Publications,References

Functional characterization of the hGRαT556I causing Chrousos syndrome
Published: January, 2016

Abstract: BACKGROUND: Chrousos syndrome is a rare pathologic condition characterized by generalized, partial resistance of target tissues to glucocorticoids... Read more »

Tags
Antibody

DNA methylation in an engineered heart tissue model of cardiac hype...
Published: January, 2016

Abstract: DNA methylation affects transcriptional regulation and constitutes a drug target in cancer biology. In cardiac hypertrophy, DNA methylation may con... Read more »

Tags
MethylCap

MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation...
Published: January, 2016

Abstract: Protein kinase C δ (PKCδ) and p38δ are key proteins in a cascade that stimulates keratinocyte differentiation. This cascade activ... Read more »

Tags
LowCell ChIP kit

Transducin-like enhancer of split-1 is expressed and functional in ...
Published: December, 2015

Abstract: Macrophages display heterogeneous phenotypes, including the classical M1 proinflammatory and the alternative M2 anti-inflammatory polarization stat... Read more »

Tags
Bioruptor Chromatin Shearing Article alert

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through...
Published: December, 2015

Abstract: Targeted therapies designed to exploit specific molecular pathways in aggressive cancers are an exciting area of current research. Mixed Lineage Le... Read more »

Tags
Antibody

Epigenome-wide effects of vitamin D and their impact on the transcr...
Published: December, 2015

Abstract: The physiological functions of vitamin D are mediated by its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) activating the transcription ... Read more »

Tags
Bioruptor Article alert

Standardizing chromatin research: a simple and universal method for...
Published: December, 2015

Abstract: Here we demonstrate that harmonization of ChIP-seq workflows across cell types and conditions is possible when obtaining chromatin from proper... Read more »

Tags
Bioruptor H3K4me3 (C15410003) IP-Star Compact H3K27me3 (C15410195) Article alert

cChIP-seq: a robust small-scale method for investigation of histone...
Published: December, 2015

Abstract: Background ChIP-seq is highly utilized for mapping histone modifications that are informative about gene regulation and genome annotations. For ... Read more »

Tags
Antibody

Embryonic transcription is controlled by maternally defined chromat...
Published: December, 2015

Abstract: Histone-modifying enzymes are required for cell identity and lineage commitment, however little is known about the regulatory origins of the epigen... Read more »

Tags
Antibody

Reversion to an embryonic alternative splicing program enhances leu...
Published: December, 2015

Abstract: Formative research suggests that a human embryonic stem cell-specific alternative splicing gene regulatory network, which is repressed by Musclebli... Read more »

Tags
Antibody

Germline organization in Strongyloides nematodes reveals alternativ...
Published: December, 2015

Abstract: Nematodes of the genus Strongyloides are important parasites of vertebrates including man. Currently, little is known about their germline organiza... Read more »

Tags
Antibody

Maternal immune activation induces GAD1 and GAD2 promoter remodelin...
Published: December, 2015

Abstract: Maternal infection during pregnancy increases the risk of neurodevelopmental disorders in the offspring. In addition to its influence on other neur... Read more »

Tags
MagMeDIP kit

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Ly...
Published: December, 2015

Abstract: The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted gene... Read more »

Tags
Antibody

Valproic acid exposure leads to upregulation and increased promoter...
Published: December, 2015

Abstract: Valproic acid (VPA) is a widely used antiepileptic drug and first-line treatment in bipolar disorder, although the mechanisms underlying its therap... Read more »

DNA methylation profiling: comparison of genome-wide sequencing met...
Published: December, 2015

Abstract: AIMS: To compare the performance of four sequence-based and one microarray methods for DNA methylation profiling. METHODS: DNA from two cell l... Read more »

Tags
MagMeDIP kit Antibody 5mC (C15200081)

Methionine-dependent histone methylation at developmentally importa...
Published: December, 2015

Abstract: The involvement of specific nutrients in epigenetic gene regulation is a possible mechanism underlying nutrition-directed phenotypic alteration. Ho... Read more »

Tags
True MicroChIP kit

A highly conserved NF-κB-responsive enhancer is critical for thymic...
Published: December, 2015

Abstract: Autoimmune regulator (Aire) has a unique expression pattern in thymic medullary epithelial cells (mTECs), in which it plays a critical role in the ... Read more »

Tags
Antibody IP-Star Compact

Oxidative DNA damage in mouse sperm chromosomes: Size matters.
Published: December, 2015

Abstract: Normal embryo and foetal development as well as the health of the progeny are mostly dependent on gamete nuclear integrity. In the present study, i... Read more »

Tags
Antibody

Transient generalized glucocorticoid hypersensitivity
Published: December, 2015

Abstract: BACKGROUND: Transient generalized glucocorticoid hypersensitivity is a rare disorder characterized by increased tissue sensitivity to glucocortico... Read more »

Tags
Antibody

The Cytoplasmic Region of Plasmodium falciparum SURFIN4.2 Is Requir...
Published: December, 2015

Abstract: Background: Plasmodium, the causative agent of malaria, exports many proteins to the surface of the infected red blood cell (iRBC) in order to mo... Read more »

Tags
Antibody

Dynamic changes in histone modifications precede de novo DNA methyl...
Published: December, 2015

Abstract: Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in... Read more »

Tags
Antibody True MicroChIP kit

Brg1 coordinates multiple processes during retinogenesis and is a t...
Published: December, 2015

Abstract: Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiat... Read more »

Tags
Antibody

Glucocorticoid receptor and nuclear factor kappa-b affect three-dim...
Published: December, 2015

Abstract: BACKGROUND: The impact of signal-dependent transcription factors, such as glucocorticoid receptor and nuclear factor kappa-b, on the three-dimen... Read more »

Tags
Antibody

Epigenetic priming of inflammatory response genes by high glucose i...
Published: November, 2015

Abstract: Cellular metabolism confers wide-spread epigenetic modifications required for regulation of transcriptional networks that determine cellular states... Read more »

Tags
Antibody

Evidence for Epigenetic Regulation of Pro-Inflammatory Cytokines, I...
Published: November, 2015

Abstract: While Post Traumatic Stress Disorder (PTSD) is associated with immune dysfunction, the underlying mechanisms remain unclear. Studies suggest a role... Read more »

Tags
MagMeDIP kit Article alert

Pyruvate kinase isoform switching and hepatic metabolic reprogrammi...
Published: November, 2015

Abstract: The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) elicits dose-dependent hepatotoxicity that includes fat accumulation, infl... Read more »

Tags
Microplex Library Preparation kit Article alert

Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses...
Published: November, 2015

Abstract: Oct-1 (POU2f1) and Oct-2 (POU2f2) are members of the POU family of transcription factors. They recognize the same DNA sequence but fulfil distinct ... Read more »

Tags
Chromatin Shearing

Hepatic DNA hydroxymethylation is site-specifically altered by chro...
Published: November, 2015

Abstract: PURPOSE: Global DNA hydroxymethylation is markedly decreased in human cancers, including hepatocellular carcinoma, which is associated with chro... Read more »

Selective targeting of the BRG/PB1 bromodomains impairs embryonic a...
Published: November, 2015

Abstract: Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene tr... Read more »

Tags
Antibody

Occupancy of RNA Polymerase II Phosphorylated on Serine 5 (RNAP S5P...
Published: November, 2015

Abstract: Regulation of gene transcription in varicella-zoster virus (VZV), a ubiquitous human neurotropic alphaherpesvirus, requires coordinated binding of ... Read more »

Tags
Antibody

Publications

Events