Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Allelic H3K27me3 to allelic DNA methylation switch maintains noncan...
Published: December, 2019

Abstract: Faithful maintenance of genomic imprinting is essential for mammalian development. While germline DNA methylation–dependent (canonical) impri... Read more »

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Antibody
Functionally Annotating Regulatory Elements in the Equine Genome Us...
Published: December, 2019

Abstract: One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within anim... Read more »

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Antibody IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Combinatorial action of NF-Y and TALE at embryonic enhancers define...
Published: December, 2019

Abstract: Animal embryogenesis is initiated by maternal factors, but zygotic genome activation (ZGA) shifts regulatory control to the embryo during blastula ... Read more »

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Microplex Library Preparation kit
H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammat...
Published: December, 2019

Abstract: Natural killer (NK) cells are unique players in innate immunity and, as such, an attractive target for immunotherapy. NK cells display immune memor... Read more »

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Antibody
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signa...
Published: December, 2019

Abstract: In breast cancer, Lysine-specific demethylase-1 (LSD1) and other lysine demethylases (KDMs), such as Lysine-specific demethylase 6A also known as U... Read more »

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Antibody
Increased presence and differential molecular imprinting of transit...
Published: December, 2019

Abstract: Psoriasis is a very common chronic inflammatory skin disease characterized by epidermal thickening and scaling resulting from keratinocyte hyperpro... Read more »

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MethylCap
Trained immunity modulates inflammation-induced fibrosis.
Published: December, 2019

Abstract: Chronic inflammation and fibrosis can result from inappropriately activated immune responses that are mediated by macrophages. Macrophages can acqu... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
Mkt1 is required for RNAi-mediated silencing and establishment of h...
Published: December, 2019

Abstract: Constitutive domains of repressive heterochromatin are maintained within the fission yeast genome through self-reinforcing mechanisms involving his... Read more »

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Antibody
A Study of High-Grade Serous Ovarian Cancer Origins Implicates the ...
Published: December, 2019

Abstract: Fallopian tube secretory epithelial cells (FTSECs) are likely the main precursor cell type of high-grade serous ovarian cancers (HGSOCs), but these... Read more »

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Antibody
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 in...
Published: December, 2019

Abstract: As a member of the 11-gene "death-from-cancer" gene expression signature, overexpression of the Ubiquitin-Specific Protease 22 (USP22) was associat... Read more »

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Antibody
SIRT1/2 orchestrate acquisition of DNA methylation and loss of hist...
Published: December, 2019

Abstract: Sirtuins 1 and 2 (SIRT1/2) are two NAD-dependent deacetylases with major roles in inflammation. In addition to deacetylating histones and other pro... Read more »

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Antibody LowCell ChIP kit
Sodium valproate and 5-aza-2'-deoxycytidine differentially modulate...
Published: December, 2019

Abstract: Sodium valproate/valproic acid (VPA), a histone deacetylase inhibitor, and 5-aza-2-deoxycytidine (5-aza-CdR), a DNA methyltransferase 1 (DNMT1) inh... Read more »

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Antibody
Episo: quantitative estimation of RNA 5-methylcytosine at isoform l...
Published: December, 2019

Abstract: MOTIVATION: RNA 5-methylcytosine (m5C) is a type of post-transcriptional modification that may be involved in numerous biological processes and tum... Read more »

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Antibody
Discovery of a new predominant cytosine DNA modification that is li...
Published: November, 2019

Abstract: DNA cytosine modifications are key epigenetic regulators of cellular processes in mammalian cells, with their misregulation leading to varied disea... Read more »

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Microplex Library Preparation kit
A stress-responsive enhancer induces dynamic drug resistance in acu...
Published: November, 2019

Abstract: The drug efflux pump ABCB1 is a key driver of chemoresistance, and high expression predicts for treatment failure in acute myeloid leukemia (AML). ... Read more »

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Microplex Library Preparation kit
DAPK1 loss triggers tumor invasion in colorectal tumor cells.
Published: November, 2019

Abstract: Colorectal cancer (CRC) is one of the leading cancer-related causes of death worldwide. Despite the improvement of surgical and chemotherapeutic tr... Read more »

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CRISPR
Detection of Abrin-Like and Prepropulchellin-Like Toxin Genes and T...
Published: November, 2019

Abstract: The sequenced genome and the leaf transcriptome of a near relative of and was analyzed to characterize the genetic basis of toxin gene expression. ... Read more »

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Megaruptor
MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid c...
Published: November, 2019

Abstract: MicroRNAs (miRNAs) are commonly deregulated in acute myeloid leukemia (AML), affecting critical genes not only through direct targeting, but also t... Read more »

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Antibody
Intra- and inter-generational changes in the cortical DNA methylome...
Published: November, 2019

Abstract: Recent evidence from our lab documents functional resilience to retinal ischemic injury in untreated mice derived from parents exposed to repetitiv... Read more »

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Antibody
R-Loops Promote Antisense Transcription across the Mammalian Genome
Published: November, 2019

Abstract: Widespread antisense long noncoding RNA (lncRNA) overlap with many protein-coding genes in mammals and emanate from gene promoter, enhancer, and te... Read more »

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Antibody
Autoregulation of RCO by Low-Affinity Binding Modulates Cytokinin A...
Published: November, 2019

Abstract: Mechanisms through which the evolution of gene regulation causes morphological diversity are largely unclear. The tremendous shape variation among ... Read more »

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Antibody
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Andr...
Published: November, 2019

Abstract: Androgen-receptor (AR) inhibitors, including enzalutamide, are used for treatment of all metastatic castration-resistant prostate cancers (mCRPCs).... Read more »

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Antibody
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Intera...
Published: November, 2019

Abstract: Mammalian switch/sucrose non-fermentable (mSWI/SNF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the s... Read more »

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Antibody
Plasticity of histone modifications around Cidea and Cidec genes wi...
Published: November, 2019

Abstract: We recently reported that a treatment with tauroursodeoxycholic acid (TUDCA), a secondary bile acid, improved developmentally-deteriorated hepatic ... Read more »

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MethylCap
MicroRNAs Establish the Right-Handed Dominance of the Heart Lateral...
Published: November, 2019

Abstract: Despite their external bilateral symmetry, vertebrates have internal left/right (L/R) asymmetries required for optimal organ function. BMP-induced ... Read more »

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Antibody
NanoSatellite: accurate characterization of expanded tandem repeat ...
Published: November, 2019

Abstract: Technological limitations have hindered the large-scale genetic investigation of tandem repeats in disease. We show that long-read sequencing with ... Read more »

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Megaruptor
Lithium treatment reverses irradiation-induced changes in rodent ne...
Published: November, 2019

Abstract: Cranial radiotherapy in children has detrimental effects on cognition, mood, and social competence in young cancer survivors. Treatments harnessing... Read more »

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MagMeDIP kit Antibody
Sperm DNA Methylation Epimutation Biomarkers for Male Infertility a...
Published: November, 2019

Abstract: Male factor infertility is increasing and recognized as playing a key role in reproductive health and disease. The current primary diagnostic appro... Read more »

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Antibody
Distinct CoREST complexes act in a cell-type-specific manner.
Published: November, 2019

Abstract: CoREST has been identified as a subunit of several protein complexes that generate transcriptionally repressive chromatin structures during develop... Read more »

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Microplex Library Preparation kit
Identification and Massively Parallel Characterization of Regulator...
Published: November, 2019

Abstract: Epigenomic regulation and lineage-specific gene expression act in concert to drive cellular differentiation, but the temporal interplay between the... Read more »

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LowCell ChIP kit IPure kit

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