Publications,References

Progressive Chromatin Condensation and H3K9 Methylation Regulate th...
Published: November, 2015

Abstract: Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes a... Read more »

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IP-Star Compact

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancer...
Published: November, 2015

Abstract: Histone H3K36 trimethylation (H3K36me3) is frequently lost in multiple cancer types, identifying it as an important therapeutic target. Here we ide... Read more »

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Antibody

Complete Genome Sequences of Four Escherichia coli ST95 Isolates fr...
Published: November, 2015

Abstract: Finished genome sequences are presented for four Escherichia coli strains isolated from bloodstream infections at San Francisco General Hospital. T... Read more »

CRISPR-Mediated Gene Targeting of Human Induced Pluripotent Stem Cells
Published: November, 2015

Abstract: CRISPR/Cas9 nuclease systems can create double-stranded DNA breaks at specific sequences to efficiently and precisely disrupt, excise, mutate, inse... Read more »

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Antibody

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Te...
Published: November, 2015

Abstract: Molecular mechanisms underlying terminal differentiation of B cells into plasma cells are major determinants of adaptive immunity but remain only p... Read more »

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Antibody

The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cyc...
Published: November, 2015

Abstract: Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result ... Read more »

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Antibody

Spatial Interplay between Polycomb and Trithorax Complexes Controls...
Published: November, 2015

Abstract: Trithorax group (TrxG) and Polycomb group (PcG) proteins are two mutually antagonistic chromatin modifying complexes, however, how they together me... Read more »

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Antibody

Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Pre...
Published: November, 2015

Abstract: Genetic and epigenetic alterations have been identified as to contribute directly or indirectly to the generation of transitional cell carcinoma of... Read more »

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Antibody

HNF1β drives glutathione (GSH) synthesis underlying intrinsic carbo...
Published: October, 2015

Abstract: Chemoresistance to platinum-based antineoplastic agents is a consistent feature among ovarian carcinomas; however, whereas high-grade serous carcin... Read more »

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Bioruptor Article alert

NeuroD1 reprograms chromatin and transcription factor landscapes to...
Published: October, 2015

Abstract: Abstract Cell fate specification relies on the action of critical transcription factors that become available at distinct stages of embryonic deve... Read more »

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Bioruptor Chromatin Shearing Bioruptor Plus

Epigenetic role of CCAAT box-binding transcription factor NF-Y on I...
Published: October, 2015

Abstract: Nuclear factor Y (NF-Y) is a histone substitute protein that specifically binds to the CCAAT box of the target genes and thereby promotes their reg... Read more »

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Article alert

A gene expression signature identifying transient DNMT1 depletion a...
Published: October, 2015

Abstract: Many human tumors show aberrant activation of a group of germline-specific genes, termed cancer-germline (CG) genes, several of which appear to exe... Read more »

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Antibody Article alert

Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Do...
Published: October, 2015

Abstract: α-synuclein, a protein enriched in Lewy bodies and highly implicated in neurotoxicity in Parkinson's disease, is distributed both at nerve te... Read more »

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Antibody

Optimized method for methylated DNA immuno-precipitation
Published: October, 2015

Abstract: Methylated DNA immunoprecipitation (MeDIP) is one of the most widely used methods to evaluate DNA methylation on a whole genome scale, and involves... Read more »

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Antibody

Loss of EZH2 results in precocious mammary gland development and ac...
Published: October, 2015

Abstract: Establishment and differentiation of mammary alveoli during pregnancy are controlled by prolactin through the transcription factors STAT5A and STAT... Read more »

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Antibody

A geminivirus-based guide RNA delivery system for CRISPR/Cas9 media...
Published: October, 2015

Abstract: CRISPR/Cas has emerged as potent genome editing technology and has successfully been applied in many organisms, including several plant species. Ho... Read more »

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Antibody CRISPR Cas9 (C15200203)

The genetic association of RUNX3 with ankylosing spondylitis can be...
Published: October, 2015

Abstract: The authors sought to identify the functional basis for the genetic association of single nucleotide polymorphisms (SNP), upstream of the RUNX3 pro... Read more »

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Antibody Article alert

VEGF-mediated cell survival in non-small-cell lung cancer: implicat...
Published: October, 2015

Abstract: AIMS: To evaluate the potential therapeutic utility of histone deacetylase inhibitors (HDACi) in targeting VEGF receptors in non-small-cell lung... Read more »

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Antibody

Loss of BAP1 function leads to EZH2-dependent transformation
Published: October, 2015

Abstract: The tumor suppressors BAP1 and ASXL1 interact to form a polycomb deubiquitinase complex that removes monoubiquitin from histone H2A lysine 119 (H2A... Read more »

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IP-Star Compact

ClpX stimulates the mitochondrial unfolded protein response (UPRmt)...
Published: October, 2015

Abstract: Proteostasis is crucial for life and maintained by cellular chaperones and proteases. One major mitochondrial protease is the ClpXP complex, which ... Read more »

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Antibody

Arabidopsis CMT3 activity is positively regulated by AtSIZ1-mediate...
Published: October, 2015

Abstract: The activities of mammalian DNA and histone methyltransferases are regulated by post-translational modifications such as phosphorylation and sumoyl... Read more »

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Antibody

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in L...
Published: October, 2015

Abstract: Aberrant DNA methylation is a hallmark of cancer but mechanisms contributing to the abnormality remain elusive. We have previously shown that ∆DNMT... Read more »

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MethylCap

Disruption of KMT2D perturbs germinal center B cell development and...
Published: October, 2015

Abstract: Mutations in the gene encoding the KMT2D (or MLL2) methyltransferase are highly recurrent and occur early during tumorigenesis in diffuse large B c... Read more »

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Antibody

Polycomb repressive complex PRC1 spatially constrains the mouse emb...
Published: October, 2015

Abstract: The Polycomb repressive complexes PRC1 and PRC2 maintain embryonic stem cell (ESC) pluripotency by silencing lineage-specifying developmental regul... Read more »

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Antibody

The mycotoxin aflatoxin B1 stimulates Epstein–Barr virus-induced B-...
Published: September, 2015

Abstract: Although Epstein–Barr virus (EBV) infection is widely distributed, certain EBV-driven malignancies are geographically restricted. EBV-associa... Read more »

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Article alert

Assessment of global and gene-specific DNA methylation in rat liver...
Published: September, 2015

Abstract: Altered expression of tumor suppressor genes and oncogenes, which is regulated in part at the level of DNA methylation, is an important event invol... Read more »

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Article alert

Endothelial Msx1 transduces hemodynamic changes into an arteriogeni...
Published: September, 2015

Abstract: Collateral remodeling is critical for blood flow restoration in peripheral arterial disease and is triggered by increasing fluid shear stress in pr... Read more »

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Antibody

Regulatory role of PAK1 and CtBP1 in muscle chromatin
Published: September, 2015

Abstract: Researchers in this article showed that the co-repressor CtBP1 is present on the myogenin promoter with repressive histone marks. They found that p... Read more »

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Article alert

Deep sequencing and de novo assembly of the mouse oocyte transcript...
Published: September, 2015

Abstract: BACKGROUND: Previously, a role was demonstrated for transcription in the acquisition of DNA methylation at imprinted control regions in oocytes.... Read more »

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Antibody

The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replicatio...
Published: September, 2015

Abstract: Human papillomaviruses (HPV) regulate their differentiation-dependent life cycles by activating a number of cellular pathways, such as the DNA dama... Read more »

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Article alert

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