Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Methyl-CpG-binding protein 2 mediates antifibrotic effects in scler...
Published: August, 2018

Abstract: OBJECTIVE: Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of met... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
The transcriptional factor ZEB1 represses Syndecan 1 expression in ...
Published: July, 2018

Abstract: Syndecan 1 (SDC-1) is a cell surface proteoglycan with a significant role in cell adhesion, maintaining epithelial integrity. SDC1 expression is in... Read more »

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Antibody
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-select...
Published: July, 2018

Abstract: ABSTACT: Polycomb-mediated repression of gene expression is essential for development, with a pivotal role played by trimethylation of histone H3 l... Read more »

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Antibody
TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Published: July, 2018

Abstract: Testis-specific protein, Y-encoded-like 2 (TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously sh... Read more »

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Antibody
Wnt receptor Frizzled 8 is a target of ERG in prostate cancer
Published: July, 2018

Abstract: Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men. Many molecular changes have been detailed during PCa progression. ... Read more »

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ChIP-qPCR
The transcription factor Lef1 switches partners from β-catenin to S...
Published: July, 2018

Abstract: Skeletal muscle stem cells (MuSCs), also known as satellite cells, persist in adult mammals by entering a state of quiescence (G) during the early ... Read more »

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LowCell ChIP kit
Longitudinal Effects of Developmental Bisphenol A Exposure on Epige...
Published: July, 2018

Abstract: BACKGROUND: Epigenetic machinery plays an important role in genomic imprinting, a developmental process that establishes parent-of-origin-specific ... Read more »
Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2...
Published: July, 2018

Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both ... Read more »

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Antibody
Embryonic germ cell extracts erase imprinted genes and improve the ...
Published: July, 2018

Abstract: Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies hav... Read more »

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MagMeDIP kit
SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylat...
Published: July, 2018

Abstract: Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves... Read more »

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Bioruptor IP-Star Antibody
DNA methylation and genetic degeneration of the Y chromosome in the...
Published: July, 2018

Abstract: BACKGROUND: S. latifolia is a model organism for the study of sex chromosome evolution in plants. Its sex chromosomes include large regions in whic... Read more »
A Somatically Acquired Enhancer of the Androgen Receptor Is a Nonco...
Published: July, 2018

Abstract: Increased androgen receptor (AR) activity drives therapeutic resistance in advanced prostate cancer. The most common resistance mechanism is amplif... Read more »

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Antibody
A LINE1-Nucleolin Partnership Regulates Early Development and ESC I...
Published: July, 2018

Abstract: Transposable elements represent nearly half of mammalian genomes and are generally described as parasites, or "junk DNA." The LINE1 retrotransposon... Read more »

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LowCell ChIP kit
LSD1-ERRα complex requires NRF1 to positively regulate transcriptio...
Published: July, 2018

Abstract: Lysine-specific demethylase 1 (LSD1) exerts dual effects on histone H3, promoting transcriptional repression via Lys4 (H3K4) demethylation or trans... Read more »

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iDeal ChIP-seq Kit for Histones
TRPM7 controls mesenchymal features of breast cancer cells by tensi...
Published: July, 2018

Abstract: Mechanically induced signaling pathways are important drivers of tumor progression. However, if and how mechanical signals affect metastasis or the... Read more »

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Antibody
Enhancer-driven transcriptional regulation is a potential key deter...
Published: June, 2018

Abstract: Obesity is characterized by the excess of body fat leading to impaired health. Abdominal fat is particularly harmful and is associated with cardiov... Read more »

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Microplex Library Preparation kit
An Integrated and Semiautomated Microscaled Approach to Profile Cis...
Published: June, 2018

Abstract: Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory ... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Gene promoter and exon DNA methylation changes in colon cancer deve...
Published: June, 2018

Abstract: BACKGROUND: DNA mutations occur randomly and sporadically in growth-related genes, mostly on cytosines. Demethylation of cytosines may lead to gene... Read more »

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IP-Star MethylCap
Thyroid hormone receptor and ERRα coordinately regulate mitochondri...
Published: June, 2018

Abstract: Thyroid hormone receptor β1 (THRB1) and estrogen-related receptor α (ESRRA; also known as ERRα) both play important roles in mitoc... Read more »

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LowCell ChIP kit
Integrative multi-omics analysis of intestinal organoid differentia...
Published: June, 2018

Abstract: Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage... Read more »

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Antibody
Episomal HBV persistence within transcribed host nuclear chromatin ...
Published: June, 2018

Abstract: BACKGROUND: In hepatocyte nuclei, hepatitis B virus (HBV) genomes occur episomally as covalently closed circular DNA (cccDNA). The HBV X protein (H... Read more »

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Antibody Microplex Library Preparation kit
Epigenetic inheritance mediated by coupling of RNAi and histone H3K...
Published: June, 2018

Abstract: Histone post-translational modifications (PTMs) are associated with epigenetic states that form the basis for cell-type-specific gene expression. O... Read more »

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Antibody True MicroChIP kit
Paternal sepsis induces alterations of the sperm methylome and damp...
Published: June, 2018

Abstract: Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune respons... Read more »

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DNA Methylation Profiling (RRBS Service)
Whole-Genome Sequencing of Pharmacogenetic Drug Response in Raciall...
Published: June, 2018

Abstract: RATIONALE: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide. There are significant racial/ethnic differences ... Read more »

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LowCell ChIP kit
A quantitative mass spectrometry-based approach to monitor the dyna...
Published: June, 2018

Abstract: Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering disease mechanisms. To enable t... Read more »

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Antibody
Replication-coupled histone H3.1 deposition determines nucleosome c...
Published: June, 2018

Abstract: Developmental phase transitions are often characterized by changes in the chromatin landscape and heterochromatin reorganization. In Arabidopsis, c... Read more »

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LowCell ChIP kit
Genome-wide rules of nucleosome phasing
Published: June, 2018

Abstract: Regular successions of positioned nucleosomes – phased nucleosome arrays (PNAs) – are predominantly known from transcriptional start si... Read more »

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Microplex Library Preparation kit
Modulation of vitamin D signaling by the pioneer factor CEBPA.
Published: June, 2018

Abstract: The myeloid master regulator CCAAT enhancer-binding protein alpha (CEBPA) is known as a pioneer factor. In this study, we report the CEBPA cistrome... Read more »

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Antibody
27nt-RNAs guide histone variant deposition via 'RNA-induced DNA rep...
Published: June, 2018

Abstract: BACKGROUND: During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby,... Read more »

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Beads
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and F...
Published: June, 2018

Abstract: Synovial sarcoma (SS) is defined by the hallmark SS18-SSX fusion oncoprotein, which renders BAF complexes aberrant in two manners: gain of SSX to t... Read more »

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Antibody

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