Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in ...
Published: July, 2015

Abstract: Endothelial to mesenchymal transition (EndMT) was originally described in heart development where the endocardial endothelial cells that line the a... Read more »
Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tum...
Published: July, 2015

Abstract: Sox9 is a transcription factor expressed in most solid tumors. However, the molecular mechanisms underlying Sox9 function during tumorigenesis rema... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq
DNA methylation directs functional maturation of pancreatic β cells
Published: July, 2015

Abstract: Pancreatic β cells secrete insulin in response to postprandial increases in glucose levels to prevent hyperglycemia and inhibit insulin secret... Read more »

Tags
Antibody
Regulation of the expression of claudin 23 by the enhancer of zeste...
Published: July, 2015

Abstract: Altered epigenetic mechanisms, similar to gene mutations, contribute to the pathogenesis and molecular heterogeneity of neoplasms, including colore... Read more »

Tags
Bioruptor Chromatin Shearing Bioruptor Plus
Transcription factor p63 bookmarks and regulates dynamic enhancers ...
Published: July, 2015

Abstract: The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates ep... Read more »

Tags
Antibody
GCDCA down-regulates gene expression by increasing Sp1 binding to t...
Published: July, 2015

Abstract: During the course of cholestatic liver diseases, the toxic effect of bile acids accumulation has been related to the decreased expression of endoth... Read more »

Tags
Bioruptor Cell Lysis
An Insulator Element Located at the Cyclin B1 Interacting Protein 1...
Published: June, 2015

Abstract: Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by ... Read more »

Tags
LowCell ChIP kit
Histone H3.3 is required for endogenous retroviral element silencin...
Published: June, 2015

Abstract: Transposable elements comprise roughly 40% of mammalian genomes. They have an active role in genetic variation, adaptation and evolution through th... Read more »

Tags
Bioruptor Chromatin Shearing
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively rep...
Published: June, 2015

Abstract: The chromatin-modifying enzyme lysine-specific demethylase 1, KDM1A/LSD1 is involved in maintaining the undifferentiated, malignant phenotype of ne... Read more »

Tags
Bioruptor Chromatin Shearing
Cistrome of the aldosterone-activated mineralocorticoid receptor in...
Published: June, 2015

Abstract: Aldosterone exerts its effects mainly by activating the mineralocorticoid receptor (MR), a transcription factor that regulates gene expression thro... Read more »

Tags
HighCell ChIP kit
Disruption of DNA-methylation-dependent long gene repression in Ret...
Published: June, 2015

Abstract: Disruption of the MECP2 gene leads to Rett syndrome (RTT), a severe neurological disorder with features of autism. MECP2 encodes a methyl-DNA-bindi... Read more »
Regulation of Hox orthologues in the oyster Crassostrea gigas evide...
Published: June, 2015

Abstract: DNA methylation within promoter regions (PRDM) controls vertebrate early gene transcription and thereby development, but is neglected outside this ... Read more »

Tags
Premium Bisulfite Kit
Concurrent whole-genome haplotyping and copy-number profiling of si...
Published: June, 2015

Abstract: Methods for haplotyping and DNA copy-number typing of single cells are paramount for studying genomic heterogeneity and enabling genetic diagnosis.... Read more »

Tags
DNA shearing Bioruptor
Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates w...
Published: June, 2015

Abstract: Pathologic c-Myc expression is frequently detected in human cancers, including Merkel cell carcinoma (MCC), an aggressive skin cancer with no cure ... Read more »

Tags
Bioruptor Chromatin Shearing
Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postm...
Published: June, 2015

Abstract: AIM: In nondividing neurons examine the role of Gadd45b in active 5-methylcytosine (5MC) and 5-hydroxymethylcytosine (5HMC) removal at a gene promo... Read more »

Tags
Antibody
Active human nucleolar organizer regions are interspersed with inac...
Published: June, 2015

Abstract: AIM: The synthesis of rRNA is a key determinant of normal and malignant cell growth and subject to epigenetic regulation. Yet, the epigenomic fe... Read more »

Tags
Antibody 5mC (C15200081)
Citrate modulates lipopolysaccharide-induced monocyte inflammatory ...
Published: June, 2015

Abstract: Citrate, a central component of cellular metabolism, is a widely used anti-coagulant due to its ability to chelate calcium. Adenosine triphosphate ... Read more »

Tags
Antibody LowCell ChIP kit H3K9ac (C15200185)
Gene chip analysis of Arabidopsis thaliana genomic DNA methylation ...
Published: June, 2015

Abstract: OBJECTIVES: To examine the effects of carbendazim on Arabidopsis genomic DNA methylation and gene expression. RESULTS: Carbendazim caused widesprea... Read more »

Tags
DNA shearing Bioruptor Antibody
Yap7 is a transcriptional repressor of nitric oxide oxidase in yeas...
Published: June, 2015

Abstract: Flavohemoglobins are the main detoxifiers of nitric oxide (NO) in bacteria and fungi and are induced in response to nitrosative stress. In fungi, t... Read more »

Tags
Bioruptor Chromatin Shearing
Transcription of Nrdp1 by the androgen receptor is regulated by nuc...
Published: June, 2015

Abstract: Prostate cancer (PCa) progression is regulated by the androgen receptor (AR); however, patients undergoing androgen-deprivation therapy (ADT) for d... Read more »

Tags
Bioruptor Chromatin Shearing
Proteomic analysis of the herpes simplex virus 1 virion protein 16 ...
Published: June, 2015

Abstract: The herpes simplex virus 1 virion protein 16 (VP16) tegument protein forms a transactivation complex with the cellular proteins host cell factor 1 ... Read more »

Tags
Bioruptor
A SNP in the HTT promoter alters NF-κB binding and is a bidirection...
Published: June, 2015

Abstract: Cis-regulatory variants that alter gene expression can modify disease expressivity, but none have previously been identified in Huntington disease ... Read more »

Tags
Bioruptor Chromatin Shearing HighCell ChIP kit
A localized nucleolar DNA damage response facilitates recruitment o...
Published: June, 2015

Abstract: DNA double-strand breaks (DSBs) are repaired by two main pathways: nonhomologous end-joining and homologous recombination (HR). Repair pathway choi... Read more »

Tags
Antibody CRISPR Cas9 (C15200203)
Allele-specific binding of ZFP57 in the epigenetic regulation of im...
Published: May, 2015

Abstract: BACKGROUND: Selective maintenance of genomic epigenetic imprints during pre-implantation development is required for parental origin-specific ex... Read more »

Tags
Antibody
The transcriptional PPARβ/δ network in human macrophages defines a ...
Published: May, 2015

Abstract: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a lipid ligand-inducible transcription factor with established metabolic functions, whe... Read more »

Tags
Microplex Library Preparation kit
Th2 Cytokines Augment IL-31/IL-31RA Interactions via STAT6-dependen...
Published: May, 2015

Abstract: Interleukin 31 receptor α (IL-31RA) is a novel Type I cytokine receptor that pairs with oncostatin M receptor to mediate IL-31 signaling. Binding o... Read more »

Tags
Bioruptor Chromatin Shearing
The N-terminal Set-β Protein Isoform Induces Neuronal Death.
Published: May, 2015

Abstract: Set-β protein plays different roles in neurons, but the diversity of Set-β neuronal isoforms and their functions have not been characterized. The e... Read more »

Tags
Bioruptor Cell Lysis
Opposing role for Egr3 in nucleus accumbens cell subtypes in cocain...
Published: May, 2015

Abstract: An imbalance in molecular signaling cascades and transcriptional regulation in nucleus accumbens (NAc) medium spiny neuron (MSN) subtypes, those en... Read more »

Tags
Bioruptor Chromatin Shearing
Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Ro...
Published: May, 2015

Abstract: The histone variant macroH2A (mH2A) has been implicated in transcriptional repression, but the molecular mechanisms that contribute to global mH2A-... Read more »

Tags
Antibody
Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory gene...
Published: May, 2015

Abstract: The glucocorticoid (GC) receptor (GR) and Kruppel-like factor Klf4 are transcription factors that play major roles in skin homeostasis. However, wh... Read more »

Tags
Bioruptor Chromatin Shearing

Events

  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
 See all events

 


       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy