Publications,References

Identification and Massively Parallel Characterization of Regulator...
Published: November, 2019

Abstract: Epigenomic regulation and lineage-specific gene expression act in concert to drive cellular differentiation, but the temporal interplay between the... Read more »

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LowCell ChIP kit IPure kit

Distinct IL-1α-responsive enhancers promote acute and coordinated c...
Published: November, 2019

Abstract: How cytokine-driven changes in chromatin topology are converted into gene regulatory circuits during inflammation still remains unclear. Here, we s... Read more »

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Antibody

Native Chromatin Proteomics Reveals a Role for Specific Nucleoporin...
Published: November, 2019

Abstract: Spatially and functionally distinct domains of heterochromatin and euchromatin play important roles in the maintenance of chromosome stability and ... Read more »

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Antibody

Epigenetic remodelling licences adult cholangiocytes for organoid f...
Published: November, 2019

Abstract: Following severe or chronic liver injury, adult ductal cells (cholangiocytes) contribute to regeneration by restoring both hepatocytes and cholangi... Read more »

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Antibody LowCell ChIP kit IPure kit

Methionine metabolism in health and cancer: a nexus of diet and pre...
Published: November, 2019

Abstract: Methionine uptake and metabolism is involved in a host of cellular functions including methylation reactions, redox maintenance, polyamine synthesi... Read more »

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Antibody IP-Star Compact

Epigenetic transgenerational inheritance of parent-of-origin alleli...
Published: October, 2019

Abstract: Epigenetic transgenerational inheritance potentially impacts disease etiology, phenotypic variation, and evolution. An increasing number of environ... Read more »

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Antibody

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Est...
Published: October, 2019

Abstract: Notwithstanding the positive clinical impact of endocrine therapies in estrogen receptor-alpha (ERα)-positive breast cancer, de novo and acqu... Read more »

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Antibody

Circulating miRNA analysis for cancer diagnostics and therapy.
Published: October, 2019

Abstract: Successful treatment of cancer depends on early diagnosis and effective monitoring of patients' response to therapy. Traditional tools based on tum... Read more »

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CATS

Obesogen effect of bisphenol S alters mRNA expression and DNA methy...
Published: October, 2019

Abstract: Environmental pollution is increasingly considered an important factor involved in the obesity incidence. Endocrine disruptors (EDs) are important ... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

TET2 Regulates the Neuroinflammatory Response in Microglia.
Published: October, 2019

Abstract: Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for microglia in neuroinflam... Read more »

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Antibody

Epigenetic down-regulation of the HIST1 locus predicts better progn...
Published: October, 2019

Abstract: BACKGROUND: The epigenetic machinery is frequently altered in acute myeloid leukemia. Focusing on cytogenetically normal (CN) AML, we previously de... Read more »

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IPure kit

Physical and functional interaction between SET1/COMPASS complex co...
Published: October, 2019

Abstract: The CFP1 CXXC zinc finger protein targets the SET1/COMPASS complex to non-methylated CpG rich promoters to implement tri-methylation of histone H3 ... Read more »

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Antibody

17-Estradiol Activates HSF1 via MAPK Signaling in ER-Positive Breas...
Published: October, 2019

Abstract: Heat Shock Factor 1 (HSF1) is a key regulator of gene expression during acute environmental stress that enables the cell survival, which is also in... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

CURLY LEAF regulates micro RNA activity by controlling ARGONAUTE 1 ...
Published: October, 2019

Abstract: CURLY LEAF (CLF) encodes the methyl-transferase sub-unit of the Polycomb Repressor Complex 2 (PRC2), which regulates the expression of target genes... Read more »

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Antibody

Genomic and phenotypic analyses of six offspring of a genome-edited...
Published: October, 2019

Abstract: Genome editing followed by reproductive cloning was previously used to produce two hornless dairy bulls. We crossed one genome-edited dairy bull, h... Read more »

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Megaruptor

Epigenomic signatures underpin the axonal regenerative ability of d...
Published: October, 2019

Abstract: Axonal injury results in regenerative success or failure, depending on whether the axon lies in the peripheral or the CNS, respectively. The presen... Read more »

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Antibody

Complete Genome Sequence of an Enterohemorrhagic Escherichia coli O...
Published: October, 2019

Abstract: We present the complete genome sequence of an enterohemorrhagic O111:H8 strain. This strain was isolated from a hemolytic-uremic syndrome patient a... Read more »

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Megaruptor

Transcriptional alterations in glioma result primarily from DNA met...
Published: October, 2019

Abstract: In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. H... Read more »

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Antibody

Programmed increases in LXRα induced by paternal alcohol use enhanc...
Published: September, 2019

Abstract: Paternally inherited alterations in epigenetic programming are emerging as relevant factors in numerous disease states, including the growth and me... Read more »

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Bioruptor Plus

SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusi...
Published: September, 2019

Abstract: Epigenetic regulators play a critical role in normal and malignant hematopoiesis. Deregulation, including epigenetic deregulation, of the gene clus... Read more »

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iDeal Library Preparation Kit

Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of...
Published: September, 2019

Abstract: During endochondral ossification, the differentiation of proliferating into hypertrophic chondrocytes is a key step determining the pace of bone fo... Read more »

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True MicroChIP kit

Assaying epigenome functions of PRMTs and their substrates.
Published: September, 2019

Abstract: Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein ... Read more »

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Antibody

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediat...
Published: September, 2019

Abstract: Acute myeloid leukemia (AML) is associated with mutations in transcriptional and epigenetic regulator genes impairing myeloid differentiation. The ... Read more »

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Antibody

Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acety...
Published: September, 2019

Abstract: Inactivating mutations of the CREBBP and EP300 acetyltransferases are among the most common genetic alterations in diffuse large B cell lymphoma (D... Read more »

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Antibody

Functional analyses of a low-penetrance risk variant rs6702619/1p21...
Published: September, 2019

Abstract: Several studies employed the genome-wide association (GWA) analysis of single-nucleotide polymorphisms (SNPs) to identify susceptibility regions in... Read more »

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Antibody

Relationship between osteoporosis and osteoarthritis based on DNA m...
Published: September, 2019

Abstract: : The aim of this study was to investigate the relationship between osteoporosis and osteoarthritis by analyzing the DNA methylation in osteoporosi... Read more »

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Antibody

Improved double-nicking strategies for COL7A1 editing by homologous...
Published: September, 2019

Abstract: Current gene editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin di... Read more »

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Antibody

Improved Double-Nicking Strategies for COL7A1-Editing by Homologous...
Published: September, 2019

Abstract: Current gene-editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin di... Read more »

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Antibody

Cooperation of cancer drivers with regulatory germline variants sha...
Published: September, 2019

Abstract: Pediatric malignancies including Ewing sarcoma (EwS) feature a paucity of somatic alterations except for pathognomonic driver-mutations that cannot... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Residual apoptotic activity of a tumorigenic p53 mutant improves ca...
Published: September, 2019

Abstract: Engineered p53 mutant mice are valuable tools for delineating p53 functions in tumor suppression and cancer therapy. Here, we have introduced the R... Read more »

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Microplex Library Preparation kit

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