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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Epigenetic Alterations in Juvenile Spondyloarthritis Patients: a Pr...
Published: May, 2019
Abstract: Juvenile spondyloarthritis (jSpA) is a complex disease with both genetic and environmental factors contributing to etiology. Multiple studies have ... Read more »
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MagMeDIP kit
Cardiac Reprogramming Factors Synergistically Activate Genome-wide ...
Published: May, 2019
Abstract: The cardiogenic transcription factors (TFs) Mef2c, Gata4, and Tbx5 can directly reprogram fibroblasts to induced cardiac-like myocytes (iCLMs), pre... Read more »
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Antibody
Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory i...
Published: May, 2019
Abstract: BACKGROUND: Rewriting of the epigenome has risen as a promising alternative to gene editing for precision medicine. In nature, epigenetic silencing... Read more »
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Antibody
Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Tra...
Published: May, 2019
Abstract: The gene regulatory network (GRN) of naive mouse embryonic stem cells (ESCs) must be reconfigured to enable lineage commitment. TCF3 sanctions rewi... Read more »
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Antibody
Guidelines for optimized gene knockout using CRISPR/Cas9
Published: May, 2019
Abstract: CRISPR/Cas9 technology has evolved as the most powerful approach to generate genetic models both for fundamental and preclinical research. Despite ... Read more »
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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors CRISPR
Interferon signature in patients with STAT1 gain-of-function mutati...
Published: May, 2019
Abstract: STAT1 gain-of-function (GOF) variants lead to defective Th17 cell development and chronic mucocutaneous candidiasis (CMC), but frequently also... Read more »
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IP-Star Compact
The Chromatin Factor HNI9 and ELONGATED HYPOCOTYL5 Maintain ROS Hom...
Published: May, 2019
Abstract: Reactive oxygen species (ROS) can accumulate in cells at excessive levels, leading to unbalanced redox states and to potential oxidative stress, wh... Read more »
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Antibody
Repression of Germline Genes in Somatic Tissues by H3K9 Dimethylat...
Published: May, 2019
Abstract: Repression of germline-promoting genes in somatic cells is critical for somatic development and function. To study how germline genes are repressed... Read more »
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IP-Star Compact
Long-range interactions between topologically associating domains s...
Published: May, 2019
Abstract: Genomic information is selectively used to direct spatial and temporal gene expression during differentiation. Interactions between topologically a... Read more »
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Antibody
Epigenetic control of the angiotensin-converting enzyme in endothel...
Published: May, 2019
Abstract: The angiotensin-converting enzyme (ACE) plays a central role in the renin-angiotensin system, which is involved in the regulation of blood pressure... Read more »
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MagMeDIP kit
Epigenetic modulation of a hardwired 3D chromatin landscape in two ...
Published: May, 2019
Abstract: The mechanisms underlying enhancer activation and the extent to which enhancer-promoter rewiring contributes to spatiotemporal gene expression are ... Read more »
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Antibody
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cel...
Published: May, 2019
Abstract: Silencing of the somatic cell type-specific genes is a critical yet poorly understood step in reprogramming. To uncover pathways that maintain cell... Read more »
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Antibody
ChIP-seq of plasma cell-free nucleosomes identifies cell-of-origin ...
Published: May, 2019
Abstract: Blood cell-free DNA (cfDNA) is derived from fragmented chromatin in dying cells. As such, it remains associated with histones that may retain the c... Read more »
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Antibody
Canonical PRC1 controls sequence-independent propagation of Polycom...
Published: April, 2019
Abstract: Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catal... Read more »
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Antibody
Genome-wide DNA methylation profiles in Tibetan and Yorkshire pigs ...
Published: April, 2019
Abstract: Background: Tibetan pigs, which inhabit the Tibetan Plateau, exhibit distinct phenotypic and physiological characteristics from those of lowland pi... Read more »
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MagMeDIP kit
P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Res...
Published: April, 2019
Abstract: DNA damage response (DDR) involves dramatic transcriptional alterations, the mechanisms of which remain ill defined. Here, we show that following g... Read more »
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Bioruptor
BRCA1 mutations attenuate super-enhancer function and chromatin loo...
Published: April, 2019
Abstract: BACKGROUND: BRCA1-associated breast cancer originates from luminal progenitor cells. BRCA1 functions in multiple biological processes, including do... Read more »
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Microplex Library Preparation kit
PML modulates H3.3 targeting to telomeric and centromeric repeats i...
Published: April, 2019
Abstract: Targeted deposition of histone variant H3.3 into chromatin is paramount for proper regulation of chromatin integrity, particularly in heterochromat... Read more »
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Antibody
Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecul...
Published: April, 2019
Abstract: Studies in vertebrates have outlined conserved molecular control of definitive endoderm (END) development. However, recent work also shows that key... Read more »
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Antibody
The Reference Genome Sequence of Scutellaria baicalensis Provides I...
Published: April, 2019
Abstract: Scutellaria baicalensis Georgi is important in Chinese traditional medicine where preparations of dried roots, "Huang Qin," are used for liver and ... Read more »
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Megaruptor
Long intergenic non-coding RNAs regulate human lung fibroblast func...
Published: April, 2019
Abstract: Phenotypic changes in lung fibroblasts are believed to contribute to the development of Idiopathic Pulmonary Fibrosis (IPF), a progressive and fata... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Defining UHRF1 Domains that Support Maintenance of Human Colon Canc...
Published: April, 2019
Abstract: UHRF1 facilitates the establishment and maintenance of DNA methylation patterns in mammalian cells. The establishment domains are defined, includin... Read more »
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Antibody
TET3 prevents terminal differentiation of adult NSCs by a non-catal...
Published: April, 2019
Abstract: Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, altho... Read more »
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Antibody
Dissecting the role of H3K27 acetylation and methylation in PRC2 me...
Published: April, 2019
Abstract: The Polycomb repressive complexes PRC1 and PRC2 act non-redundantly at target genes to maintain transcriptional programs and ensure cellular identi... Read more »
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Antibody
Essential Gene Profiles for Human Pluripotent Stem Cells Identify U...
Published: April, 2019
Abstract: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding... Read more »
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Antibody
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphoc...
Published: April, 2019
Abstract: Increased glycolysis parallels immune cell activation, but the role of pyruvate remains largely unexplored. We found that stimulation of dendritic ... Read more »
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Antibody
Identification of ADGRE5 as discriminating MYC target between Burki...
Published: April, 2019
Abstract: BACKGROUND: MYC is a heterogeneously expressed transcription factor that plays a multifunctional role in many biological processes such as cell pro... Read more »
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Antibody
A TetR-family transcription factor regulates fatty acid metabolism ...
Published: April, 2019
Abstract: Fatty acid metabolism and its regulation are known to play important roles in bacteria and eukaryotes. By contrast, although certain archaea appear... Read more »
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IPure kit
Enabling cell-type-specific behavioral epigenetics in Drosophila: a...
Published: April, 2019
Abstract: BACKGROUND: Epigenetic mechanisms play fundamental roles in brain function and behavior and stressors such as social isolation can alter animal beh... Read more »
Assessment and site-specific manipulation of DNA (hydroxy-)methylat...
Published: April, 2019
Abstract: Dynamic changes in DNA (hydroxy-)methylation are fundamental for stem cell differentiation. However, the signature of these epigenetic marks in spe... Read more »
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MagMeDIP kit

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