Publications
Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.
An expanded metabolic pathway for androgen production by commensal ...
Published: June, 2026
Abstract: Commensal bacteria have been implicated in the modulation of steroid hormones, including circulating androgen levels in the host. However, the micr... Read more »
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Megaruptor
Published: June, 2026
Abstract: Commensal bacteria have been implicated in the modulation of steroid hormones, including circulating androgen levels in the host. However, the micr... Read more »
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Megaruptor
A spatial multi-omics atlas of immunosenescence reveals germinal-ce...
Published: June, 2026
Abstract: Highlights • Spatial multi-omics atlas maps senescence across 51 human lymph nodes from ages 18–86 • Senescent-like cells shift from interfollicu... Read more »
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Tagmentase
Published: June, 2026
Abstract: Highlights • Spatial multi-omics atlas maps senescence across 51 human lymph nodes from ages 18–86 • Senescent-like cells shift from interfollicu... Read more »
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Tagmentase
Sustained PRC1.1 activity preserves gene repression independently o...
Published: June, 2026
Abstract: Loss-of-function mutations in BCOR, a subunit of the non-canonical Polycomb Repressive Complex 1.1 (PRC1.1), are frequently observed in acute myelo... Read more »
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Antibody
Published: June, 2026
Abstract: Loss-of-function mutations in BCOR, a subunit of the non-canonical Polycomb Repressive Complex 1.1 (PRC1.1), are frequently observed in acute myelo... Read more »
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Antibody
A Fetal Fraction Optimized 106-Plex Digital PCR Assay for Non-Invas...
Published: May, 2026
Abstract: Background/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal f... Read more »
Published: May, 2026
Abstract: Background/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal f... Read more »
New mechanistic insights from alignment of accessible chromatin and...
Published: May, 2026
Abstract: Genome-wide association studies for kidney function identified hundreds of genomic signals overlapping non-coding regions. Prioritizing regulated t... Read more »
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CUT&Tag
Published: May, 2026
Abstract: Genome-wide association studies for kidney function identified hundreds of genomic signals overlapping non-coding regions. Prioritizing regulated t... Read more »
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CUT&Tag
A scalable Tn5-based method for genome-wide DNA methylation profili...
Published: May, 2026
Abstract: DNA methylation is a key epigenetic modification involved in development and disease, including cancer, and serves as a biomarker for diagnosis. Cu... Read more »
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Antibody
Published: May, 2026
Abstract: DNA methylation is a key epigenetic modification involved in development and disease, including cancer, and serves as a biomarker for diagnosis. Cu... Read more »
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Antibody
Gut microbiome components predict response to neoadjuvant short-cou...
Published: May, 2026
Abstract: Background Although the gut microbiome shapes responses to anti-tumor immunotherapy and chemotherapy, its predictive value for neoadjuvant short-c... Read more »
Published: May, 2026
Abstract: Background Although the gut microbiome shapes responses to anti-tumor immunotherapy and chemotherapy, its predictive value for neoadjuvant short-c... Read more »
Molecular profiling of alpha-synuclein pathology and seeding activi...
Published: May, 2026
Abstract: Parkinson’s disease (PD) is neuropathologically characterized by the abnormal accumulation of fibrillar alpha-synuclein (aSyn) within selectively v... Read more »
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Bioruptor Plus
Published: May, 2026
Abstract: Parkinson’s disease (PD) is neuropathologically characterized by the abnormal accumulation of fibrillar alpha-synuclein (aSyn) within selectively v... Read more »
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Bioruptor Plus
Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a no...
Published: May, 2026
Abstract: Glycoprotein nonmetastatic melanoma B (GPNMB) is critical to cellular uptake of pathological forms of alpha-synuclein (aSyn), the hallmark disease ... Read more »
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Bioruptor Plus
Published: May, 2026
Abstract: Glycoprotein nonmetastatic melanoma B (GPNMB) is critical to cellular uptake of pathological forms of alpha-synuclein (aSyn), the hallmark disease ... Read more »
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Bioruptor Plus
Convergent evolution of intestinal lineages in the phylum Methanoba...
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
Pervasive and programmed nucleosome distortion on single chromatin ...
Published: April, 2026
Abstract: Despite decades of biochemical and structural studies of the nucleosome, researchers lack genome-scale methods to determine variability in nucleoso... Read more »
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Megaruptor
Published: April, 2026
Abstract: Despite decades of biochemical and structural studies of the nucleosome, researchers lack genome-scale methods to determine variability in nucleoso... Read more »
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Megaruptor
MeCP2 gene dosage-dependent neurodevelopmentally restricted defects...
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Exploring tear biomarkers with shotgun proteomics for retinoblastom...
Published: April, 2026
Abstract: The most common ocular neoplasia among children is retinoblastoma. Currently, the diagnosis of this disease is essentially clinical, taking a biops... Read more »
Published: April, 2026
Abstract: The most common ocular neoplasia among children is retinoblastoma. Currently, the diagnosis of this disease is essentially clinical, taking a biops... Read more »
Oxidative stress causes a reversible decrease of deubiquitylases ac...
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinosit...
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
TGF-β/SMAD4/14-3-3σ/TFEB axis promotes mesenchymal-epithelial trans...
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Population differences of chromosome 22q11.2 duplication structure ...
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, ...
Published: April, 2026
Abstract: Pathological remodeling in cardiomyocytes during heart failure is driven by excessive activation of mTORC1. Preclinical studies in mice demonst... Read more »
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D-Plex small RNA-seq
Published: April, 2026
Abstract: Pathological remodeling in cardiomyocytes during heart failure is driven by excessive activation of mTORC1. Preclinical studies in mice demonst... Read more »
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D-Plex small RNA-seq
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lys...
Published: April, 2026
Abstract: Histone modifications, including Nε-lysine acetylation and methylation, play critical roles in the regulation of eukaryotic transcription. The addi... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: Histone modifications, including Nε-lysine acetylation and methylation, play critical roles in the regulation of eukaryotic transcription. The addi... Read more »
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Bioruptor Plus
STAG2 loss amplifies EWS-FLI1-driven microsatellite enhancer activi...
Published: April, 2026
Abstract: Ewing sarcoma is driven by chromosomal translocations that fuse a FET RNA-binding protein to an ETS transcription factor, most commonly generatin... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Published: April, 2026
Abstract: Ewing sarcoma is driven by chromosomal translocations that fuse a FET RNA-binding protein to an ETS transcription factor, most commonly generatin... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Proof-of-concept study for the detection of somatic structural vari...
Published: April, 2026
Abstract: Gene fusions are common primary drivers of pediatric leukemias and are the result of underlying structural variants (SVs). Current clinical workflo... Read more »
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Megaruptor
Published: April, 2026
Abstract: Gene fusions are common primary drivers of pediatric leukemias and are the result of underlying structural variants (SVs). Current clinical workflo... Read more »
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Megaruptor
Newly isolated human-derived Lactobacillus fermentum strain stimula...
Published: April, 2026
Abstract: The gut microbiota represents a promising target to enhance cancer immunotherapy, yet the microbial molecules mediating anti-tumor immunity remain ... Read more »
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Megaruptor
Published: April, 2026
Abstract: The gut microbiota represents a promising target to enhance cancer immunotherapy, yet the microbial molecules mediating anti-tumor immunity remain ... Read more »
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Megaruptor
A Cisplatin-Based Prodrug Inhibits Nucleotide Excision Repair Indep...
Published: April, 2026
Abstract: Cisplatin [cis-diamminedichloroplatinum(II)] is a widely used chemotherapeutic agent that induces cytotoxicity primarily through DNA damage; howeve... Read more »
Published: April, 2026
Abstract: Cisplatin [cis-diamminedichloroplatinum(II)] is a widely used chemotherapeutic agent that induces cytotoxicity primarily through DNA damage; howeve... Read more »
A single small molecule-based human embryo model reveals V-ATPase r...
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
A novel temperate phage from Alicyclobacillus: first evidence in th...
Published: April, 2026
Abstract: Bacteriophages are increasingly explored as clean-label, environmentally friendly tools for sustainable food processing. Several phage-based produc... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: Bacteriophages are increasingly explored as clean-label, environmentally friendly tools for sustainable food processing. Several phage-based produc... Read more »
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Bioruptor Plus
BMAL2 is a druggable target for ovarian clear cell carcinoma (OCCC)
Published: April, 2026
Abstract: Ovarian clear cell carcinomas (OCCC), particularly cases that retain wild-type AT-rich interactive domain 1 A (ARID1A) expression (approximately 50... Read more »
Published: April, 2026
Abstract: Ovarian clear cell carcinomas (OCCC), particularly cases that retain wild-type AT-rich interactive domain 1 A (ARID1A) expression (approximately 50... Read more »
Stage-specific epigenetic priming amplifies gene activation during ...
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Completely resolved structural variants by optical genome mapping w...
Published: March, 2026
Abstract: Structural variants (SVs), including duplications, deletions, inversions, translocations, and insertions, play major roles in human phenotypic dive... Read more »
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Megaruptor
Published: March, 2026
Abstract: Structural variants (SVs), including duplications, deletions, inversions, translocations, and insertions, play major roles in human phenotypic dive... Read more »
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Megaruptor
Dissociation Between Metabolic Improvements and Mitochondrial Trans...
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
chromIDEAS reveals epigenetic dynamics via multi-dimensional cluste...
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus