Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2...
Published: July, 2018

Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both ... Read more »

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Antibody
SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylat...
Published: July, 2018

Abstract: Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves... Read more »

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Bioruptor IP-Star Antibody
DNA methylation and genetic degeneration of the Y chromosome in the...
Published: July, 2018

Abstract: BACKGROUND: S. latifolia is a model organism for the study of sex chromosome evolution in plants. Its sex chromosomes include large regions in whic... Read more »
LSD1-ERRα complex requires NRF1 to positively regulate transcriptio...
Published: July, 2018

Abstract: Lysine-specific demethylase 1 (LSD1) exerts dual effects on histone H3, promoting transcriptional repression via Lys4 (H3K4) demethylation or trans... Read more »

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iDeal ChIP-seq Kit for Histones
TRPM7 controls mesenchymal features of breast cancer cells by tensi...
Published: July, 2018

Abstract: Mechanically induced signaling pathways are important drivers of tumor progression. However, if and how mechanical signals affect metastasis or the... Read more »

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Antibody
An Integrated and Semiautomated Microscaled Approach to Profile Cis...
Published: June, 2018

Abstract: Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory ... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Gene promoter and exon DNA methylation changes in colon cancer deve...
Published: June, 2018

Abstract: BACKGROUND: DNA mutations occur randomly and sporadically in growth-related genes, mostly on cytosines. Demethylation of cytosines may lead to gene... Read more »

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IP-Star MethylCap
Integrative multi-omics analysis of intestinal organoid differentia...
Published: June, 2018

Abstract: Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage... Read more »

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Antibody
Paternal sepsis induces alterations of the sperm methylome and damp...
Published: June, 2018

Abstract: Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune respons... Read more »

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DNA Methylation Profiling (RRBS Service)
Whole-Genome Sequencing of Pharmacogenetic Drug Response in Raciall...
Published: June, 2018

Abstract: RATIONALE: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide. There are significant racial/ethnic differences ... Read more »

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LowCell ChIP kit
Replication-coupled histone H3.1 deposition determines nucleosome c...
Published: June, 2018

Abstract: Developmental phase transitions are often characterized by changes in the chromatin landscape and heterochromatin reorganization. In Arabidopsis, c... Read more »

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LowCell ChIP kit
Genome-wide rules of nucleosome phasing
Published: June, 2018

Abstract: Regular successions of positioned nucleosomes – phased nucleosome arrays (PNAs) – are predominantly known from transcriptional start si... Read more »

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Microplex Library Preparation kit
27nt-RNAs guide histone variant deposition via 'RNA-induced DNA rep...
Published: June, 2018

Abstract: BACKGROUND: During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby,... Read more »

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Beads
A high-quality genome sequence of Rosa chinensis to elucidate ornam...
Published: June, 2018

Abstract: Rose is the world's most important ornamental plant, with economic, cultural and symbolic value. Roses are cultivated worldwide and sold as garden ... Read more »

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Megaruptor
MeDIP combined with in-solution targeted enrichment followed by NGS...
Published: June, 2018

Abstract: DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invas... Read more »

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iDeal Library Preparation Kit
Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB coop...
Published: June, 2018

Abstract: In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), pro... Read more »

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Antibody
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedif...
Published: June, 2018

Abstract: To date, it remains largely unclear to what extent chromatin machinery contributes to the susceptibility and progression of complex diseases. Here,... Read more »

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Antibody
DNA Methylation and Regulatory Elements during Chicken Germline Ste...
Published: June, 2018

Abstract: The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell di... Read more »

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MethylCap
The reference epigenome and regulatory chromatin landscape of chron...
Published: June, 2018

Abstract: Chronic lymphocytic leukemia (CLL) is a frequent hematological neoplasm in which underlying epigenetic alterations are only partially understood. H... Read more »

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Antibody
Epigenetic regulation of vascular NADPH oxidase expression and reac...
Published: June, 2018

Abstract: Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in... Read more »

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Antibody
Involvement of Epigenetic Modifications of GABAergic Interneurons i...
Published: June, 2018

Abstract: Background: Prenatal stress is considered a risk factor for anxiety disorder. Downregulation in the expression of GABAergic gene, that is, glutamic... Read more »

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MeDIP kit
Increased H3K9 methylation and impaired expression of Protocadherin...
Published: June, 2018

Abstract: Kleefstra syndrome, a disease with intellectual disability, autism spectrum disorders and other developmental defects is caused in humans by haploi... Read more »

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Antibody
Histone H3 lysine 36 methyltransferase mobilizes NER factors to reg...
Published: June, 2018

Abstract: The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA d... Read more »

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Antibody
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: June, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora of functio... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense...
Published: June, 2018

Abstract: BACKGROUND: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide m... Read more »
An improved assembly and annotation of the melon (Cucumis melo L.) ...
Published: May, 2018

Abstract: We report an improved assembly (v3.6.1) of the melon (Cucumis melo L.) genome and a new genome annotation (v4.0). The optical mapping approach allo... Read more »

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IPure kit IP-Star Compact
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: May, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Antibody
Distinct epigenetic landscapes underlie the pathobiology of pancrea...
Published: May, 2018

Abstract: Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although... Read more »

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Antibody
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018

Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »

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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Insulin promoter in human pancreatic β cells contacts diabetes susc...
Published: May, 2018

Abstract: Both type 1 and type 2 diabetes involve a complex interplay between genetic, epigenetic, and environmental factors. Our laboratory has been interes... Read more »

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