Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOW...
Published: June, 2017

Abstract: The transcription factors LEAFY (LFY) and APETALA1 (AP1), together with the AP1 paralog CAULIFLOWER (CAL), control the onset of flower development ... Read more »
CRISPR-Cas9 Structures and Mechanisms
Published: May, 2017

Abstract: Many bacterial CRISPR-Cas systems employ the dual-RNA-guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by in... Read more »

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Article alert
MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylati...
Published: May, 2017

Abstract: Background DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent s... Read more »

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MagMeDIP kit
Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcr...
Published: May, 2017

Abstract: Monocytes are circulating, short-lived mononuclear phagocytes, which in mice and man comprise two main subpopulations. MurineLy6C+ monocytes displa... Read more »

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Bioruptor
The adaptor protein ARA55 and the nuclear kinase HIPK1 assist c-Myb...
Published: May, 2017

Abstract: LIM-domain proteins, containing multiple cysteine-rich zinc finger-like motifs, have been shown to play diverse roles in several cellular processes... Read more »

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Bioruptor
TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cy...
Published: May, 2017

Abstract: Aberrant WNT signaling drives colorectal cancer (CRC). Here, we identify TIAM1 as a critical antagonist of CRC progression through inhibiting TAZ a... Read more »

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Microplex Library Preparation kit
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells...
Published: May, 2017

Abstract: BMP2 and TGFβ1 are functional antagonists of pathological remodeling in the arteries, heart, and lung; however, the mechanisms in VSMCs, and t... Read more »

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ChIP-seq IPure kit
sgs1: a neomorphic nac52 allele impairing PTGS through SGS3 down-re...
Published: May, 2017

Abstract: Post-transcriptional gene silencing (PTGS) is a defense mechanism that targets invading nucleic acids from endogenous (transposons) or exogenous (p... Read more »

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IPure kit
Novel Molecular Mechanism of Regulation of CD40 Ligand by the Trans...
Published: April, 2017

Abstract: The interaction between tumor cells and their surrounding microenvironment is essential for the growth and persistence of cancer cells. This intera... Read more »

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Bioruptor
Critical threshold levels of DNA methyltransferase 1 are required t...
Published: April, 2017

Abstract: Reversing DNA methylation abnormalities and associated gene silencing, through inhibiting DNA methyltransferases (DNMTs) is an important potential ... Read more »

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Antibody
DNA breaks and chromatin structural changes enhance the transcripti...
Published: April, 2017

Abstract: The autoimmune regulator (AIRE) protein is the key factor in thymic negative selection of autoreactive T cells by promoting the ectopic expression ... Read more »

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Antibody IP-Star Compact
Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcri...
Published: April, 2017

Abstract: CD95/Fas ligand (FasL) is a cell death-promoting member of the tumor necrosis factor family with important functions in the regulation of T-cell ho... Read more »

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IPure kit
Genomic responses of mouse synovial fibroblasts during TNF-driven a...
Published: April, 2017

Abstract: OBJECTIVE: Aberrant activation of synovial fibroblasts (SFs) is a key determinant in the pathogenesis of rheumatoid arthritis (RA). We aimed to pr... Read more »

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Bioruptor ChIP-seq Antibody
H2A monoubiquitination in Arabidopsis thaliana is generally indepen...
Published: April, 2017

Abstract: BACKGROUND: Polycomb group complexes PRC1 and PRC2 repress gene expression at the chromatin level in eukaryotes. The classic recruitment model o... Read more »

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Antibody
Global analysis of H3K27me3 as an epigenetic marker in prostate can...
Published: April, 2017

Abstract: BACKGROUND: H3K27me3 histone marks shape the inhibition of gene transcription. In prostate cancer, the deregulation of H3K27me3 marks might play... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Glucocorticoid receptor represses brain-derived neurotrophic factor...
Published: April, 2017

Abstract: Brain-derived neurotrophic factor (BDNF) is involved in many functions such as neuronal growth, survival, synaptic plasticity and memorization. Alt... Read more »

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ChIP-qPCR
Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Pro...
Published: April, 2017

Abstract: Transcription factors play a key role in the development of diverse cancers, and therapeutically targeting them has remained a challenge. In prosta... Read more »

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HighCell ChIP kit IPure kit
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by ...
Published: April, 2017

Abstract: The transcription factor Meis1 drives myeloid leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable... Read more »

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IPure kit
c-Myc Antagonises the Transcriptional Activity of the Androgen Rece...
Published: April, 2017

Abstract: Prostate cancer (PCa) is the most common non-cutaneous cancer in men. The androgen receptor (AR), a ligand-activated transcription factor, constitu... Read more »

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ChIP-seq Antibody H3K4me3 (C15410003) H3K27ac (C15410174) H3K27me3 (C15410195)
Male fertility status is associated with DNA methylation signatures...
Published: April, 2017

Abstract: BACKGROUND: Infertility in dairy cattle is a concern where reduced fertilization rates and high embryonic loss are contributing factors. Studies... Read more »

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MethylCap
The Rhomboid Protease GlpG Promotes the Persistence of Extraintesti...
Published: April, 2017

Abstract: Extraintestinal pathogenic Escherichia coli (ExPEC) strains are typically benign within the  mammalian gut, but can disperse to extraintestina... Read more »

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Bioruptor
Comparative analysis of MBD-seq and MeDIP-seq and estimation of gen...
Published: March, 2017

Abstract: We conducted a comparative study of multiplexed affinity enrichment sequence methodologies (MBD-seq and MeDIP-seq) in a rodent model of schizophren... Read more »

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MagMeDIP kit MethylCap
The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vit...
Published: March, 2017

Abstract: Background ELF2 (E74-like factor 2) also known as NERF (new Ets-related factor), a member of the Ets family of transcription factors, regulates ... Read more »

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Bioruptor
Epigenetically-driven anatomical diversity of synovial fibroblasts ...
Published: March, 2017

Abstract: A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show ... Read more »

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Antibody Microplex Library Preparation kit
Microinjection of Antibodies Targeting the Lamin A/C Histone-Bindin...
Published: March, 2017

Abstract: Lamins form a scaffold lining the nucleus that binds chromatin and contributes to spatial genome organization; however, due to the many other funct... Read more »

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Antibody
Epigenetically-driven anatomical diversity of synovial fibroblasts ...
Published: March, 2017

Abstract: A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show ... Read more »

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ChIP-seq
JMJD3 aids in reprogramming of bone marrow progenitor cells to hepa...
Published: March, 2017

Abstract: The strictly regulated unidirectional differentiation program in some somatic stem/progenitor cells has been found to be modified in the ectopic si... Read more »

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LowCell ChIP kit
Behavioral, transcriptomic and epigenetic responses to social chall...
Published: March, 2017

Abstract: Understanding how social experiences are represented in the brain and shape future responses is a major challenge in the study of behavior. We addr... Read more »

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ChIP-seq
mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation
Published: March, 2017

Abstract: CD4+ T cells lacking the mTORC1 activator Rheb fail to secrete IFN-γ under Th1 polarizing conditions. We hypothesized that this phenotype is ... Read more »
Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent ...
Published: March, 2017

Abstract: Wnt/β-catenin signaling is required for embryonic stem cell (ESC) pluripotency by inducing mesodermal differentiation and inhibiting neuronal ... Read more »

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Antibody

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