Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Embryonic germ cell extracts erase imprinted genes and improve the ...
Published: July, 2018

Abstract: Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies hav... Read more »

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MagMeDIP kit
SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylat...
Published: July, 2018

Abstract: Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves... Read more »

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Bioruptor IP-Star Antibody
DNA methylation and genetic degeneration of the Y chromosome in the...
Published: July, 2018

Abstract: BACKGROUND: S. latifolia is a model organism for the study of sex chromosome evolution in plants. Its sex chromosomes include large regions in whic... Read more »
A Somatically Acquired Enhancer of the Androgen Receptor Is a Nonco...
Published: July, 2018

Abstract: Increased androgen receptor (AR) activity drives therapeutic resistance in advanced prostate cancer. The most common resistance mechanism is amplif... Read more »

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Antibody
A LINE1-Nucleolin Partnership Regulates Early Development and ESC I...
Published: July, 2018

Abstract: Transposable elements represent nearly half of mammalian genomes and are generally described as parasites, or "junk DNA." The LINE1 retrotransposon... Read more »

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LowCell ChIP kit
LSD1-ERRα complex requires NRF1 to positively regulate transcriptio...
Published: July, 2018

Abstract: Lysine-specific demethylase 1 (LSD1) exerts dual effects on histone H3, promoting transcriptional repression via Lys4 (H3K4) demethylation or trans... Read more »

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iDeal ChIP-seq Kit for Histones
TRPM7 controls mesenchymal features of breast cancer cells by tensi...
Published: July, 2018

Abstract: Mechanically induced signaling pathways are important drivers of tumor progression. However, if and how mechanical signals affect metastasis or the... Read more »

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Antibody
Enhancer-driven transcriptional regulation is a potential key deter...
Published: June, 2018

Abstract: Obesity is characterized by the excess of body fat leading to impaired health. Abdominal fat is particularly harmful and is associated with cardiov... Read more »

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Microplex Library Preparation kit
An Integrated and Semiautomated Microscaled Approach to Profile Cis...
Published: June, 2018

Abstract: Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory ... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Gene promoter and exon DNA methylation changes in colon cancer deve...
Published: June, 2018

Abstract: BACKGROUND: DNA mutations occur randomly and sporadically in growth-related genes, mostly on cytosines. Demethylation of cytosines may lead to gene... Read more »

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IP-Star MethylCap
Thyroid hormone receptor and ERRα coordinately regulate mitochondri...
Published: June, 2018

Abstract: Thyroid hormone receptor β1 (THRB1) and estrogen-related receptor α (ESRRA; also known as ERRα) both play important roles in mitoc... Read more »

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LowCell ChIP kit
Integrative multi-omics analysis of intestinal organoid differentia...
Published: June, 2018

Abstract: Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage... Read more »

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Antibody
Episomal HBV persistence within transcribed host nuclear chromatin ...
Published: June, 2018

Abstract: BACKGROUND: In hepatocyte nuclei, hepatitis B virus (HBV) genomes occur episomally as covalently closed circular DNA (cccDNA). The HBV X protein (H... Read more »

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Antibody Microplex Library Preparation kit
Epigenetic inheritance mediated by coupling of RNAi and histone H3K...
Published: June, 2018

Abstract: Histone post-translational modifications (PTMs) are associated with epigenetic states that form the basis for cell-type-specific gene expression. O... Read more »

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Antibody True MicroChIP kit
Paternal sepsis induces alterations of the sperm methylome and damp...
Published: June, 2018

Abstract: Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune respons... Read more »

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DNA Methylation Profiling (RRBS Service)
Whole-Genome Sequencing of Pharmacogenetic Drug Response in Raciall...
Published: June, 2018

Abstract: RATIONALE: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide. There are significant racial/ethnic differences ... Read more »

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LowCell ChIP kit
A quantitative mass spectrometry-based approach to monitor the dyna...
Published: June, 2018

Abstract: Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering disease mechanisms. To enable t... Read more »

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Antibody
Replication-coupled histone H3.1 deposition determines nucleosome c...
Published: June, 2018

Abstract: Developmental phase transitions are often characterized by changes in the chromatin landscape and heterochromatin reorganization. In Arabidopsis, c... Read more »

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LowCell ChIP kit
Genome-wide rules of nucleosome phasing
Published: June, 2018

Abstract: Regular successions of positioned nucleosomes – phased nucleosome arrays (PNAs) – are predominantly known from transcriptional start si... Read more »

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Microplex Library Preparation kit
Modulation of vitamin D signaling by the pioneer factor CEBPA.
Published: June, 2018

Abstract: The myeloid master regulator CCAAT enhancer-binding protein alpha (CEBPA) is known as a pioneer factor. In this study, we report the CEBPA cistrome... Read more »

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Antibody
27nt-RNAs guide histone variant deposition via 'RNA-induced DNA rep...
Published: June, 2018

Abstract: BACKGROUND: During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby,... Read more »

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Beads
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and F...
Published: June, 2018

Abstract: Synovial sarcoma (SS) is defined by the hallmark SS18-SSX fusion oncoprotein, which renders BAF complexes aberrant in two manners: gain of SSX to t... Read more »

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Antibody
A high-quality genome sequence of Rosa chinensis to elucidate ornam...
Published: June, 2018

Abstract: Rose is the world's most important ornamental plant, with economic, cultural and symbolic value. Roses are cultivated worldwide and sold as garden ... Read more »

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Megaruptor
MeDIP combined with in-solution targeted enrichment followed by NGS...
Published: June, 2018

Abstract: DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invas... Read more »

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iDeal Library Preparation Kit
Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB coop...
Published: June, 2018

Abstract: In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), pro... Read more »

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Antibody
Determination of the presence of 5-methylcytosine in Paramecium tet...
Published: June, 2018

Abstract: 5-methylcytosine DNA methylation regulates gene expression and developmental programming in a broad range of eukaryotes. However, its presence and ... Read more »

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Antibody
SETBP1 induces transcription of a network of development genes by a...
Published: June, 2018

Abstract: SETBP1 variants occur as somatic mutations in several hematological malignancies such as atypical chronic myeloid leukemia and as de novo germline ... Read more »

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Antibody
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedif...
Published: June, 2018

Abstract: To date, it remains largely unclear to what extent chromatin machinery contributes to the susceptibility and progression of complex diseases. Here,... Read more »

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Antibody
DNA Methylation and Regulatory Elements during Chicken Germline Ste...
Published: June, 2018

Abstract: The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell di... Read more »

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MethylCap
Immunity drives regulation in cancer through NF-κB.
Published: June, 2018

Abstract: Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to... Read more »

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Antibody

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