Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The effect of Jun dimerization on neurite outgrowth and motif binding.
Published: August, 2018

Abstract: Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known ... Read more »

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ChIP-qPCR
TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Published: July, 2018

Abstract: Testis-specific protein, Y-encoded-like 2 (TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously sh... Read more »

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Antibody
Wnt receptor Frizzled 8 is a target of ERG in prostate cancer
Published: July, 2018

Abstract: Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men. Many molecular changes have been detailed during PCa progression. ... Read more »

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ChIP-qPCR
SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylat...
Published: July, 2018

Abstract: Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves... Read more »

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Bioruptor IP-Star Antibody
TRPM7 controls mesenchymal features of breast cancer cells by tensi...
Published: July, 2018

Abstract: Mechanically induced signaling pathways are important drivers of tumor progression. However, if and how mechanical signals affect metastasis or the... Read more »

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Antibody
An Integrated and Semiautomated Microscaled Approach to Profile Cis...
Published: June, 2018

Abstract: Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory ... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Paternal sepsis induces alterations of the sperm methylome and damp...
Published: June, 2018

Abstract: Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune respons... Read more »

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DNA Methylation Profiling (RRBS Service)
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedif...
Published: June, 2018

Abstract: To date, it remains largely unclear to what extent chromatin machinery contributes to the susceptibility and progression of complex diseases. Here,... Read more »

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Antibody
The reference epigenome and regulatory chromatin landscape of chron...
Published: June, 2018

Abstract: Chronic lymphocytic leukemia (CLL) is a frequent hematological neoplasm in which underlying epigenetic alterations are only partially understood. H... Read more »

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Antibody
Epigenetic regulation of vascular NADPH oxidase expression and reac...
Published: June, 2018

Abstract: Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in... Read more »

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Antibody
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: May, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Antibody
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018

Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »

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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Functional interplay between E2F7 and ribosomal rRNA gene transcrip...
Published: May, 2018

Abstract: A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. ... Read more »

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Bioruptor
Local adaptation and ecological differentiation under selection, mi...
Published: May, 2018

Abstract: How the balance between selection, migration and drift influences the evolution of local adaptation has been under intense theoretical scrutiny. Ye... Read more »

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Bioruptor
The chromatin remodeling factor SPOC1 acts as a cellular restricti...
Published: May, 2018

Abstract: The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA dam... Read more »

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Bioruptor Bioruptor Plus
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Nuclear fate of yeast snoRNA is determined by co-transcriptional Rn...
Published: May, 2018

Abstract: Small nucleolar RNA (snoRNA) are conserved and essential non-coding RNA that are transcribed by RNA Polymerase II (Pol II). Two snoRNA classes, for... Read more »

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Bioruptor
The Ftx Noncoding Locus Controls X Chromosome Inactivation Independ...
Published: May, 2018

Abstract: Accumulation of the Xist long noncoding RNA (lncRNA) on one X chromosome is the trigger for X chromosome inactivation (XCI) in female mammals.... Read more »

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Antibody
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Mainta...
Published: May, 2018

Abstract: Hox genes modulate the properties of hematopoietic stem cells (HSCs) and reacquired Hox expression in progenitors contributes to leukemogenesis. He... Read more »

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True MicroChIP kit
SUN2 Modulates HIV-1 Infection and Latency through Association with...
Published: May, 2018

Abstract: The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV gen... Read more »

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Bioruptor
Viral targeting of TFIIB impairs de novo polymerase II recruitment ...
Published: April, 2018

Abstract: Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regula... Read more »

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Bioruptor Bioruptor Plus
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: April, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Bioruptor Bioruptor Plus
Generation of a PAX6 knockout glioblastoma cell line with changes i...
Published: April, 2018

Abstract: The transcription factor PAX6 is expressed in various cancers. In anaplastic astrocytic glioma, PAX6 expression is inversely related to tumor gra... Read more »

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Bioruptor Bioruptor Plus
MYCN acts as a direct co-regulator of p53 in MYCN amplified neurobl...
Published: April, 2018

Abstract: The MYC oncogenes and p53 have opposing yet interrelated roles in normal development and tumorigenesis. How MYCN expression alters the biology and ... Read more »

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Bioruptor
HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hema...
Published: April, 2018

Abstract: The first hematopoietic stem and progenitor cells are generated during development from hemogenic endothelium (HE) through trans-differentiation. T... Read more »

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HighCell ChIP kit Microplex Library Preparation kit
Molecular Signatures of Regression of the Canine Transmissible Vene...
Published: April, 2018

Abstract: The canine transmissible venereal tumor (CTVT) is a clonally transmissible cancer that regresses spontaneously or after treatment with vincristine,... Read more »

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MagMeDIP kit Antibody IP-Star Compact
Phylogenomic evidence for a recent and rapid radiation of lizards i...
Published: March, 2018

Abstract: Rapid evolutionary radiations are difficult to resolve because divergence events are nearly synchronous and gene flow among nascent species can be ... Read more »
Application of next-generation sequencing to characterize novel mut...
Published: March, 2018

Abstract: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of H. pylori eradication. Although the molecular me... Read more »
Effects of developmental lead exposure on the hippocampal methylome...
Published: March, 2018

Abstract: Developmental lead (Pb) exposure results in persistent cognitive/behavioral impairments as well as an elevated risk for developing a variety of dis... Read more »

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IP-Star Compact

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