Diagenode

>>>   Click for Diagenode’s approach to COVID-19

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Epigenomic signatures underpin the axonal regenerative ability of d...
Published: October, 2019

Abstract: Axonal injury results in regenerative success or failure, depending on whether the axon lies in the peripheral or the CNS, respectively. The presen... Read more »

Tags
Antibody
Complete Genome Sequence of an Enterohemorrhagic Escherichia coli O...
Published: October, 2019

Abstract: We present the complete genome sequence of an enterohemorrhagic O111:H8 strain. This strain was isolated from a hemolytic-uremic syndrome patient a... Read more »

Tags
Megaruptor
Transcriptional alterations in glioma result primarily from DNA met...
Published: October, 2019

Abstract: In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. H... Read more »

Tags
Antibody
Programmed increases in LXRα induced by paternal alcohol use enhanc...
Published: September, 2019

Abstract: Paternally inherited alterations in epigenetic programming are emerging as relevant factors in numerous disease states, including the growth and me... Read more »

Tags
Bioruptor Plus
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusi...
Published: September, 2019

Abstract: Epigenetic regulators play a critical role in normal and malignant hematopoiesis. Deregulation, including epigenetic deregulation, of the gene clus... Read more »

Tags
iDeal Library Preparation Kit
Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of...
Published: September, 2019

Abstract: During endochondral ossification, the differentiation of proliferating into hypertrophic chondrocytes is a key step determining the pace of bone fo... Read more »

Tags
True MicroChIP kit
Assaying epigenome functions of PRMTs and their substrates.
Published: September, 2019

Abstract: Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein ... Read more »

Tags
Antibody
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediat...
Published: September, 2019

Abstract: Acute myeloid leukemia (AML) is associated with mutations in transcriptional and epigenetic regulator genes impairing myeloid differentiation. The ... Read more »

Tags
Antibody
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acety...
Published: September, 2019

Abstract: Inactivating mutations of the CREBBP and EP300 acetyltransferases are among the most common genetic alterations in diffuse large B cell lymphoma (D... Read more »

Tags
Antibody
Functional analyses of a low-penetrance risk variant rs6702619/1p21...
Published: September, 2019

Abstract: Several studies employed the genome-wide association (GWA) analysis of single-nucleotide polymorphisms (SNPs) to identify susceptibility regions in... Read more »

Tags
Antibody
Relationship between osteoporosis and osteoarthritis based on DNA m...
Published: September, 2019

Abstract: : The aim of this study was to investigate the relationship between osteoporosis and osteoarthritis by analyzing the DNA methylation in osteoporosi... Read more »

Tags
Antibody
Improved double-nicking strategies for COL7A1 editing by homologous...
Published: September, 2019

Abstract: Current gene editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin di... Read more »

Tags
Antibody
Improved Double-Nicking Strategies for COL7A1-Editing by Homologous...
Published: September, 2019

Abstract: Current gene-editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin di... Read more »

Tags
Antibody
Cooperation of cancer drivers with regulatory germline variants sha...
Published: September, 2019

Abstract: Pediatric malignancies including Ewing sarcoma (EwS) feature a paucity of somatic alterations except for pathognomonic driver-mutations that cannot... Read more »

Tags
iDeal ChIP-seq Kit for Transcription Factors
Residual apoptotic activity of a tumorigenic p53 mutant improves ca...
Published: September, 2019

Abstract: Engineered p53 mutant mice are valuable tools for delineating p53 functions in tumor suppression and cancer therapy. Here, we have introduced the R... Read more »

Tags
Microplex Library Preparation kit
β-Glucan-Induced Trained Immunity Protects against Leishmania brazi...
Published: September, 2019

Abstract: American tegumentary leishmaniasis is a vector-borne parasitic disease caused by Leishmania protozoans. Innate immune cells undergo long-term funct... Read more »

Tags
Antibody
Reactivation of super-enhancers by KLF4 in human Head and Neck Squa...
Published: September, 2019

Abstract: Head and neck squamous cell carcinoma (HNSCC) is a disease of significant morbidity and mortality and rarely diagnosed in early stages. Despite ext... Read more »

Tags
Antibody IP-Star Compact
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic...
Published: September, 2019

Abstract: Enzymes that catalyse CpG methylation in DNA, including the DNA methyltransferases 1 (DNMT1), 3A (DNMT3A) and 3B (DNMT3B), are indispensable for ma... Read more »

Tags
IP-Star Compact iDeal ChIP-seq Kit for Histones
Preparation of cfMeDIP-seq libraries for methylome profiling of pla...
Published: August, 2019

Abstract: Circulating cell-free DNA (cfDNA) comprises small DNA fragments derived from normal and tumor tissue that are released into the bloodstream. Recent... Read more »

Tags
MagMeDIP kit Antibody IPure kit
BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-n...
Published: August, 2019

Abstract: Therapeutic strategies aiming to leverage anti-tumor immunity are being intensively investigated as they show promising results in cancer therapy. ... Read more »

Tags
Antibody
Human mitochondrial DNA is extensively methylated in a non-CpG context
Published: August, 2019

Abstract: Mitochondrial dysfunction plays critical roles in cancer development and related therapeutic response; however, exact molecular mechanisms remain u... Read more »

Tags
MagMeDIP kit IP-Star Compact
Long-read sequencing and haplotype linkage analysis enabled preimpl...
Published: August, 2019

Abstract: BACKGROUND: Preimplantation genetic testing (PGT) has already been applied in patients known to carry chromosomal structural variants to improve th... Read more »

Tags
Megaruptor
Nucleome Dynamics during Retinal Development.
Published: August, 2019

Abstract: More than 8,000 genes are turned on or off as progenitor cells produce the 7 classes of retinal cell types during development. Thousands of enhance... Read more »

Tags
Antibody iDeal ChIP-seq Kit for Histones
Silencing of tumor-suppressive NR_023387 in renal cell carcinoma vi...
Published: August, 2019

Abstract: Dysregulation of the epigenetic status of long noncoding RNAs (lncRNAs) has been linked to diverse human diseases including human cancers. However,... Read more »

Tags
Antibody
Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macropha...
Published: August, 2019

Abstract: Macrophage polarization is accompanied by drastic changes in L-arginine metabolism. Two L-arginine catalytic enzymes, iNOS and arginase 1, are well... Read more »

Tags
Antibody
Single-base methylome profiling of the giant kelp Saccharina japoni...
Published: August, 2019

Abstract: Brown algae have convergently evolved plant-like body plans and reproductive cycles, which in plants are controlled by differential DNA methylation... Read more »

Tags
MagMeDIP kit
Novel Interactions between the Human T-Cell Leukemia Virus Type 1 A...
Published: August, 2019

Abstract: The human T-cell leukemia virus type 1 (HTLV-1) regulatory proteins Tax and HBZ play indispensable roles in regulating viral and cellular gene expr... Read more »

Tags
HighCell ChIP kit
The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contribut...
Published: August, 2019

Abstract: Lung cancer is the leading cause of cancer death worldwide, with poor prognosis and a high rate of recurrence despite early surgical removal. Hypox... Read more »

Tags
iDeal ChIP-qPCR ChIP Cross-link Gold
Epitranscriptomic Addition of mC to HIV-1 Transcripts Regulates Vir...
Published: August, 2019

Abstract: How the covalent modification of mRNA ribonucleotides, termed epitranscriptomic modifications, alters mRNA function remains unclear. One issue... Read more »

Tags
Antibody
Human cardiac fibrosis-on-a-chip model recapitulates disease hallma...
Published: August, 2019

Abstract: While interstitial fibrosis plays a significant role in heart failure, our understanding of disease progression in humans is limited. To address th... Read more »

Tags
CATS

       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics