Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Ca...
Published: October, 2018

Abstract: Perturbed epigenomic programs play key roles in tumorigenesis, and chromatin modulators are candidate therapeutic targets in various human cancer t... Read more »

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Antibody
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcin...
Published: October, 2018

Abstract: Understanding general principles that safeguard cellular identity should reveal critical insights into common mechanisms underlying specification o... Read more »

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Antibody Microplex Library Preparation kit
RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and ...
Published: October, 2018

Abstract: Precisely deciphering the molecular mechanisms of age-related memory loss is crucial to create appropriate therapeutic interventions. We have previ... Read more »

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LowCell ChIP kit IPure kit
The Genomic Basis of Color Pattern Polymorphism in the Harlequin La...
Published: October, 2018

Abstract: Many animal species comprise discrete phenotypic forms. A common example in natural populations of insects is the occurrence of different color pat... Read more »

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Megaruptor
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms.
Published: October, 2018

Abstract: During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, ... Read more »

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Antibody
Caenorhabditis elegans sperm carry a histone-based epigenetic memor...
Published: October, 2018

Abstract: Paternal contributions to epigenetic inheritance are not well understood. Paternal contributions via marked nucleosomes are particularly understudi... Read more »

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IP-Star Compact Microplex Library Preparation kit
Oxidative stress in sperm affects the epigenetic reprogramming in e...
Published: October, 2018

Abstract: BACKGROUND: Reactive oxygen species (ROS)-induced oxidative stress is well known to play a major role in male infertility. Sperm are sensitive to R... Read more »

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Antibody
Long-read sequence capture of the hemoglobin gene clusters across g...
Published: October, 2018

Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »

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Megaruptor
Promoter bivalency favors an open chromatin architecture in embryon...
Published: October, 2018

Abstract: In embryonic stem cells (ESCs), developmental gene promoters are characterized by their bivalent chromatin state, with simultaneous modification by... Read more »

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Antibody
Macrophage-specific MHCII expression is regulated by a remote enha...
Published: October, 2018

Abstract: MHCII in antigen-presenting cells (APCs) is a key regulator of adaptive immune responses. Expression of MHCII genes is controlled by the transcript... Read more »

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Beads
PWWP2A binds distinct chromatin moieties and interacts with an MTA1...
Published: October, 2018

Abstract: Chromatin structure and function is regulated by reader proteins recognizing histone modifications and/or histone variants. We recently identified ... Read more »

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Antibody Microplex Library Preparation kit
SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a ...
Published: October, 2018

Abstract: Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disea... Read more »

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Antibody
Convergent evolution of complex genomic rearrangements in two funga...
Published: October, 2018

Abstract: Meiotic drive is widespread in nature. The conflict it generates is expected to be an important motor for evolutionary change and innovation. In th... Read more »

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IPure kit Microplex Library Preparation kit
H3K4me2 and WDR5 enriched chromatin interacting long non-coding RNA...
Published: October, 2018

Abstract: Recently lncRNAs have been implicated in the sub-compartmentalization of eukaryotic genome via genomic targeting of chromatin remodelers. To explor... Read more »

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LowCell ChIP kit iDeal ChIP-seq Kit for Transcription Factors
Demethylation of ITGAV accelerates osteogenic differentiation in a ...
Published: October, 2018

Abstract: Trauma-induced heterotopic ossification is an intriguing phenomenon involving the inappropriate ossification of soft tissues within the body such a... Read more »
Angiotensin II induced CSF1 transcription is mediated by a crosstal...
Published: October, 2018

Abstract: Endothelium-derived colony stimulating factor (CSF1) plays a key role in a range of human pathologies. Angiotensin II (Ang II) has been documented ... Read more »

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Antibody
Generation of an equine biobank to be used for Functional Annotatio...
Published: October, 2018

Abstract: The Functional Annotation of Animal Genomes (FAANG) project aims to identify genomic regulatory elements in both sexes across multiple stages of de... Read more »

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iDeal ChIP-seq Kit for Histones
Differential Methylation of H3K79 Reveals DOT1L Target Genes and Fu...
Published: October, 2018

Abstract: The disruptor of telomeric silencing 1-like (DOT1L) mediates methylation of histone H3 at position lysine 79 (H3K79). Conditional knockout of Dot1l... Read more »

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Antibody
The long non-coding RNA NEAT1 and nuclear paraspeckles are upregula...
Published: October, 2018

Abstract: The long non-coding RNA (lncRNA) NEAT1 is the architectural component of nuclear paraspeckles, and has recently gained considerable attention as it... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
IFN-γ immune priming of macrophages in vivo induces prolonged STAT1...
Published: October, 2018

Abstract: Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of th... Read more »

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IPure kit
Accurate annotation of accessible chromatin in mouse and human prim...
Published: October, 2018

Abstract: Extensive and accurate chromatin remodeling is essential during primordial germ cell (PGC) development for the perpetuation of genetic information ... Read more »

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Antibody
Differential Methylation of H3K79 Reveals DOT1L Target Genes and Fu...
Published: October, 2018

Abstract: The disruptor of telomeric silencing 1-like (DOT1L) mediates methylation of histone H3 at position lysine 79 (H3K79). Conditional knockout of Dot1l... Read more »

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Antibody
ΔNp63-driven recruitment of myeloid-derived suppressor cells promot...
Published: October, 2018

Abstract: Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastas... Read more »

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ChIP-seq
H3K4/K9 acetylation and Lr28-mediated expression of six leaf rust r...
Published: October, 2018

Abstract: Development of leaf rust-resistant cultivars is a priority during wheat breeding, since leaf rust causes major losses in yield. Resistance against ... Read more »

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Beads
Prospective Isolation and Characterization of Genetically and Funct...
Published: October, 2018

Abstract: Intra-tumor heterogeneity caused by clonal evolution is a major problem in cancer treatment. To address this problem, we performed label-free quant... Read more »

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Microplex Library Preparation kit
Directional high-throughput sequencing of RNAs without gene-specifi...
Published: October, 2018

Abstract: Ribosomal RNA analysis is a useful tool for characterization of microbial communities. However, the lack of broad-range primers has hampered the si... Read more »

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CATS
SOX4 inhibits oligodendrocyte differentiation of embryonic neural s...
Published: October, 2018

Abstract: SOX4 has been shown to promote neuronal differentiation both in the adult and embryonic neural progenitors. Ectopic SOX4 expression has also been s... Read more »

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Antibody
Cellular localization of the cell cycle inhibitor Cdkn1c controls g...
Published: October, 2018

Abstract: Adult skeletal muscle maintenance and regeneration depend on efficient muscle stem cell (MuSC) functions. The mechanisms coordinating cell cycle wi... Read more »

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Antibody
Integrated analysis of DNA methylation profiling and gene expressio...
Published: October, 2018

Abstract: BACKGROUND: Aberrant DNA methylation occurs frequently in cancer. The aim of this study was to identify novel methylation markers in lung cancer in... Read more »

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Antibody
Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Choles...
Published: October, 2018

Abstract: The mechanisms underlying sterol transport in mammalian cells are poorly understood. In particular, how cholesterol internalized from HDL is made a... Read more »

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Master Mix

Events

  • Japanese Biochemical Society
    Yokohama
    Sep 18-Sep 20, 2019
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    Sep 19, 2019
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