Epigenomics Profiling Services

Chromatin Profiling Services

Chromatin consists of DNA, histones and non-histone proteins. Understanding the roles of histones and transcription factors is critical in understanding the regulation of gene expression.

Using ChIP-seq analysis, it is possible to profile histone modifications and transcription factor binding genome-wide to elucidate control of gene expression in disease or in response to a drug treatment. Diagenode’s Epigenomic Profiling Services offer a wide variety of chromatin analysis options through ChIP-seq and ATAC-seq.

ATAC-seq: open chromatin regions

Study genome-wide chromatin accessibility. Identify open chromatin sites and active regulatory elements such as promoter, enhancers, and insulators.

Nucleosome positioning

ChIP-seq histone modifications

Post-translational modification of histones is implicated in the regulation of gene expression, necessitating the study of regulatory elements and their interacting proteins like active promoter and enhancer analysis. Profile genome-wide histone modifications by ChIP-seq analysis to understand transcriptional regulation

Active promoter profiling: H3K4me3 enrichment
Inactive promoter profiling: H3K27me3 enrichment
Enhancer profiling: H3K4me1 and H3K27ac enrichment in regulatory regions
Active gene body: H3K36me3

ChIP-seq Transcription Factors

Explore the effects of transcription factor binding through ChIP-seq analysis of a multitude of TFs including:

CTCF: transcriptional repressor and insulator activity
p300/CBP: histone acetyltransferase
Pol II, p53, and more
Epigenetic writers, readers, erasers
Nuclear receptors
Tumor suppressor genes

Products

Cat. No.	Product	Format
G02060000	ATAC-seq service (Assay for Transposase-Accessible Chromatin) ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) allows for assessing genome-wide chromatin accessibility. The technology is based on t...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02010000	ChIP-seq Profiling Service Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a powerful method allowing the genome-wide identification of DNA binding sites for protein...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02100000	Bioinformatics Data Mining Service New! Data mining using machine learning (AI) for unique epigenetic data insights Watch the webinar to gain insights on how data mining can be applied ...	Custom	Get a quote You are about to request a quote for Bioinformatics Data Mining Service. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Comment ×

Events

Long-Read Sequencing Meeting 2024
Uppsala, Sweden
Oct 21-Oct 23, 2024
NextGen Omics 2024
London, UK
Oct 23-Oct 25, 2024
FEBS 2024
Budapest, Hungary
Oct 28-Oct 31, 2024
5th Danube Conference on Epigenetics
Budapest, Hungary
Oct 28-Oct 31, 2024

See all events

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