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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The CCAAT box in the proximal SERCA2 gene promoter regulates basal ...
Published: September, 2017
Abstract: The cardiac sarco/endoplasmic reticulum Ca2+-ATPase-2a (SERCA2a) is vital for the correct handling of calcium concentration in cardiomyocytes. Rece... Read more »
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate ...
Published: September, 2017
Abstract: Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition, and a ca... Read more »
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ChIP-seq
FOXF1 transcription factor promotes lung regeneration after partial...
Published: September, 2017
Abstract: FOXF1, a member of the forkhead box family of transcription factors, has been previously shown to be critical for lung development, homeostasis, an... Read more »
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IP-Star Compact
DNA methylation of intragenic CpG islands depends on their transcri...
Published: September, 2017
Abstract: The human genome contains ∼30,000 CpG islands (CGIs). While CGIs associated with promoters nearly always remain unmethylated, many of the ∼... Read more »
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Antibody
Distinct Circadian Signatures in Liver and Gut Clocks Revealed by K...
Published: September, 2017
Abstract: The circadian clock orchestrates rhythms in physiology and behavior, allowing organismal adaptation to daily environmental changes. While food inta... Read more »
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Antibody
Gene body methylation is involved in coarse genome-wide adjustment ...
Published: September, 2017
Abstract: Gene body methylation (GBM) is a taxonomically widespread epigenetic modification of the DNA the function of which remains unclear 1,2. GBM is bimo... Read more »
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MethylCap
The Hox proteins Ubx and AbdA collaborate with the transcription pa...
Published: September, 2017
Abstract: In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulatio... Read more »
A lipodystrophy-causing lamin A mutant alters conformation and epig...
Published: September, 2017
Abstract: Mutations in the Lamin A/C (LMNA) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic s... Read more »
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Antibody
Chromosome contacts in activated T cells identify autoimmune diseas...
Published: September, 2017
Abstract: BACKGROUND: Autoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. ... Read more »
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IP-Star Antibody
Transcription of synaptic plasticity-related genes in patients with...
Published: September, 2017
Abstract: Objective: To investigate DNA methylation and hydroxymethylation in patients with somnipathy combined with type 2 diabetes, and to explore the effe... Read more »
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MeDIP kit
High-Resolution Chromatin Immunoprecipitation: ChIP-Sequencing
Published: September, 2017
Abstract: Chromatin immunoprecipitation (ChIP) coupled with next-generation sequencing (NGS) is widely used for studying the nucleoprotein components that ar... Read more »
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IPure kit
Epigenome profiling and editing of neocortical progenitor cells dur...
Published: September, 2017
Abstract: The generation of neocortical neurons from neural progenitor cells (NPCs) is primarily controlled by transcription factors binding to DNA in the co... Read more »
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LowCell ChIP kit IPure kit Microplex Library Preparation kit
Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-O...
Published: September, 2017
Abstract: Root growth is modulated by environmental factors and depends on cell production in the root meristem (RM). New cells in the meristem are generated... Read more »
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IPure kit
SMC Progressively Aligns Chromosomal Arms in Caulobacter crescentus...
Published: August, 2017
Abstract: The structural maintenance of chromosomes (SMC) complex plays an important role in chromosome organization and segregation in most living organisms... Read more »
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ChIP-qPCR
Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits in...
Published: August, 2017
Abstract: Abstract Problem Heightened maternal stress affects trophoblast function and increases risk for adverse pregnancy outcomes. Methods of Stu... Read more »
Epigenetic variation between urban and rural populations of Darwin'...
Published: August, 2017
Abstract: Background The molecular basis of evolutionary change is assumed to be genetic variation. However, growing evidence suggests that epigenetic m... Read more »
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Antibody
Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichme...
Published: August, 2017
Abstract: Background Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure... Read more »
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MagMeDIP kit
A lncRNA fine tunes the dynamics of a cell state transition involvi...
Published: August, 2017
Abstract: Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated f... Read more »
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Antibody
Myc Regulates Chromatin Decompaction and Nuclear Architecture durin...
Published: August, 2017
Abstract: 50 years ago, Vincent Allfrey and colleagues discovered that lymphocyte activation triggers massive acetylation of chromatin. However, the molecula... Read more »
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Antibody
Transcriptome sequencing in pediatric acute lymphoblastic leukemia ...
Published: August, 2017
Abstract: BACKGROUND: Structural chromosomal rearrangements that lead to expressed fusion genes are a hallmark of acute lymphoblastic leukemia (ALL). In t... Read more »
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Microplex Library Preparation kit
Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in hum...
Published: August, 2017
Abstract: Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (... Read more »
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Antibody
High Resolution Mapping of Chromatin Conformation in Cardiac Myocyt...
Published: August, 2017
Abstract: Background -Cardiovascular disease is associated with epigenomic changes in the heart, however the endogenous structure of cardiac myocyte chromati... Read more »
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Antibody
Circadian Reprogramming in the Liver Identifies Metabolic Pathways ...
Published: August, 2017
Abstract: The process of aging and circadian rhythms are intimately intertwined, but how peripheral clocks involved in metabolic homeostasis contribute to ag... Read more »
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Antibody
DNMT3B overexpression contributes to aberrant DNA methylation and M...
Published: August, 2017
Abstract: Aberrant DNA methylation is a hallmark of cancer. However, our understanding of how tumor cell-specific DNA methylation patterns are established an... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-...
Published: August, 2017
Abstract: BACKGROUND: The epithelial-to-mesenchymal transition (EMT) enables epithelial cancer cells to acquire mesenchymal features and contributes to me... Read more »
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Antibody
Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methy...
Published: August, 2017
Abstract: During cellular differentiation, genes important for differentiation are expected to be silent in stem/progenitor cells yet can be readily activate... Read more »
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Microplex Library Preparation kit
Coordinate Regulation of TET2 and EBNA2 Control DNA Methylation Sta...
Published: August, 2017
Abstract: Epstein-Barr Virus (EBV) latency and its associated carcinogenesis are regulated by dynamic changes in DNA methylation of both virus and host genom... Read more »
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MagMeDIP kit
The RPMI-1640 vitamin mixture promotes bovine blastocyst developmen...
Published: August, 2017
Abstract: Diverse environmental conditions surrounding preimplantation embryos, including available nutrients, affect their metabolism and development in bot... Read more »
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True MicroChIP kit
Maternal obesity programs increased leptin gene expression in rat m...
Published: August, 2017
Abstract: OBJECTIVE: According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates pred... Read more »
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Antibody
A novel FOXA1/ESR1 interacting pathway: A study of Oncomine™ breast...
Published: August, 2017
Abstract: Forkhead box protein A1 (FOXA1) is essential for the growth and differentiation of breast epithelium, and has a favorable outcome in breast cancer ... Read more »
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Antibody

Events

  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
 See all events

 

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