobility elements mediate cell type specific genome organizati...
Published: December, 2024

Abstract: Understanding the level of genome organization that governs gene regulation remains a challenge despite advancements in chromatin profiling techniq... Read more »

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Tagmentase
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive ge...
Published: November, 2024

Abstract: Highlights Degradation of NUP98-fp halts nascent transcription of key oncogenes within 1 h NUP98-fp loss results in accumulat... Read more »

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Antibody
HIRA protects telomeres against R-loop-induced instability in ALT c...
Published: November, 2024

Abstract: Highlights HIRA establishes greater telomeric chromatin accessibility after ATRX-DAXX loss Deposition of new H3.3 by HIRA-UBN r... Read more »

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Tagmentase
Peroxiredoxin 1-Toll-like receptor 4-p65 axis inhibits receptor act...
Published: November, 2024

Abstract: Peroxiredoxin 1 (PRDX1), an intracellular antioxidant enzyme, has emerged as a regulator of inflammatory responses via Toll-like receptor 4 (TLR4) ... Read more »

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Antibody
Cells transit through a quiescent-like state to convert to neurons ...
Published: November, 2024

Abstract: While transcription factors (TFs) provide essential cues for directing and redirecting cell fate, TFs alone are insufficient to drive cells to adop... Read more »

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Tagmentase
Enhancing single-cell ATAC sequencing with formaldehyde fixation, c...
Published: November, 2024

Abstract: The assay for transposase-accessible chromatin using sequencing (ATAC-seq) revolutionized the field of epigenetics since its emergence by providing... Read more »

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Tagmentase
The Novel Direct AR Target Gene Annexin A2 Mediates Androgen-Induce...
Published: November, 2024

Abstract: Clinical trials for prostate cancer (PCa) patients have implemented the bipolar androgen therapy (BAT) that includes the treatment with supraphysio... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
TEAD-targeting small molecules induce a cofactor switch to regulate...
Published: November, 2024

Abstract: TEAD proteins are the main transcriptional effectors of the Hippo signaling pathway and a pharmacological target in oncology. Most TEAD-targeting s... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services
Steroid receptor-assisted loading modulates transcriptional respons...
Published: November, 2024

Abstract: Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biological processes, with significant implications in... Read more »

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Tagmentase
Nuclear localization of MTHFD2 is required for correct mitosis prog...
Published: November, 2024

Abstract: Subcellular compartmentalization of metabolic enzymes establishes a unique metabolic environment that elicits specific cellular functions. Indeed, ... Read more »

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Antibody
Claudin-1 as a potential marker of stress-induced premature senesce...
Published: November, 2024

Abstract: Cellular senescence, a permanent state of cell cycle arrest, can result either from external stress and is then called stress-induced premature sen... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Engineered PsCas9 enables therapeutic genome editing in mouse liver...
Published: November, 2024

Abstract: Clinical implementation of therapeutic genome editing relies on efficient in vivo delivery and the safety of CRISPR-Cas tools. Previously, we ident... Read more »

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Tagmentase
AistSeq: An In-House Tn5-Based Plasmid Sequencing Platform Using A ...
Published: November, 2024

Abstract: Sequence verification of plasmids is a fundamental process in synthetic biology. For plasmid sequence verification using next-generation sequencing... Read more »

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Tagmentase
ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophag...
Published: November, 2024

Abstract: Anti-PD-L1-based combination immunotherapy has become the first-line treatment for unresectable hepatocellular carcinoma (HCC). However, the object... Read more »

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Microplex Library Preparation kit

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