Genome-wide DNA methylation analysis in Graves' disease. Published: January, 2015 Abstract:
As an autoimmune disease, Graves' disease (GD) is associated with many genetic and environmental risk factors. Although the exact mechanism remains unclear, epigenetic determinants, such as DNA methylation, are thought to contribute to the pathoge... Read more » Tags DNA shearingBioruptorAntibody
Ultra-low-input native ChIP-seq for rare cell populations Published: January, 2015 Abstract:
Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell lines and tissue types. A major limitation of ChIP-seq, however, is the large number of cells required t... Read more » Tags AntibodyH3K27me3 (C15410069)
ChIPping Away at the Drosophila Clock Published: December, 2014 Abstract:
In eukaryotes, the circadian clock controls 24 h rhythms in physiology, metabolism, and behavior via cell autonomous transcriptional feedback loops. These feedback loops keep circadian time and control rhythmic outputs by driving rhythms in transc... Read more » Tags BioruptorChromatin ShearingChIP-qPCR
