Epigenomics Profiling Services

DNA Methylation Profiling Services

The pattern of DNA methylation and histone modi?cation(s) plays an essential role in maintaining cellular function. Abnormal DNA methylation – hypermethylation and hypomethylation - can result in adverse outcomes such as cancer or other disease. The quantification of 5-mC through genome-wide DNA methylation analysis can provide information for detection and prognosis of disease. Our DNA methylation analysis services include numerous bisulfite sequencing options for targeted or whole genome DNA methylation analysis across any species.

Illumina Infinium MethylationEPIC array BeadChip (850K)

Cost-effective with rapid turnaround time
Quantitative analysis of methylation sites in CpG, non-CpG, and CHH sites
Over 850,000 human CpG positions at single nucleotide resolution
Differentially methylated site analysis
Comprehensive services includes end-to-end bisulfite conversion, array hybridization, and analysis

Reduced representation bisulfite sequencing (RRBS)

RRBS provides a powerful method to efficiently analyze DNA methylation at the single nucleotide level without the higher costs associated with whole genome bisulfite sequencing. By cutting the genome using the restriction MspI enzyme (CCGG target sites) followed by size selection, DNA is enriched to represent CpG-rich regions (including CpG islands), in which DNA methylation marks are typically found. Thus, RRBS provides a cost-effective method for analyzing DNA methylation by reducing the part of the genome that actually needs to be sequenced and focusing on relevant CpG islands.

CpG rich region (5-mC): single nucleotide resolution
Epigenetic biomarker discovery
Methylation patterns of CpG rich regions across the genome
Covers up to 4M CpG sites in Human

Whole genome bisulfite sequencing (WGBS)

WGBS is designed to prepare single and paired-end bisulfite converted DNA libraries for sequencing using Illumina^® platforms. It has also been validated for bisulfite-converted library preparation from ChIP-derived samples in order to perform ChIP-Bis-Sequencing. Genome-wide bisulfite sequencing is suitable for studying DNA methylation sites and their role in gene regulation

Genome-wide 5-mC: single nucleotide resolution
Epigenetic biomarker discovery
Methylation patterns of CpG, CHG, and CHH regions across the genome
Epigenome-wide association studies (EWAS)

MeDIP/hMeDIP-seq

Targeted DNA methylation analysis

产品

目录号	产品	格式
G0209006	Infinium MethylationEPIC Array v2.0 Service The Infinium MethylationEPIC v2.0 Array Services (improved version of the EPIC v1.0) is the new cutting-edge genome-wide DNA methylation analysis t...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02020000	RRBS service (Reduced Representation Bisulfite Sequencing) Single-base resolution CpG detection with our popular Premium RRBS kit (internal bisulfite conversion controls included) Latest technology in bisulfite-...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02040000	WGBS service (Whole Genome Bisulfite Sequencing) Whole-genome bisulfite sequencing (WGBS) is the most comprehensive next generation sequencing for DNA methylation profiling, allowing single-base resol...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02100000	Bioinformatics Data Mining Service New! Data mining using machine learning (AI) for unique epigenetic data insights Watch the webinar to gain insights on how data mining can be applied ...	Custom	Get a quote You are about to request a quote for Bioinformatics Data Mining Service. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Comment ×
G02070000	Targeted DNA methylation service Targeted DNA methylation analysis allows for the quantitative study of cytosine methylation at known and precise locations throughout the genome. Depending o...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02180000	Human Methylome Service NEW! Human Methylome enables high coverage genome-wide DNA methylation analysis at the single nucleotide level in Human samples and it is ideal for biomarker...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×
G02160000	Infinium Mouse Methylation Array Service The Infinium Mouse Methylation Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology...		Get a quote You are about to request a quote for our epigenomics services. Fill out the form below and we will be in touch with you very soon. All * fields are mandatory Service Information Which services are you interested in? ChIP-seq ATAC-seq RRBS WGBS MeDIP-seq Targeted DNA methylation analysis Infinium MethylationEPIC Array v2 Infinium Mouse Methylation Array RNA-seq Bioinformatics Data mining Human Methylome Sample species Total number of samples (including replicates) Contact Information First name ^* Last name ^* Company ^* Phone number City Country ^* State Email ^* Email verification^* Project ×

活动

Long-Read Sequencing Meeting 2024
Uppsala, Sweden
Oct 21-Oct 23, 2024
NextGen Omics 2024
London, UK
Oct 23-Oct 25, 2024
FEBS 2024
Budapest, Hungary
Oct 28-Oct 31, 2024
5th Danube Conference on Epigenetics
Budapest, Hungary
Oct 28-Oct 31, 2024

查看所有活动

很高兴再次见到您！

Set country preference

To ensure you see the information most relevant to you, please select your country. Please note that your browser will need to be configured to accept cookies.

Diagenode will process your personal data in strict accordance with its privacy policy. This will include sending you updates about us, our products, and resources we think would be of interest to you.

Email verification^*