Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A lipodystrophy-causing lamin A mutant alters conformation and epig...
Published: September, 2017

Abstract: Mutations in the Lamin A/C (LMNA) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic s... Read more »

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Antibody
Chromosome contacts in activated T cells identify autoimmune diseas...
Published: September, 2017

Abstract: BACKGROUND: Autoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. ... Read more »

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IP-Star Antibody
Transcription of synaptic plasticity-related genes in patients with...
Published: September, 2017

Abstract: Objective: To investigate DNA methylation and hydroxymethylation in patients with somnipathy combined with type 2 diabetes, and to explore the effe... Read more »

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MeDIP kit
High-Resolution Chromatin Immunoprecipitation: ChIP-Sequencing
Published: September, 2017

Abstract: Chromatin immunoprecipitation (ChIP) coupled with next-generation sequencing (NGS) is widely used for studying the nucleoprotein components that ar... Read more »

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IPure kit
Epigenome profiling and editing of neocortical progenitor cells dur...
Published: September, 2017

Abstract: The generation of neocortical neurons from neural progenitor cells (NPCs) is primarily controlled by transcription factors binding to DNA in the co... Read more »

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LowCell ChIP kit IPure kit Microplex Library Preparation kit
Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-O...
Published: September, 2017

Abstract: Root growth is modulated by environmental factors and depends on cell production in the root meristem (RM). New cells in the meristem are generated... Read more »

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IPure kit
SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus...
Published: August, 2017

Abstract: The structural maintenance of chromosomes (SMC) complex plays an important role in chromosome organization and segregation in most living organisms... Read more »

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ChIP-qPCR
Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits in...
Published: August, 2017

Abstract: Abstract Problem Heightened maternal stress affects trophoblast function and increases risk for adverse pregnancy outcomes. Methods of Stu... Read more »
Epigenetic variation between urban and rural populations of Darwin'...
Published: August, 2017

Abstract: Background The molecular basis of evolutionary change is assumed to be genetic variation. However, growing evidence suggests that epigenetic m... Read more »

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Antibody
Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichme...
Published: August, 2017

Abstract: Background Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure... Read more »

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MagMeDIP kit
A lncRNA fine tunes the dynamics of a cell state transition involvi...
Published: August, 2017

Abstract: Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated f... Read more »

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Antibody
Myc Regulates Chromatin Decompaction and Nuclear Architecture durin...
Published: August, 2017

Abstract: 50 years ago, Vincent Allfrey and colleagues discovered that lymphocyte activation triggers massive acetylation of chromatin. However, the molecula... Read more »

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Antibody
Transcriptome sequencing in pediatric acute lymphoblastic leukemia ...
Published: August, 2017

Abstract: BACKGROUND: Structural chromosomal rearrangements that lead to expressed fusion genes are a hallmark of acute lymphoblastic leukemia (ALL). In t... Read more »

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Microplex Library Preparation kit
Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in hum...
Published: August, 2017

Abstract: Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (... Read more »

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Antibody
High Resolution Mapping of Chromatin Conformation in Cardiac Myocyt...
Published: August, 2017

Abstract: Background -Cardiovascular disease is associated with epigenomic changes in the heart, however the endogenous structure of cardiac myocyte chromati... Read more »

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Antibody
Circadian Reprogramming in the Liver Identifies Metabolic Pathways ...
Published: August, 2017

Abstract: The process of aging and circadian rhythms are intimately intertwined, but how peripheral clocks involved in metabolic homeostasis contribute to ag... Read more »

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Antibody
DNMT3B overexpression contributes to aberrant DNA methylation and M...
Published: August, 2017

Abstract: Aberrant DNA methylation is a hallmark of cancer. However, our understanding of how tumor cell-specific DNA methylation patterns are established an... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-...
Published: August, 2017

Abstract: BACKGROUND: The epithelial-to-mesenchymal transition (EMT) enables epithelial cancer cells to acquire mesenchymal features and contributes to me... Read more »

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Antibody
Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methy...
Published: August, 2017

Abstract: During cellular differentiation, genes important for differentiation are expected to be silent in stem/progenitor cells yet can be readily activate... Read more »

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Microplex Library Preparation kit
Coordinate Regulation of TET2 and EBNA2 Control DNA Methylation Sta...
Published: August, 2017

Abstract: Epstein-Barr Virus (EBV) latency and its associated carcinogenesis are regulated by dynamic changes in DNA methylation of both virus and host genom... Read more »

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MagMeDIP kit
The RPMI-1640 vitamin mixture promotes bovine blastocyst developmen...
Published: August, 2017

Abstract: Diverse environmental conditions surrounding preimplantation embryos, including available nutrients, affect their metabolism and development in bot... Read more »

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True MicroChIP kit
Maternal obesity programs increased leptin gene expression in rat m...
Published: August, 2017

Abstract: OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates pred... Read more »

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Antibody
A novel FOXA1/ESR1 interacting pathway: A study of Oncomine™ breast...
Published: August, 2017

Abstract: Forkhead box protein A1 (FOXA1) is essential for the growth and differentiation of breast epithelium, and has a favorable outcome in breast cancer ... Read more »

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Antibody
Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural...
Published: August, 2017

Abstract: Replacement of canonical histones with specialized histone variants promotes altering of chromatin structure and function. The essential histone va... Read more »

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Antibody Microplex Library Preparation kit
Genome-wide screen for differentially methylated long noncoding RNA...
Published: July, 2017

Abstract: The majority of long noncoding RNAs (lncRNAs) is still poorly characterized with respect to function, interactions with protein-coding genes, and m... Read more »

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IP-Star Compact
Increased 5-hydroxymethylation levels in the hippocampus of rat ext...
Published: July, 2017

Abstract: Drug craving and relapse risk during abstinence from cocaine are thought to be caused by persistent changes in transcription and chromatin regulati... Read more »

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Antibody
Unique roles for histone H3K9me states in RNAi and heritable silenc...
Published: July, 2017

Abstract: Heterochromatic DNA domains have important roles in the regulation of gene expression and maintenance of genome stability by silencing repetitive D... Read more »

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Antibody
Krox20 hindbrain regulation incorporates multiple modes of cooperat...
Published: July, 2017

Abstract: Developmental genes can harbour multiple transcriptional enhancers that act simultaneously or in succession to achieve robust and precise spatiotem... Read more »

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Antibody Microplex Library Preparation kit
RNA-binding protein HuR enhances mineralocorticoid signaling in ren...
Published: July, 2017

Abstract: Mineralocorticoid receptor (MR) mediates the sodium-retaining action of aldosterone in the distal nephron. Herein, we decipher mechanisms by which ... Read more »

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HighCell ChIP kit
Ectopic application of the repressive histone modification H3K9me2 ...
Published: July, 2017

Abstract: Hybrid seed lethality as a consequence of interspecies or interploidy hybridizations is a major mechanism of reproductive isolation in plants. This... Read more »

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Antibody Microplex Library Preparation kit

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