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Epigenomics Profiling Services

DNA Methylation Profiling Services

DNA-methylation -Diagenode

The pattern of DNA methylation and histone modification(s) plays an essential role in maintaining cellular function. Abnormal DNA methylation – hypermethylation and hypomethylation - can result in adverse outcomes such as cancer or other disease. The quantification of 5-mC through genome-wide DNA methylation analysis can provide information for detection and prognosis of disease. Our DNA methylation analysis services include numerous bisulfite sequencing options for targeted or whole genome DNA methylation analysis across any species.

Our Epigenomics Profiling Services helps you to study DNA methylation (5-mC) and methylation variants (5-hmC). Our experienced scientists will guide you to the best solution according to your needs, depending on whether you want to analyze DNA methylation at genome-wide or gene specific scales. They will process the arrays or generate meaningful libraries for DNA sequencing and deliver high quality data. Our bioinformatic experts will closely work with you to provide standard and customized analysis with comprehensive publication-ready figures.

Infinium MethylationEPIC Array Service

  • Cost-effective solution with rapid turnaround time
  • Over 850,000 CpGs detected in human samples at single nucleotide resolution
  • Quantitative interrogation of CpG, non-CpG, and CHH sites
  • Differentially methylated site analysis using bioinformatics tools
  • Available for 5hmC profiling

Reduced Representation Bisulfite Sequencing (RRBS) Service

  • Robust and cost-effective solution with confidence in results
  • Over 4 million CpGs detected in human samples at single nucleotide resolution
  • Detection of methylation patterns in CpG-rich regions across the genome including promoters and CpG islands
  • Differentially methylated site analysis using bioinformatics tools
  • Suitable for epigenetic biomarker discovery

Whole Genome Bisulfite Sequencing (WGBS) Service

  • Very powerful solution for genome-wide biomarker discovery
  • Evaluation of methylation status of nearly every CpG sites of the entire genome at single-base resolution
  • Detection of global methylation patterns including in low-CpG-density regions and outside of CpG islands
  • Identification of regions or even loci with differential methylation between groups using bioinformatics tools

MeDIP/hMeDIP-seq

Targeted DNA methylation analysis


Products

Cat. No.ProductFormatPrice
G02090004 Infinium MethylationEPIC and Hydroxymethylation oxEPIC Array Service
The Infinium MethylationEPIC & Hydroxymethylation oxEPIC Array utilizes a genome-wide DNA methylation analysis technique based on selective oxidat...
G02090000 Infinium MethylationEPIC Array Service
The Infinium MethylationEPIC Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology. It allows to q...
G02100000 Bioinformatics Data Mining Service
New! Data mining using machine learning (AI) for unique epigenetic data insights Watch the webinar to gain insights on how data mining can be applied ...
Custom
G02050000 MeDIP-seq service (Methylated DNA IP Sequencing)
Methylated DNA immunoprecipitation sequencing (MeDIP-Seq) is used to study 5-mC genome-wide. In this assay, specific antibodies against 5-mC are used to capt...
G02020000 RRBS Service (Reduced Representation Bisulfite Sequencing)
Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis at the single nucleotide level in any vertebrate specie...
G02070000 Targeted DNA methylation service
Targeted DNA methylation analysis allows for the quantitative study of cytosine methylation at known and precise locations throughout the genome. Depending o...
G02040000 WGBS Service (Whole Genome Bisulfite Sequencing)
Whole-genome bisulfite sequencing (WGBS) is the most comprehensive next generation sequencing  for DNA methylation profiling, evaluating methylation sta...

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