Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

CRISPR-Cas9 Structures and Mechanisms
Published: May, 2017

Abstract: Many bacterial CRISPR-Cas systems employ the dual-RNA-guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by in... Read more »

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Article alert
The Rhomboid Protease GlpG Promotes the Persistence of Extraintesti...
Published: April, 2017

Abstract: Extraintestinal pathogenic Escherichia coli (ExPEC) strains are typically benign within the  mammalian gut, but can disperse to extraintestina... Read more »

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Bioruptor
The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vit...
Published: March, 2017

Abstract: Background ELF2 (E74-like factor 2) also known as NERF (new Ets-related factor), a member of the Ets family of transcription factors, regulates ... Read more »

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Bioruptor
Epigenetically-driven anatomical diversity of synovial fibroblasts ...
Published: March, 2017

Abstract: A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show ... Read more »

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Antibody Microplex Library Preparation kit
JMJD3 aids in reprogramming of bone marrow progenitor cells to hepa...
Published: March, 2017

Abstract: The strictly regulated unidirectional differentiation program in some somatic stem/progenitor cells has been found to be modified in the ectopic si... Read more »

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LowCell ChIP kit
Islet-1 induces the differentiation of mesenchymal stem cells into ...
Published: March, 2017

Abstract: Previous studies from this group demonstrated that insulin gene enhancer binding protein ISL-1 (Islet-1) specifically induces the differentiation o... Read more »

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Bioruptor
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of...
Published: March, 2017

Abstract: Methylation of lysine residues on histone tail is a dynamic epigenetic modification that plays a key role in chromatin structure and gene regulatio... Read more »

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Antibody
Crebbp loss cooperates with Bcl2 over-expression to promote lymphom...
Published: March, 2017

Abstract: CREBBP is targeted by inactivating mutations in follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). Here, we provide evidence from ... Read more »

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ChIP-seq IP-Star IP-Star Compact
Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resi...
Published: March, 2017

Abstract: Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnor... Read more »

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Antibody
Conserved effect of aging on DNA methylation and association with E...
Published: February, 2017

Abstract: In humans, DNA methylation at specific CpG sites can be used to estimate the 'epigenetic clock', a biomarker of aging and health. The mechanisms th... Read more »

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MethylCap
Aorta macrophage inflammatory and epigenetic changes in a murine mo...
Published: February, 2017

Abstract: Obstructive sleep apnea (OSA) affects 8-10% of the population, is characterized by chronic intermittent hypoxia (CIH), and causally associates with... Read more »

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Antibody Microplex Library Preparation kit True MicroChIP kit
Inactivation of Lsd1 triggers senescence in trophoblast stem cells ...
Published: February, 2017

Abstract: Coordination of energy metabolism is essential for homeostasis of stem cells, whereas an imbalance in energy homeostasis causes disease and acceler... Read more »

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IP-Star Compact
An endoparasitoid wasp influences host DNA methylation
Published: February, 2017

Abstract: Parasitism by endoparasitoid wasps changes the expression of various host genes, and alters host immune and developmental processes. However, it is... Read more »
Intestinal NCoR1, a regulator of epithelial cell maturation, contro...
Published: February, 2017

Abstract: Severe neonatal hyperbilirubinemia (SNH) and the onset of bilirubin encephalopathy and kernicterus result in part from delayed expression of UDP-gl... Read more »

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Microplex Library Preparation kit
H3.Y discriminates between HIRA and DAXX chaperone complexes and re...
Published: February, 2017

Abstract: Histone chaperones prevent promiscuous histone interactions before chromatin assembly. They guarantee faithful deposition of canonical histones and... Read more »

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Antibody Microplex Library Preparation kit
Overexpression of LINE-1 Retrotransposons in Autism Brain
Published: February, 2017

Abstract: Long interspersed nuclear elements-1 (LINE-1 or L1) are mobile DNA sequences that are capable of duplication and insertion (retrotransposition) wit... Read more »

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MagMeDIP kit
RNF40 regulates gene expression in an epigenetic context-dependent ...
Published: February, 2017

Abstract: BACKGROUND: Monoubiquitination of H2B (H2Bub1) is a largely enigmatic histone modification that has been linked to transcriptional elongation. B... Read more »

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Antibody
Jmjd2c/Kdm4c facilitates the assembly of essential enhancer-protein...
Published: February, 2017

Abstract: Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exi... Read more »

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Antibody
Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) o...
Published: February, 2017

Abstract: Both Reelin (RELN) and glutamate decarboxylase 67 (GAD1) have been implicated in the pathophysiology of Autism Spectrum Disorders (ASD). We have pr... Read more »

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Antibody
The non-coding variant rs1800734 enhances DCLK3 expression through ...
Published: February, 2017

Abstract: Genome-wide association studies have identified a great number of non-coding risk variants for colorectal cancer (CRC). To date, the majority of th... Read more »

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Antibody
Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27...
Published: February, 2017

Abstract: Although Men1 is a well-known tumour suppressor gene, little is known about the functions of Menin, the protein it encodes for. Since few years, nu... Read more »

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Antibody
Foxa2, a novel protein partner of tumour suppressor menin, is dereg...
Published: February, 2017

Abstract: Foxa2, known as one of the pioneer factors, plays a crucial role in islet development and endocrine functions. Its expression and biological functi... Read more »
A novel DLX3-PKC integrated signaling network drives keratinocyte d...
Published: February, 2017

Abstract: Epidermal homeostasis relies on a well-defined transcriptional control of keratinocyte proliferation and differentiation, which is critical to prev... Read more »

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Antibody
H3K23me1 is an evolutionarily conserved histone modification associ...
Published: February, 2017

Abstract: Amino-terminal tails of histones are targets for diverse post-translational modifications whose combinatorial action may constitute a code that wil... Read more »

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Antibody IPure kit
Intergenerational Transmission of Enhanced Seizure Susceptibility a...
Published: February, 2017

Abstract: Environmental exposure early in development plays a role in susceptibility to disease in later life. Here, we demonstrate that prolonged febrile se... Read more »

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Antibody
Genome-wide analyses of four major histone modifications in Arabido...
Published: February, 2017

Abstract: Background Hybrid vigour (heterosis) has been used for decades in cropping agriculture, especially in the production of maize and rice, because ... Read more »

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Antibody
Heat Shock Induced Phosphorylation of TAR DNA Binding Protein 43 (T...
Published: February, 2017

Abstract: TAR DNA binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA process... Read more »
Faithful SGCE imprinting in iPSC-derived cortical neurons: an endog...
Published: February, 2017

Abstract: In neuropathology research, induced pluripotent stem cell (iPSC)-derived neurons are considered a tool closely resembling the patient brain. Albeit... Read more »

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Premium Bisulfite Kit
Genomic characterization and dynamic methylation of promoter facili...
Published: February, 2017

Abstract: Differential expression of homomorphous variants of H2A family of histone H2A.1 and H2A.2 have been associated with hepatocellular carcinoma and ma... Read more »

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Antibody
Suppression of RUNX1/ETO oncogenic activity by a small molecule inh...
Published: February, 2017

Abstract: RUNX1/ETO, the product of the t(8;21) chromosomal translocation, is required for the onset and maintenance of one of the most common forms of acute... Read more »

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Antibody

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