Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Association of DNA methylation signatures with premature ageing and...
Published: December, 2023

Abstract: Patients with end-stage kidney disease (ESKD) display features of premature aging. There is strong evidence that changes in DNA methylation (DNAm) ... Read more »

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Infinium Human MethylationEPIC Array Service
SUMO protease FUG1, histone reader AL3 and the PRC1 Complex areinte...
Published: December, 2023

Abstract: Epigenetic gene silencing induced by expanded repeats can cause diverse phenotypes ranging from severe growth defects in plants to genetic diseases... Read more »

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Antibody
KDM6B drives epigenetic reprogramming associated with lymphoid stro...
Published: November, 2023

Abstract: Mature lymphoid stromal cells (LSCs) are key organizers of immune responses within secondary lymphoid organs. Similarly, inflammation-driven tertia... Read more »

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Antibody
LEO1 Is Required for Efficient Entry into Quiescence, Control of H3...
Published: November, 2023

Abstract: (1) Background: The LEO1 (Left open reading frame 1) protein is a conserved subunit of the PAF1C complex (RNA polymerase II-associated factor 1 com... Read more »

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iDeal ChIP-seq Kit for Histones
Guidelines for Performing Ribosome Profiling in Plants Including St...
Published: November, 2023

Abstract: Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Across differen... Read more »

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D-Plex small RNA-seq
Integrated multiplexed assays of variant effect reveal cis-regulato...
Published: November, 2023

Abstract: Multiplexed assays of variant effect are powerful methods to profile the consequences of rare variants on gene expression and organismal fitness. Y... Read more »

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D-Plex small RNA-seq
Vaginal microbes alter epithelial transcriptomic and epigenomic mod...
Published: November, 2023

Abstract: The cervicovaginal microbiome is highly associated with women's health with microbial communities dominated by Lactobacillus spp. being c... Read more »

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ATAC-seq
H3K9 methylation patterns during somatic embryogenic competenceexpr...
Published: November, 2023

Abstract: The capacity to regenerate is intrinsic to plants and is the basis of natural asexual propagation and artificial cloning. Despite there are differe... Read more »

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Antibody
The Ribosome Assembly Factor Reh1 is Released from the Polypeptide ...
Published: October, 2023

Abstract: Assembly of functional ribosomal subunits and successfully delivering them to the translating pool is a prerequisite for protein synthesis and cell... Read more »

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D-Plex small RNA-seq
Inflammatory stress-mediated chromatin changes underlie dysfunction...
Published: October, 2023

Abstract: Inflammatory stresses underlie endothelial dysfunction and contribute to the development of chronic cardiovascular disorders such as atherosclerosi... Read more »

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Chromatin Profiling (ChIP-seq) Services ATAC-seq
A transgenic mice model of retinopathy of cblG-type inherited disor...
Published: October, 2023

Abstract: BACKGROUND: MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolis... Read more »

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Newly added
G-quadruplexes of KSHV oriLyt play important roles in promoting lyt...
Published: October, 2023

Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes distinct origins of DNA replication (origin of replications) during the latent and lytic ph... Read more »

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Newly added
ARID1A governs the silencing of sex-linked transcription during mal...
Published: September, 2023

Abstract: We present evidence implicating the BAF (BRG1/BRM Associated Factor) chromatin remodeler in meiotic sex chromosome inactivation (MSCI). By immunofl... Read more »

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Tagmentase
Knockout of the longevity gene Klotho perturbs aging- and Alzheimer...
Published: September, 2023

Abstract: Overexpression of the longevity gene Klotho prolongs, while its knockout shortens lifespan and impairs cognition via altered fibroblast growth fact... Read more »

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D-Plex small RNA-seq
A Type II-B Cas9 nuclease with minimized off-targets and reduced ch...
Published: September, 2023

Abstract: Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as genome editors, but their promiscuous nuclease activity often ... Read more »

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Tagmentase
Combined Analysis of mRNA Expression and Open Chromatin in Microglia
Published: August, 2023

Abstract: The advance of single-cell RNA-sequencing technologies in the past years has enabled unprecedented insights into the complexity and heterogeneity o... Read more »

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Tagmentase
Volumetric imaging of an intact organism by a distributed molecular...
Published: August, 2023

Abstract: Lymphatic, nervous, and tumoral tissues, among others, exhibit physiology that emerges from three-dimensional interactions between genetically uniq... Read more »

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Tagmentase
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »

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Newly added
FACT regulates pluripotency through proximal and distal regulation ...
Published: August, 2023

Abstract: Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in plu... Read more »
Cerebrospinal fluid methylome-based liquid biopsies for accuratemal...
Published: August, 2023

Abstract: BACKGROUND: Resolving the differential diagnosis between brain metastases (BM), glioblastomas (GBM), and central nervous system lymphomas (CNSL) is... Read more »

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MagMeDIP kit IPure kit
Nuclear proinflammatory cytokine S100A9 enhances expression of huma...
Published: August, 2023

Abstract: Transcription of the human papillomavirus (HPV) oncogenes, and , is regulated by the long control region (LCR) of the viral genome. Although vario... Read more »

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Newly added
A high-throughput screening assay for silencing established HIV-1 m...
Published: August, 2023

Abstract: HIV-infected macrophages are long-lived cells that represent a barrier to functional cure. Additionally, low-level viral expression by central nerv... Read more »

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Newly added
Transgenerational endocrine disruptor effects of cadmium in zebrafi...
Published: August, 2023

Abstract: Evidence has emerged that environmentally-induced epigenetic changes can have long-lasting effects on gene transcription across generations. These ... Read more »

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MagMeDIP kit
Transcription factor EGR2 controls homing and pathogenicity of T17c...
Published: August, 2023

Abstract: CD4 T helper 17 (T17) cells protect barrier tissues but also trigger autoimmunity. The mechanisms behind these opposing processes remain unclear. H... Read more »

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CUT&Tag
ThPOK is a critical multifaceted regulator of myeloid lineagedevelo...
Published: August, 2023

Abstract: The transcription factor ThPOK (encoded by Zbtb7b) is well known for its role as a master regulator of CD4 lineage commitment in the thymus. Here, ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
Differentiation block in acute myeloid leukemia regulated by intron...
Published: August, 2023

Abstract: Iroquois transcription factor gene IRX3 is highly expressed in 20–30\% of acute myeloid leukemia (AML) and contributes to the pa... Read more »

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MagMeDIP kit IPure kit Microplex Library Preparation kit ChIP Cross-link Gold
Zfp296 knockout enhances chromatin accessibility and induces a uniq...
Published: July, 2023

Abstract: The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following dif... Read more »

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Newly added
Perturbed epigenetic transcriptional regulation in AML with IDH mut...
Published: July, 2023

Abstract: Isocitrate dehydrogenase (IDH) mutations are found in 20\% of acute myeloid leukemia (AML) patients. However, only 30-40\% of the patients respond ... Read more »

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Newly added
Zfp296 knockout enhances chromatin accessibility and induces a uniq...
Published: July, 2023

Abstract: The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following dif... Read more »

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Antibody Tagmentase
Mediator 1 ablation induces enamel-to-hair lineage conversion in mi...
Published: July, 2023

Abstract: Postnatal cell fate is postulated to be primarily determined by the local tissue microenvironment. Here, we find that Mediator 1 (Med1) dependent e... Read more »

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IPure kit iDeal ChIP-seq Kit for Transcription Factors

 


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