Epigenomics Profiling Services

DNA Methylation Profiling Services

The pattern of DNA methylation and histone modiﬁcation(s) plays an essential role in maintaining cellular function. Abnormal DNA methylation – hypermethylation and hypomethylation - can result in adverse outcomes such as cancer or other disease. The quantification of 5-mC through genome-wide DNA methylation analysis can provide information for detection and prognosis of disease. Our DNA methylation analysis services include numerous bisulfite sequencing options for targeted or whole genome DNA methylation analysis across any species.

Infinium MethylationEPIC Array Service

The Infinium MethylationEpic Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina^® technology. It allows to quantitatively detect the total methylation level of over 850,000 CpG positions throughout the human genome at single nucleotide resolution.

Cost-effective with rapid turnaround time
Over 850,000 CpGs detected in human samples at single nucleotide resolution
Quantitative interrogation of CpG, non-CpG, and CHH sites
Differentially methylated site analysis
Available for 5hmC profiling

Reduced representation bisulfite sequencing (RRBS)

RRBS provides a powerful method to efficiently analyze DNA methylation at the single nucleotide level without the higher costs associated with whole genome bisulfite sequencing. By cutting the genome using the restriction MspI enzyme (CCGG target sites) followed by size selection, DNA is enriched to represent CpG-rich regions (including CpG islands), in which DNA methylation marks are typically found. Thus, RRBS provides a cost-effective method for analyzing DNA methylation by reducing the part of the genome that actually needs to be sequenced and focusing on relevant CpG islands.

CpG rich region (5-mC): single nucleotide resolution
Epigenetic biomarker discovery
Methylation patterns of CpG rich regions across the genome
Covers up to 4M CpG sites in Human

Whole genome bisulfite sequencing (WGBS)

WGBS is designed to prepare single and paired-end bisulfite converted DNA libraries for sequencing using Illumina^® platforms. It has also been validated for bisulfite-converted library preparation from ChIP-derived samples in order to perform ChIP-Bis-Sequencing. Genome-wide bisulfite sequencing is suitable for studying DNA methylation sites and their role in gene regulation

Genome-wide 5-mC: single nucleotide resolution
Epigenetic biomarker discovery
Methylation patterns of CpG, CHG, and CHH regions across the genome
Epigenome-wide association studies (EWAS)

MeDIP/hMeDIP-seq

Targeted DNA methylation analysis

Products

Cat. No.	Product	Format
G02090004	Infinium MethylationEPIC and Hydroxymethylation oxEPIC Array Service The Infinium MethylationEPIC & Hydroxymethylation oxEPIC Array utilizes a genome-wide DNA methylation analysis technique based on selective oxidat...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02090000	Infinium MethylationEPIC Array Service The Infinium MethylationEPIC Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology. It allow...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02100000	Bioinformatics Data Mining Service New! Data mining using machine learning (AI) for unique epigenetic data insights Watch the webinar to gain insights on how data mining can be applied ...	Custom	Get a quote You are about to request a quote for Bioinformatics Data Mining Service. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Comment ×
G02020000	DNA Methylation Profiling (RRBS Service) *Offer valid only until Agust 31, 2020 for a minimum of 10 samples. Samples must be provided in increments of 10. Alignment to reference gen...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02050000	MeDIP-seq service (Methylated DNA IP Sequencing) Methylated DNA immunoprecipitation sequencing (MeDIP-Seq) is used to study 5-mC genome-wide. In this assay, specific antibodies against 5-mC are used to capt...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02070000	Targeted DNA methylation service Targeted DNA methylation analysis allows for the quantitative study of cytosine methylation at known and precise locations throughout the genome. Depending o...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02040000	WGBS service (Whole Genome Bisulfite Sequencing) Whole-genome bisulfite sequencing (WGBS) is the most comprehensive next generation sequencing for DNA methylation profiling, allowing single-base resol...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP/hMeDIP-seq Targeted DNA methylation analysis Infinium EPIC Array RNA-seq Bioinformatics Data mining Single-Cell ATAC-seq Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×

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