The pattern of DNA methylation and histone modiﬁcation(s) plays an essential role in maintaining cellular function. Abnormal DNA methylation – hypermethylation and hypomethylation - can result in adverse outcomes such as cancer or other disease. The quantification of 5-mC through genome-wide DNA methylation analysis can provide information for detection and prognosis of disease. Our DNA methylation analysis services include numerous bisulfite sequencing options for targeted or whole genome DNA methylation analysis across any species.
Our Epigenomics Profiling Services helps you study DNA methylation (5mC) and methylation variants (5hmC). Our experienced scientists will guide you to the best solution according to your needs, depending on whether you want to analyze DNA methylation at genome-wide or gene specific scales. They will process the arrays or generate meaningful libraries for DNA sequencing and deliver high quality data. Our bioinformatic experts will closely work with you to provide standard and customized analysis with comprehensive publication-ready figures.
Cost-Effective Genome Wide DNA Methylation Analysis using Twist Hybrid-Capture Methylome Panel
Infinium MethylationEPIC Array Service
The Infinium MethylationEPIC Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology. It allows ...
RRBS Service (Reduced Representation Bisulfite Sequencing)
Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis at the single nucleotide level in any vertebrate specie...
WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) Service
Whole-genome bisulfite sequencing (WGBS) and Enzymatic Methylation (EM-seq) are the methods of choice for obtaining a comprehensive DNA methylation profiling...
Bioinformatics Data Mining Service
New! Data mining using machine learning (AI) for unique epigenetic data insights Watch the webinar to gain insights on how data mining can be applied ...
Human Methylome Service
NEW! The Human Methylome is a Next-Generation Sequencing (NGS) service assay that allows a comprehensive DNA methylation profiling in human samples from...
Infinium Mouse Methylation Array Service
The Infinium Mouse Methylation Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology...
MeDIP-seq service (Methylated DNA IP Sequencing)
Methylated DNA immunoprecipitation sequencing (MeDIP-Seq) is used to study 5-mC genome-wide. In this assay, specific antibodies against 5-mC are used to capt...
Targeted Bisulfite Sequencing Service
Targeted bisulfite sequencing enables DNA methylation analysis of targeted genomic regions with single nucleotide resolution. Depending on the size of the re...