Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

miR-30a as Potential Therapeutics by Targeting TET1 through Regulat...
Published: March, 2017

Abstract: Several recent studies have indicated that miR-30a plays critical roles in various biological processes and diseases. However, the mechanism of miR... Read more »

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Antibody
Functional variation in allelic methylomes underscores a strong gen...
Published: March, 2017

Abstract: BACKGROUND: The functional impact of genetic variation has been extensively surveyed, revealing that genetic changes correlated to phenotypes li... Read more »

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IP-Star Compact
ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a C...
Published: March, 2017

Abstract: We investigated the relationship among ERK signaling, histone modifications, and transcription factor activity, focusing on the ERK-regulated terna... Read more »

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Antibody
First landscape of binding to chromosomes for a domesticated marine...
Published: March, 2017

Abstract: Setmar is a 3-exons gene coding a SET domain fused to a Hsmar1 transposase. Its different transcripts theoretically encode 8 isoforms with SET moie... Read more »

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Microplex Library Preparation kit
Connexin43 controls N-cadherin transcription during collective cell...
Published: March, 2017

Abstract: Connexins are the primary components of gap junctions, providing direct links between cells in many physiological processes, including cell migrati... Read more »

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Antibody
Crebbp loss cooperates with Bcl2 over-expression to promote lymphom...
Published: March, 2017

Abstract: CREBBP is targeted by inactivating mutations in follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). Here, we provide evidence from ... Read more »

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ChIP-seq IP-Star IP-Star Compact Microplex Library Preparation kit
Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resi...
Published: March, 2017

Abstract: Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnor... Read more »

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Antibody
Krüppel-like transcription factor KLF10 suppresses TGFβ-induced epi...
Published: March, 2017

Abstract: TGFβ-SMAD signaling exerts a contextual effect that suppresses malignant growth early in epithelial tumorigenesis but promotes metastasis at l... Read more »

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Antibody
Assessing histone demethylase inhibitors in cells: lessons learned
Published: March, 2017

Abstract: Background Histone lysine demethylases (KDMs) are of interest as drug targets due to their regulatory roles in chromatin organization and their ... Read more »

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Antibody
Conserved effect of aging on DNA methylation and association with E...
Published: February, 2017

Abstract: In humans, DNA methylation at specific CpG sites can be used to estimate the 'epigenetic clock', a biomarker of aging and health. The mechanisms th... Read more »

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MethylCap
Aorta macrophage inflammatory and epigenetic changes in a murine mo...
Published: February, 2017

Abstract: Obstructive sleep apnea (OSA) affects 8-10% of the population, is characterized by chronic intermittent hypoxia (CIH), and causally associates with... Read more »

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Antibody Microplex Library Preparation kit True MicroChIP kit
Type I interferon-enhanced IL-10 expression in human CD4 T cells is...
Published: February, 2017

Abstract: Type I IFN can exert pro- and anti-inflammatory activities in the immune system. Here, we have investigated the mechanism by which IFN-α enha... Read more »

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IPure kit
Inactivation of Lsd1 triggers senescence in trophoblast stem cells ...
Published: February, 2017

Abstract: Coordination of energy metabolism is essential for homeostasis of stem cells, whereas an imbalance in energy homeostasis causes disease and acceler... Read more »

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IP-Star Compact
An endoparasitoid wasp influences host DNA methylation
Published: February, 2017

Abstract: Parasitism by endoparasitoid wasps changes the expression of various host genes, and alters host immune and developmental processes. However, it is... Read more »
Intestinal NCoR1, a regulator of epithelial cell maturation, contro...
Published: February, 2017

Abstract: Severe neonatal hyperbilirubinemia (SNH) and the onset of bilirubin encephalopathy and kernicterus result in part from delayed expression of UDP-gl... Read more »

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Microplex Library Preparation kit
H3.Y discriminates between HIRA and DAXX chaperone complexes and re...
Published: February, 2017

Abstract: Histone chaperones prevent promiscuous histone interactions before chromatin assembly. They guarantee faithful deposition of canonical histones and... Read more »

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Antibody Microplex Library Preparation kit
Overexpression of LINE-1 Retrotransposons in Autism Brain
Published: February, 2017

Abstract: Long interspersed nuclear elements-1 (LINE-1 or L1) are mobile DNA sequences that are capable of duplication and insertion (retrotransposition) wit... Read more »

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MagMeDIP kit
The Drosophila speciation factor HMR localizes to genomic insulator...
Published: February, 2017

Abstract: Hybrid incompatibility between Drosophila melanogaster and D. simulans is caused by a lethal interaction of the proteins encoded by the Hmr and Lhr... Read more »

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Microplex Library Preparation kit
RNF40 regulates gene expression in an epigenetic context-dependent ...
Published: February, 2017

Abstract: BACKGROUND: Monoubiquitination of H2B (H2Bub1) is a largely enigmatic histone modification that has been linked to transcriptional elongation. B... Read more »

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Antibody
Jmjd2c/Kdm4c facilitates the assembly of essential enhancer-protein...
Published: February, 2017

Abstract: Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exi... Read more »

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Antibody
Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) o...
Published: February, 2017

Abstract: Both Reelin (RELN) and glutamate decarboxylase 67 (GAD1) have been implicated in the pathophysiology of Autism Spectrum Disorders (ASD). We have pr... Read more »

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Antibody
The non-coding variant rs1800734 enhances DCLK3 expression through ...
Published: February, 2017

Abstract: Genome-wide association studies have identified a great number of non-coding risk variants for colorectal cancer (CRC). To date, the majority of th... Read more »

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Antibody
Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27...
Published: February, 2017

Abstract: Although Men1 is a well-known tumour suppressor gene, little is known about the functions of Menin, the protein it encodes for. Since few years, nu... Read more »

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Antibody
Foxa2, a novel protein partner of tumour suppressor menin, is dereg...
Published: February, 2017

Abstract: Foxa2, known as one of the pioneer factors, plays a crucial role in islet development and endocrine functions. Its expression and biological functi... Read more »
A novel DLX3-PKC integrated signaling network drives keratinocyte d...
Published: February, 2017

Abstract: Epidermal homeostasis relies on a well-defined transcriptional control of keratinocyte proliferation and differentiation, which is critical to prev... Read more »

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Antibody
H3K23me1 is an evolutionarily conserved histone modification associ...
Published: February, 2017

Abstract: Amino-terminal tails of histones are targets for diverse post-translational modifications whose combinatorial action may constitute a code that wil... Read more »

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Antibody IPure kit
Intergenerational Transmission of Enhanced Seizure Susceptibility a...
Published: February, 2017

Abstract: Environmental exposure early in development plays a role in susceptibility to disease in later life. Here, we demonstrate that prolonged febrile se... Read more »

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Antibody
Genome-wide analyses of four major histone modifications in Arabido...
Published: February, 2017

Abstract: Background Hybrid vigour (heterosis) has been used for decades in cropping agriculture, especially in the production of maize and rice, because ... Read more »

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Antibody
Heat Shock Induced Phosphorylation of TAR DNA Binding Protein 43 (T...
Published: February, 2017

Abstract: TAR DNA binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA process... Read more »
Faithful SGCE imprinting in iPSC-derived cortical neurons: an endog...
Published: February, 2017

Abstract: In neuropathology research, induced pluripotent stem cell (iPSC)-derived neurons are considered a tool closely resembling the patient brain. Albeit... Read more »

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Premium Bisulfite Kit

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