Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A high-quality genome sequence of Rosa chinensis to elucidate ornam...
Published: June, 2018

Abstract: Rose is the world's most important ornamental plant, with economic, cultural and symbolic value. Roses are cultivated worldwide and sold as garden ... Read more »

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Megaruptor
MeDIP combined with in-solution targeted enrichment followed by NGS...
Published: June, 2018

Abstract: DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invas... Read more »

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iDeal Library Preparation Kit
Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB coop...
Published: June, 2018

Abstract: In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), pro... Read more »

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Antibody
Determination of the presence of 5-methylcytosine in Paramecium tet...
Published: June, 2018

Abstract: 5-methylcytosine DNA methylation regulates gene expression and developmental programming in a broad range of eukaryotes. However, its presence and ... Read more »

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Antibody
SETBP1 induces transcription of a network of development genes by a...
Published: June, 2018

Abstract: SETBP1 variants occur as somatic mutations in several hematological malignancies such as atypical chronic myeloid leukemia and as de novo germline ... Read more »

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Antibody
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedif...
Published: June, 2018

Abstract: To date, it remains largely unclear to what extent chromatin machinery contributes to the susceptibility and progression of complex diseases. Here,... Read more »

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Antibody
DNA Methylation and Regulatory Elements during Chicken Germline Ste...
Published: June, 2018

Abstract: The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell di... Read more »

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MethylCap
Immunity drives regulation in cancer through NF-κB.
Published: June, 2018

Abstract: Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to... Read more »

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Antibody
Immunity drives TET1 regulation in cancer through NF-kB
Published: June, 2018

Abstract: Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to... Read more »

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Antibody
The reference epigenome and regulatory chromatin landscape of chron...
Published: June, 2018

Abstract: Chronic lymphocytic leukemia (CLL) is a frequent hematological neoplasm in which underlying epigenetic alterations are only partially understood. H... Read more »

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Antibody
Epigenetic regulation of vascular NADPH oxidase expression and reac...
Published: June, 2018

Abstract: Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in... Read more »

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Antibody
Involvement of Epigenetic Modifications of GABAergic Interneurons i...
Published: June, 2018

Abstract: Background: Prenatal stress is considered a risk factor for anxiety disorder. Downregulation in the expression of GABAergic gene, that is, glutamic... Read more »

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MeDIP kit
Increased H3K9 methylation and impaired expression of Protocadherin...
Published: June, 2018

Abstract: Kleefstra syndrome, a disease with intellectual disability, autism spectrum disorders and other developmental defects is caused in humans by haploi... Read more »

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Antibody
Histone H3 lysine 36 methyltransferase mobilizes NER factors to reg...
Published: June, 2018

Abstract: The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA d... Read more »

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Antibody
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: June, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora of functio... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense...
Published: June, 2018

Abstract: BACKGROUND: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide m... Read more »

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HighCell ChIP kit
UTX-mediated enhancer and chromatin remodeling suppresses myeloid l...
Published: June, 2018

Abstract: The histone H3 Lys27-specific demethylase UTX (or KDM6A) is targeted by loss-of-function mutations in multiple cancers. Here, we demonstrate that U... Read more »

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Antibody
Estrogen receptor α dependent regulation of estrogen related recept...
Published: May, 2018

Abstract: BACKGROUND: Breast cancer (BC) is highly heterogeneous with ~ 60-70% of estrogen receptor positive BC patient's response to anti-hormone the... Read more »

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Antibody
The histone demethylase Phf2 acts as a molecular checkpoint to prev...
Published: May, 2018

Abstract: Aberrant histone methylation profile is reported to correlate with the development and progression of NAFLD during obesity. However, the identifica... Read more »

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Antibody
A Rapid and Robust Protocol for Reduced Representation Bisulfite Se...
Published: May, 2018

Abstract: Reduced representation bisulfite sequencing (RRBS) is one of the most comprehensive yet economic ways of mapping whole genome DNA-methylation. Here... Read more »
An improved assembly and annotation of the melon (Cucumis melo L.) ...
Published: May, 2018

Abstract: We report an improved assembly (v3.6.1) of the melon (Cucumis melo L.) genome and a new genome annotation (v4.0). The optical mapping approach allo... Read more »

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IPure kit IP-Star Compact
Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem...
Published: May, 2018

Abstract: The cell microenvironment, which is critical for stem cell maintenance, contains both cellular and non-cellular components, including sec... Read more »

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IP-Star Antibody True MicroChIP kit iDeal ChIP-seq Kit for Histones
Polycomb Repressive Complex 2 attenuates the very high expression o...
Published: May, 2018

Abstract: PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression... Read more »

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Antibody IPure kit
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: May, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Antibody
Distinct epigenetic landscapes underlie the pathobiology of pancrea...
Published: May, 2018

Abstract: Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although... Read more »

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Antibody
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018

Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »

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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Insulin promoter in human pancreatic β cells contacts diabetes susc...
Published: May, 2018

Abstract: Both type 1 and type 2 diabetes involve a complex interplay between genetic, epigenetic, and environmental factors. Our laboratory has been interes... Read more »

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IP-Star Compact Microplex Library Preparation kit True MicroChIP kit
Functional interplay between E2F7 and ribosomal rRNA gene transcrip...
Published: May, 2018

Abstract: A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. ... Read more »

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Bioruptor
Local adaptation and ecological differentiation under selection, mi...
Published: May, 2018

Abstract: How the balance between selection, migration and drift influences the evolution of local adaptation has been under intense theoretical scrutiny. Ye... Read more »

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Bioruptor
The chromatin remodeling factor SPOC1 acts as a cellular restricti...
Published: May, 2018

Abstract: The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA dam... Read more »

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Bioruptor Bioruptor Plus

Events

  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
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