Epigenetic mechanisms underlying learning and the inheritance of learned behaviors
In this review, researchers outline epigenetic mechanisms by which gene expression is regulated in animals and humans. Using fear learning as a framework, they show how such mechanisms underlie learning and stress responsiveness. Finally, they discuss how epigenetic mechanisms might inform us about the transgenerational inheritance of behavioral traits that are being increasingly reported. Trends in Neuroscience, 2014.
Epigenetic regulation of memory formation and maintenance
In the last decade, epigenetic markers like DNA methylation and post-translational modifications of histone tails have emerged as important regulators of the memory process. Their ability to regulate gene transcription dynamically in response to neuronal activation supports the consolidation of long-term memory.