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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p><strong>Differential methylation analysis</strong></p>
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p>Our Epigenomics Profiling Services assure the sample preparation expertise and quality data that you seek. We provide epigenome-wide analyses for understanding epigenetic mechanisms, epigenetics-related drug discovery, transgenerational epigenetics studies, epigenetic biomarker identification (including epigenomic cancer biomarkers), and functional epigenomics. Diagenode offers expert epigenomics services that you can trust for chromatin, DNA, and RNA analysis. </p>
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<div class="small-12 medium-2 large-2 columns text-left"><img src="https://www.diagenode.com/img/logo-scientist-registered-supplier.png" /></div>
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<center><img alt="DNA-RNA-Chromatin-Diagenode" src="https://www.diagenode.com/img/categories/services/chromatin-dna-rna.png" /></center>
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<div class="panel" style="border-color: #099f92;">
<h3><span class="green">Chromatin</span> analysis</h3>
<ul>
<li>ChIP-seq analysis Histone modification</li>
<li>Promoter analysis</li>
<li>Enhancer analysis</li>
<li>ChIP-seq analysis Transcription factor </li>
<li>(sc)ATAC-seq Chromatin accessibility</li>
<li>ChIP-seq Cas9 off-target</li>
<li>Customized NGS service</li>
</ul>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/chip-seq-service">Learn more</a></p>
</div>
</div>
<div class="small-12 medium-4 large-4 columns text-left">
<div class="panel" style="border-color: #474546;">
<h3><span class="darkgrey">DNA methylation</span> analysis</h3>
<ul>
<li>Reduced representation bisulfite sequencing (RRBS)</li>
<li>Whole genome bisulfite sequencing (WGBS)</li>
<li>Targeted methylation</li>
<li>MeDIP-seq/hMeDIP-seq</li>
<li>Infinium MethylationEPIC array </li>
</ul>
<p></p>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/dna-methylation-profiling-services">Learn more</a></p>
</div>
</div>
<div class="small-12 medium-4 large-4 columns text-left">
<div class="panel" style="border-color: #b11e33;">
<h3><span class="diacol"><g class="gr_ gr_44 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="44" data-gr-id="44">RNA-seq</g></span> analysis</h3>
<ul>
<li><span style="display: inline !important; float: none; background-color: #f8f8f8; color: #333333; font-family: Helvetica,Arial,sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">Gene expression profiling</span></li>
<li>mRNA<span style="display: inline !important; float: none; background-color: #f8f8f8; color: #333333; font-family: Helvetica,Arial,sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"> analysis</span></li>
<li>Small non-coding RNA analysis</li>
<li><b></b>Whole transcriptome analysis<br /><br /><br /><br /><br /></li>
</ul>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/rna-seq-category">Learn more</a></p>
</div>
</div>
</div>
<h2 style="text-align: center;"><a class="details radius small button" href="https://www.diagenode.com/en/documents/services-flyer">DOWNLOAD OUR FLYER</a></h2>
<h2>Why Diagenode</h2>
<ul>
<li><strong>Expertise and trust</strong>: Recognized epigenetics leader, official partner of <a href="http://www.blueprint-epigenome.eu/"><g class="gr_ gr_45 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="45" data-gr-id="45">BLUEPRINT</g></a>, <a href="http://ihec-epigenomes.org/">IHEC</a> <g class="gr_ gr_46 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Punctuation only-ins replaceWithoutSep" id="46" data-gr-id="46">and</g> <a href="https://www.faang.org/">FAANG</a></li>
<li><strong>Innovative technology</strong>: Utilization of the signature Bioruptor<sup>®</sup> sonication device for optimal chromatin and DNA shearing and the IP-Star<sup>®</sup> Automation device give reproducible and reliable optimization and results</li>
<li><strong>Quality</strong>: Multiple QC steps in all workflows and validated antibodies plus reagents deliver superior data</li>
<li><strong>Flexibility</strong>: Extensive range of sample species and sample origins</li>
<li><strong>Experience</strong> in epigenomics profiling for a wide range of applications and fields of interest</li>
</ul>
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<div class="block-distri"><span class="label-green" style="margin-bottom: 16px; margin-left: -3px;">HUMAN</span><center><img width="260" height="259" alt="services chip-seq - human" src="https://www.diagenode.com/img/categories/services/services-humans.png" caption="false" /></center></div>
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<li>
<div class="block-distri"><span class="label-green" style="margin-bottom: 16px; margin-left: -3px;">ANIMALS</span><center><img width="260" height="259" alt="services chip-seq - animals" src="https://www.diagenode.com/img/categories/services/services-animals.png" caption="false" /></center></div>
</li>
<li>
<div class="block-distri"><span class="label-green" style="margin-bottom: 16px; margin-left: -3px;">PLANTS</span><center><img width="260" height="259" alt="services methylation-plant" src="https://www.diagenode.com/img/categories/services/services-plants.png" caption="false" /></center></div>
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<h2>12 years of expertise and trust in epigenetics</h2>
<ul>
<li><strong>End-to-end</strong> epigenetic service</li>
<li><strong>Collaborative</strong> and customized project design</li>
<li>Dedicated <strong>in-house expert</strong> for your project</li>
<li><strong>Integrative</strong> data analysis</li>
<li>Presentation-<strong>quality data</strong> and graphs</li>
</ul>
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<div class="small-12 medium-4 large-4 columns">
<div class="panel"><center><img src="http://www.diagenode.com/img/categories/services/dna-workflow.png" alt="DNA-methylation -Diagenode" /></center>
<p>DNAメチル化およびヒストン修飾のパターンは、細胞機能を維持する上で不可欠な役割を果たします。 異常なDNAメチル化 - 過剰メチル化および低メチル化 - は、癌または他の疾患のような有害転帰をもたらし得ます。ゲノムワイドDNAメチル化分析による5-mCの定量化は、疾患の検出および予後のための情報を提供することが可能です。 DiagenodeのDNAメチル化解析サービスは、あらゆる種のゲノムDNAメチル化解析の標的となる全ゲノムDNAメチル化解析用の多数のバイサルファイトシークエンシングオプションをご提供いたします。</p>
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<center><img src="https://www.diagenode.com/img/logo-scientist-registered-supplier.png" /></center></div>
<div class="small-12 medium-8 large-8 columns">
<p>エピゲノミクスプロファイリングサービスは、全ゲノムまたは遺伝子スケールのDNAメチル化のニーズに応じた最適なソリューションをご提案し、DNAメチル化（5-mC）およびメチル化変異体（5-hmC）研究をサポートします。DNAシーケンスのためのライブラリー調製やアレイから高品質のデータをお届けし、当社のバイオインフォマティクスの専門チームがお客様の研究内容に合わせて、カスタマイズされた解析を含む包括的なサービスを提供します。<br /><br /></p>
<h3><a href="https://www.diagenode.com/jp/p/infinium-methylation-epic-array-service">Infinium MethylationEPIC Array Service</a></h3>
<ul>
<li>所要時間の短縮、高いコストパフォーマンス</li>
<li>単一ヌクレオチド分解能で850,000を超えるヒトCpG位置</li>
<li>CpG、非CpG、およびCHH部位のメチル化部位の定量分析</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
</ul>
<h3><a href="https://www.diagenode.com/jp/p/infinium-mouse-methylation-array-service">Infinium Mouse Methylation Array Service</a></h3>
<ul>
<li>費用対効果が高いソリューション、所要時間の短縮</li>
<li>単一ヌクレオチド分解能で285,000を超えるマウスCpG位置</li>
<li>一般的な実験用マウス系に適応</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
</ul>
<h3><a href="https://www.diagenode.com/jp/p/rrbs-service">Reduced Representation Bisulfite Sequencing (RRBS) サービス</a></h3>
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<li>結果に自信のある堅牢で費用効果の高いソリューション</li>
<li>単一ヌクレオチド分解能で最大500万か所のCpG部位をカバー（ヒトサンプル）</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
<li>エピジェネティックなバイオマーカーの探索に最適</li>
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<h3><a href="https://www.diagenode.com/jp/p/wgbs-service">Whole Genome Bisulfite Sequencing (WGBS) Service</a></h3>
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<li>単一塩基分解能で全ゲノムのほぼ全てのCpG部位のメチル化状態を評価</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティックスツールによるゲノムにわたるCpG、CHGおよびCHH領域のメチル化パターン解析</a></li>
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<h3><a href="https://www.diagenode.com/jp/p/targeted-dna-methylation-service">Targeted Bisulfite Sequencing Service</a></h3>
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<li><span>Choose between two methodologies depending on the size of the region of interest: PCR enrichment or hybridization capture</span></li>
<li><span>Enhanced accuracy, sensitivity and specificity while reducing overall cost</span></li>
<li><span>Allowing deep sequencing at high coverage levels for rare variant identification</span></li>
</ul>
<h3><a href="../p/medip-seq-service">MeDIP</a></h3>
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<div class="small-12 medium-10 large-10 columns text-left">
<p>Our Epigenomics Profiling Services assure the sample preparation expertise and quality data that you seek. We provide epigenome-wide analyses for understanding epigenetic mechanisms, epigenetics-related drug discovery, transgenerational epigenetics studies, epigenetic biomarker identification (including epigenomic cancer biomarkers), and functional epigenomics. Diagenode offers expert epigenomics services that you can trust for chromatin, DNA, and RNA analysis. </p>
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<div class="small-12 medium-2 large-2 columns text-left"><img src="https://www.diagenode.com/img/logo-scientist-registered-supplier.png" /></div>
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<center><img alt="DNA-RNA-Chromatin-Diagenode" src="https://www.diagenode.com/img/categories/services/chromatin-dna-rna.png" /></center>
<div class="row">
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<div class="panel" style="border-color: #099f92;">
<h3><span class="green">Chromatin</span> analysis</h3>
<ul>
<li>ChIP-seq analysis Histone modification</li>
<li>Promoter analysis</li>
<li>Enhancer analysis</li>
<li>ChIP-seq analysis Transcription factor </li>
<li>(sc)ATAC-seq Chromatin accessibility</li>
<li>ChIP-seq Cas9 off-target</li>
<li>Customized NGS service</li>
</ul>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/chip-seq-service">Learn more</a></p>
</div>
</div>
<div class="small-12 medium-4 large-4 columns text-left">
<div class="panel" style="border-color: #474546;">
<h3><span class="darkgrey">DNA methylation</span> analysis</h3>
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<li>Reduced representation bisulfite sequencing (RRBS)</li>
<li>Whole genome bisulfite sequencing (WGBS)</li>
<li>Targeted methylation</li>
<li>MeDIP-seq/hMeDIP-seq</li>
<li>Infinium MethylationEPIC array </li>
</ul>
<p></p>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/dna-methylation-profiling-services">Learn more</a></p>
</div>
</div>
<div class="small-12 medium-4 large-4 columns text-left">
<div class="panel" style="border-color: #b11e33;">
<h3><span class="diacol"><g class="gr_ gr_44 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="44" data-gr-id="44">RNA-seq</g></span> analysis</h3>
<ul>
<li><span style="display: inline !important; float: none; background-color: #f8f8f8; color: #333333; font-family: Helvetica,Arial,sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">Gene expression profiling</span></li>
<li>mRNA<span style="display: inline !important; float: none; background-color: #f8f8f8; color: #333333; font-family: Helvetica,Arial,sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"> analysis</span></li>
<li>Small non-coding RNA analysis</li>
<li><b></b>Whole transcriptome analysis<br /><br /><br /><br /><br /></li>
</ul>
<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/rna-seq-category">Learn more</a></p>
</div>
</div>
</div>
<h2 style="text-align: center;"><a class="details radius small button" href="https://www.diagenode.com/en/documents/services-flyer">DOWNLOAD OUR FLYER</a></h2>
<h2>Why Diagenode</h2>
<ul>
<li><strong>Expertise and trust</strong>: Recognized epigenetics leader, official partner of <a href="http://www.blueprint-epigenome.eu/"><g class="gr_ gr_45 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="45" data-gr-id="45">BLUEPRINT</g></a>, <a href="http://ihec-epigenomes.org/">IHEC</a> <g class="gr_ gr_46 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Punctuation only-ins replaceWithoutSep" id="46" data-gr-id="46">and</g> <a href="https://www.faang.org/">FAANG</a></li>
<li><strong>Innovative technology</strong>: Utilization of the signature Bioruptor<sup>®</sup> sonication device for optimal chromatin and DNA shearing and the IP-Star<sup>®</sup> Automation device give reproducible and reliable optimization and results</li>
<li><strong>Quality</strong>: Multiple QC steps in all workflows and validated antibodies plus reagents deliver superior data</li>
<li><strong>Flexibility</strong>: Extensive range of sample species and sample origins</li>
<li><strong>Experience</strong> in epigenomics profiling for a wide range of applications and fields of interest</li>
</ul>
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<p>DNAメチル化およびヒストン修飾のパターンは、細胞機能を維持する上で不可欠な役割を果たします。 異常なDNAメチル化 - 過剰メチル化および低メチル化 - は、癌または他の疾患のような有害転帰をもたらし得ます。ゲノムワイドDNAメチル化分析による5-mCの定量化は、疾患の検出および予後のための情報を提供することが可能です。 DiagenodeのDNAメチル化解析サービスは、あらゆる種のゲノムDNAメチル化解析の標的となる全ゲノムDNAメチル化解析用の多数のバイサルファイトシークエンシングオプションをご提供いたします。</p>
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<h3><a href="https://www.diagenode.com/jp/p/infinium-methylation-epic-array-service">Infinium MethylationEPIC Array Service</a></h3>
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<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<h3><a href="https://www.diagenode.com/jp/p/rrbs-service">Reduced Representation Bisulfite Sequencing (RRBS) サービス</a></h3>
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<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
<li>エピジェネティックなバイオマーカーの探索に最適</li>
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<h3><a href="https://www.diagenode.com/jp/p/wgbs-service">Whole Genome Bisulfite Sequencing (WGBS) Service</a></h3>
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<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティックスツールによるゲノムにわたるCpG、CHGおよびCHH領域のメチル化パターン解析</a></li>
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<h3><a href="https://www.diagenode.com/jp/p/targeted-dna-methylation-service">Targeted Bisulfite Sequencing Service</a></h3>
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<li><span>Enhanced accuracy, sensitivity and specificity while reducing overall cost</span></li>
<li><span>Allowing deep sequencing at high coverage levels for rare variant identification</span></li>
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<h3><a href="../p/medip-seq-service">MeDIP</a></h3>
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p>Our Epigenomics Profiling Services assure the sample preparation expertise and quality data that you seek. We provide epigenome-wide analyses for understanding epigenetic mechanisms, epigenetics-related drug discovery, transgenerational epigenetics studies, epigenetic biomarker identification (including epigenomic cancer biomarkers), and functional epigenomics. Diagenode offers expert epigenomics services that you can trust for chromatin, DNA, and RNA analysis. </p>
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<h3><span class="green">Chromatin</span> analysis</h3>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/chip-seq-service">Learn more</a></p>
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<h3><span class="darkgrey">DNA methylation</span> analysis</h3>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/dna-methylation-profiling-services">Learn more</a></p>
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<h3><span class="diacol"><g class="gr_ gr_44 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="44" data-gr-id="44">RNA-seq</g></span> analysis</h3>
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<li>mRNA<span style="display: inline !important; float: none; background-color: #f8f8f8; color: #333333; font-family: Helvetica,Arial,sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"> analysis</span></li>
<li>Small non-coding RNA analysis</li>
<li><b></b>Whole transcriptome analysis<br /><br /><br /><br /><br /></li>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/rna-seq-category">Learn more</a></p>
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<h2 style="text-align: center;"><a class="details radius small button" href="https://www.diagenode.com/en/documents/services-flyer">DOWNLOAD OUR FLYER</a></h2>
<h2>Why Diagenode</h2>
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<li><strong>Expertise and trust</strong>: Recognized epigenetics leader, official partner of <a href="http://www.blueprint-epigenome.eu/"><g class="gr_ gr_45 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="45" data-gr-id="45">BLUEPRINT</g></a>, <a href="http://ihec-epigenomes.org/">IHEC</a> <g class="gr_ gr_46 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Punctuation only-ins replaceWithoutSep" id="46" data-gr-id="46">and</g> <a href="https://www.faang.org/">FAANG</a></li>
<li><strong>Innovative technology</strong>: Utilization of the signature Bioruptor<sup>®</sup> sonication device for optimal chromatin and DNA shearing and the IP-Star<sup>®</sup> Automation device give reproducible and reliable optimization and results</li>
<li><strong>Quality</strong>: Multiple QC steps in all workflows and validated antibodies plus reagents deliver superior data</li>
<li><strong>Flexibility</strong>: Extensive range of sample species and sample origins</li>
<li><strong>Experience</strong> in epigenomics profiling for a wide range of applications and fields of interest</li>
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<h2>12 years of expertise and trust in epigenetics</h2>
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<div class="panel"><center><img src="http://www.diagenode.com/img/categories/services/dna-workflow.png" alt="DNA-methylation -Diagenode" /></center>
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<h3><a href="https://www.diagenode.com/jp/p/infinium-methylation-epic-array-service">Infinium MethylationEPIC Array Service</a></h3>
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<li>所要時間の短縮、高いコストパフォーマンス</li>
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<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<h3><a href="https://www.diagenode.com/jp/p/infinium-mouse-methylation-array-service">Infinium Mouse Methylation Array Service</a></h3>
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<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<h3><a href="https://www.diagenode.com/jp/p/rrbs-service">Reduced Representation Bisulfite Sequencing (RRBS) サービス</a></h3>
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<li>単一ヌクレオチド分解能で最大500万か所のCpG部位をカバー（ヒトサンプル）</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
<li>エピジェネティックなバイオマーカーの探索に最適</li>
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<h3><a href="https://www.diagenode.com/jp/p/wgbs-service">Whole Genome Bisulfite Sequencing (WGBS) Service</a></h3>
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<li>単一塩基分解能で全ゲノムのほぼ全てのCpG部位のメチル化状態を評価</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティックスツールによるゲノムにわたるCpG、CHGおよびCHH領域のメチル化パターン解析</a></li>
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<h3><a href="https://www.diagenode.com/jp/p/targeted-dna-methylation-service">Targeted Bisulfite Sequencing Service</a></h3>
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<li>Focus on D<span>NA methylation patterning of selective regions with single nucleotide resolution</span></li>
<li><span>Choose between two methodologies depending on the size of the region of interest: PCR enrichment or hybridization capture</span></li>
<li><span>Enhanced accuracy, sensitivity and specificity while reducing overall cost</span></li>
<li><span>Allowing deep sequencing at high coverage levels for rare variant identification</span></li>
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<h3><a href="../p/medip-seq-service">MeDIP</a></h3>
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p><span><i class="fa fa-arrow-circle-right"></i> </span><a href="https://www.diagenode.com/en/categories/dna-methylation-profiling-services">See our other DNA Methylation Profiling Services</a></p>',
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<p>Our Epigenomics Profiling Services assure the sample preparation expertise and quality data that you seek. We provide epigenome-wide analyses for understanding epigenetic mechanisms, epigenetics-related drug discovery, transgenerational epigenetics studies, epigenetic biomarker identification (including epigenomic cancer biomarkers), and functional epigenomics. Diagenode offers expert epigenomics services that you can trust for chromatin, DNA, and RNA analysis. </p>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/chip-seq-service">Learn more</a></p>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/dna-methylation-profiling-services">Learn more</a></p>
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<h3><span class="diacol"><g class="gr_ gr_44 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="44" data-gr-id="44">RNA-seq</g></span> analysis</h3>
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<li>Small non-coding RNA analysis</li>
<li><b></b>Whole transcriptome analysis<br /><br /><br /><br /><br /></li>
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<p><i class="fa fa-arrow-circle-right"></i> <a href="../categories/rna-seq-category">Learn more</a></p>
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<h2 style="text-align: center;"><a class="details radius small button" href="https://www.diagenode.com/en/documents/services-flyer">DOWNLOAD OUR FLYER</a></h2>
<h2>Why Diagenode</h2>
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<li><strong>Expertise and trust</strong>: Recognized epigenetics leader, official partner of <a href="http://www.blueprint-epigenome.eu/"><g class="gr_ gr_45 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace" id="45" data-gr-id="45">BLUEPRINT</g></a>, <a href="http://ihec-epigenomes.org/">IHEC</a> <g class="gr_ gr_46 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Punctuation only-ins replaceWithoutSep" id="46" data-gr-id="46">and</g> <a href="https://www.faang.org/">FAANG</a></li>
<li><strong>Innovative technology</strong>: Utilization of the signature Bioruptor<sup>®</sup> sonication device for optimal chromatin and DNA shearing and the IP-Star<sup>®</sup> Automation device give reproducible and reliable optimization and results</li>
<li><strong>Quality</strong>: Multiple QC steps in all workflows and validated antibodies plus reagents deliver superior data</li>
<li><strong>Flexibility</strong>: Extensive range of sample species and sample origins</li>
<li><strong>Experience</strong> in epigenomics profiling for a wide range of applications and fields of interest</li>
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<h2>12 years of expertise and trust in epigenetics</h2>
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<div class="panel"><center><img src="http://www.diagenode.com/img/categories/services/dna-workflow.png" alt="DNA-methylation -Diagenode" /></center>
<p>DNAメチル化およびヒストン修飾のパターンは、細胞機能を維持する上で不可欠な役割を果たします。 異常なDNAメチル化 - 過剰メチル化および低メチル化 - は、癌または他の疾患のような有害転帰をもたらし得ます。ゲノムワイドDNAメチル化分析による5-mCの定量化は、疾患の検出および予後のための情報を提供することが可能です。 DiagenodeのDNAメチル化解析サービスは、あらゆる種のゲノムDNAメチル化解析の標的となる全ゲノムDNAメチル化解析用の多数のバイサルファイトシークエンシングオプションをご提供いたします。</p>
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<p>エピゲノミクスプロファイリングサービスは、全ゲノムまたは遺伝子スケールのDNAメチル化のニーズに応じた最適なソリューションをご提案し、DNAメチル化（5-mC）およびメチル化変異体（5-hmC）研究をサポートします。DNAシーケンスのためのライブラリー調製やアレイから高品質のデータをお届けし、当社のバイオインフォマティクスの専門チームがお客様の研究内容に合わせて、カスタマイズされた解析を含む包括的なサービスを提供します。<br /><br /></p>
<h3><a href="https://www.diagenode.com/jp/p/infinium-methylation-epic-array-service">Infinium MethylationEPIC Array Service</a></h3>
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<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<h3><a href="https://www.diagenode.com/jp/p/infinium-mouse-methylation-array-service">Infinium Mouse Methylation Array Service</a></h3>
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<li>単一ヌクレオチド分解能で285,000を超えるマウスCpG位置</li>
<li>一般的な実験用マウス系に適応</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
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<h3><a href="https://www.diagenode.com/jp/p/rrbs-service">Reduced Representation Bisulfite Sequencing (RRBS) サービス</a></h3>
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<li>結果に自信のある堅牢で費用効果の高いソリューション</li>
<li>単一ヌクレオチド分解能で最大500万か所のCpG部位をカバー（ヒトサンプル）</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><span><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティクスツール</a></span>によるDifferentially methylated site解析</li>
<li>エピジェネティックなバイオマーカーの探索に最適</li>
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<h3><a href="https://www.diagenode.com/jp/p/wgbs-service">Whole Genome Bisulfite Sequencing (WGBS) Service</a></h3>
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<li>単一塩基分解能で全ゲノムのほぼ全てのCpG部位のメチル化状態を評価</li>
<li>全ゲノム上CpG-rich部位とプロモーターのメチレーションパターン解析</li>
<li><a href="https://www.diagenode.com/jp/categories/bioinformatics-service">バイオインフォマティックスツールによるゲノムにわたるCpG、CHGおよびCHH領域のメチル化パターン解析</a></li>
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<h3><a href="https://www.diagenode.com/jp/p/targeted-dna-methylation-service">Targeted Bisulfite Sequencing Service</a></h3>
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<li>Focus on D<span>NA methylation patterning of selective regions with single nucleotide resolution</span></li>
<li><span>Choose between two methodologies depending on the size of the region of interest: PCR enrichment or hybridization capture</span></li>
<li><span>Enhanced accuracy, sensitivity and specificity while reducing overall cost</span></li>
<li><span>Allowing deep sequencing at high coverage levels for rare variant identification</span></li>
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<h3><a href="../p/medip-seq-service">MeDIP</a></h3>
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