Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Increased 5-hydroxymethylation levels in the hippocampus of rat ext...
Published: July, 2017

Abstract: Drug craving and relapse risk during abstinence from cocaine are thought to be caused by persistent changes in transcription and chromatin regulati... Read more »

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Antibody
The epigenetic architecture at gene promoters determines cell type-...
Published: July, 2017

Abstract: Synovial fibroblasts (SF) drive inflammation and joint destruction in chronic arthritis. Here we show that SF possess a distinct type of LPS tolera... Read more »

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ChIP-seq
Methylome analysis of extreme chemoresponsive patients identifies n...
Published: June, 2017

Abstract: BACKGROUND: Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of... Read more »

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MethylCap
Inhibition of Histone H3K9 Methylation by BIX-01294 Promotes Stress...
Published: June, 2017

Abstract: Microspore embryogenesis is a process of cell reprogramming, totipotency acquisition and embryogenesis initiation, induced in vitro by stress treat... Read more »

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Antibody
Performance of four modern whole genome amplification methods for c...
Published: June, 2017

Abstract: Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of c... Read more »

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IP-Star Compact
Dynamics of DNA methylomes underlie oyster development
Published: June, 2017

Abstract: DNA methylation is a critical epigenetic regulator of development in mammals and social insects, but its significance in development outside these ... Read more »

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MagMeDIP kit
ICF-specific DNMT3B dysfunction interferes with intragenic regulati...
Published: June, 2017

Abstract: Hypomorphic mutations in DNA-methyltransferase DNMT3B cause majority of the rare disorder Immunodeficiency, Centromere instability and Facial anoma... Read more »

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Antibody
Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOW...
Published: June, 2017

Abstract: The transcription factors LEAFY (LFY) and APETALA1 (AP1), together with the AP1 paralog CAULIFLOWER (CAL), control the onset of flower development ... Read more »
CRISPR-Cas9 Structures and Mechanisms
Published: May, 2017

Abstract: Many bacterial CRISPR-Cas systems employ the dual-RNA-guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by in... Read more »

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Article alert
MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylati...
Published: May, 2017

Abstract: Background DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent s... Read more »

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MagMeDIP kit
Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription f...
Published: May, 2017

Abstract: Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at lysine 27 (H3K27ac) are correlated with transcriptionally enga... Read more »

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Antibody
Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcr...
Published: May, 2017

Abstract: Monocytes are circulating, short-lived mononuclear phagocytes, which in mice and man comprise two main subpopulations. MurineLy6C+ monocytes displa... Read more »

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Bioruptor
RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of Pol...
Published: May, 2017

Abstract: POLR3G is expressed at high levels in human pluripotent stem cells (hPSCs) and is required for maintenance of stem cell state through mechanisms no... Read more »

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Antibody Microplex Library Preparation kit
The adaptor protein ARA55 and the nuclear kinase HIPK1 assist c-Myb...
Published: May, 2017

Abstract: LIM-domain proteins, containing multiple cysteine-rich zinc finger-like motifs, have been shown to play diverse roles in several cellular processes... Read more »

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Bioruptor
TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cy...
Published: May, 2017

Abstract: Aberrant WNT signaling drives colorectal cancer (CRC). Here, we identify TIAM1 as a critical antagonist of CRC progression through inhibiting TAZ a... Read more »

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Microplex Library Preparation kit
CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenet...
Published: May, 2017

Abstract: An oncogenic role for CHD4, a NuRD component, is defined for initiating and supporting tumor suppressor gene (TSG) silencing in human colorectal ca... Read more »

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Antibody
The Dynamic Epigenetic Landscape of the Retina During Development, ...
Published: May, 2017

Abstract: In the developing retina, multipotent neural progenitors undergo unidirectional differentiation in a precise spatiotemporal order. Here we profile ... Read more »

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ChIP-seq Antibody
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells...
Published: May, 2017

Abstract: BMP2 and TGFβ1 are functional antagonists of pathological remodeling in the arteries, heart, and lung; however, the mechanisms in VSMCs, and t... Read more »

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ChIP-seq IPure kit
Mercury-induced epigenetic transgenerational inheritance of abnorma...
Published: May, 2017

Abstract: Methylmercury (MeHg) is a ubiquitous environmental neurotoxicant, with human exposures predominantly resulting from fish consumption. Developmental... Read more »

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Antibody
sgs1: a neomorphic nac52 allele impairing PTGS through SGS3 down-re...
Published: May, 2017

Abstract: Post-transcriptional gene silencing (PTGS) is a defense mechanism that targets invading nucleic acids from endogenous (transposons) or exogenous (p... Read more »

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IPure kit
Protective vaccination and blood-stage malaria modify DNA methylati...
Published: May, 2017

Abstract: Epigenetic mechanisms such as DNA methylation are increasingly recognized to be critical for vaccination efficacy and outcome of different infectio... Read more »

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MagMeDIP kit
Novel Molecular Mechanism of Regulation of CD40 Ligand by the Trans...
Published: April, 2017

Abstract: The interaction between tumor cells and their surrounding microenvironment is essential for the growth and persistence of cancer cells. This intera... Read more »

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Bioruptor
Critical threshold levels of DNA methyltransferase 1 are required t...
Published: April, 2017

Abstract: Reversing DNA methylation abnormalities and associated gene silencing, through inhibiting DNA methyltransferases (DNMTs) is an important potential ... Read more »

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Antibody
DNA breaks and chromatin structural changes enhance the transcripti...
Published: April, 2017

Abstract: The autoimmune regulator (AIRE) protein is the key factor in thymic negative selection of autoreactive T cells by promoting the ectopic expression ... Read more »

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Antibody IP-Star Compact
The Role of S-Palmitoylation of the Human Glucocorticoid Receptor (...
Published: April, 2017

Abstract: Background: Many rapid nongenomic glucocorticoid actions are mediated by membrane-bound glucocorticoid receptors (GRs). S-palmitoylation is a lipid... Read more »

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Antibody
Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcri...
Published: April, 2017

Abstract: CD95/Fas ligand (FasL) is a cell death-promoting member of the tumor necrosis factor family with important functions in the regulation of T-cell ho... Read more »

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IPure kit
Genomic responses of mouse synovial fibroblasts during TNF-driven a...
Published: April, 2017

Abstract: OBJECTIVE: Aberrant activation of synovial fibroblasts (SFs) is a key determinant in the pathogenesis of rheumatoid arthritis (RA). We aimed to pr... Read more »

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Bioruptor ChIP-seq Antibody
H2A monoubiquitination in Arabidopsis thaliana is generally indepen...
Published: April, 2017

Abstract: BACKGROUND: Polycomb group complexes PRC1 and PRC2 repress gene expression at the chromatin level in eukaryotes. The classic recruitment model o... Read more »

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Antibody
Global analysis of H3K27me3 as an epigenetic marker in prostate can...
Published: April, 2017

Abstract: BACKGROUND: H3K27me3 histone marks shape the inhibition of gene transcription. In prostate cancer, the deregulation of H3K27me3 marks might play... Read more »

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Antibody IP-Star Compact True MicroChIP kit
Glucocorticoid receptor represses brain-derived neurotrophic factor...
Published: April, 2017

Abstract: Brain-derived neurotrophic factor (BDNF) is involved in many functions such as neuronal growth, survival, synaptic plasticity and memorization. Alt... Read more »

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ChIP-qPCR

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