Alterations in the hepatocyte epigenetic landscape in steatosis. Published: July, 2023 Abstract:
Fatty liver disease or the accumulation of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellular carcinoma. Yet, little is known about ... Read more » Tags Antibody
SMYD3: a new regulator of the early steps of adipocyte differentiation Published: June, 2023 Abstract:
In obesity, adipose tissue undergoes a remodeling process characterized by increased adipocyte size (hypertrophia) and number (hyperplasia). The individual ability to tip the balance toward the hyperplastic growth, with recruitment of new fat cell... Read more » Tags Antibody
Single-cell m6A mapping in vivo using picoMeRIP-seq Published: June, 2023 Abstract:
Current N-methyladenosine (mA) mapping methods need large amounts of RNA or are limited to cultured cells. Through optimized sample recovery and signal-to-noise ratio, we developed picogram-scale mA RNA immunoprecipitation and sequencing (picoMeRI... Read more » Tags Antibody
The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cellfate. Published: May, 2023 Abstract:
Placental development relies on coordinated cell fate decisions governed by signalling inputs. However, little is known about how signalling cues are transformed into repressive mechanisms triggering lineage-specific transcriptional signatures. He... Read more » Tags Antibody
