Diagenode

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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Jmjd2c/Kdm4c facilitates the assembly of essential enhancer-protein...
Published: February, 2017

Abstract: Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exi... Read more »

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Antibody
Foxa2, a novel protein partner of tumour suppressor menin, is dereg...
Published: February, 2017

Abstract: Foxa2, known as one of the pioneer factors, plays a crucial role in islet development and endocrine functions. Its expression and biological functi... Read more »
Intergenerational Transmission of Enhanced Seizure Susceptibility a...
Published: February, 2017

Abstract: Environmental exposure early in development plays a role in susceptibility to disease in later life. Here, we demonstrate that prolonged febrile se... Read more »

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Antibody
Heat Shock Induced Phosphorylation of TAR DNA Binding Protein 43 (T...
Published: February, 2017

Abstract: TAR DNA binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA process... Read more »
Faithful SGCE imprinting in iPSC-derived cortical neurons: an endog...
Published: February, 2017

Abstract: In neuropathology research, induced pluripotent stem cell (iPSC)-derived neurons are considered a tool closely resembling the patient brain. Albeit... Read more »

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Premium Bisulfite Kit
Genomic characterization and dynamic methylation of promoter facili...
Published: February, 2017

Abstract: Differential expression of homomorphous variants of H2A family of histone H2A.1 and H2A.2 have been associated with hepatocellular carcinoma and ma... Read more »

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Antibody
Suppression of RUNX1/ETO oncogenic activity by a small molecule inh...
Published: February, 2017

Abstract: RUNX1/ETO, the product of the t(8;21) chromosomal translocation, is required for the onset and maintenance of one of the most common forms of acute... Read more »

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Antibody
Muscle catabolic capacities and global hepatic epigenome are modifi...
Published: February, 2017

Abstract: Based on the concept of nutritional programming in mammals, we tested whether a short term hyper or hypo vitamin stimulus during first-feeding coul... Read more »

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Antibody
Pharmacological inhibition of DNA methyltransferase 1 promotes neur...
Published: February, 2017

Abstract: Nasal olfactory stem and neural progenitor cells (NOS/PCs) are considered possible tools for regenerative stem cell therapies in neurodegenerative ... Read more »

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Antibody
Chromatin Domain Organization of TCRb locus and its perturbation by...
Published: January, 2017

Abstract: CTCF mediated chromatin interactions influence organization and function of mammalian genome in diverse ways. We analyzed the interactions amongst ... Read more »

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LowCell ChIP kit
Snail2 and Zeb2 repress P-Cadherin to define embryonic territories ...
Published: January, 2017

Abstract: Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct repression of E-Cadh... Read more »

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Antibody
Epigenetic sampling effects: nephrectomy modifies the clear cell re...
Published: January, 2017

Abstract: Purpose Currently, it is unclear to what extent sampling procedures affect the epigenome. Here, this phenomenon was evaluated by studying the im... Read more »

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MethylCap
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through deg...
Published: January, 2017

Abstract: Polycomb proteins are critical chromatin modifiers that regulate stem cell differentiation via transcriptional repression. In skeletal muscle proge... Read more »

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Antibody
Differentiation of Mouse Enteric Nervous System Progenitor Cells is...
Published: January, 2017

Abstract: Background & Aims Maintenance and differentiation of progenitor cells in the developing enteric nervous system (ENS) are controlled by molec... Read more »

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Bioruptor Antibody True MicroChIP kit
Rapid Recall Ability of Memory T cells is Encoded in their Epigenome
Published: January, 2017

Abstract: Even though T-cell receptor (TCR) stimulation together with co-stimulation is sufficient for the activation of both naïve and memory T cells, ... Read more »

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Antibody IP-Star Compact
Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryo...
Published: January, 2017

Abstract: Background Recent work has identified and mapped a range of posttranscriptional modifications in mRNA, including methylation of the N6 and N1 po... Read more »

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Antibody
Determinants of orofacial clefting II: Effects of 5-Aza-2′-deoxycyt...
Published: January, 2017

Abstract: Defects in development of the secondary palate, which arise from the embryonic first branchial arch (1-BA), can cause cleft palate (CP). Administra... Read more »

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MethylCap
The Role of Angiotensin Converting Enzyme 1 within the median preop...
Published: December, 2016

Abstract: Sustained hypertension is an important consequence of obstructive sleep apnea. An animal model of the hypoxemia associated with sleep apnea, chroni... Read more »

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LowCell ChIP kit
Arabidopsis SWI/SNF chromatin remodeling complex binds both promote...
Published: December, 2016

Abstract: ATP-dependent chromatin remodeling complexes are important regulators of gene expression in Eukaryotes. In plants, SWI/SNF-type complexes have been... Read more »

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Bioruptor Antibody
Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels...
Published: December, 2016

Abstract: Cyclosporine A (CsA) is an undecapeptide with strong immunosuppressant activities and is used a lot after organ transplantation. Furthermore, it ma... Read more »

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MagMeDIP kit
Stem cell-like transcriptional reprogramming mediates metastatic
Published: December, 2016

Abstract: Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggress... Read more »

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Bioruptor HighCell ChIP kit
Evaluating the Feasibility of DNA Methylation Analyses Using Long-T...
Published: December, 2016

Abstract: We here characterize the usability of archival formalin-fixed paraffin-embedded (FFPE) brain tissue as a resource for genetic and DNA methylation a... Read more »

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Bioruptor MagMeDIP kit IP-Star Compact
Co-occurrence of Histone H3 K27M and BRAF V600E mutations in paedia...
Published: December, 2016

Abstract: Ganglioglioma (GG) is a grade I tumour characterized by alterations in the MAPK pathway, including BRAF V600E mutation. Recently, diffuse midline g... Read more »

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Antibody
Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9...
Published: December, 2016

Abstract: The functionality of stem cells declines during ageing, and this decline contributes to ageing-associated impairments in tissue regeneration and fu... Read more »

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Antibody
Nitric oxide modulates histone acetylation at stress genes by inhib...
Published: December, 2016

Abstract: Histone acetylation, which is an important mechanism to regulate gene expression, is controlled by the opposing action of histone acetyltransferase... Read more »

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Bioruptor Antibody IPure kit Microplex Library Preparation kit
Alu repeats as transcriptional regulatory platforms in macrophage r...
Published: December, 2016

Abstract: To understand the epigenetic regulation of transcriptional response of macrophages during early-stage M. tuberculosis (Mtb) infection, we performed... Read more »

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Bioruptor
Voluntary Physical Exercise Induces Expression and Epigenetic Remod...
Published: December, 2016

Abstract: A healthy lifestyle, including regular physical exercise, is generally believed to improve cognitive function and enhance neurogenesis. Such physic... Read more »
Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic ...
Published: December, 2016

Abstract: Induction of trained immunity (innate immune memory) is mediated by activation of immune and metabolic pathways that result in epigenetic rewiring ... Read more »

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Antibody
FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of ...
Published: December, 2016

Abstract: FOXA1 is a pioneer factor that binds to enhancer regions that are enriched in H3K4 mono- and dimethylation (H3K4me1 and H3K4me2). We performed a FO... Read more »

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Antibody
Immunometabolic Pathways in BCG-Induced Trained Immunity
Published: December, 2016

Abstract: The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term m... Read more »

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Antibody

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