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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Traditional Chinese Medicine Luo Tong Formula attenuates retinal in...
Published: July, 2025
Abstract: Background: Diabetic retinopathy (DR) is a leading cause of blindness in the adult population. Luo-Tong Formula (LTF), a traditional Chinese medici... Read more »
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Antibody
Liebenberg syndrome severity arises from variations in Pitx1 locus ...
Published: July, 2025
Abstract: Enhancer hijacking, a common cause of gene misregulation linked to disease, occurs when non-matching enhancers and promoters interact ectopical... Read more »
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Antibody
Dissecting the epigenetic regulation of the fetal hemoglobin genes ...
Published: July, 2025
Abstract: Beta-hemoglobinopathies are severe genetic diseases caused by mutations affecting the production of the adult β-globin chain. The clinical... Read more »
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Antibody
TP53 missense-specific transcriptional plasticity drives resistance...
Published: July, 2025
Abstract: In ~70% of patients with pancreatic ductal adenocarcinoma, the TP53 gene acquires gain-of-function (GOF) mutations leading to rapid dis... Read more »
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Microplex Library Preparation kit
TEAD-targeting small molecules induce a cofactor switch to regulate...
Published: July, 2025
Abstract: Abstract TEAD proteins are the main transcriptional effectors of the Hippo signaling pathway and a clinical-stage pharmacological target in oncolo... Read more »
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Chromatin Profiling (ChIP-seq) Services
Spatial profiling of chromatin accessibility in formalin-fixed para...
Published: July, 2025
Abstract: Formalin-fixed paraffin-embedded (FFPE) samples represent a vast, untapped resource for epigenomic research, yet molecular tools for deep analysi... Read more »
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Tagmentase
Distinguishing benign from pathogenic duplications involving GPR101...
Published: June, 2025
Abstract: Background: Structural variants (SVs) that disrupt topologically associating domains (TADs) can cause disease by rewiring enhancer-promoter inte... Read more »
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ATAC-seq
Constitutive expression of the transcriptional co-activator IκBζ pr...
Published: June, 2025
Abstract: IκBζ, a rather unknown co-regulator of NF-κB, can either activate or repress a subset of NF-κB target genes. While its r... Read more »
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Antibody
Landscape and regulation of mRNA translation in the early C. elegan...
Published: June, 2025
Abstract: Animal embryos rely on regulated translation of maternally deposited mRNAs to drive early development. Using low-input ribosome profiling combine... Read more »
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D-Plex small RNA-seq
Quantitative measurement of phenotype dynamics during cancer drug r...
Published: June, 2025
Abstract: Cancer treatment frequently fails due to the evolution of drug-resistant cell phenotypes driven by genetic or non-genetic changes. The origin... Read more »
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Tagmentase
Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells
Published: June, 2025
Abstract: Iron is an irreplaceable co-factor for metabolism. Iron deficiency affects >1 billion people and decreased iron availability impairs immunit... Read more »
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Antibody
Extrusion fountains are restricted by WAPL-dependent cohesin releas...
Published: June, 2025
Abstract: Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-eff... Read more »
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Antibody
RSK1-driven TRIM28/E2F1 feedback loop promotes castration-resistant...
Published: June, 2025
Abstract: Castration-resistant prostate cancer (CRPC) marks the advanced and lethal stage of prostate cancer (PCa). TRIM28, also known as KAP1, is a transc... Read more »
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Tagmentase
Polycomb Repressive Complex 2 facilitates the transition from heter...
Published: June, 2025
Abstract: The seed-to-seedling transition represents a key developmental and metabolic switch in plants. Catabolism of seed storage reserves fuels germinat... Read more »
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IPure kit
CRAMP1 drives linker histone expression to enable Polycomb repression
Published: June, 2025
Abstract: In contrast to the well-understood role of core histones in DNA packaging, the function of the linker histone (H1) remains enigmatic. Challenging... Read more »
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ATAC-seq
Neuronal migration induces DNA damage in developing brain
Published: June, 2025
Abstract: Migratory cells tend to have soft nuclei that deform and penetrate narrow spaces1,2. Extensive nuclear deformation during migration can cause nuc... Read more »
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Tagmentase
Impact of polyethylene terephthalate nanoplastics (PET) on fibrobla...
Published: June, 2025
Abstract: Plastic pollution has become a major environmental and public health issue due to rising global production. Nanoplastics (NPs) are especially con... Read more »
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Bioruptor
A spatially organized Cd24a+/ Pax9+ stem cell core governs postnata...
Published: June, 2025
Abstract: Mineralized tissues are fundamental in mechanical support and protection in vertebrates. Their formation by progenitor cells during development... Read more »
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Antibody
Temporal and spatial niche partitioning in a retrotransposon commun...
Published: June, 2025
Abstract: Transposable elements (TEs) are genetic parasites that can potentially threaten the stability of the genomes they colonize. Nonetheless, TEs pe... Read more »
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ATAC-seq
The impact of Fulvestrant on Estrogen Receptor-Driven Chromatin Dyn...
Published: June, 2025
Abstract: Epigenetic dysregulations are linked to various diseases, including cancer. Among them, breast cancer is the second leading cause of cancer-related... Read more »
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CUT&Tag
Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: ...
Published: June, 2025
Abstract: Borrelia burgdorferi, a tick-vectored spirochete bacteria best known for causing Lyme disease, has been found to induce physiological and behav... Read more »
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MagMeDIP kit Antibody
Coupling Immunoprecipitation with Multiplexed Digital PCR for Cell-...
Published: June, 2025
Abstract: Colorectal cancer (CRC) remains a major global health challenge, with an increasing incidence of early-onset cases among young adults. Targeted... Read more »
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MagMeDIP kit IPure kit
Androgen receptor-mediated assisted loading of the glucocorticoid r...
Published: June, 2025
Abstract: Steroid receptors are involved in a wide array of crosstalk mechanisms that regulate diverse biological processes, with significant implication... Read more »
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Tagmentase
Charting the regulatory landscape of TP53 on transposable elements ...
Published: June, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
ATAC-seq in Emerging Model Organisms: Challenges and Strategies
Published: June, 2025
Abstract: The Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) is a versatile and widely utilized method for identifying potential regul... Read more »
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Tagmentase
CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
Published: May, 2025
Abstract: The SWI/SNF (or BAF) complex is an essential chromatin remodeler, which is frequently mutated in cancer and neurodevelopmental disorders. These are... Read more »
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Tagmentase
Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion ...
Published: May, 2025
Abstract: Nucleoporin 98 (NUP98) fusion oncoproteins are strong drivers of pediatric acute myeloid leukemia (AML) with poor prognosis. Here we show that ... Read more »
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CUT&Tag
Spatial epigenomic niches underlie glioblastoma cell state plasticity
Published: May, 2025
Abstract: IDH-wildtype glioblastoma (GBM) is an aggressive brain tumor with poor survival and few therapeutic options. Transcriptionally-defined cell state... Read more »
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Tagmentase
Charting the regulatory landscape of TP53 on transposable elements ...
Published: May, 2025
Abstract: The relationship between TP53 and transposable elements (TEs) has been obscure. Given the important role of TEs in oncogenesis, a comprehensive pro... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Cervicovaginal microbiome alters transcriptomic and epigenomic sign...
Published: May, 2025
Abstract: Background The cervicovaginal microbiome plays a critical role in women's health, with microbial communities dominated by Lactobacillus ... Read more »
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ATAC-seq

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