RNA-seq Profiling Services

Our Epigenomics Profiling Services assure the sample preparation expertise and quality data that you seek. Our RNA sequencing service uses next-generation sequencing (NGS) to uncover the presence and quantity of RNA for gene expression profiling across the transcriptome. Diagenode specializes in generating RNA-seq libraries which is optimal for low or degraded inputs including those from liquid biopsies, FFPE, exosomes, serum, or plasma.

Current RNA-seq offerings

Small non-coding RNA including miRNA

• Post-transcriptional regulation of gene expression
• Novel transcripts and differentially-expressed small RNAs
• miRNAs involved in regulation of onco- and tumor-suppressor gene expression
• Differential miRNA expression

mRNA analysis

• Protein-coding RNA with specific poly A selection
• Cancer-related mRNA signatures
• Aberrant mRNA translation in cancer pathogenesis
• Gene expression profiling and identification of differentially expressed genes (DEG)
• Epigenetic mechanism of gene expression (transcriptome plus H3K36me3 and H3K4me3 marks)
• Functional annotation of coding genes

Long non-coding RNA and whole transcriptome

• Analysis of whole transcriptome and RNAs larger than 200nt with optional rRNA depletion
• Non-protein coding RNAs involved in chromatin remodeling & transcriptional/post-transcriptional regulation