Chromatin consists of DNA, histones and non-histone proteins.
Using ChIP-seq analysis, it is possible to profile histone modifications and transcription factor binding genome-wide to understand the regulation of gene expression in disease or in response to a drug treatment. Diagenode’s Epigenomic Profiling Services offer a wide variety of chromatin analysis options through ChIP-seq and ATAC-seq.
Study genome-wide chromatin accessibility. Identify open chromatin sites and active regulatory elements such as promoter, enhancers, and insulators.
Post-translational modification of histones is implicated in the regulation of gene expression, necessitating the study of regulatory elements and their interacting proteins like active promoter and enhancer analysis. Profile genome-wide histone modifications by ChIP-seq analysis to understand transcriptional regulation
Explore the effects of transcription factor binding through ChIP-seq analysis of a multitude of TFs including:
ATAC-seq service (Assay for Transposase-Accessible Chromatin)
ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) allows for assessing genome-wide chromatin accessibility. The technology is based on t...
ChIP-seq/ChIP-qPCR Profiling service
What we give to you - ChIP-sequencing and ChIP-qPCR analysis Integrative or individual analyses for chromatin with ENCODE standards End-to-end wet lab se...