Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

TGFβ promotes widespread enhancer chromatin opening and operates on...
Published: December, 2020

Abstract: The Transforming Growth Factor-β (TGFβ) signaling pathway controls transcription by regulating enhancer activity. How TGFβ-regulated... Read more »

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Antibody CRISPR
PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across ...
Published: December, 2020

Abstract: The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal developmen... Read more »

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Antibody
Efficient hybrid de novo assembly of human genomes with WENGAN.
Published: December, 2020

Abstract: Generating accurate genome assemblies of large, repeat-rich human genomes has proved difficult using only long, error-prone reads, and most human g... Read more »

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Megaruptor
Histone H1 loss drives lymphoma by disrupting 3D chromatin architec...
Published: December, 2020

Abstract: Linker histone H1 proteins bind to nucleosomes and facilitate chromatin compaction, although their biological functions are poorly understood. Muta... Read more »

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Microplex Library Preparation kit True MicroChIP kit
Multi-omic comparison of Alzheimer's variants in human ESC-derivedm...
Published: December, 2020

Abstract: Variations in many genes linked to sporadic Alzheimer's disease (AD) show abundant expression in microglia, but relationships among these genes rem... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones
Chitosan nano-vehicles as biocompatible delivering tools for a newA...
Published: December, 2020

Abstract: A novel anticancer and anti-inflammatory agent based on hybrid curcuminoid-Gboxin analog (FLLL49-GbA) and its macromolecular silver(I) complex (Ag(... Read more »

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Antibody
Kaposi’s Sarcoma-Associated Herpesvirus Processivity Factor, ORF59,...
Published: December, 2020

Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus and the causative agent of potentially fatal malignancies. Lytic replication o... Read more »
Localization and characterization of Citrus centromeres by combinin...
Published: December, 2020

Abstract: KEY MESSAGE: The physical locations of citrus centromere are revealed by combining genetic and immunological assays for the first time and nine cit... Read more »
Incretin drugs effect on epigenetic machinery: New potential therap...
Published: December, 2020

Abstract: The effect of GLP-1R agonists on DNA methylation levels of NF-κB and SOD2 genes in human aortic endothelial cells exposed to high glucose and... Read more »

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Antibody
Derivation of Intermediate Pluripotent Stem Cells Amenable to Primo...
Published: November, 2020

Abstract: Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of pluripotency continuum in vivo. Previous studies have generated a ... Read more »

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Antibody iDeal ChIP-seq Kit for Histones
The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in...
Published: November, 2020

Abstract: The gene CXXC5, encoding a Retinoid-Inducible Nuclear Factor (RINF), is located within a region at 5q31.2 commonly deleted in myelodysplastic syndr... Read more »

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Bioruptor Antibody iDeal ChIP-seq Kit for Transcription Factors
Trans- and cis-acting effects of Firre on epigenetic features of th...
Published: November, 2020

Abstract: Firre encodes a lncRNA involved in nuclear organization. Here, we show that Firre RNA expressed from the active X chromosome maintains histone H3K2... Read more »

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Antibody Microplex Library Preparation kit True MicroChIP kit
ΔNp63 is a pioneer factor that binds inaccessible chromatin and eli...
Published: November, 2020

Abstract: Background: ΔNp63 is a master transcriptional regulator playing critical roles in epidermal development and other cellular processes. Recent ... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors
Complete Genome Sequence of sp. Strain Nx66, Isolated from WatersC...
Published: November, 2020

Abstract: sp. strain Nx66 was isolated from waters contaminated by petrochemical effluents collected in Algeria. Its genome was sequenced using Illumina MiSe... Read more »

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Megaruptor
Genomic profiling of T-cell activation suggests increased sensitivi...
Published: November, 2020

Abstract: T-cell activation is a critical driver of immune responses. The CD28 costimulation is an essential regulator of CD4 T-cell responses, however, its ... Read more »

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iDeal ChIP-seq Kit for Histones
Enhancer hijacking determines extrachromosomal circular MYCN amplic...
Published: November, 2020

Abstract: MYCN amplification drives one in six cases of neuroblastoma. The supernumerary gene copies are commonly found on highly rearranged, extrachromosoma... Read more »

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Antibody
Epigenome-wide association study for pesticide (Permethrin and DEET...
Published: November, 2020

Abstract: BACKGROUND: Permethrin and N,N-diethyl-meta-toluamide (DEET) are the pesticides and insect repellent most commonly used by humans. These pesticides... Read more »

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Antibody
5-Hydroxymethylation highlights the heterogeneity in keratinization...
Published: November, 2020

Abstract: BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide, with human papillomavirus (HPV)-related HNS... Read more »
A genetic variant controls interferon-β gene expression in human my...
Published: November, 2020

Abstract: Interferon β (IFN-β) is a cytokine that induces a global antiviral proteome, and regulates the adaptive immune response to infections and... Read more »

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Bioruptor Microplex Library Preparation kit
Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA L...
Published: November, 2020

Abstract: Herpes simplex virus 1 (HSV-1) induces a profound host shut-off during lytic infection. The virion host shut-off () protein plays a key role in thi... Read more »

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Antibody
Increased H3K4me3 methylation and decreased miR-7113-5p expression ...
Published: November, 2020

Abstract: BACKGROUND: Posttraumatic stress disorder (PTSD) is a psychiatric disorder accompanied by chronic peripheral inflammation. What triggers inflammati... Read more »

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Antibody True MicroChIP kit
A histone H3.3K36M mutation in mice causes an imbalance of histonem...
Published: November, 2020

Abstract: Histone lysine-to-methionine (K-to-M) mutations have been identified as driver mutations in human cancers. Interestingly, these 'oncohistone' mutat... Read more »

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Antibody
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation a...
Published: November, 2020

Abstract: The discovery of H3K27M mutations in pediatric gliomas marked a new chapter in cancer epigenomics. Numerous studies have investigated the effect of... Read more »

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IP-Star Compact iDeal ChIP-seq Kit for Histones
BCG Vaccination Induces Long-Term Functional Reprogramming of Human...
Published: November, 2020

Abstract: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous infections, probably via induction of non-specifi... Read more »

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Antibody
TRF2 Mediates Replication Initiation within Human Telomeres to Prev...
Published: November, 2020

Abstract: The telomeric shelterin protein telomeric repeat-binding factor 2 (TRF2) recruits origin recognition complex (ORC) proteins, the foundational build... Read more »

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Antibody
Macrophage Immune Memory Controls Endometriosis in Mice and Humans.
Published: November, 2020

Abstract: Endometriosis is a frequent, chronic, inflammatory gynecological disease characterized by the presence of ectopic endometrial tissue causing pain a... Read more »

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iDeal ChIP-seq Kit for Histones
MEAF6 is essential for cell proliferation and plays a role in theas...
Published: November, 2020

Abstract: Myst family genes encode lysine acetyltransferases that mainly mediate histone acetylation to control transcription, DNA replication and DNA damage... Read more »

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Antibody
CDK4/6 inhibition reprograms the breast cancer enhancer landscape b...
Published: November, 2020

Abstract: Pharmacologic inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6) were designed to induce cancer cell cycle arrest. Recent studies have suggest... Read more »

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Antibody
ZNF354C is a transcriptional repressor that inhibits endothelialang...
Published: November, 2020

Abstract: Zinc finger proteins (ZNF) are a large group of transcription factors with diverse functions. We recently discovered that endothelial cells harbour... Read more »

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Antibody Beads
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALSCom...
Published: October, 2020

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »

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