Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Isl1 mediates mesenchymal expansion in the developing external geni...
Published: January, 2018

Abstract: Genital malformations are among the most common human birth defects, and both genetic and environmental factors can contribute to these malformatio... Read more »
BRACHYURY directs histone acetylation to target loci during mesoder...
Published: January, 2018

Abstract: T-box transcription factors play essential roles in multiple aspects of vertebrate development. Here, we show that cooperative function of BRACHYUR... Read more »

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Antibody
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: December, 2017

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Bioruptor ChIP-seq
(Po)STAC (Polycistronic SunTAg modified CRISPR) enables live-cell a...
Published: December, 2017

Abstract: CRISPR/dCas9-based labeling has allowed direct visualization of genomic regions in living cells. However, poor labeling efficiency and signal-to-ba... Read more »

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Antibody
Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest ...
Published: December, 2017

Abstract: Cockayne syndrome (CS) is caused by mutations in CSA and CSB. The CSA and CSB proteins have been linked to both promoting transcription-coupled rep... Read more »

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Antibody
The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome...
Published: December, 2017

Abstract: Therapeutic intervention is an important need in ameliorating the severe consequences of Rett Syndrome (RTT), a neurological disorder caused by mut... Read more »

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Antibody
Repeated methamphetamine and modafinil induce differential cognitiv...
Published: December, 2017

Abstract: Methamphetamine (METH) and modafinil are psychostimulants with different long-term cognitive profiles: METH is addictive and leads to cogniti... Read more »

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DNA shearing Bioruptor
Oestrogen Receptor-α binds the FOXP3 promoter and modulates regulat...
Published: December, 2017

Abstract: Oestrogen controls Foxp3 expression in regulatory T cells (Treg cells) via a mechanism thought to involve oestrogen receptor alpha (ERα), but... Read more »

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Antibody
Dual SIRT1 expression patterns strongly suggests its bivalent role ...
Published: December, 2017

Abstract: Breast cancer is the most common cancer in women, and the leading cause of cancer death in women worldwide. SIRT1 (silent mating type information r... Read more »

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Antibody
Functional dissection of Drosophila melanogaster SUUR protein influ...
Published: December, 2017

Abstract: Background In eukaryotes, heterochromatin replicates late in S phase of the cell cycle and contains specific covalent modifications of histones.... Read more »

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Microplex Library Preparation kit True MicroChIP kit
Super enhancer associated RAI14 is a new potential biomarker in lun...
Published: December, 2017

Abstract: Tyrosine kinase inhibitors (TKIs) are widely used to treat lung adenocarcinoma patients with EGFR mutations or ALK-fusions. However, patients with ... Read more »

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Bioruptor
Optimization of CRISPR/Cas9 genome editing for loss-of-function in ...
Published: December, 2017

Abstract: The advent of CRISPR/Cas9 has made genome editing possible in virtually any organism, including those not previously amenable to genetic manipulati... Read more »

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Antibody
Single-cell absolute contact probability detection reveals chromoso...
Published: November, 2017

Abstract: At the kilo- to megabase pair scales, eukaryotic genomes are partitioned into self-interacting modules or topologically associated domains (TADs) t... Read more »

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Antibody
The histone code reader Spin1 controls skeletal muscle development
Published: November, 2017

Abstract: While several studies correlated increased expression of the histone code reader Spin1 with tumor formation or growth, little is known about physio... Read more »

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Antibody IP-Star Compact
DNA methylation signatures follow preformed chromatin compartments ...
Published: November, 2017

Abstract: Storage of chromatin in restricted nuclear space requires dense packing while ensuring DNA accessibility. Thus, different layers of chromatin organ... Read more »

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Antibody
ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cel...
Published: November, 2017

Abstract: The protein p27Kip1 (p27), a member of the Cip-Kip family of cyclin-dependent kinase inhibitors, is involved in tumorigenesis and a correlation bet... Read more »

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IPure kit
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesen...
Published: November, 2017

Abstract: RATIONALE: Human cardiac mesenchymal cells (CMSCs) are a therapeutically relevant primary cell population. Diabetes mellitus compromises CMSC fu... Read more »
FBXO32 promotes microenvironment underlying epithelial-mesenchymal ...
Published: November, 2017

Abstract: The set of events that convert adherent epithelial cells into migratory cells are collectively known as epithelial-mesenchymal transition (EMT). EM... Read more »

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Antibody
In Situ Fixation Redefines Quiescence and Early Activation of Skele...
Published: November, 2017

Abstract: Summary State of the art techniques have been developed to isolate and analyze cells from various tissues, aiming to capture their in viv... Read more »

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Antibody Premium RRBS Kit
PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumor...
Published: November, 2017

Abstract: In NSCLC alterations in PDGF receptors are markers of worst prognosis and efficient targeting of these receptors is yet to be achieved. In this stu... Read more »

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IPure kit
Data on novel DNA methylation changes induced by valproic acid in h...
Published: November, 2017

Abstract: Valproic acid (VPA) is a widely prescribed antiepileptic drug in the world. Despite its pharmacological importance, it may cause liver toxicity and... Read more »

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MagMeDIP kit IPure kit
GATA2/3-TFAP2A/C transcription factor network couples human pluripo...
Published: November, 2017

Abstract: To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophectoderm character... Read more »

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Antibody
5-Methylcytosine RNA Methylation in Arabidopsis Thaliana
Published: November, 2017

Abstract: 5-Methylcytosine (m5C) is a well-characterized DNA modification, and is also predominantly reported in abundant non-coding RNAs in both prokaryotes... Read more »

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Antibody
An endosiRNA-Based Repression Mechanism Counteracts Transposon Acti...
Published: November, 2017

Abstract: Erasure of DNA methylation and repressive chromatin marks in the mammalian germline leads to risk of transcriptional activation of transposable ele... Read more »

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Microplex Library Preparation kit
Transcription Factor YY1 Modulates Lung Cancer Progression by Activ...
Published: November, 2017

Abstract: Lung cancer is the leading cause of cancer-related death worldwide. Despite the advancement in surgery and chemotherapy, the prognosis of patients ... Read more »
Epigenetic control of epilepsy target genes contributes to a cellul...
Published: October, 2017

Abstract: Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable l... Read more »
Drug-tunable multidimensional synthetic gene control using inducibl...
Published: October, 2017

Abstract: The nuclease-deactivated variant of CRISPR-Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA sequen... Read more »

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Antibody
Saliva as a Blood Alternative for Genome-Wide DNA Methylation Profi...
Published: October, 2017

Abstract: Background: Interrogation of DNA methylation profiles hold promise for improved diagnostics, as well as the delineation of the aetiology for common... Read more »

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IP-Star Compact
Alterations in the placental methylome with maternal obesity and ev...
Published: October, 2017

Abstract: The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complicat... Read more »

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Antibody

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