Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

RecG Directs DNA Synthesis during Double-Strand Break Repair
Published: February, 2016

Abstract: Homologous recombination provides a mechanism of DNA double-strand break repair (DSBR) that requires an intact, homologous template for DNA synthes... Read more »

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Bioruptor Chromatin Shearing Article alert
A genome-wide search for eigenetically regulated genes in zebra fin...
Published: February, 2016

Abstract: Learning and memory formation are known to require dynamic CpG (de)methylation and gene expression changes. Here, we aimed at establishing a genome... Read more »

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MethylCap
Differential Expression of Genes and DNA Methylation associated wit...
Published: February, 2016

Abstract: Previously, long-term effects on body weight and reproductive performance have been demonstrated in the chicken model of prenatal protein undernutr... Read more »

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Antibody
TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytopl...
Published: February, 2016

Abstract: The Tousled like kinase 1B (TLK1B) is critical for DNA repair and survival of cells. Upon DNA damage, Chk1 phosphorylates TLK1B at S457 leading to ... Read more »

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Article alert
Loss of the transcription factor Meis1 prevents sympathetic neurons...
Published: February, 2016

Abstract: Although cardio-vascular incidents and sudden cardiac death (SCD) are among the leading causes of premature death in the general population, the or... Read more »

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LowCell ChIP kit IPure kit
The transcription factor SOX6 contributes to the developmental orig...
Published: February, 2016

Abstract: The association between impaired fetal growth and postnatal development of obesity has been demonstrated before. By comparing adipocytes differenti... Read more »

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Bioruptor Article alert
Expression of the MOZ-TIF2 oncoprotein in mice represses senescence.
Published: February, 2016

Abstract: The MOZ-TIF2 translocation, that fuses MOZ (Monocytic Leukemia Zinc finger protein) histone acetyltransferase (HAT) with the nuclear co-a... Read more »

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Antibody
Desensitization and incomplete recovery of hepatic target genes aft...
Published: February, 2016

Abstract: Here, we examined changes in hepatic gene expression and serum TH/thyrotropin (TSH) levels in adult male mice treated either with a single T3 ... Read more »

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Bioruptor LowCell ChIP kit True MicroChIP kit
DNA methylation profiling of primary neuroblastoma tumors using met...
Published: February, 2016

Abstract: Comprehensive genome-wide DNA methylation studies in neuroblastoma (NB), a childhood tumor that originates from precursor cells of the sympathetic ... Read more »

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MethylCap
Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Dri...
Published: February, 2016

Abstract: BACKGROUND: The contribution of epigenetic factors, such as histone acetylation and DNA methylation, to the regulation of alcohol-drinking behavio... Read more »

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Antibody 5mC (C15200081)
Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease ...
Published: February, 2016

Abstract: In Graves' disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, charact... Read more »

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IP-Star
Protocol for Methylated DNA Immunoprecipitation (MeDIP) Analysis
Published: February, 2016

Abstract: DNA methylation is a fundamental epigenetic mechanism for silencing gene expression by either modifying chromatin structure to a repressive state o... Read more »

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Antibody 5mC (C15200081)
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CT...
Published: February, 2016

Abstract: Intragenic 5-methylcytosine and CTCF mediate opposing effects on pre-mRNA splicing: CTCF promotes inclusion of weak upstream exons through RNA poly... Read more »

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Antibody
The Nuclear Ribonucleoprotein SmD1 Interplays with Splicing, RNA Qu...
Published: February, 2016

Abstract: RNA quality control (RQC) eliminates aberrant RNAs based on their atypical structure, whereas posttranscriptional gene silencing (PTGS) eliminates ... Read more »

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IP-Star Compact
The dual specificity phosphatase 2 gene is hypermethylated in human...
Published: February, 2016

Abstract: Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulatio... Read more »

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Antibody
Diagenode® Premium RRBS technology: cost-effective DNA methylation ...
Published: January, 2016

Abstract: Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis in any vertebrate species. The assay benefits from... Read more »

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Premium RRBS Kit
DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylati...
Published: January, 2016

Abstract: While phosphorus in the form of inorganic or organic phosphate is critically involved in most cellular functions, high plasma levels of inorganic p... Read more »
DNMT3L enables accumulation and inheritance of epimutations in tran...
Published: January, 2016

Abstract: DNMT3L is an important epigenetic regulator in mammals, integrating DNA methylation and histone modification based epigenetic circuits. Here we sho... Read more »

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IP-Star
Rapid immunoprecipitation mass spectrometry of endogenous proteins ...
Published: January, 2016

Abstract: Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) is a method that allows the study of protein complexes, in particular chro... Read more »

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Bioruptor Bioruptor Plus
RNA biochemistry. Transcriptome-wide distribution and function of R...
Published: January, 2016

Abstract: Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs... Read more »

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Antibody
Transcriptome-wide distribution and function of RNA hydroxymethylcy...
Published: January, 2016

Abstract: Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs... Read more »

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Antibody
Chromatin Immunoprecipitation Assay for the Identification of Arabi...
Published: January, 2016

Abstract: Intricate gene regulatory networks orchestrate biological processes and developmental transitions in plants. Selective transcriptional activation a... Read more »

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Bioruptor Antibody
De novo DNA methylation drives 5hmC accumulation in mouse zygotes
Published: January, 2016

Abstract: Zygotic epigenetic reprogramming entails genome-wide DNA demethylation that is accompanied by Tet methylcytosine dioxygenase 3 (Tet3)-driven oxidat... Read more »

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Antibody 5mC (C15200081)
Analysis of EZH2: micro-RNA network in low and high grade astrocyti...
Published: January, 2016

Abstract: Enhancer of Zeste homologue2 (EZH2) is an epigenetic regulator that functions as oncogene in astrocytic tumors, however, EZH2 regulation remains li... Read more »

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Bioruptor LowCell ChIP kit True MicroChIP kit Article alert
The chloroplastic DEVH-box RNA helicase INCREASED SIZE EXCLUSION LI...
Published: January, 2016

Abstract: INCREASED SIZE EXCLUSION LIMIT 2 (ISE2) encodes a putative DEVH-box RNA helicase originally identified through a genetic screening for Arabidopsis ... Read more »

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IP-Star Compact
The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcript...
Published: January, 2016

Abstract: The interplay between methylation and demethylation of histone lysine residues is an essential component of gene expression regulation and there is... Read more »

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Antibody
Regulation of miR-200c/141 expression by intergenic DNA-looping and...
Published: January, 2016

Abstract: The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is int... Read more »

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MagMeDIP kit
DOT1L Activity Promotes Proliferation and Protects Cortical Neural ...
Published: January, 2016

Abstract: Growing evidence suggests that the lysine methyltransferase DOT1L/KMT4 has important roles in proliferation, survival, and differentiation of stem ... Read more »

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Antibody
Identification and validation of WISP1 as an epigenetic regulator o...
Published: January, 2016

Abstract: Lymph node (LN) metastasis is the most important prognostic factor in oral squamous cell carcinoma (OSCC) patients. However, in approximately one t... Read more »

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MethylCap
Molecular basis and functional significance of Angiotensin II-induc...
Published: January, 2016

Abstract: Delineation of mechanisms underlying the regulation of fibrosis-related genes in the heart is an important clinical goal as cardiac fibrosis is a m... Read more »

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LowCell ChIP kit

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